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All Journal Farmaka Pelita Masyarakat Edu Masda Journal Edu Dharma Journal: Jurnal penelitian dan pengabdian masyarakat INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Assyifa: Jurnal Ilmu Kesehatan Lhokseumawe Jurnal Medical Laboratory IJESPG (International Journal of Engineering, Economic, Social Politic and Government) journal Madani: Multidisciplinary Scientific Journal Detector: Jurnal Inovasi Riset Ilmu Kesehatan Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Kesehatan dan Kedokteran Jurnal Sains dan Kesehatan Darussalam Jurnal Medika Farmaka Pharmaceutical Science Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Pharma Bhakta Jurnal Kefarmasian Indonesia Jurnal Sains & Kesehatan Darussalam JOURNAL OF Pharmacy and Tropical Issues
Firdha Senja Maelaningsih
STIKes Widya Dharma Husada Tangerang
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Review Artikel : Analisis Kandungan Fluoride dalam Pasta Gigi dengan Metode Potensiometri dan Elektroda Selektif Ion Syuhriah Syuhriah; Laelatun Nupus; Fadiya Qotrunnada; Firdha Senja Maelaningsih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.899

Abstract

Toothpaste is an essential product for maintaining dental health, where fluoride is one of the key components commonly added. Fluoride plays a crucial role in strengthening enamel and preventing cavities, but the fluoride content in toothpaste must be adjusted according to age groups to avoid the risk of fluorosis, especially in children The literature review aims to evaluate the fluoride content in toothpaste analyzed using potentiometric methods with fluoride ion-selective electrodes (F-ISE). Through a literature review of five research articles published from 2014 to 2024, significant variations in fluoride levels were found. Some products met WHO standards (1000–1500 ppm), while others did not meet criteria, having either too low or too high fluoride content. The potentiometric method proved to be accurate and reliable; however, stricter supervision and regulations are needed to ensure product safety. In conclusion, it is important for consumers to understand the fluoride levels in the toothpaste they use and to ensure the selection of safe and effective products.
POTENSI HYDROGEL LIMBAH KULIT PISANG KEPOK (MUSA PARADISIACA L.) SEBAGAI PENYEMBUHAN LUKA SECARA IN VIVO PADA MENCIT GALUR SWISS WEBSTER Sari, Diah Permata; Evani, Azmi Zauli; Sopian, Ahmad; Maelaningsih, Firdha Senja; UZ, LM Zulfahrin; Nurihardiyanti, Nurihardiyanti; Fauziah, Vina
Edu Masda Journal Vol 9, No 2 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i2.292

Abstract

                                                  ABSTRACTThe use of kepok banana peel as a traditional medicine can be an alternative for people to further develop the use of traditional medicine, one of which is as a wound healing ingredient. The purpose of this study was to formulate hydrogel preparations from kepok banana peel extract (Musa paradisiaca L) with various concentrations as an effort in developing preparations for healing open wounds. The research method used was experimental, namely evaluation of hydrogel preparations and in vivo wound closure tests on Swiss Webster mice. The results of hydrogel tests with 3 formulas obtained that F1 HG-EKPK 2.5%, F2 HG-EKPK 5% and F3 HG-EKPK 7.5%, resulted in no physical problems in the organoleptic test, although in the evaluation of homogeneity, pH, spreadability, adhesiveness and viscosity there was instability in concentration. Based on the results of the In Vivo test, it was found that the administration of hydrogel preparations at F1 HG-EKPK 2.5%, F2 HG-EKPK 5%, F3 HG-EKPK 7.5% showed optimal wound closure when compared with the negative control                                                      ABSTRAKPemanfaatan kulit pisang kepok sebagai obat tradisional dapat menjadi alternatif bagi masyarakat untuk lebih mengembangkan penggunaan obat tradisional, salah satunya sebagai bahan penyembuhan luka. Tujuan dari penelitian ini adalah untuk memformulasikan sediaan hidrogel dari ekstrak kulit pisang kepok (Musa paradisiaca L)dengan berbagai konsentrasi sebagai upaya dalam pengembangan sediaan sebagai penyembuhan luka terbuka. Metode penelitian yang digunakan adalah eksperimental yakni evaluasi sediaan hydrogel dan uji penutupan luka secara in vivo pada mencit galur swiss webster. Hasil uji hidrogel dengan 3 formula didapatkan bahwa F1 HG-EKPK 2,5%, F2 HG-EKPK 5% dan F3 HG-EKPK 7.5%, menghasilkan pada uji organoleptis tidak terdapat permasalahan secara fisik, meskipun pada evaluasi homogenitas, pH, daya sebar, daya lekat dan juga viskositas terdapat ketidak stabilan pada sediaan. Berdasarkan hasil uji In Vivo pada mencit diketahui bahwa pemberian sediaan hidrogel pada F1 HG-EKPK 2,5%, F2 HG-EKPK 5%, F3 HG-EKPK 7.5% menunjukan penutupan luka optimal jika dibandingkan dengan kontrol negatif.
The Characterization of Instant Granule Melinjo Peel (Gnetum gnemon Linn.) as Alternative Treatment for Hyperuricemia Maelaningsih, Firdha Senja; Sari, Diah Permata; Fahriati, Andriyani Rahmah; Saputra, Teungku Raviola; Ansori, Andika Al
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hyperuricemia is a non-communicable disease characterized by high levels of purine in the blood. One of the foods high in purine is melinjo chips. Instant granules from melinjo peel extract with a concentration of 450 mg have been proven to be effective as an anti-hyperuricemia treatment. To ensure the quality of the instant granule preparation, a quality evaluation was conducted to establish it as a new alternative in hyperuricemia therapy. The study aimed to assess the quality of the instant granule preparation of melinjo peel extract, including physical evaluation (particle size, loss on drying, and pH), characterization with Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR), and specific microbial tests. The test results revealed that the particle size of the instant granules was classified as coarse particles, the Loss on Drying results showed 1.29% granule loss, and the pH evaluation indicated that the granules had a pH of 7.78. Based on the SEM characterization, the granules exhibited non-clumping and heterogeneous morphology. FTIR analysis showed the presence of quercetin in the instant granules of melinjo peel. Specific microbial testing indicated the absence of E. Coli in the preparation. Therefore, it is concluded that the instant granule preparation of melinjo peel has characteristics that make it suitable for development as an instant nutraceutical granule preparation for anti-hyperuricemia treatment.
Co-Authors Abdillah Abdillah Adelia Rahmawati Ahmad Sopian, Ahmad Airani, Rahma Arla Airin, Ivo Ovia Akhmad Sobarudin Aledea Safitri Aliya Nur Hasanah Amartyavica Asta Ginasih Amelia, Ditha Andina, Cantika Andriyani Rahmah Fahriati Anggel Imelda Ranboki Anis Dwi Kristiyowati Anjeli Rahmawati Ansori, Andika Al Assyifa Rachma Citra Aurli Fitria Ayu Werawati Azizah Nurma Qurotul ‘Aini Azzahra, Fathia Beny Maulana Satria Bheta Sari Dewi Cahyani, Lufitha Evelyne Chasanah, Eneng Uswatun Dara, Nabila Dea Ayu Anggraeni, Dea Ayu Anggraeni Denisa, Dila Dewi Astuti, Mardyana Dhea Mutiara Diah Permata Sari DIAH PERMATA SARI, DIAH PERMATA Dimas Agung Waskito Wijanarko Dinah Suwaybatul Aslamiyah Dinda Yuliantika Elena Prida Elza Tiani Lestari Evani, Azmi Zauli Fadiya Qotrunnada Fajrin, Aulia Farah Aulia Qatrunnada A Farhan Aziz, Muhammad Febriyanti, Nabila Fenita Purnama Sari Indah Frederico, Frederico Fu'adah, Intan Tsamrotul Gandes Winarni Getrudis Anita Seran Hapsari, Maretha Vien Helina Hermat Hermat Hersa, Mutiara Hidayatri, Nurul Humaira Fadhilah Ihsani, Salfia Ika Andini Ika Elvina Rahmawati Indiarti Ayu Silvia Ismiati, Hastin Kristiyowati, Anis Dwi Laelatun Nupus Larasati Larasati Larasati, Fannisa Dini Lestari, Bilqisti Rahmadani Lilik Febriyani Linawati Linawati Lisna Sari Luciana Luciana Mokodompit, Nurhaliza Martasya Muhamad Kholilu Navis Muhammad Ikhsanul Kahfi Muzaqil, Firmansyah Nabila N Nadia Shinta Purnomo Nanang Yunarto Nazila Khoerunnisa Novita Sary Nur Hasanah Nurhakiki, Nurhakiki Nurida Nurihardiyanti Nurihardiyanti, Nurihardiyanti Nurohmah, Alivia Octaviela, Tyara Oktaviani, Livia Ovia Airin, Ivo Pomalingo, Dwina Ramadhani Putri Nur Auliya Rahman Putri Sartika Rahma Shalsadilla Rahmalia, Rahmalia RIRIS ANDRIATI Rismiyanti, Aina Sahara, Khalipatun Sahira Madliya, Juliettania Salsabila, Fannysa Saputra, Teungku Raviola Saputri, Laras Tri Saputri, Safira Nurul Islam Sayyidah Sayyidah Sayyidah, Sayyidah Selvi Ramadani Silfiana, Ayu Sirait, Sertiwan Siti Chodijah Siti Fauziah Ahmad Suny Koswara Rahajeng SUSANTI Susanti Susanti Syuhriah Syuhriah Tiara Fitri Anggraeni Utami, Anissa UZ, LM Zulfahrin Vien Hapsari, Maretha Vina Fauziah Yollanda, Ade Yuhareza Aulia Eka Putri, Yuhareza Aulia Eka Putri Yulianingrum, Mutiara Yunita Yunita Zulfahrin, LM