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All Journal Jurnal Kimia Mulawarman The Indonesian Biomedical Journal Majalah Kesehatan FKUB Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Ilmiah Manuntung Jurnal Abdimas Mandiri Jurnal Kebidanan Mutiara Mahakam Buletin LOUPE (Laporan Umum Penelitian) Jurnal Kesehatan Pasak Bumi Kalimantan Jurnal Kedokteran Mulawarman International Journal of Multidisciplinary: Applied Business and Education Research Jurnal Medika: Karya Ilmiah Kesehatan Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Indonesian Journal of Pharmacology and Therapy Proceeding Mulawarman International Conference on Tropical Public Health
Nataniel Tandirogang
Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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KARAKTERISTIK BALITA PENDERITA PNEUMONIA BERDASARKAN FAKTOR RISIKO DI RSUD ABDUL WAHAB SJAHRANIE SAMARINDA TAHUN 2018 Fatimah, Nurul; Sukartini; Tandirogang, Nataniel
Jurnal Kebidanan Mutiara Mahakam Vol 8 No 1 (2020)
Publisher : Sekolah Tinggi Ilmu Kesehatan Mutiara Mahakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36998/jkmm.v8i1.73

Abstract

Pneumonia is an acute respiratory infection that affects the lung parenchyma, which is still the leading cause of children under-five mortality throughout the world. Age 1-24 months, low birth weight, and undernourished are the risk factors for pneumonia. The purpose of this study was to determine the description of the characteristics of children under-five patients with pneumonia in Abdul Wahab Sjahranie Hospital Samarinda, based on the risk factors. This research is a descriptive observational study. The samples of this study were all the pneumonia children under-five patients who were hospitalized at Abdul Wahab Sjahranie Hospital in January-December 2018, according to the characteristics of the sample set by the researchers, which were taken by purposive sampling technique. The data used were secondary data obtained from patient medical records, taken in June 2019 at the Medical Record Installation, Abdul Wahab Sjahranie Hospital. The number of samples obtained was 42 pneumonia patients. More children suffering from pneumonia were found in age 1-24 months (78.6%), normal birth weight (61.9%), and undernourished (57.1%).
UJI FITOKIMIA DAN ANTIOKSIDAN EKSTRAK ETANOL PROPOLIS LEBAH KELULUT (TETRAGONULA IRIDIPENNIS) DARI SAMARINDA KALIMANTAN TIMUR Khairunnisa, Binti; Rosamah, Enih; Kuspradini, Harlinda; Kusuma, Irawan Wijaya; Sukemi, Sukemi; Tandirogang, Nataniel; Arung, Enos Tangke
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

The study aims to identify the secondary metabolite compounds contained in the ethanol extract Propolis Tetragonula Iridipennis and determine the antioxidant activity. Propolis is extracted from the beehive of Kelulut (Tetragonula Iridipennis) with a method of maceration of ethanol 96% produce a yield of 66.73%. Propolis extract contains alkaloid compounds, flavonoids, triterpenoids, tannins and carbohydrates. Propolis extract tested its antioxidant activity using the DPPH method (1.1-diphenyl-2-picrylhydrazyl) with a wavelength of 514 nm. Results showed a percentage of propolis extract free radicals 59% in concentrations of 100 ppm with IC50 33.74 ppm so that propolis extract is potentially as an antioxidant.  
PERBEDAAN NILAI RASIO NEUTROFIL-LIMFOSIT PRE DAN POST OPERASI CORONARY ARTERY BYPASS GRAFTING ON-PUMP TERHADAP KEJADIAN ACUTE KIDNEY INJURY DAN NON-ACUTE KIDNEY INJURY Septa Ariany; Ivan Joalsen Mangara Tua; Danial Danial; Nataniel Tandirogang
Jurnal Kedokteran Mulawarman Vol 8, No 3 (2021): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/j.ked.mulawarman.v8i3.6749

Abstract

Acute Kidney Injury (AKI) adalah sindrom kompleks yang ditandai dengan penurunan fungsi ginjal. Pada penelitian ini, rasio neutrofil-limfosit (RNL) yang tinggi dikaitkan dengan perkembangan AKI setelah Coronary Artery Bypass Grafting On-Pump (CABG on-pump). Penggunaan RNL sebagai parameter yang tersedia dengan mudah untuk mendeteksi pasien yang berisiko terkena AKI. Tujuan penelitian untuk mengetahui perbedaan nilai RNL pasca operasi CABG on-pump terhadap kejadian AKI dan Non-AKI. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Semua data klinis preoperative dan postoperative diambil sebagai data sekunder dari rekam medik pasien yang menjalani CABG di Rumah Sakit Umum Daerah Abdul Wahab Sjahranie (RSUD AWS) Samarinda periode Januari 2017-Desember 2020. Penelitian menggunakan uji statistik dengan Mann-Whitney dan Uji Regresi. Hasil penelitian ini ditemukan 41,1% dari 56 sampel mengalami AKI. Hasil didapatkan bahwa terdapat perbedaan nilai RNL pasca operasi pada sampel AKI dan Non-AKI dengan nilai p=0,008. Peningkatan RNL ≥ 10 kali risiko sebesar 6,352 kali lipat.
HUBUNGAN JARAK FKTP KE FKRTL DAN KETERSEDIAAN LABORATORIUM SATU ATAP TERHADAP RUJUKAN NON SPESIALISTIK DI FKTP KOTA SAMARINDA TAHUN 2020 Enjelina Febri Adi Melinia; Rahmat Bakhtiar; Nataniel Tandirogang
Jurnal Kedokteran Mulawarman Vol 8, No 3 (2021): Jurnal Kedokteran Mulawarman
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/j.ked.mulawarman.v8i3.6874

Abstract

Jaminan Kesehatan Nasional dibentuk oleh pemerintah agar seluruh masyarakat Indonesia dapat menerima pelayanan kesehatan. Pelayanan kesehatan dilakukan secara berjenjang dengan pelayanan pertama pada fasilitas kesehatan tingkat pertama (FKTP) sesuai dengan kompetensi dokter dan dapat dilakukan rujukan ke jenjang berikutnya jika sesuai dengan indikasi dilakukan rujuk. Penelitian ini bertujuan untuk mengetahui hubungan jarak FKTP ke fasilitas kesehatan rujukan tingkat lanjut (FKRTL) dan ketersediaan laboratorium satu atap terhadap rujukan non spesialistik di FKTP Kota Samarinda tahun 2020. Penelitian ini merupakan penelitian analitik observasional. Populasi penelitian ini adalah FKTP Kota Samarinda yang bekerjasama dengan Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan) dengan besar sampel 106 FKTP yang ditentukan menggunakan teknik purposive sampling. Data diperoleh dari data BPJS Kesehatan Kota Samarinda dan dianalisis menggunakan uji Chi-Square. Hasil penelitian menunjukkan tidak terdapat hubungan jarak FKTP ke FKRTL terhadap rujukan non spesialistik (p=0,451), tetapi terdapat hubungan ketersediaan laboratorium satu atap terhadap rujukan non spesialistik (p=0,012) di FKTP Kota Samarinda tahun 2020.
Evaluations of Antibacterial Properties of Zingiber purpureum Essential Oil Against 13 Different Gram-positive and Gram-negative Bacteria Nataniel Tandirogang; Silvia Anitasari; Enos Tangke Arung; Swandari Paramita; Yung Kang Shen
The Indonesian Biomedical Journal Vol 14, No 3 (2022)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v14i3.1967

Abstract

BACKGROUND: Indonesia's tropical forest is home to around 80% of the world's medicinal plants. One of these is Zingiber purpureum, which have traditionally been used to treat joint discomfort, the common cold, and jaundice. The rhizomes of this plant have been suggested to possess antibacterial action in the treatment of infections. In this study, Z. purpureum was screened for antibacterial activity against 13 bacteria (Gram-positive and Gram-negative).METHODS: Z. purpureum rhizomes were obtained and the distillated extracts were made to generate essential oil. The minimum inhibitory concentration (MIC) and Kirby Bauer disk diffusion methods were used to determine the antibacterial activity.RESULTS: All bacteria activity were inhibited by the essential oil of Z. purpureum at concentrations ranging from 2.5 vol% to 10 vol%. However, several bacterias (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) were inhibited at the lowest concentration (0.63 vol %), with the inhibition zones ranging from 6.7 mm to 8.0 mm. Meanwhile, the widest inhibition zone (13.3 mm) was reported on E. cloacae at 10 vol% concentration.CONCLUSION: A 10 vol% Z. purpureum rhizome extract inhibits Gram-positive and Gram-negative bacteria, particularly those that are resistant to a variety of antibiotics.KEYWORDS: Zingiber purpureum, antibacterial agents, susceptibility test, infection
Neutralizing Antibody Response by Inactivated SARS-CoV-2 Vaccine on Healthcare Workers Nataniel Tandirogang; Evi Fitriany; Nursaci Mardania; Miftahul Jannah; Bilqis Faiqotun Nabilah Dilan; Sapta Rahayuning Ratri; Arfian Deny Prakoso; Meiliati Aminyoto; Yuliana Kartika Ningrum; Ika Fikriah; Yadi Yadi
Molecular and Cellular Biomedical Sciences Vol 7, No 1 (2023)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v7i1.303

Abstract

Background: Currently, the key to combat coronavirus disease 2019 (COVID-19) as a global pandemic is relying mainly on vaccination, and several factors might affect the level of protection. This study aimed to determine the quantitative increase of neutralizing antibody titer against COVID-19 and the influence of gender, body mass index (BMI), routine consumption of vitamin C, D, and E towards the neutralizing antibodies after vaccination.Materials and methods: One hundred nine health workers from various health facilities were recruited. Sinovac inactivated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccine was used in this study. Antibody titer measurements were carried out quantitatively using electrochemiluminescence immunoassay (ECLIA) on day 14 after the first and second doses administration of the vaccine.Results: The average of antibody titers after the first and second doses were 109.1 and 191.6 U/mL, respectively. Antibody titer significantly increased (p=0.000) as much as 82.5 U/mL from the first to the second dose. There was a significant difference in the increase in antibody titer between respondents who consumed vitamin E regularly and those who did not (p=0.036). Routine consumption of vitamin C and D, gender, and BMI did not affect the increase in neutralizing antibody titer with p-values of 0.983, 0.337, 0.186, and 0.424, respectively.Conclusion: Routine consumption of vitamin E is associated with post-SARS-CoV-2 vaccination neutralizing antibody response. Gender, BMI, and the routine consumption of vitamin C and D have no association with the immune response.Keywords: COVID-19, neutralizing antibody, inactivated SARS-CoV-2 vaccine
HUBUNGAN FAKTOR SOSIODEMOGRAFI, KLINIS, DAN PENGAWAS MINUM OBAT TERHADAP KEBERHASILAN PENGOBATAN TUBERKULOSIS PARU DI PUSKESMAS RAPAK MAHANG TENGGARONG Fadilla, Shella; Moerad, Emil Bachtiar; Tandirogang, Nataniel
Jurnal Medika : Karya Ilmiah Kesehatan Vol 8 No 2 (2023): Jurnal Medika Karya Ilmiah Kesehatan
Publisher : ITKES Wiyata Husada Samarinda

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Abstract

Tuberculosis (TB) is a contagious and infectious disease caused by Mycobacterium tuberculosis which mainly affects the lungs. Due to its high morbidity and mortality rate, it is necessary to control and manage it with tuberculosis treatment program. The indicator for evaluating this program focusses on the treatment success rate. One way to reach tuberculosis treatment success rate is analyzing factors concerning the result treatment. This study aims to investigate the correlation among socio-demographic factors (i.e. age, sex, distance of residence, and education), clinical factors (i.e. diagnosis type and Diabetes Melitus (DM) status), and drug consumption supervisor towards treatment success for pulmonary tuberculosis. The design of this study was anaytical observational with cross-sectional approach. Applying total sampling technique, the data were collected from Tuberculosis Information System, TB form, and medical records at TBDOTS (Directly Observed Treatment Short-course) Unit of Rapak Mahang Public Health Centre in Tenggarong from 2020 to 2022. There were 94 samples fulfilling inclusion and exclusion criteria. The data were analyzed using Fisher’s Exact test. The results of statistical analysis including age, sex, distance of residence, education, diagnosis type, DM status, and drug consumption supervisor were shown by p value of 0,454; 0,548; 1,000; 1,000; 0,573; 0,410; and 1,000 consecutively. Therefore, it can be concluded that each of these following factors: age, sex, distance of residence, education, diagnosis type, DM status, and drug supervisor is not significantly correlated with the treatment success for pulmonary TB.
Validity and Reliability Test of the Procrastination Assessment Scale-Student Questionnaire Part 2 Indonesian Version Uji Validitas dan Realibilitas Kuesioner Procrastination Assessment Scale-Student Bagian 2 Versi Bahasa Indonesia Azkiah, Wa Ode Nurul; Abdullah, Yenny; Tandirogang, Nataniel
Jurnal Medika : Karya Ilmiah Kesehatan Vol 9 No 1 (2024): Jurnal Medika Karya Ilmiah Kesehatan
Publisher : ITKES Wiyata Husada Samarinda

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Abstract

Abstract Academic procrastination is the behavior of procrastinating or procrastinatingComplete academic assignments based on your own wishes. QuestionnaireProcrastination Assessment Scale-Student (PASS) is a questionnaire to find outstudent academic procrastination. This questionnaire consists of 2 parts, part 1 discussesprevalence of academic procrastination and part 2 discusses the reasons for procrastination. StudyThis aims to obtain the Indonesian version of the PASS questionnaire part 2valid and reliable. The type of research is cross sectional research. The questionnaire consists of26 question items distributed via Google form to 30 active students of the Study ProgramMulawarman University Medicine in January-February 2022. Carried outadaptation and translation of PASS part 2 into Indonesian, followed by validity testingcontent and construct validity tests using the Pearson correlation test and reliability testusing Cronbach's alpha value. The validity test results show that there are 2 items that are notvalid (r < 0.361) and the results of the reliability test show that the questionnaire is reliable with Cronbachalpha coefficient of 0.894 (α > 0.7). The research conclusion is that there are 2 items droppedin this questionnaire and the Indonesian version of PASS part 2 are valid and reliable for measuringreasons for academic procrastination of University Medical Study Program studentsMulawarman. Therefore, the Indonesian version of PASS part 2 can be usedto measure the reasons for students' academic procrastination.
PERBANDINGAN KADAR VITAMIN D PADA SERUM PASIEN COVID-19 DENGAN ANGGOTA KELUARGA SERUMAH YANG SEHAT Tandirogang, Nataniel; Nuryanto, Muhammad Khairul; Ningrum, Yuliana Kartika; Saputra, Rudi; Aminyoto, Meiliati
Majalah Kesehatan Vol. 10 No. 3 (2023): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2023.010.03.4

Abstract

Imunitas merupakan faktor penting dalam mencegah infeksi COVID-19. Vitamin D memiliki peran penting dalam mengatur dan menjaga sistem imun tubuh terutama terhadap infeksi virus. Penelitian ini bertujuan untuk mengetahui perbedaan kadar serum vitamin D antara pasien COVID-19 dengan anggota keluarga serumah yang sehat. Penelitian ini merupakan penelitian cross-sectional dengan subjek penelitian berjumlah 72 responden dari 25 rumah tangga dengan salah satu anggota keluarganya menderita COVID-19. Penentuan status COVID-19 responden menggunakan pemeriksaan real-time PCR (RT-PCR). Pasien COVID-19 ini dirawat di RSUD Abdoel Wahab Sjahranie atau menjalani isolasi mandiri di rumah masing-masing. Kadar vitamin D ditentukan dengan mengukur total kadar vitamin D 25-OH menggunakan metode  electrochemiluminescence immunoassay (ECLIA) di laboratorium terstandarisasi. Data dianalisis menggunakan independent T-Test dengan signifikansi p<0,05. Rerata kadar serum vitamin D total responden adalah 20,25 ng/mL. Sebanyak 91,7% responden mengalami kekurangan vitamin D dengan rincian pasien COVID-19 memiliki rata-rata kadar serum vitamin D pasien COVID-19 sebesar 21,3 ng/mL (insufisiensi), sedangkan orang sehat adalah 19,2 ng/mL (defisiensi).. Tidak ada perbedaan yang signifikan kadar serum vitamin D antara pasien COVID-19 dengan anggota keluarga serumah yang sehat (p=0,231). Kesimpulan penelitian ini adalah tidak ada perbedaan yang signifikan pada kadar serum vitamin D pasien COVID-19 dengan anggota keluarga serumah yang sehat, namun prevalensi kekurangan vitamin D sangat tinggi.
Potensi Ekstrak Etanol Rimpang Jeringau (Acorus calamus L.) Sebagai Spasmolitik Marihot Pasaribu; Nataniel Tandirogang; Sjarif Ismail; Swandari Paramita; Agustina Rahayu Magdaleni; Hary Nugroho
Jurnal Sains dan Kesehatan Vol. 1 No. 7 (2017): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i7.53

Abstract

Pain due to smooth muscle stiffness can occur in various circumstances of patients, ranging from normal circumstances such as menstrual pain, to a pathological condition of gastrointestinal infections. To overcome the pain it can be given medication to reduce muscle stiffness as spasmolytics, but there are side effects of the drug. Thus, the need for developing new spasmolytics drugs based on medicinal herbs with fewer side effects. This study was conducted to examine the potential of rhizome extract of jeringau (Acorus calamus L.) that is traditionally used by Dayak tribe to heal upset stomach. Spasmolytic activity of plant extracts tested with isolates organ methods of guinea pig ileum induced by histamine. Result of the study showed 0.3 mg/ml A. calamus rhizomes extract could decrease ileum contraction better than papaverine 0.03 mg/ml (p=0.00). The conclusion of this study is rhizome extract of jeringau (A. calamus) has the potential to be used as spasmolytics in treatment of health problems caused by smooth muscle contraction
Co-Authors Abdullah, Yenny Adi Susanto Alhawaris, Alhawaris Anggraini, Fitria Dewi Puspita Arfian Deny Prakoso Azkiah, Wa Ode Nurul Bakhtiar, Rahmat Bilqis Faiqotun Nabilah Dilan Binti Khairunnisa Budi Santoso Nong Ulir Danial Danial Daniel Daniel Edy Wibowo Kurniawan Enih Rosamah Enjelina Febri Adi Melinia Enos Tangke Arung, Enos Tangke Evi Fitriany Fadilla, Shella Fikriah, Ika Harlinda Kuspradini Hary Nugroho Irawan Wijaya Kusuma, Irawan Wijaya Ivan Joalsen Mangara Tua Khairunnisa, Binti Khemasili Kosala Krispinus Duma Magdaleni Agustina Rahayu Marihot Pasaribu Meiliati Aminyoto Miftahul Jannah Moerad, Emil Bachtiar Ningrum, Yuliana Kartika Nur Khoma Fatmawati Nurkhalisa, Nina Nursaci Mardania Nurul Fatimah Nurul Khumaida Nuryanto, Muhammad Khairul Pramulia Yudia, Riries Choiru Rahmat Bakhtiar Rasendriya , Fauzan Firjatullah Rasendriya, Fauzan Firjatullah Rosamah, Enih Rudito Sapta Rahayuning Ratri Saputra, Rudi Septa Ariany Silvia Anitasari Sjarif Ismail Sormin, Hendro Jatmiko Sukemi Sukemi Suwadi Swandari Paramita Yadi Yadi Yadi Yadi Yasir Yadi, Yadi Yuliana Kartika Ningrum Yulianti, Martina Yundari, Yundari Yung Kang Shen Yuniati Yuniati