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All Journal Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Martabe : Jurnal Pengabdian Kepada Masyarakat CARADDE: Jurnal Pengabdian Kepada Masyarakat PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Manuju : Malahayati Nursing Journal JURNAL FARMASI GALENIKA JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Jurnal Mandala Pharmacon Indonesia Majalah Farmasetika Jurnal Darma Agung Reswara: Jurnal Pengabdian Kepada Masyarakat SEMAR Jurnal Pengabdian Kesehatan Vivabio : Jurnal Pengabdian Multidisiplin Proceeding of Mulawarman Pharmaceuticals Conferences ACROPORA: Jurnal Ilmu Kelautan dan Perikanan Papua Jurnal Pengabdian Papua Jurnal Farmasi Sains dan Praktis JURNAL BIOLOGI PAPUA Jurnal Farmasi Indonesia Jurnal Penelitian Sains dan Kesehatan Avicenna Bakti Hayati EBAMUKAI; JURNAL PENGABDIAN ILMU PENGETAHUAN DAN TEKNOLOGI Manfish: Jurnal Ilmiah Perikanan dan Peternakan Jurnal Farmasi Galenika Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

Elsye Gunawan

Universitas Cenderawasih

Author-ID : 2583640

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Title

Aktivitas Antikoagulan dari Tumbuhan Kayu Ular (Strychnos lucida R.Br.) Elsye Gunawan; Aris A.L. Toruan; Rusnaeni Rusnaeni; Felycitae E. Appa
Jurnal Biologi Papua Vol 14, No 2 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

The stem of the snakewood plant (Strychnos lucida) has been used empirically as a malaria drug, relieves fever, treats stomach pain, hemorrhoids, rheumatism, stroke symptoms, and improves blood circulation. Tannins as one of the secondary metabolites of snakewood stems contain gallic acid compounds which are known to thin the blood. The purpose of this study was to determine the anticoagulant activity of the ethanolic extract of snakewood stems on blood group samples, namely A, B, AB, and O. The method used for extraction was maceration, for testing anticoagulants used method modified Lee-White and blood smears, as well as for data analysis carried out descriptively. The results obtained by the Lee-White modification method on blood group samples were visually not clotting. For anticoagulant activity by blood smear method, it was shown that microscopically snakewood bark extract prevented the presence of blood clots which could be observed with unrelated blood cells, intact and separated from each other.Key words: S. lucida; Lee-White modification; blood smear; anticoagulants

Tingkat Kepuasan Pasien Terhadap Pelayanan Kefarmasian di Puskesmas Sentani dan Puskesmas Waena, Provinsi Papua Ega Riana; Elsye Gunawan; Nur F. Bakrie
Jurnal Biologi Papua Vol 14, No 1 (2022)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Patient satisfaction is a level of patient feeling that arises as a result of the performance of health services that their received after compared to the expectation. Pharmaceutical service is a form of direct and responsible service to patients related to pharmaceutical preparations with the aim of achieving definite results to improve the quality of life of patients. This research was conducted at the Sentani Health Center and Waena Health Center in July-August 2020,This study used descriptive survey method, sampling with purposive sampling method. Data will be obtained through questionnaires which distributed to respondents who meet the research inclusion criteria. The results showed that as many as 200 respondents are satisfied with the quality of pharmaceutical services at the Sentani Health Center and the Waena Health Center, for the five consecutive dimensions as follows Reliability with a score of 4.05 and 4.15, Responsiveness with a score of 4.07 and 4.20, Confidence with a score of 4.11 and 4.00, Empathy with a score of 4.07 and 4 .00, and Tangible 4.17 and 4.18, respectively. This means that patients and their families are satisfied with pharmaceutical services at the Sentani and Waena health centers in Jayapura, Papua.Key words: patient satisfaction; pharmaceutical services; Sentani Health Center; Jayapura.

Phytochemical Screening, Antibacterial and Cytotoxic Activity of Dendobium lasianthera J.J.Sm. from Papua Verena Agustini; Eva S. Simaremare; Elsye Gunawan; Jane Awom; Susan Wopi
Jurnal Biologi Papua Vol 12, No 2 (2020)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

The aims of the study are to evaluate bioactive compounds, antibacterial and cytotoxic potential of D. lasianthera. This orchid grows well all over New Guinea Island as an ornamental plant because of their beautiful flowers. Orchids also known rich of its phytochemical compounds which already used as a traditional medicine in many countries around the world. However, research in pharmacological fields is still limited. In this study, leaves and stem of D. lasianthera were powdered and extracted with ethanol followed by fractionated using n-hexane, ethyl acetate, and ethanol solvent. Extract as well as fraction were tested for phytochemical screening and determined antibacterial activity against Escherichia coli and Staphylococcus aureus using Disc Diffusion Method. Brine Shrimp Lethality Test (BSLT) was used to observe cytotoxic potential of leaves and stem extract and fraction at 10, 50, 100, 250, 500, 750, and 1000 ppm. The results showed that the leaves and stem extract contained tannin and alkaloids, separately. The ethanol extract of D. lasianthera showed 7.35 mm (leaves) and 7.43 mm (stem) inhibition zone against S. aureus Furthermore, the maximum inhibition zone of ethanol fraction of leaves and n-hexane fraction of stem were 8.42 mm and 8.10 mm separately. The LC50 of stem extract and fractions in these study were 699.3 ppm (ethanol extract), 602.1 ppm (ethyl acetate), 329.6 ppm (n-hexane fraction) and 676 ppm (ethanol fraction), whereas for leaves, only ethyl acetate fraction has toxict activity with an average LC50 833.2 ppm. Key words: D. lasianthera; phytochemical screening; antibacterial; cytotoxicity; Papua.

Uji Aktivitas Sitotoksik Fraksi Daun Matoa (Pometia pinnata) dengan Metode Brine Shrimp Lethality Test (BSLT) Risma Payung; Elsye Gunawan; Rani D. Pratiwi
Jurnal Biologi Papua Vol 13, No 2 (2021)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Matoa (Pometia pinnata) is parts of Sapindaceae family widely spread in tropical areas, especially in Papua. Several studies mentioned the use of its parts as antioxidants and contain phenolic compounds and flavonoids. This study aim(s) to conduct a phytochemical screening test as well as a cytotoxic test for Pometia pinnata leaves fraction using the BSLT method. The research series began with the extraction process using 96% ethanol, then fractionated using three solvent variations: n-hexane, ethyl acetate, and ethanol. Further, the phytochemical screening test was carried out for cytotoxic testing in order to see the mortality rate of shrimp larvae Artemia salina Leach. The result of the phytochemical showed that the secondary metabolite compounds on the ethanol and ethyl acetate fraction were alkaloids, flavonoids, saponins, tannins, and terpenoids compounds meanwhile the n-hexane fraction contained terpenoids. The results of cytotoxic testing BSLT showed the LC50 value in the n-hexane was 7029.10 ppm, 406.07 ppm for ethyl acetate and 614.47 ppm for ethanol. Thus, it could be said that ethyl acetate and ethanol fractions were classified as a toxic category, while n-hexane was classified as a non-toxic category.Key words: matoa; fraction; phytochemical screening; cytotoxic.

Pengembangan Produk Minuman Tonikum Kulit Kayu Akway (Drymis piperita): Prospek Penambah Stamina Tubuh Secara In Vivo Noviana Hallik; Rani D. Pratiwi; Elsye Gunawan
Jurnal Biologi Papua Vol 13, No 1 (2021)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Akway bark (Drymis piperita) from Papua is widely used by local people in Arfak Mountains of West Papua to increase stamina. The purpose of this study was to determine the physical quality and tonic effects of Akway bark (bark tonic drink D. piperita) on mice (Mus musculus). The swimming resistance used to determine the tonic effect of mice (24 individuals) which divided into 6 groups. Group I was given water, group II tonic drink base, group III as positive control of 50 mg caffeine energy drinks, groups IV, V, and VI were given bark tonic drink 10mg /kg body weight, 30 mg/kg body weight, and 50mg /kg body weight respectively. The total period swimming until fatigue was measured and used as an index of swimming capacity. The results of physical quality of the Akway bark tonic drink has a sweet and sour taste, with clear dark brown color, had distinctive aroma with pH of 4, and its volume was 100 ml with solubility deposits on day 21. The results of pre-clinical testing shown the highest dose was 50 mg/ weight swimming time 9.28 minutes and having better stamina. The next was with dose of 30 mg/kgBW, swimming for for 6.01 minutes and the last was dose of 10 mg /kgBW swimming for 3.23 minutes. The results of the one-way ANOVA test showed that it was significantly different between the 10 mg/kgBW, 30 mg/kgBW and 50 mg/kgBW groups. Key words: drink; D. piperita tonic; effect; mice; Papua.

Evaluasi Penggunaan Obat Antimalaria di Rumah Sakit Umum Daerah (RSUD) Abepura, Jayapura Deshinta S. Natalia; Elsye Gunawan; Rani D. Pratiwi
Jurnal Biologi Papua Vol 8, No 2 (2016)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Evaluation of drug use is a quality assurance process that is carried out continuously, organizational structured and recognized to ensure that the drug is used appropriately and effectively. Until recently, Jayapura city is still as a malarial endemic area. In 2012, the number of malaria cases are malarial tertiana 8.535 (39%) cases, malarial tropical 12.256 (57%), malarial mix (tertiana+tropical) 612 (2,84%) and malarial quartana 73 (0,33%). The highest percentage of malarial cases in the Jayapura city is caused by Plasmodium falciparum. The aims of this study are to evaluate the drug use and the dose accuracy of antimalarial drugs in the General Hospital of Abepura from July to December 2014. This is a descriptive study conducted by a retrospective review of medical records of patients. The results of the study concluded that the highest incidence rates occurred in the male (59.04%) and lowest in women (40.96%), 15-25 years of age (57.8%), 26-35 years of age (27.7%) and 36-45 years of age (14.5%). The dose accuracy for antimalarial drugs (100%) indicated that antimalarial drugs used are Primaquine, Artesunate injection and Dihydroartemisin + piperaquine (DHP) or Darplex. Key words: Abepura hospital, antimalarial drug, Jayapura, malaria

Potensi Ekstrak Etanol Kulit Batang Jabon (Anthocephalus cadamba (Roxb) Miq.) Sebagai Antiinflamasi Bakri, Nur F.; Rusnaeni; Sasarari, Sarce M.; Gunawan, Elsye
Jurnal Biologi Papua Vol 16 No 1 (2024)
Publisher : Jurusan Biologi FMIPA Universitas Cenderawasih

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31957/jbp.3362

This study investigates the anti-inflammatory properties of an ethanol extract from Jabon plant stem bark in male mice using the Rat Hind Paw Edema method. Twenty-five male mice were divided into five groups: negative control (Na-CMC 1%), positive control (mefenamic acid), and three groups receiving the extract at doses of 50 mg/kg, 100 mg/kg, and 200 mg/kg. Measurements were taken every 30 minutes for three hours using a plethysmometer. Analysis with one-way ANOVA and Duncan's test revealed significant anti-inflammatory effects for all doses, with the most effective being 100 mg/kg, showing 93.42% inhibition. The results suggest Jabon plant extract as a promising anti-inflammatory agent.

Co-Authors Agustina Ruban Akrom, Akrom Allowisya Futwembun Andre Anusta Barus Andre M. Worabai Anisa Nurhidayah Aris A.L. Toruan Aurina Megawati Numberi Awuy, Jessy Alfritha Bakri, Nur F. Basmindah Basmindah Cakranegara, Pandu Adi Claudius Hendraman B. Tobi D. Pratiwi, Rani de Fretes, Christina Deshinta S. Natalia Desky Kondolele Dimas A. Syafrudin Dina Ayomi Dominggus Kalor, John Dyah A. Perwitasari Ega Riana Eka Febri Rahmawati Elfride Irawati, Elfride Elizabeth Hole Elizabeth Hole Enjeline Siregar Erianus Uopmbin Fadhilah, Nabila Nur Fadil M. Al Ridha Fadilah Bakrie, Nur Fadilla, Izmaya Nur Febrianty, Silva Dewi Febriyanti, Christine Felycitae Ekalaya Appa G. Kendenan, Bryan Gerson Andrew Warnares Hasnawati Irene Sondang Lingga J. S. Sipahelut, Vrysel Jane Awom Jessy Alfritha Awuy John Dominggus Kalor John Dominggus Kalor John Dominggus Kalor, John Dominggus Juniarto Mende Karlin Mansumber Khoirul Huda Komar Ruslan Wirasutisna Krisna Dewi Krisna Dewi Krisna Dewi, Krisna Kristina I. Rahail Lia Rahmadiyani Yustina Manemi, Putri Winduri Marselina E. Koten Maulana, Yusuf Eka Megawati Samosir, Sylvia Muhammad M. Khalil Muhammad Munawar Khalil Mustika Endah Pratiwi N. Kurnia, Indah Noviana Hallik Nur F. Bakrie Nur Fadilah Bakri Ota M. Rumainum Parandan, Ronald Perwitasari, Dyah A. Pitera Wenda Qonita A. Nisa R. Reniurwarin, Sulis Rani D. Pratiwi Rani D. Pratiwi Rani D. Pratiwi Rani Dewi Pratiwi Risma Payung Rizka Agustine Rosye H.R. Tanjung Ruban, Agustina Rusnaeni Rusnaeni Rusnaeni Rusnaeni Rusnaeni Ruth Yabansabra, Yuliana S. Lingga, Irene Sarhana R.A. Said Sarhana Sarhana Rassya Aulyah Said Sasarari, Sarce M. Sawaki, Yuliana Simaremare, Eva Sitti Khairul Bariyyah Soltief, Sitti Nurdjaja Surbakti, Kevin Susan Wopi Suthelie, Chinry Charolina T. R. Setyoningrum, Retno Tahamata, Yefani Tatang Sutarman Ulva, Dea A. Valerie Palege Verena Agustini Verena Agustini Yabansabra, Yuliana Ruth Yabansabra, Yuliana Y. Yuli Astuti Yuliana R. Yabansabra Yuliana Ruth Yabansabra Yuliana Sawaki Yuliana Y. Yabansabra

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