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All Journal Hemera Zoa Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Afiasi : Jurnal Kesehatan Masyarakat Jurnal Sibermas (Sinergi Pemberdayaan Masyarakat) International Journal of Health, Economics, and Social Sciences (IJHESS) Madu : Jurnal Kesehatan Indonesian Journal of Pharmaceutical Education Jurnal Kolaboratif Sains Jurnal Pengabdian Kesehatan Masyarakat International Journal of Health Science & Medical Research Madani: Jurnal Pengabdian Ilmiah. JHTS Jurnal Ilmu Manajemen dan Bisnis Innovative: Journal Of Social Science Research Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi
Laksmyn Kadir
Universitas Negeri Gorontalo
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WAAC-5 Flushing Aquaria with Hibiscus sabdariffa Extract on TNFα Expression in Fish Due To Mercury Intoxication Olan Rahayu Puji Astuti Nussa; Miranti Candrarisna; Laksmyn Kadir
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Abstract

The purpose of this study was to determine the expression of TNFα in the gills and liver tissue and the fish acute intoxication due to mercury, post-treatment using Rosella extract and flushing aquaria. It was an experimental study with a posttest only control group design consisting of 30 adult male fishes. There are 5 groups treatment including: P0 (healthy); P1 (mercury without Rosella extract and flushing; P2 (given mercury and Rosella extract of 5 ppm and flushing); P3 (given mercury and Rosella extract of 10 ppm and flushing); P4 (given mercury and Rosella extract of 20 ppm and flushing). Each group performed necropsy and examination immunohistochemical in the fish’s gills and liver on the 7th day after induction with mercury and on the 15th day of post-therapy using Rosella extract with flushing Aquaria. The results showed TNFα expression in the gills was different significantly and the the number was increasing compared to TNFα in the liver. The decrease of TNFα expression in the gills and liver were significantly different in the P4 group when compared to the other groups. In conclusion, Flushing aquaria and Rosella extract can reduce the TNFα expression in the fish’s gills and liver which experiencing mercury intoxication. Flushing Aquaria technology is a very appropriate method used for therapeutic in aquatic animals.
Co-Authors Adnan Malaha Agusrianto Yusuf Alma Jihan Akili Ana Pepiana Ayu Rofia Nurfadillah Dewi Rahmawaty Moo Dewi Wahyuni K. Baderan Diah Noorshanti Moo Fadiyah Faisal Anoez Alamri Fatrawaty Baruadi hasan, wahyunihasa I Made Ari Setiawan Imam Mashudi Indah Dwi Amalia Indi Rahmawati Tobuto Indra Saputra S. Mayulu Irwan Irwan Julianty Akuba La Ode Sultan Lanjahi, Nurhayati Laode Sultan Lia Amalia Lintje Boekoesoe Lisda Van Gobel Meity Tombinawa Meylani Toonawu Miranti Candrarisna Moh Arif Dulambuti Moh. Rivai Nakoe Mutiara Fadillah Hadju Mutya Rahma Wati Manan Nadila Salsabila Mongilong Nikmatisni Arsad Novriyanti Adam Nur Ayini S Lalu Nur Hairunnisa Abaidatai Nurafrinda Djabar Nurul Wulandari Wahyuddin Olan Rahayu Puji Astuti Nussa Paramita Ismail Putri Ayuningtias Mahdang Putri Ayuningtiyas Mahdang Putri Rachmawaty Rahmawanto Taidi Ramly Abudi Rohana Pakaya Sarinah Basri K Septian Robot Siti Magfira Cahya Mantune Siti Surya Indah Nurdin Sofianti Talibo Sri Ulva Ahmad Sri Wahyuni Dengo Sunarto Kadir Supantri Hako Tasya Karim Tri Septian Maksum wahyunihasa hasan Widya Mardiyanti Domili Wiharsri Wina Ratri A. Ismail Wirnangsih D. Uno Yasir Mokodompis Yosef P. Koton Yosefus Kristiawan Yosep P. Koton Yunus, Deis Zulfikar Ahmad