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Wulansari, Silvi ayu
Akademi Farmasi Surabaya
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Antibacterial Activity of Vesicularia ferriei Ethanol Extract Againts Staphylococcus aureus: Aktivitas Antibakteri Ekstrak Etanol Lumut Vesicularia ferriei Terhadap Bakteri Staphylococcus aureus Andhika Dwi Aristyawan; Umarudin; Mercyska Suryandari; Silvi Ayu Wulansari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 2 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i2.552

Abstract

Indonesia's tropical climate contributes to a high incidence of bacterial infections, including those caused by Staphylococcus aureus. This Gram-positive bacterium forms irregular clusters, does not produce spores, is facultatively anaerobic, and is immobile. It is responsible for various infections, including skin infections, endocarditis, bacteremia, and pneumonia. Vesicularia ferriei, an aquarium moss commonly used in aquascaping, belongs to the Hypnaceae family and contains secondary metabolites such as flavonoids, flavonols, and triterpenoids. This study aims to determine the antibacterial activity of Vesicularia ferriei ethanol extract against Staphylococcus aureus. The antibacterial activity was tested using the disc diffusion method with the pour plate technique at concentrations of 100 ppm, 500 ppm, 1,000 ppm, 5,000 ppm, and 10,000 ppm, with three replications. The results showed weak inhibition zones around the paper discs at 5,000 ppm (3.76 mm) and 10,000 ppm (4.76 mm). The negative control (10% DMSO) produced no inhibition zone, while the positive control (Cefadroxil antibiotic) exhibited a strong inhibition zone averaging (15.07 mm). These findings indicate that the ethanol extract of Vesicularia ferriei has antibacterial activity against Staphylococcus aureus, albeit in the weak category. This study serves as a reference for further research exploring different extraction methods, antibacterial testing techniques, solvents, and extract concentrations. Additional studies are needed to investigate the broader benefits of Vesicularia ferriei extract and its potential as an antibacterial agent.
Effect of Mixing Duration on Lip Cream Formulated with Caesalpinia sappan and Hibiscus sabdariffa Extracts : Pengaruh Lama Pengadukan Lip cream Kombinasi Ekstrak Kayu Secang (Caesalpinia sappan L.) Bunga Rosella (Hibiscus sabdariffa L.) Eliza Stepanie Romadhona; Eka Otaviani Aisyah; Fitria Abbas Thalib; Silvi Ayu Wulansari; Tri Puji Lestari Sudarwati
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 11 No. 2 (2026): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v11i2.584

Abstract

Lip cosmetics, particularly lip creams, are highly sought after for their texture and natural colors. However, many commercial lip creams still use synthetic dyes, which can cause irritation or toxicity. Natural dyes from plants are a safer alternative. This study used extracts of sappanwood (Caesalpinia sappan), which contains brazilin, and roselle flowers (Hibiscus sabdariffa), which contain anthocyanins. This study aims to determine the effect of stirring time on the physical characteristics of lip cream containing a combination of sappan wood extract (Caesalpinia sappan L.) and rosella flower extract (Hibiscus sabdariffa L.). This research is an experimental study using three variations of stirring time: 10, 20, and 30 minutes. Evaluations were carried out on organoleptic, homogeneity, pH, spreadability, and hedonic tests. The organoleptic test showed uniformity of color, aroma, and texture. The homogeneity test gave homogeneous results.The research results indicate that a stirring duration of 30 minutes yields a lip cream with a more stable pHand higher spreadability compared to durations of 10 and 20 minutes.
Co-Authors Aisyah Hadi Ramadani Anidnya, Widya Dara Anindya, Widya Dara Aristyawan, Andhika Dwi Aryani, Ni Luh Dewi Azka Nur Khoirun Bawanda, Edward Melfin Denis Alifia Azzahro Devianti, Vika Ayu Eka Otaviani Aisyah Eliza Stepanie Romadhona Evy Aryanti Eziah Ika Lubada Fatma Ariska Trisnawati Fitria Abbas Thalib Galuh Gondo Kusumo Kinanti Ayu Puji Lestari Kinanti Lestari Lailatus Sa'diyah Lailatus Sadiyah Lailatus Sa’diyah Lamtiur Nainggolan Mercyska Suryandari Permatasari, Silfiana Nisa Ramadhan Renaisansa Ramadhan Renaisansa Ririn Sumiyani Romadhona, Eliza Stepani Sa'diyah, Lailatus Sa’diyah, Lailatus Sa’diyah, Lailatus Selvyronica Eka Agustine Siti Nurhaliza Soraya Isvandaria Devie Surahmaida, Surahmaida Syukrianto Syukrianto, Syukrianto Tri Puji Lestari Sudarwati Ulfa, Ninik Mas Umarudin, Umarudin Yuliarni, Floreta Fiska