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All Journal Farmaka Pelita Masyarakat Edu Masda Journal Edu Dharma Journal: Jurnal penelitian dan pengabdian masyarakat INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Jurnal Assyifa: Jurnal Ilmu Kesehatan Lhokseumawe Jurnal Medical Laboratory IJESPG (International Journal of Engineering, Economic, Social Politic and Government) journal Madani: Multidisciplinary Scientific Journal Detector: Jurnal Inovasi Riset Ilmu Kesehatan Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Kesehatan dan Kedokteran Jurnal Sains dan Kesehatan Darussalam Jurnal Medika Farmaka Pharmaceutical Science Journal Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Pharma Bhakta Jurnal Kefarmasian Indonesia Jurnal Sains & Kesehatan Darussalam JOURNAL OF Pharmacy and Tropical Issues
Firdha Senja Maelaningsih
STIKes Widya Dharma Husada Tangerang
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Review: Analisis Kandungan Logam Berat Timbal Pada Sediaan Bedak Dalam Negeri dan Internasional Menggunakan Metode Spektrofotometri Serapan Atom Rismiyanti, Aina; Azzahra, Fathia; Chodijah, Siti; Maelaningsih, Firdha Senja
Madani: Jurnal Ilmiah Multidisiplin Vol 1, No 12 (2024): Madani, Vol. 1 No. 12 2024
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10421283

Abstract

In this era, the use of cosmetic products in Indonesia has increased significantly. One of the most popular cosmetic products is powder, which contains heavy metals, especially lead, as a colorant. By the provisions of BPOM RI in 2014, the maximum limit of lead heavy metal contamination in cosmetics, including powder, should not exceed 20 mg/kg. As well to the US FDA, which stipulates that the value of lead as an impurity in cosmetic products should not exceed 20 mg/kg. The purpose of this journal review is to assess the levels of lead metal in cosmetic products, especially powder, circulating in various regions in Indonesia and several countries. The literature study method uses secondary data obtained from the Google Scholar database for the last 10 years. 8 articles were found that met the inclusion and exclusion criteria, could be accessed in full text, and had an ISSN number for review. The overall results of the journal review regarding the analysis of heavy metal content, especially lead, were carried out by analyzing solid powder preparations and powders according to atomic absorption spectroscopy (SSA) procedures, which resulted in research-based data.
Review: Analisis Kandungan Klorin dan Formaldehid Pada Pembalut Wanita Larasati, Fannisa Dini; Saputri, Safira Nurul Islam; Yollanda, Ade; Maelaningsih, Firdha Senja
Madani: Jurnal Ilmiah Multidisiplin Vol 1, No 12 (2024): Madani, Vol. 1 No. 12 2024
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.10432577

Abstract

Sanitary napkins are a medical device used during menstruation to absorb menstrual blood. Sanitary napkins are a product that uses chlorine as one of the ingredients, which can be used to clean sanitary napkins so they are always white (bleach). Apart from chlorine, formaldehyde can also be added to sanitary napkins to act as an anti-wetting agent and preservative. This research aims to discuss various studies related to the analysis of chlorine and formaldehyde content in sanitary napkins. This research analyzes the literature available in journals published in the last 10 years via Google Scholar. Chlorine analysis uses the iodometric titration, iodometric titration, argentometric titration, and UV-vis spectrophotometry methods. Meanwhile, formaldehyde analysis uses UV-vis spectrophotometry. The results of various studies show variations in the chlorine and formaldehyde content of the sanitary napkin samples tested.
Formulation of Instant Granules from Ethanolic Extract of Melinjo Peel (Gnetum gnemon L) Extract as Anti-Hyperuricemia Sari, Diah Permata; Fahriati, Andriyani Rahmah; Maelaningsih, Firdha Senja
Jurnal Kefarmasian Indonesia VOLUME 13, NUMBER 2, AUGUST 2023
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v13i2.6290

Abstract

Melinjo (Gnetum gnemon L) is extensively found in Indonesia, and all of its components are highly employed, with the fruit being the most commonly used. However, melinjo fruit can induce hyperuricemia if ingested excessively since it contains purines, which can raise uric acid levels. Several investigations have found that melinjo peel can lower uric acid levels in experimental rats in vivo. As a result, the goal of this study is to create and evaluate immediate granule formulations of melinjo peel extract. Plant determination, standardization of specified parameters, standardization of non-specific parameters, formulation, and physical and chemical assessment of instant granules of melinjo peel extract are all steps of the technique. This study employed two instant granule formulations of melinjo peel extract FI and FII with varying PVP concentrations (1g FI and 3g FII). Flow time testing, angle of repose testing, compressibility index testing, water content testing, and dissolving time testing were all part of the physical examination of instant granules. The chemical evaluation took the form of a UV-Vis spectrophotometer study of total flavonoid levels in instant extracts and granules. The FI and FII instant granule formulas had a yellow color, the flow time test results were in a good category (44 g/s and 81 g/s), the angle of repose test results was in the very good flow properties category (19° and 16°), the compressibility test results, the water content test, and the dissolving time test were performed in triplo, in 0, 7th, and 14th day, and the results were in a good category. In conclusion, the physical features of instant granules of FI and FII melinjo peel extracts fulfilled the requirements for all test parameters and had a high possibility to be produced as anti hyperuricemia preparations.
ANALISIS BAHAN KIMIA OBAT FENILBUTAZON DALAM SEDIAAN JAMU PEGAL LINU DENGAN METODE KROMATOGRAFI LAPIS TIPIS : LITERATUR REVIEW Amartyavica Asta Ginasih; Anjeli Rahmawati; Ika Andini; Firdha Senja Maelaningsih
Journal of Science and Health Darussalam Vol. 3 No. 2 (2023): Jurnal Sains dan Kesehatan Darussalam
Publisher : Akademi Analis Farmasi dan Makanan Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56690/jskd.v3i2.98

Abstract

Kromatografi lapis tipis merupakan salah satu metode pengujian yang digunakan untuk menganalisis bahan kimia obat (BKO) dalam sediaan jamu tradisional. Penggunaan BKO pada jamu sangat berbahaya bagi kesehatan karena umumnya jamu dikonsumsi dalam jangka waktu yang lama. Apabila jamu yang dikonsumsi tersebut mengandung BKO maka akan memberikan banyak kerugian bagi yang mengonsumsinya. Berdasarkan beberapa kasus penggunaan BKO pada jamu untuk pegal dan linu yang telah disampaikan oleh Badan Pengawas Obat dan Makanan (BPOM), BKO yang paling banyak ditemukan yaitu fenilbutazon. Literatur review ini bertujuan untuk memberikan informasi, mengkaji serta menjelaskan cara mengidentifikasi salah satu BKO fenilbutazon yang terkandung dalam suatu sediaan jamu pegal linu dengan metode kromatografi lapis tipis. Metode yang digunakan pada literatur review ini yaitu dengan meninjau 10 artikel ilmiah yang diterbitkan dalam kurun waktu 2013 - 2023 yang berisi tentang informasi terkait kandungan bahan kimia obat di dalam sediaan jamu tradisional serta metode pengujian kualitatif. Berdasarkan literatur review ini diketahui 18 sampel positif mengandung fenilbutazon dan terdapat berbagai fase gerak yang dapat digunakan dalam analisis fenilbutazon pada jamu pegal linu, fase gerak yang sering digunakan yaitu etil asetat : metanol : amonia (85:10:5) sedangkan seluruh literatur menggunakan fase diam yang sama yaitu silika GF254 dan keberhasilan dari analisis fenilbutazon dengan metode kromatografi lapis tipis dapat dilihat dari nilai rf yang dihasilkan identik dengan standar fenilbutazon.
FORMULASI SEDIAAN OBAT KUMUR EKSTRAK DAUN JARAK PAGAR (Jatropa curcus L) DENGAN KOMBINASI PENAMBAH PERASAN JERUK NIPIS (Citrus aurantifolis) SEBAGAI OBAT KUMUR ALAMI sayyidah, sayyidah; Satria, Beny Maulana; Hasanah, Nur; Maelaningsih, Firdha Senja; Kristiyowati, Anis Dwi; dewi, Bheta sari; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.815

Abstract

*Corresponding Author SayyidahE-mail: sayyidah@wdh.ac.id Bad breath is a symptom of an unnoticed disorder or disease. However, sufferers have unpleasant bad breath that arises from the oral cavity. According to Regional Health Research (Riskesdes) in 2013 in the city of South Tangerang, dental and oral health problems increased from 2007 by 19.9% to 2014 by 34.2%, dental and oral problems in children aged 10-14 years were 20, 6%. Jatropha leaf extract can be formulated as a natural mouthwash. Mouthwash is one of the mouth preparations widely available on the market which can be used to treat bad breath, one of the causes of bad breath is the bacteria Candida albicans. Jatropha curcus (Jatropha curcus L) leaves are able to inhibit Candida albicans bacteria that cause bad breath. Lime also contains flavonoids which play a very important role in inhibiting bacterial growth. The aim of this research is to obtain the best physical preparation formula and to determine the evaluation of a mouthwash made from jatropha leaf extract (Jatropa curcus L) with a combination of lime juice (citus aurantifolia) as a natural mouthwash. The formulation of this preparation is made with variations of lime juice in FI (5%), FII (10%), and FIII (15%). The formulation of jatropha leaf extract mouthwash (Jatropha curcus L) was evaluated by physical tests including organoleptic, pH, clarity and viscosity tests. Jatropha curcus (Jatropha curcus L) mouthwash preparation meets pH, viscosity and organoleptic requirements. From the results of the research I conducted, the best preparation was FIII which had a glycerin concentration (15%) and then had a pH value at week 0: 5.91, week 1: 5.07, week 2: 5 .05 and has a viscosity value of 6.90 Cp, which means this viscosity meets the requirements, while the claritytest results obtained did not produce a clear formulation because the color of the Jatropha leafextract is dark green, so it affects the clarity of the formulation.
Artikel : Analisis Drug Related Problems Pada Pasien Tuberkulosis Paru Rawat Inap Di Rumah Sakit Umum Kota Tangerang Selatan Winarni, Gandes; Fajrin, Aulia; Maelaningsih, Firdha Senja; Hidayatri, Nurul
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.899

Abstract

Tuberkulosis merupakan penyakit menular yang disebabkan oleh infeksi basil Mycobacterium tuberculosis. Tuberkulosis merupakan salah satu dari 10 penyebab kematian terbesar di dunia dan penyebab kematian akibat agen infeksi. Pada tahun 2022, diperkirakan 10,6 juta orang terinfeksi penyakit tuberkulosis di seluruh dunia dan jumlah kematian mencapai 1,13 juta orang. Tuberkulosis memerlukan banyak penggunaan obat dalam terapi, semakin banyak penggunaan obat dalam terapi (polifarmasi), semakin tinggi risiko munculnya masalah terkait obat atau Drug Related Problems (DRPs) dalam proses pengobatan. Terjadinya DRPs dapat mengakibatkan terjadinya penurunan kualitas hidup pasien, lamanya tingkat perawatan pasien pada rawat inap di rumah sakit, meningkatnya biaya pengobatan, serta dapat meningkatkan angka kesakitan dan kematian. Tujuan penelitian ini adalah untuk melakukan analisis kejadian DRPs pada pasien tuberkulosis paru di instalasi rawat inap Rumah Sakit Umum Kota Tangerang Selatan tahun 2023. Metode penelitian ini adalah metode deskriptif menggunakan desain penelitian cross sectional dengan jenis penelitian kuantitatif dan data diambil secara retrospektif. Hasil penelitian menunjukkan analisis DRPs dari 81 pasien yang menderita TB Paru ditemukan 67 (85,90%) mengalami DRPs domain C1.3, domain P1.3(10,26%), domain C1.2(1,28%), dan domain C3.1 (2,56%). Kesimpulan dari penelitian ini diketahui karakteristik demografi pasien terbanyak meliputi jenis kelamin laki-laki 53 (65,43%) dan usia 19-29 tahun (30,86%). Adapun DRPs yang dominan terjadi, yaitu domain C1.3 sebanyak 67 kasus (85,90%)
Artikel Review: Metode Analisis Kuantitatif Bahan Merkuri (Hg) dalam Produk Pemutih Kulit (Body Lotion) menggunakan Spektrofotometri Serapan Atom (SSA) di Indonesia Andina, Cantika; Salsabila, Fannysa; Muzaqil, Firmansyah; Senja Maelaningsih, Firdha
Jurnal Medika Farmaka Vol 2 No 3 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i3.40

Abstract

Introduction: Heavy metal mercury is often used in cosmetic products such as body lotion to help speed up the skin whitening process. Cosmetics containing mercury can cause side effects such as skin disorders, cancer, and nervous system poisoning. The purpose of this study is to provide information to readers about research that analyzes mercury content in body lotion products using Atomic Absorption Spectrophotometry (AAS) in several regions of Indonesia. Method: This research method is a literature study involving online article searches from 2014 to 2024 in the Google Scholar database. Results: The results of five article reviews showed the presence of mercury in body lotion product samples. Conclusion: in several regions of Indonesia mercury with the highest concentration of 39.51 mg/kg in Mataram and the lowest 0.051 ppb in Banda Aceh. The majority of products identified as positive do not have a permit from BPOM and are sold freely in the market or online. Therefore, strict supervision of the distribution of cosmetics is needed to protect the public from health risks caused by mercury (Hg). Keywords: Quantitative analysis, body lotion, mercury, atomic absorption spectrophotometry (AAS)
Artikel Review: Analisis Kadar Klorin pada Pembalut dengan Metode Volumetri Sahara, Khalipatun; Nurohmah, Alivia; Maelaningsih, Firdha Senja; Cahyani, Lufitha Evelyne
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.16

Abstract

Introduction: Sanitary napkins are a hygiene product that women very commonly use during menstruation. The safety and quality of sanitary napkins are essential to prevent adverse impacts on health. One crucial aspect that needs to be considered is the level of chemical pollution, such as chlorine, which has the potential to endanger health. The volumetric method is one of the most commonly used methods to measure the chlorine content in various products. In this article, the volumetric method for analyzing chlorine content in sanitary napkins consists of three methods: iodometric titration, iodometric titration, and argentometric titration. This article aims to summarize a literature review that discusses various studies regarding the analysis of chlorine levels in sanitary napkins using the volumetric method. Method: The method used in the article review is a literature review by taking journal articles containing analysis of chlorine levels in sanitary napkins using the volumetric method. Results: A review of various studies showed variations in chlorine levels in the sanitary napkin samples tested. Conclusion: Chlorine levels in sanitary napkins can be analyzed using the volumetric method, with the chlorine results that can be analyzed being in the range of 0.0022% w/v-0.0022% w/v.
Review Jurnal: Aktivitas Deodorant Spray Ekstrak Herbal Pada Bakteri Staphylococcus sp dengan Metode Difusi Agar Sahira Madliya, Juliettania; Rahmawati, Adelia; Ihsani, Salfia; Maelaningsih, Firdha Senja
Jurnal Medika Farmaka Vol 1 No 3 (2023): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v1i3.19

Abstract

Introduction: Body odor is induced by the secretion of sweat glands and bacterial activity. One way to overcome body odor is by maintaining proper body hygiene and using topical preparations such as antiperspirants and deodorants. This study aims to review several journal articles regarding herbal deodorant spray formulations against Staphylococcus bacteria based on the active compound concentration. The literature review was conducted by searching scientific articles published in the last 10 years from 2013 to 2023 using scientific databases. Methods: Several formulation methods have been identified in the reviewed articles including disc diffusion, paper disc diffusion, and agar diffusion methods. The active compounds tested were “kemangi” leaf extract, orange peel extract, and red ginger extract. Results: Showed that increasing the concentration of the active compounds was generally proportional to the increase in antibacterial activity. The optimal concentrations giving good antibacterial activity were 15% for orange peel extract, 8% for “kemangi” leaf extract, and 80% for red ginger extract. Conslusion: This review concludes that herbal extracts have the potential to develop as natural deodorant ingredients and the concentration of active compounds strongly influences the antibacterial activity. Keywords: Herbal extract, Concentration, Antibacterial activity, Test method, Positive and negative controls.
Review Artikel: Identifikasi Bahan Pemanis Buatan Sakarin dan Siklamat Pada Makanan Menggunakan Berbagai Metode Lestari, Bilqisti Rahmadani; Mokodompit, Nurhaliza Martasya; Airani, Rahma Arla; Senja Maelaningsih, Firdha
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 1 (2025): February
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Dalam penggunanya memastikan bahan pemanis harus diperiksa agar kadarnya tidak melewati batas yang ditentukan sebelum ditambahkan ke dalam makanan. Kemajuan teknik analisis kualitatif dan kuantitatif dalam penerapannya sebagai prosedur pengujian bahan tambahan pangan seperti pemanis, dikaji dalam wawasan artikel jurnal. Review artikel jurnal ini bertujuan untuk menganalisis kandungan pemanis pada makanan dengan mengumpulkan dan memancarkan data dari berbagai jurnal yang sesuai. Jurnal dan publikasi ilmiah yang diterbitkan dalam delapan tahun terakhir, dari 2016 hingga 2024, memenuhi persyaratan untuk observasi penelitian ini. Menurut data, produsen makanan sering menggunakan bahan tambahan gula dalam proporsi yang berbeda-beda. Selain itu, ditemukan bahwa metode yang berbeda digunakan untuk menganalisis pemanis buatan. Salah satu kemajuan terbaru dalam metode pemanis analisis adalah metode uji pengendapan, yang memungkinkan untuk mengidentifikasi keberadaan siklamat dalam sampel hanya dengan melihat pembentukan endapan.
Co-Authors Abdillah Abdillah Adelia Rahmawati Ahmad Sopian, Ahmad Airani, Rahma Arla Airin, Ivo Ovia Akhmad Sobarudin Aledea Safitri Aliya Nur Hasanah Amartyavica Asta Ginasih Amelia, Ditha Andina, Cantika Andriyani Rahmah Fahriati Anggel Imelda Ranboki Anis Dwi Kristiyowati Anjeli Rahmawati Ansori, Andika Al Assyifa Rachma Citra Aurli Fitria Ayu Werawati Azizah Nurma Qurotul ‘Aini Azzahra, Fathia Beny Maulana Satria Bheta Sari Dewi Cahyani, Lufitha Evelyne Chasanah, Eneng Uswatun Dara, Nabila Dea Ayu Anggraeni, Dea Ayu Anggraeni Denisa, Dila Dewi Astuti, Mardyana Dhea Mutiara Diah Permata Sari DIAH PERMATA SARI, DIAH PERMATA Dimas Agung Waskito Wijanarko Dinah Suwaybatul Aslamiyah Dinda Yuliantika Elena Prida Elza Tiani Lestari Evani, Azmi Zauli Fadiya Qotrunnada Fajrin, Aulia Farah Aulia Qatrunnada A Farhan Aziz, Muhammad Febriyanti, Nabila Fenita Purnama Sari Indah Frederico, Frederico Fu'adah, Intan Tsamrotul Gandes Winarni Getrudis Anita Seran Hapsari, Maretha Vien Helina Hermat Hermat Hersa, Mutiara Hidayatri, Nurul Humaira Fadhilah Ihsani, Salfia Ika Andini Ika Elvina Rahmawati Indiarti Ayu Silvia Ismiati, Hastin Kristiyowati, Anis Dwi Laelatun Nupus Larasati Larasati Larasati, Fannisa Dini Lestari, Bilqisti Rahmadani Lilik Febriyani Linawati Linawati Lisna Sari Luciana Luciana Mokodompit, Nurhaliza Martasya Muhamad Kholilu Navis Muhammad Ikhsanul Kahfi Muzaqil, Firmansyah Nabila N Nadia Shinta Purnomo Nanang Yunarto Nazila Khoerunnisa Novita Sary Nur Hasanah Nurhakiki, Nurhakiki Nurida Nurihardiyanti Nurihardiyanti, Nurihardiyanti Nurohmah, Alivia Octaviela, Tyara Oktaviani, Livia Ovia Airin, Ivo Pomalingo, Dwina Ramadhani Putri Nur Auliya Rahman Putri Sartika Rahma Shalsadilla Rahmalia, Rahmalia RIRIS ANDRIATI Rismiyanti, Aina Sahara, Khalipatun Sahira Madliya, Juliettania Salsabila, Fannysa Saputra, Teungku Raviola Saputri, Laras Tri Saputri, Safira Nurul Islam Sayyidah Sayyidah Sayyidah, Sayyidah Selvi Ramadani Silfiana, Ayu Sirait, Sertiwan Siti Chodijah Siti Fauziah Ahmad Suny Koswara Rahajeng SUSANTI Susanti Susanti Syuhriah Syuhriah Tiara Fitri Anggraeni Utami, Anissa UZ, LM Zulfahrin Vien Hapsari, Maretha Vina Fauziah Yollanda, Ade Yuhareza Aulia Eka Putri, Yuhareza Aulia Eka Putri Yulianingrum, Mutiara Yunita Yunita Zulfahrin, LM