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Impact of albumin levels on clinical outcomes in children underwent abdominal surgery Rismala Dewi; Freddy Guntur Mangapul Silitonga; Irawan Mangunatmadja
Paediatrica Indonesiana Vol 60 No 3 (2020): May 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.056 KB) | DOI: 10.14238/pi60.3.2020.149-53

Abstract

Background Patients underwent abdominal surgery and had hypoalbuminemia were at risk of post-operative complications. The prognostic role of albumin levels in children with abdominal surgery remains unclear. Objective To investigate the impact of albumin levels on clinical outcomes related to the complications in children with abdominal surgery. Methods This was a retrospective cohort study on children aged 29 days to 18 years, who underwent abdominal surgery, had serum albumin levels measured at pre-operative and within 48 hours post-operatively, and hospitalized in Paediatric Intensive Care Unit of Dr. Cipto Mangunkusumo Hospital, Indonesia. The primary outcomes were post-operative complications (sepsis, surgical site infection, shock), length of stay in PICU, dehiscence, relaparotomy, and postoperative mortality. Results This study recruited a total of 201 children. Pre- and post-operative serum albumin levels of ≤ 3.00 g/dL were found in 15.4% and 51.2%, respectively. Pre- and post-operative serum albumin levels of ≤ 3.00 g/dL were associated with higher risk of post-operative sepsis (RR 3.4; 95%CI 1.54 to 7.51) and relaparotomy (RR 3.84; 95%CI 1.28 to 1.49). The median of length of PICU stay was 4 days longer in children with pre-operative serum albumin levels ≤ 3.00 g/dL (P<0.001). Conclusions Hypoalbuminemia condition in children undergo abdominal surgery is associated with increased risk of post-operative sepsis, longer length of stay in PICU, and risk of relaparotomy.
Profil gas darah anak babi (Sus scrofa) setelah induksi sepsis dan resusitasi cairan Ega Iftahul Rizky; Rismala Dewi; . Gunanti; Riki Siswandi; Dwi Utari Rahmiati
ARSHI Veterinary Letters Vol. 2 No. 2 (2018): ARSHI Veterinary Letters - Mei 2018
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.477 KB) | DOI: 10.29244/avl.2.2.31-32

Abstract

Sepsis merupakan respon sistemik yang disebabkan oleh infeksi. Mortalitas sepsis dapat mencapai 30% meskipun telah dilakukan perawatan intensif. Renjatan sepsis adalah sepsis yang disertai dengan gangguan pada organ kardiovaskular dan respirasi. Penelitian ini bertujuan mengevaluasi parameter gas darah setelah induksi sepsis dan resusitasi cairan. Sebanyak 10 ekor anak babi dengan berat badan 10-13 kg dan umur 2-3 bulan dibagi menjadi dua kelompok perlakuan. Kelompok pertama diresusitasikan dengan cairan koloid modifikasi gelatin 4% (MFG 4%) sedangkan kelompok dua diresusitasikan dengan cairan kristaloid ringer asetat malat (RAM). Lipopolisakarida E. coli sebanyak 50 ug/kg berat badan diberikan dengan rute intravena untuk menginduksi terjadinya sepsis. Induksi sepsis menyebabkan penurunan pH dan PaO2, serta peningkatan PaCO2 dan laktat secara nyata (p<0.05). Resusitasi cairan dilakukan setelah renjatan sepsis. Resusitasi dengan cairan koloid dapat mengembalikan nilai PaCO2 dan PaO2 mendekati normal, serta menekan edema paru. Resusitasi dengan cairan koloid dinilai lebih baik karena dapat meminimalisir kerusakan yang terjadi akibat renjatan sepsis.
Indeks Eritrosit Anak Babi (Sus scrofa) yang Diinduksi Sepsis Pascaresusitasi Cairan Muhammad Abhi Purnomosidi; Rismala Dewi; . Gunanti; Riki Siswandi; Dwi Utari Rahmiati
ARSHI Veterinary Letters Vol. 1 No. 2 (2017): ARSHI Veterinary Letters - November 2017
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.481 KB) | DOI: 10.29244/avl.1.2.21-22

Abstract

Penelitian ini bertujuan untuk mengevaluasi indeks eritrosit (jumlah eritrosit, konsentrasi hemoglobin, hematokrit, VER, HER, KHER) pada anak babi (Sus scrofa) setelah diinduksi sepsis dan diresusitasi oleh cairan koloid (modified fluid gelatin 4%) atau kristaloid (ringer asetat malat). Sepuluh ekor anak babi berumur 2-3 bulan dengan berat badan 8-13 kg dibagi menjadi dua kelompok. Induksi sepsis dilakukan dengan injeksi endotoksin Eschericia coli melalui rute intravena hingga terjadi renjatan sepsis. Resusitasi cairan dilakukan pada saat renjatan sepsis terjadi melalui rute intravena. Kelompok pertama menerima resusitasi cairan menggunakan modified fluid gelatin 4% (MFG 4%) dan pada kelompok yang kedua menerima resusitasi cairan menggunakan cairan ringer asetat malat (RAM). Pengambilan sampel darah dilakukan pada saat setelah anestesi, saat sepsis, dan 3 jam setelah resusitasi cairan. Hasil evaluasi nilai indeks eritrosit menunjukkan bahwa hewan mengalami anemia makrositik regeneratif. Kondisi sepsis dan resusitasi cairan koloid (modified fluid gelatin 4%) maupun cairan kristaloid (ringer asetat malat) tidak memberikan pengaruh yang signifikan terhadap nilai indeks eritrosit.
Blood pressure to height ratio for screening hypertension among Indonesian adolescents Partini Pudjiastuti Trihono; Jeanne Laurensie Sihombing; Rismala Dewi
Paediatrica Indonesiana Vol 63 No 1 (2023): January 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.1.2023.7-12

Abstract

Background Pediatric hypertension is an emerging health issue due to its increasing prevalence. Age-, gender-, and height-specific blood pressure percentiles have been widely used as a primary tool for detection of hypertension in the pediatric population. However, this method is too complicated to be used in general pediatric practice. The blood pressure to height ratio has been proposed as a practical tool to detect hypertension in children. Objective To evaluate the accuracy of blood pressure to height ratio to be used as a tool for screening high blood pressure in Indonesian adolescents. Methods This diagnostic test study using data from the 2013 Indonesia Basic Health Research (Riset Kesehatan Dasar/RISKESDAS) report included 39,057 adolescents aged 15-18 years with complete data on age, gender, weight, height, and blood pressure. Blood pressure values were classified using the 2017 American Academy of Pediatrics (AAP) hypertension clinical guidelines. Blood pressure to height ratio was calculated as mmHg/cm body height. A receiver-operator characteristics (ROC) curve analysis was performed to assess the accuracy of systolic blood pressure to height ratio (SBPHR) and diastolic blood pressure to height ratio (DBPHR) for screening high blood pressure in adolescents. The optimal cut-off points, sensitivity, and specificity of SBPHR and DBPHR were calculated. Results The optimal cut-off points for defining elevated blood pressure in male adolescents aged 13-18 years were SBPHR 0.69 for male adolescents (sensitivity 96%, specificity 80%) and DBPHR 0.46 (sensitivity 97%, specificity 84%). In female adolescents, the optimal cut-offs were SBPHR 0.72 (sensitivity 97%, specificity 82%) and DBPHR 0.48 (sensitivity 98% and specificity 79%). Conclusion Blood pressure to height ratio is a practical method with high sensitivity and specificity for detecting elevated blood pressure in Indonesian adolescents aged 15 to 18 years.
The Effectiveness of Implementing Family-Centered Rounds in the PICU on Parental Satisfaction Arvina Novianti; Sita Febriani; Hermin Mardiana; Rismala Dewi; Dina Nurpita Suprawoto
Journal of Nursing Science Update (JNSU) Vol. 11 No. 1 (2023): May
Publisher : Department of Nursing, Faculty of Health Sciencce, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jik.2023.011.01.4

Abstract

Family-Centered Care (FCC) is needed in nursing care for children with critical illnesses in the PICU, but the implementation of FCC has yet to be effective. This is due to family visit restrictions, direct care involvement, and decision-making. Family- Centered Rounds (FCR) are a multidisciplinary professional approach to decision-making by facilitating family involvement in medical decision-making. This study aims to analyze the effectiveness of implementing FCR in the PICU on patients' parents' satisfaction. This study used a quantitative experimental design in which Randomized Controlled Trial (RCT) design with a post-test-only control group was used. Sixty-four parents of patients in the PICU unit at RSCM were recruited by consecutive sampling and randomly assigned to two treatments (room standard intervention for the control group and FCR for the intervention group). Treatment in both groups was carried out for two days then the satisfaction level of parent respondents was measured using the Pediatric Family Satisfaction in intensive care Unit 24 (pFS-ICU 24). Bivariate analysis used an independent t-test to analyze differences in family satisfaction scores in both groups. Statistically, there was a significant difference in the mean score of patient family satisfaction between groups with FCR and no FCR with p=0.001 (p<0.05). It was concluded that FCR was effectively carried out, which impacted increasing the satisfaction of the patient's parents. FCR is very effectively implemented in the PICU unit as a development of the application of the FCC concept, which can benefit the patient's family.
Tinjauan COVID-19 pada Anak: Infeksi hingga Terapi Rismala Dewi
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-297

Abstract

Coronavirus disease 2019 (COVID-19) is an acute respiratory infection which is caused by SARS-CoV-2 virus. Studies showed that the transmission of the virus is from human to human the primary transmission of SARS-CoV-2 infection is via droplets produced by sneezing or coughing. There is a possibility that COVID-19 can be transmitted through aerosol or airborne transmission. The incubation period of this infection is predicted to be between 3-14 days after close contact. Patients with COVID-19 could have various clinical manifestations from asymptomatic to respiratory failure. Although a few cases revealed that COVID-19 could result in critical condition, COVID-19 is relatively mild in children. Physicians must diagnose and assess the clinical severity of the patient with SARS-CoV-2 infection as it affects the management of the disease. Several anti-viral medicines that might be effective in treating COVID-19 patients such as Remdesivir, Chloroquine/Hydroxychloroquine, Lopinavir-Ritonavir, and Tocilizumab are currently still on trial. It is also crucial to prevent the spread of COVID-19 by encouraging people to apply hand-hygiene, practice social distancing, and disinfect all possible sources.
Hubungan Antara Nilai Leukosit, Rasio Jumlah Neutrofil-limfosit (NLR), C-Reactive Protein (CRP) dan Prokalsitonin dengan Skor Pediatric Logistic Organ Dysfunction (PELOD-2) sebagai Prediktor Derajat Keparahan Penyakit pada Anak Sakit Kritis Rismala Dewi; Risa Imanillah
Majalah Kedokteran Indonesia Vol 71 No 1 (2021): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.71.1-2021-343

Abstract

Introduction: Children admitted to the Pediatric Intensive Care Unit (PICU) are a vulnerable population with a high degree of morbidity and mortality. Laboratory tests such as full blood count and infection parameters were additional tests that help clinicians assess the severity of pediatric patients’ illnesses. Besides that, the PELOD-2 score, a scoring system, also helped evaluate the degree of a critical condition in children. However, the components of PELOD-2 are quite complicated and unattainable in the limited-resource healthcare facilities. We expect that the simple laboratory examinations could be an alternative to the PELOD-2 score when the score is not accessible. This study evaluates the correlation between leukocyte count, Neutrophil-Lymphocyte Ratio, CRP, and PELOD-2 score. Methods: This is a comparative retrospective study in 75 pediatric patients admitted in PICU RSCM from January 2019 to August 2020 and passed the ethical review. The exclusion criteria for this research was a patient with incomplete data. To analyze the variables independently, we used Spearman analysis. Meanwhile, to evaluate the relationship between the independent variables and PELOD-2 simultaneously, we used logistic regression. Results: Based on the Spearman analysis, this study found a significant correlation between Leukocyte count (0,059; CI:90%) and PELOD-2 score, as well as Procalcitonin (0,076; CI: 90%) and PELOD-2. The logistic regression also showed that Leukocyte count and Procalcitonin significantly correlated with the PELOD-2 score.Conclusion: Leukocyte count and Procalcitonin can be an alternative to the PELOD-2 score when healthcare facilities cannot fulfil the PELOD-2 scoring system’s components.
Gigitan Ular: Manajemen Terkini Niken Wahyu Puspaningtyas; Rismala Dewi; Ashfahani Imanadhia
Majalah Kedokteran Indonesia Vol 72 No 2 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.2-2022-386

Abstract

Snakebite is declared as neglected tropical disease by WHO in 2009. Limited report and collection data about the exact number of snakebite national incidents shows that this case lacking of attention. Moreover, control program, management, also proper treatment have not been understood by public and health workers. In fact, snakebite is a medical emergency that can lead to permanent disability, limb amputation, and even death. For this reason, effort are needed to reduce morbidity and mortality that arise through preventive, curative, including comprehensive understanding of related proper, safe, and effective case management.
Precision and accuracy of transcutaneous CO2 monitoring in infants born at 32-36 weeks of pregnancy on respiratory support Lubis, Syamsidah; Kaban, Risma Kerina; Dewi, Rismala; Putri, Ruth Angelia
Paediatrica Indonesiana Vol. 64 No. 2 (2024): March 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.2.2024.160-7

Abstract

Background Respiratory disorders in premature neonates often require respiratory support. Continous transcutaneous monitoring is an available non-invasive option to monitor CO2 pressure, substituting the need for blood gas analysis as the gold standard evaluation in practice. Most studies have been conducted on very and extremely preterm neonates, but rarely in late and moderately preterm neonates. Objective To determine the precision and accuracy of transcutaneous CO2 pressure measuring devices compared to arterial blood gas analysis in neonates of 32-36 weeks gestational age who received respiratory support. Methods This diagnostic, cross-sectional study was conducted on 35 late and moderately preterm neonates of 32–36 weeks gestation who received cardiopulmonary resuscitation (CPR) in the Neonatology Unit at Rumah Sakit Cipto Mangunkusumo, Jakarta. Subjects were monitored with a transcutaneous CO2 monitor and blood gas analysis (BGA). CO2 pressure measurements were made three times from the two devices. Data were analyzed using Spearman’s correlation and Bland-Altman tests to determine the precision and accuracy of transcutaneous monitoring by comparing its mean difference (MD) to BGA as the gold standard measurement. Results Spearman’s analysis revealed a significant positive correlation between BGA and transcutaneous CO2 monitoring (P<0.001). However, the Bland - Altman test revealed a level of agreement between measuring devices was -14.46 to 6.9, with mean difference of -3.78; indicating poor precision of the transcutaneous evaluation regardless its high accuracy compared to its gold standard. Conclusion The transcutaneous CO2 monitoring device has low precision, but a strong positive correlation to BGA; underlining its high accuracy in practice. Transcutaneous CO2 monitoring cannot replace BGA, the gold standard examination.
PENGEMBANGAN BAHAN AJAR MATERI BILANGAN BULAT BERBASIS PMRI MENGGUNAKAN KONTEKS WISATA MUSI RAWAS Dewi, Rismala; Sukasno, Sukasno
JP2M (Jurnal Pendidikan dan Pembelajaran Matematika) Vol 10, No 2 (2024)
Publisher : Universitas Bhinneka PGRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29100/jp2m.v10i2.5813

Abstract

This research emphasizes teaching materials that are conceptual in nature and do not use a context that is close to students. The research objective is to produce PMRI-based teaching material products about integers. The research subjects were class III students at SD Negeri 31 Lubuklinggau. The research design uses the ADDIE research and development model with 5 stages, namely analysis, design, development, implementation and evaluation. Data collection uses interviews and questionnaires. Validation and practicality questionnaire instruments are used to measure the validity and practicality of PMRI-based teaching materials. Based on the results of the validity data analysis carried out by the three experts, their respective scores were obtained, namely media experts got a score of 0.88, language experts got a score of 0.83 and material experts got a score of 0.75. The results of the analysis of the small group practicality questionnaire data obtained an average score of 89% and the teacher response practicality questionnaire data obtained an average score of 95%. Thus, it can be concluded that the PMRI-based integer teaching materials using the Musi Rawas tourism context are valid and practical so that they can be declared suitable for use.
Co-Authors Abdul Latief Abdul Latief Abriyanto, Abriyanto Adam Adam Aditya Wardhana Afif, Ahmad Ainul Alan Roland Tumbelaka Amir S. Madjid, Amir S. Andina Judith Andriani, Adinda Viviana Antonius H. Pudjiadi Antonius Pudjiadi Arie Dian Fatmawati Arvina Novianti Arwin A.P Akib Ashfahani Imanadhia Badriul Hegar Bambang Supriyatno Cahyani Gita Ambarsari Cindy D. Christie Corry Wawolumaya Damayanti Rusli Sjarif Darmawan B Setyanto Darmawan B. Setyanto Dina Nurpita Suprawoto Dwi Utari Rahmiati Ega Iftahul Rizky Eka Laksmi Hidayati, Eka Laksmi Endah Sulistiawati Evita Kariani B. Ifran Fatimatuzzuhroh Fatimatuzzuhroh Freddy Guntur Mangapul Silitonga Gunanti . Hanifah Oswari Hartono Gunardi Hartono Gunardi Helen Dian Fridayani, Helen Dian Hermin Mardiana Hidayat, Nauval Edghina Hotber Pasaribu I Nyoman Budi Hartawan Ifran, Evita Kariani Imam D Imam N Iqbal Zein Assyidiqie Irawan Mangunatmadja Irawan Mangunatmadja Irene Yuniar, Irene Iskandar, Stephen Diah Jayanti, Reny Dwi Jeanne Laurensie Sihombing Jose M. Mandei Julianti Julianti, Julianti Kaltha, Karina Kusumaningrum, Alya Laila Laila Marissa Tania Stephanie Pudjiadi Misbah Muhammad Abhi Purnomosidi Mulya R. Karyanti Munar Lubis Nabilla Novella Riyanti Nathanne Septhiandi Niken Wahyu Puspaningtyas Novie Amelia Nycane Nycane oedjatmiko oedjatmiko Partini Pudjiastuti Trihono Piprim B Yanuarso Piprim B. Yanuarso, Piprim B. Purwasari, Lucy Asri Putri, Ruth Angelia Riki Siswandi Rina Amalia C. Saragih Rinawati Rohsiswatmo Rini Sekartini Risa Imanillah Risma Kerina Kaban, Risma Kerina Ronald Chandra Rosalina Dewi Roeslani, Rosalina Dewi Sita Febriani Sudung O Pardede, Sudung O Sudung O. Pardede Sukasno Sukasno Syafiqurosyid, M. Zufar Syamsidah Lubis, Syamsidah Teny Tjitra Teny Tjitra Sari, Teny Tjitra Tidi Maharani, Tidi Tjhin Wiguna Wahyuni Indawati Wardah, Nabila Amalya Wardhana, Aditya Widjaya, Malik Wisnu