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Efek Ekstrak Etanol Daging Putih Semangka dan Simvastatin Terhadap Aktivasi Nuclear Factor Kappa Beta (NF- kβ) Aorta Tikus Rattus Norvegicus yang Diberi Diet Aterogenik Manggasa, Dafrosia Darmi
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 2 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Atherogenic diet can lead to dyslipidemia condition that trigger increase Reactive Oxygen Species (ROS) and oxidative stress. The increasing of ROS can activate transcription factor Nuclear Factor Kappa Beta (NF-kβ). Activated NF-kβ induce proinflammatory cytokines that will increase the atherosclerosis progressivity. Watermelon rind had proven to have antioxidant compounds that can inhibit ROS. This study was aimed to prove the effect of watermelon rind extract and simvastatin to decrease the NF-kβ aktivation of Rattus norvegicus with atherogenic diet. This research was using Post Test Only Control Group Design. The samples were divided into five groups: (i) standard diet (K(-)), (ii) atherogenic diet (K(+)), (iii) atherogenic diet + watermelon rind extract 250 mg/kgBW/day, (iv) atherogenic diet + watermelon rind 500 mg/kgBW/day, and (v) the atherogenic diet + simvastatin 0.9 mg/kgBW/day. Atherogenic diet was given for 8 weeks. NF-kβ were measured by immunohistochemistry. Data were analyzed with ANOVA and post hoc test. The results showed a significant decrease mean NF-kβ activation after treatment of watermelon rind extract of 250 mg/kg/day (p =0,000), dose of 500 mg/kg/day (p = 0.000), and simvastatin dose of 0.9 mg/kg/day could reduced NF-kβ significantly (p = 0,000) compared with atherogenic diet group. It concluded that the watermelon rind extract dose 500 mg/kgBW/day was equivalent to simvastatin 0,9 mg/kgBW/day in lowering the NF-kβ activation rats with atherogenic diet.

Kombinasi Swedish Massage dan Aromaterapi Lemon untuk Menurunkan Nyeri Post Sectio Caesarea: Combination of Swedish Massage and Lemon Aromatherapy to Reduce Post Sectio Caesarea Pain Manggasa, Dafrosia Darmi
Jurnal Bidan Cerdas Vol. 3 No. 2 (2021)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jbc.v3i2.399

Introduction: Artificial delivery with the Sectio Caesarea (SC) procedure can cause pain in the patient. Pain that is left untreated can have a negative impact on both the mother and the baby. Pain management can also use massage or aromatherapy interventions that provide a relaxing effect. This study aims to assess the effectiveness of combined therapy Swedish massage and lemon aromatherapy in reducing post-SC pain. Methods: Quasi-experimental design with two groups pre-post test. This study was conducted at Poso Regional Hospital from October to December 2019. The sample was 32 post-SC patients who experienced pain who were taken using the purposive sampling technique. Swedish massage intervention was carried out 4 times. The pain was measured before intervention and after intervention using the Numeric Rating Scale. Data analysis used the Wilcoxon and Mann-Whitney tests. Results: This study showed that the intervention group with combined therapy Swedish massage and lemon aromatherapy showed a significant reduction in pain scores with a mean after the intervention of 3.19 and in the control group with Swedish massage only the mean value was 3.88, statistical analysis obtained p-value 0.031. Conclusion: The combined therapy Swedish massage and lemon aromatherapy is effective in reducing the pain score of post-SC patients, so it is suggested to be one of the nursing interventions to reduce post-SC pain

Penerapan Swedish Massase dengan Menggunakan Minyak Zaitun terhadap Risiko Kerusakan Integritas Kulit pada Asuhan Keperawatan Pasien dengan Kasus Stroke: Implementation of Swedish Massage using Olive Oil to the Risk of Skin Integrity Damage in Patient Nursing Caring with Stroke Dewi, Dewi Nurviana Suharto; Manggasa, Dafrosia Darmi; Agusrianto, Agusrianto; Suharto, Vita Fadila
Poltekita : Jurnal Ilmu Kesehatan Vol. 14 No. 2 (2020): October
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v14i2.224

Stroke merupakan deficit neurologis akibat ketidakefektifan sirkulasi darah otak dikarenakan adanya iskemia atau hemoragik. Defisit neurologis yang dialami pasien stroke secara langsung akan menimbulkan masalah hemiparese. Hemiparese akan menyebabkan pasien mengalami imobilisasi. Imobilisasi menyebabkan pasien beresiko untuk mengalami luka tekan. Perawatan kulit dengan massage merupakan salah satu intervensi keperawatan yang efektif untuk mencegah terjadinya luka tekan. Salah satu tehnik massage yang sering digunakan adalah Swedish massage dengan menggunakan minyak zaitun. Tujuan penelitian adalah untuk Mengetahui Kefektifan Penerapan Swedish Massase dengan Olive Oil terhadap Resiko Kerusakan Integritas Kulit pada Asuhan Keperawatan Pasien dengan Kasus Stroke di RSUD Poso. Metode Penelitian adalah Studi Kasus. Subjek adalah pasien stroke dengan imobilisasi. Hasil pengkajian yang didapat yaitu kelemahan badan sebelah kanan, seluruh aktivitas dibantu. Diagnosa yang ditegakan hambatan mobilitas fisik. Intervensi yang disusun yaitu menejeman area penekanan. Implementasi yaitu pemberian tindakan Swedish Massase dengan Olive Oil 2 kali sehari selama 6 hari, dengan masalah resiko kerusakan integritas kulit nilai 1 (tidak terjadi). Setelah dilakukan tindakan Swedish massase dengan olive oil selama 5 hari masalah risiko kerusakan integritas kulit teratasi dengan kriteria, integritas kulit utuh, perfusi jaringan baik, suhu dan kelembaban kulit terjaga. Diharapkan tindakan Swedish massase dengan olive oil dapat menjadi salah satu intervensi keperawatan terprogram untuk mencegah resiko kerusakan integritas kulit pada pasien stroke di RSUD Poso.

Kombinasi Contrast Bath dengan Foot Massage Menurunkan Edema Kaki Pada Pasien Congestive Heart Failure Manggasa, Dafrosia Darmi; Agusrianto, Agusrianto; Djua, Muhamad Fikran
Poltekita : Jurnal Ilmu Kesehatan Vol. 15 No. 1 (2021): May
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v15i1.419

Tujuan penelitian menilai efektifitas kombinasi terapi contrast bath dengan foot massage dalam menurunkan edema kaki pada pasien CHF. Metode peneltiian quasi eksperimen desain two group pre-post test. Penelitian di laksanakan di RSUD Poso bulan Januari â€“April 2021. Sampel yaitu pasien CHF yang mengalami edema kaki sebanyak 30 orang dibagi dalam 2 kelompok yaitu kelompok kontrol dan kelompok perlakuan. Kelompok perlakuan mendapatkan intervensi kombinasi contrast bath dengan foot massage. Hasil peneltiian menunjukkan reerata nilai lingkar kaki pada kelompok perlakuan sebelum intervensi yaitu 22,37 cm dan setelah intervensi 21,59 cm. Hasil uji statistik terdapat perbedaan yang signifikan rerata nilai lingkar kaki sebelum dan setelah intervensi (p = 0,000). Pada kelompok perlakuan rerata kedalaman edema kaki sebelum intervensi 4,97 cm dan setelah intervensi 2,07 cm. Hasil uji statistik terdapat perbedaan yang signifikan rerata kedalaman edema kaki kaki sebelum dan setelah intervensi (p = 0,000). Kesimpulan yaitu kombinasi contrast bath dengan foot massage efektif menurunkan edema kaki pada pasien CHF. Kombinasi contrast bath dengan foot massage dapat diterapkan oleh perawat di Rumah Sakit untuk menurunkan edema kaki pada pasien

Bantuan Kemanusiaan Korban Banjir Bandang di Sulawesi Tengah: Humanitarian Assistance for Flash Flood Victims in Central Sulawesi Fahmi Hafid; Nasrul Nasrul; Aminudin Aminudin; Amsal Amsal; Masudin Masudin; Gusman Gusman; Sova Evie; Kadar Ramadhan; Hamsiah Hamsiah; Junaidi Junaidi; Zainul Zainul; Lisnawati Lisnawati; Putu Candriasih; Nurjaya Nurjaya; Elvyrah Faisal; Linda Linda; Moammar Safari; Supriadi Abd Malik; Andi Fatmawati; Hasnawati Hasnawati; Selvi Alfrida Mangundap; Mardani Mangun; Fajrillah Kolomboy; Dedi Mahyudin Syam; Hastuti Usman; Nurarifah Nurarifah; Tjitrowati Djaafar; Niluh Nita Silfia; Lili Suryani; Sri Restu Tempali; Sigit M. Nuzul; Lisda Widianti Longgupa; Hadina Hadina; Sri M. Hasan; Hadriani; I Wayan Supetran; Mercy Joice Kaparang; Lindanur Sipatu; Baharuddin Condeng; Azizah Saleh; Siti Hadijah Batjo; Djadid Subchan; Anna Veronika Pont; Olkamien J. Longulo; Novarianti Novarianti; Supriadi; Wijianto Wijianto; Sri Yanti Kusika; Henrietta Imelda Tondong; Christina Entoh; Nurfatimah Nurfatimah; Masda Masda; Saman Saman; Yasmin H Yasmin H; Azwar Azwar; Hasni Hasni; Ekasari Dewi Pertiwi; Rusneni; Raoda; Hasdrini; Salman; Irsanty Collein; Yulianus Sudarman H Melangka; Christine; Taqwin Taqwin; Hanum Sasmita; Asri Widyayanti; Ros Arianty; Dwi Kartika; Baiq Emy; Diah Ayu Hartini; Sukmawati; Nitro Galenso; Wery Aslinda; Indro Subagyo; Elfyrah Faisal; Ansar Ansar; Bahja Bahja; Dwi Erma Kusumawati; Agusrianto Agusrianto; Nirva Rantesigi; Rina Tampake; Sony Bernike Magdalena Sitorus; Helena Pangaribuan; Firdaus Hi Jahja Kunoli; Hasbunsyah Hasbunsyah; Metrys Ndama; Nurindah Nurindah; Diana Nurhayati Sinurat; Asrawaty Asrawaty; Abd Farid Lewa; Muliani Muliani; Eka S. Riyanto; Dafrosia Darmi Manggasa; Ni Made Ridla Nilasanti Purwata
Poltekita: Jurnal Pengabdian Masyarakat Vol. 3 No. 2 (2022): April-Juni
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

The flash flood disaster hit Galumpang Village, Aung Village and Bajungan Village in Tolitoli Regency, Central Sulawesi on Wednesday morning 23 March 2022. Due to the large number of victims of flash floods and the urgent needs of victims of flash floods, the Civitas Academic of Poltekkes Kemenkes Palu provided humanitarian aid for victims of flash floods in Tolitoli Regency, Central Sulawesi. Humanitarian assistance in the form of ready-to-eat food, rice, Toothpaste, Soap, Sunlight, Shampoo, Sweetened Condensed Milk, Tea, Sugar, Bucket, Dipper, Mask and Pampers Children under two. The assistance was handed over by the Chief Community Service Officer to the Head of Galumpang Village on April 1, 2022 at the Disaster Management Command Post in Galumpang Village, Dakopamean District, Tolitoli Regency, Central Sulawesi. The flash flood victim’s community as beneficiaries have received assistance from the Poltekkes Kemenkes Palu Academic Community through Community Service activities. ABSTRAK Bencana banjir bandang telah menghantam Desa Galumpang, Desa Aung dan Desa Bajungan di Kabupaten Tolitoli, Sulawesi Tengah pada Rabu dini hari tanggal 23 Maret 2022. Oleh karena besarnya jumlah korban banjir bandang dan kebutuhan korban banjir bandang yang mendesak, maka Civitas Akademika Poltekkes Kemenkes Palu memberikan bantuan kemanusiaan korban banjir bandang di Kabupaten Tolitoli Sulawesi Tengah. Bantuan kemanusian berupa makanan siap saji, beras, Pasta Gigi, Sabun, Sunlight, Shampoo, Susu Kental Manis, Teh, Gula Pasir, Ember, Gayung, masker dan Pampers Baduta. Bantuan diserahkan oleh Ketua Pelaksana Pengabdian Masyarakat kepada Kepala Desa Galumpang pada tanggal 01 April 2022 di Posko Induk Penanggulangan Bencana Desa Galumpang Kecamatan Dakopamean Kabupaten Tolitoli, Sulawesi Tengah. Masyarakat korban banjir bandang sebagai penerima manfaat telah menerima bantuan dari Civitas Akademika Poltekkes Kemenkes Palu melalui kegiatan Pengabdian Masyarakat.

Kombinasi Swedish Massage dan Aromaterapi Lemon untuk Menurunkan Nyeri Post Sectio Caesarea: Combination of Swedish Massage and Lemon Aromatherapy to Reduce Post Sectio Caesarea Pain Dafrosia Darmi Manggasa
Jurnal Bidan Cerdas Vol. 3 No. 2 (2021)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jbc.v3i2.399

Introduction: Artificial delivery with the Sectio Caesarea (SC) procedure can cause pain in the patient. Pain that is left untreated can have a negative impact on both the mother and the baby. Pain management can also use massage or aromatherapy interventions that provide a relaxing effect. This study aims to assess the effectiveness of combined therapy Swedish massage and lemon aromatherapy in reducing post-SC pain. Methods: Quasi-experimental design with two groups pre-post test. This study was conducted at Poso Regional Hospital from October to December 2019. The sample was 32 post-SC patients who experienced pain who were taken using the purposive sampling technique. Swedish massage intervention was carried out 4 times. The pain was measured before intervention and after intervention using the Numeric Rating Scale. Data analysis used the Wilcoxon and Mann-Whitney tests. Results: This study showed that the intervention group with combined therapy Swedish massage and lemon aromatherapy showed a significant reduction in pain scores with a mean after the intervention of 3.19 and in the control group with Swedish massage only the mean value was 3.88, statistical analysis obtained p-value 0.031. Conclusion: The combined therapy Swedish massage and lemon aromatherapy is effective in reducing the pain score of post-SC patients, so it is suggested to be one of the nursing interventions to reduce post-SC pain

Kombinasi Contrast Bath dengan Foot Massage Menurunkan Edema Kaki Pada Pasien Congestive Heart Failure Dafrosia Darmi Manggasa; Agusrianto Agusrianto; Muhamad Fikran Djua
Poltekita : Jurnal Ilmu Kesehatan Vol. 15 No. 1 (2021): May
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v15i1.419

Tujuan penelitian menilai efektifitas kombinasi terapi contrast bath dengan foot massage dalam menurunkan edema kaki pada pasien CHF. Metode peneltiian quasi eksperimen desain two group pre-post test. Penelitian di laksanakan di RSUD Poso bulan Januari –April 2021. Sampel yaitu pasien CHF yang mengalami edema kaki sebanyak 30 orang dibagi dalam 2 kelompok yaitu kelompok kontrol dan kelompok perlakuan. Kelompok perlakuan mendapatkan intervensi kombinasi contrast bath dengan foot massage. Hasil peneltiian menunjukkan reerata nilai lingkar kaki pada kelompok perlakuan sebelum intervensi yaitu 22,37 cm dan setelah intervensi 21,59 cm. Hasil uji statistik terdapat perbedaan yang signifikan rerata nilai lingkar kaki sebelum dan setelah intervensi (p = 0,000). Pada kelompok perlakuan rerata kedalaman edema kaki sebelum intervensi 4,97 cm dan setelah intervensi 2,07 cm. Hasil uji statistik terdapat perbedaan yang signifikan rerata kedalaman edema kaki kaki sebelum dan setelah intervensi (p = 0,000). Kesimpulan yaitu kombinasi contrast bath dengan foot massage efektif menurunkan edema kaki pada pasien CHF. Kombinasi contrast bath dengan foot massage dapat diterapkan oleh perawat di Rumah Sakit untuk menurunkan edema kaki pada pasien

Riwayat Pengobatan dan Komorbid Diabetes Mellitus Berhubungan Dengan Kejadian Tuberkulosis Resisten Obat Dafrosia Darmi Manggasa; Dewi Nurviana Suharto
Poltekita : Jurnal Ilmu Kesehatan Vol. 15 No. 4 (2022): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v15i4.659

Tujuan penelitian untuk menganalisis hubungan antara riwayat pengobatan Tuberkulosis (TB) sebelumnya dan komorbid Diabetes Mellitus (DM) dengan kejadian Tuberkulosis Resisten Obat (TB RO) di Kabupaten Poso. Metode penelitian yaitu observasional analitik dengan desain studi case control. Populasi yaitu seluruh pasien penderita TB di Kabupaten Poso. Sampel yaitu 32 pasien TB RO sebagai kelompok kasus dan 32 penderita TB Sensitifi Obat (TB SO) sebagai kelompok kontrol. Pengambilan data dengan mengidentifikasi data Sistem Informasi Tuberkulosis (SITB). Analisis statistik menggunakan uji chi Square. Hasil penelitian menunjukkan pasien TB yang pernah menjalani pengobatan sebelumnya yaitu TB RO sebesar 65,5% dan TB SO sebesar 18,8%, dengan nilai p = 0,000, pasien TB yang tidak teratur minum obat yaitu TB RO sebesar 71,9% dan TB SO sebesar 15,6% dengan nilai p = 0,000, pasien TB yang menderita komorbid DM yaitu TB RO sebesar 31,3% dan TB SO sebesar 6,3% dengan nilai p = 0,025. Kesimpulan terdapat hubungan antara riwayat pengobatan sebelumnya dan adanya komorbid DM dengan kejadian TB RO pada pasien TB di Kabupaten Poso. Saran agar fasilitas pelayanan kesehatan meningkatkan manajemen program layanan TB untuk menjamin keteraturan minum obat sehingga mencegah terjadinya TB RO.

Efek Ekstrak Etanol Daging Putih Semangka dan Simvastatin Terhadap Aktivasi Nuclear Factor Kappa Beta (NF- kβ) Aorta Tikus Rattus Norvegicus yang Diberi Diet Aterogenik Dafrosia Darmi Manggasa
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 2 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Atherogenic diet can lead to dyslipidemia condition that trigger increase Reactive Oxygen Species (ROS) and oxidative stress. The increasing of ROS can activate transcription factor Nuclear Factor Kappa Beta (NF-kβ). Activated NF-kβ induce proinflammatory cytokines that will increase the atherosclerosis progressivity. Watermelon rind had proven to have antioxidant compounds that can inhibit ROS. This study was aimed to prove the effect of watermelon rind extract and simvastatin to decrease the NF-kβ aktivation of Rattus norvegicus with atherogenic diet. This research was using Post Test Only Control Group Design. The samples were divided into five groups: (i) standard diet (K(-)), (ii) atherogenic diet (K(+)), (iii) atherogenic diet + watermelon rind extract 250 mg/kgBW/day, (iv) atherogenic diet + watermelon rind 500 mg/kgBW/day, and (v) the atherogenic diet + simvastatin 0.9 mg/kgBW/day. Atherogenic diet was given for 8 weeks. NF-kβ were measured by immunohistochemistry. Data were analyzed with ANOVA and post hoc test. The results showed a significant decrease mean NF-kβ activation after treatment of watermelon rind extract of 250 mg/kg/day (p =0,000), dose of 500 mg/kg/day (p = 0.000), and simvastatin dose of 0.9 mg/kg/day could reduced NF-kβ significantly (p = 0,000) compared with atherogenic diet group. It concluded that the watermelon rind extract dose 500 mg/kgBW/day was equivalent to simvastatin 0,9 mg/kgBW/day in lowering the NF-kβ activation rats with atherogenic diet.

PEMBERDAYAAN MASYARAKAT DALAM PEMBENTUKAN DESA CERDAS LAWAN COVID-19 Dewi Nurviana Suharto; Agusrianto Agusrianto; Dafrosia Darmi Manggasa; Nirva Rantesigi
JMM (Jurnal Masyarakat Mandiri) Vol 6, No 3 (2022): Juni
Publisher : Universitas Muhammadiyah Mataram

Abstrak: Peningkatan jumlah kasus COVID-19 berlangsung cukup cepat, dan menyebar ke berbagai Kabupaten di Indonesia dalam waktu singkat termasuk Kabupaten Poso. Upaya pencegahan peningkatan jumlah kasus COVID-19 sangat penting utamanya pada level masyarakat. Untuk mencapai hal tersebut salah satunya melalui pemberdayaan masyarakat dengan pembentukkan Desa SARAN COVID-19 yang bertujuan untuk meningkatkan pengetahuan masyarakat tentang pencegahan penularan COVID-19. Desa Masani merupakan salah satu wilayah di Kabupaten Poso yang lokasinya cukup terpencil karena berada di pesisir pantai. Masyarakat Desa Masani belum menggunakan masker saat keluar rumah, penggunaan masker yang belum benar, tidak menjaga jarak serta belum membiasakan untuk cuci tangan. Hal inilah yang menjadi dasar pelaksanaan pengabdian yang bertujuan untuk pemberdayaan masyarakat dengan pembentukkan Desa Cerdas Lawan (SARAN) COVID-19. Pengabdian dilakukan dengan koordinasi dan sosialisasi, pretest, edukasi pencegahan penularan COVID-19, posttest, pembuatan rumah percontohan, pembentukan relawan COVID-19 serta monitoring dan evaluasi. Kegiatan pengabdian dihadiri 60 peserta. Hasil pengabdian menunjukkan 81.6% dengan pengetahuan baik yang sebelumnya 71,6% dengan pengetahuan kurang, terwujudnya pembuatan rumah percontohan pencegahan COVID-19, monitoring evaluasi menunjukkan 70% masyarakat sudah patuh menggunakan masker.Abstract: The increase of COVID-19 cases took place quite quickly, and spread to various districts in Indonesia in a short time including Poso Regency. Efforts to prevent an increase in the number of COVID-19 cases are very important, especially at the community level. To achieve this, one of them is through community empowerment by establishing a COVID-19 SAR Village which aims to increase public knowledge about preventing the transmission of COVID-19. Masani Village is one of the areas in Poso Regency which is quite remote because it is located on the coast. The people of Masani Village have not used masks when leaving the house, have not used masks correctly, have not kept their distance and have not gotten used to washing their hands. This is the basis for implementing community service aimed at empowering the community by establishing a COVID-19 Smart Lawy Village (SARAN). The service is carried out through coordination and socialization, pretest, education on prevention of COVID-19 transmission, posttest, construction of pilot houses, formation of COVID-19 volunteers as well as monitoring and evaluation. The service activity was attended by 60 participants. The results of the service showed 81.6% with good knowledge previously 71.6% with less knowledge, the realization of the creation of a COVID-19 prevention pilot house, evaluation monitoring showed 70% of the community had complied with wearing masks.

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