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All Journal Jurnal Keperawatan dan Kesehatan Masyarakat CENDEKIA UTAMA Pharmacon Sains Natural: Journal of Biology and Chemistry Cendekia Journal of Pharmacy Jurnal Pengabdian Kesehatan Natural Sciences Engineering and Technology Journal Community Medicine and Education Journal APMa Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Bestari (JPMB) Jurnal Farmasi Sains dan Praktis Jurnal Pengabdian Bersama Masyarakat Indonesia Jurnal Pengabdian Bidang Kesehatan Jurnal Medicare Compromise Journal : Community Proffesional Borneo Journal of Pharmacy JPKM Cahaya Negeriku
Dian Arsanti Palupi
Institut Teknologi Kesehatan Cendekia Utama Kudus
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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PENGARUH PEMBERIAN KOMBINASI EKSTRAK DAUN PEPAYA(Carica papaya L.) DAN AKTIVITAS FISIK TERHADAP KADAR GLUKOSA DARAH MENCIT DIABETES MELITUS TIPE II Dian Arsanti Palupi; Irsha Intan Armita; Lilis Sugiarti
Cendekia Journal of Pharmacy Vol 7, No 1 (2023): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v7i1.226

Abstract

Diabetes Melitus tipe II terjadi akibat adanya kerusakan atau gangguan sekresi insulin. Ekstrak daun pepaya (Carica papaya L.) memiliki kandungan senyawa kimia flavonoid, tanin dan saponin. Aktivitas fisik secara teratur dapat memperbaiki kadar glukosa darah pada penderita diabetes mellitus. Penelitian ini bertujuan untuk menurunkan glukosa darah pada mencit diabetes melitus tipe II dengan desain pre and post test control group dsign, menggunakan 30 ekor mencit jantan Swiss Webster dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif CMC Na (K1), kelompok kontrol positif Glibenklamid (K2), kelompok ekstrak daun pepaya (K3), kelompok aktifitas fisik (K4) dan kelompok kombinasi ekstrak daun pepaya dan aktivitas fisik (K5). Diinduksi aloksan kemudian dipuasakan 12 jam diukur kadar glukosa (pre test) 126 mg/dL. Pemberian ekstrak diberikan p.o 1 kali sehari selama 12 hari dan aktivitas fisik dilakukan 3 hari sekali, pada hari ke 12 dilakukan pemeriksaan kadar glukosa darah (Post test). Hasil penelitian menunjukan bahwa kombinasi ekstrak daun pepaya dan aktivitas fisik berenang tidak berbeda signifikan dengan kontrol positif nilai p.0.093. Kesimpulan, ekstrak daun pepaya mengandung flavonoid, tanin dan saponin dikombinasi dengan aktivitas fisik berenang mampu menurunkan kadar glukoksa darah sebear 45,81%.
POTENSI EKSTRAK ETANOL KONSORSIUM HERBAL (DAUN SALAM, DAUN KEMANGI, DAUN KERSEN, dan DAUN CIPLUKAN) TERHADAP PERTUMBUHAN BAKTERI Propionibacterium acnes Lilis Sugiarti; Mila Ayu Setianingsih; Dian Arsanti Palupi
Cendekia Journal of Pharmacy Vol 7, No 2 (2023): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v7i2.246

Abstract

Jerawat merupakan suatu keadaan ketika pori-pori kulit tersumbat sehingga menimbulkan bintik merah dan abses (kantong nanah) yang meradang dan terinfeksi oleh bakteri. Tanaman obat yang berpotensi sebagai antibakteri sangat banyak ditemukan di Indonesia antaranya yaitu daun salam, daun kemangi, daun kersen, dan daun ciplukan. Kandungan bahan aktif dari tanaman tersebut yaitu flavonoid, saponin, tanin, minyak atsiri. Penelitian ini bertujuan untuk mengetahui potensi antibakteri pada konsorsium herbal terhadap bakteri Propionibacterium acnes. Proses ekstraksi dalam penelitian ini yaitu dengan menggunakan metode maserasi. Serbuk simplisia konsorsium herbal diekstraksi dengan pelarut etanol 70%. Ekstrak dibuat seri konsentrasi 10%, 25%, 40%, 55%, dan 70% dengan kontrol negatif (DMSO 1%) dan kontrol positif (kapsul klindamisin 2%) terhadap bakteri uji Propionibacterium acnes dengan metode difusi cakram. Hasil yang didapatkan dianalisis menggunakan uji One Way Anova, Korelasi, dan Regresi linear. Hasil dari analisis diameter zona hambat terhadap Propionibacterium acnes diperoleh nilai signifikan 0,000 (p0,05). Konsentrasi hambat terbesar terdapat pada konsentrasi 70% dalam kategori kuat. Hasil uji korelasi menunjukkan adanya hubungan yang sangat kuat dan searah antara besarnya konsentrasi dengan diameter zona hambat. Hasil uji regresi linier diperoleh persamaan  Y = 0,1349 x +3,6093 yang berarti setiap kenaikan konsentrasi ekstrak 1% mampu menaikan diameter zona hambat sebesar 0,1349 mm dengan diameter awal 3,6093 mm. Ekstrak etanol konsorsium herbal memiliki potensi sebagai antibakteri terhadap bakteri Propionibacterium acnes
Antiasthma Activities of Moringa oleifera Lam. Leaves Extract on the Eosinophil Count and Mast Cells in BALB/c Mice Dian Arsanti Palupi; Tri Wahyuni Prasetyowati; Dwi Murtiningsih; Dede Mahdiyah
Borneo Journal of Pharmacy Vol. 4 No. 3 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i3.1916

Abstract

Asthma is a chronic inflammation of the respiratory tract. This study aimed to prove Moringa oleifera Lam. leaves extract's effect on reducing the eosinophil count and mast cells in asthmatic mice. Twenty BALB/c mice that met the inclusion criteria were divided into four groups of standard control (K1), negative control (K2), dexamethasone (K3), and M. oleifera leaves extract (K4). On days 0 and 7, intraperitoneal ovalbumin (OVA) was sensitized. On days 14, 16, and 18, mice were re-sensitized by inhalation using 1% OVA in sterile 0.9% NaCl. On days 18 to 25, K1 and K2 groups were given Na-CMC, the K3 group was given dexamethasone 1.3 µg/day, and the K4 group was given M. oleifera leaves extract 3.9 mg/day. On the 25th day, the mice were terminated to analyze the eosinophil count and stable bronchiolar mast cells. In conclusion, M. oleifera leaves extract was proven to decrease the eosinophil count with a p-value <0.05 and could stabilize bronchiolar mast cells with a p-value <0.05.
Pelatihan Pengolahan Wortel Menjadi Stick Sehat Pengontrol Kadar Glukosa Darah Bagi Ibu PKK di Desa Temulus Mejobo Kudus Rifda Naufa Lina; Annis Rahmawaty; Heni Setyoningsih; Hasty Martha Wijaya; Yulia Pratiwi; Dian Arsanti Palupi; Lilis Sugiarti; Chabbah Tri Septian; Wara Madia
Jurnal Pengabdian Bidang Kesehatan Vol. 2 No. 1 (2024): Jurnal Pengabdian Bidang Kesehatan
Publisher : PPNI UNIMMAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jpbidkes.v2i1.50

Abstract

Carrots are a type of tuber vegetable that is rich in antioxidant compounds, including vitamin C and beta carotene. One of the functions of antioxidants is to protect pancreatic beta cells from free radical attacks and is also a vasodilator in preventing cardiovascular disorders Damage to pancreatic beta cells can result in high blood glucose levels. Carrots have a taste are not pleasant to consume, so they are made in stick form, which is a snack that is easy to consume every day with a delicious taste and is effective in controlling blood glucose levels. The aim of this activity is to increase the knowledge, skills of PKK’s mother in Temulus about the benefits of carrots and how to process them into healthy sticks so they are delicious to consume. The methods used are descriptive, explanation, discussion and practice. The result of this activity was an increase in knowledge from the good category of 10% (3 people) to 46.67% (14 people) with a total of 30 participants. The conclusion of this activity is the increasing knowledge of PKK mothers in Temulus about the benefits of carrots as controlling blood glucose levels and increasing the skills of PKK mothers in Temulas in processing carrots into healthy sticks to control blood glucose levels.
Analgesic Activity Combination of Dry Extract of Meniran Leaves (Phyllanthus niruri L.) and Moringa Leaves (Moringa oleifera L.) Using the Chemical Induction Method: Invivo Study Dian Arsanti Palupi; Sugiarti, Lilis; Eni Yulianti
Natural Sciences Engineering and Technology Journal Vol. 4 No. 1 (2024): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v4i1.53

Abstract

Analgesics are drugs that selectively reduce pain in the central nervous system or peripheral pain mechanisms without significantly changing consciousness. This study aims to determine the analgesic activity of a combination of dry extracts of meniran leaves (Phyllanthus niruri l.) and moringa leaves (Moringa oleifera l.) against Swiss Webster rats with chemical induction methods. This research proves the presence of secondary metabolite content in the dry extract of meniran leaves and moringa leaves which have analgesic activity. The research used 30 male Swiss Webster rats divided into 5 groups. Group 1 is the negative control (CMC-Na 0.5%), group 2 is the positive control (diclofenac Na), group 3 (Dry extract of meniran leaves), group 4 (Dry extract of moringa leaves) and Group 5 (Combination of dry extracts). meniran and moringa leaves). Each was given 1 mL of 1% acetic acid induction chemical stimulation, then the writhing response was observed and recorded at 5-minute intervals for 30 minutes. The results showed that the K3 group combined dry extract of meniran leaves (Phyllanthus niruri L.) and moringa leaves (Moringa oleifera L) is not statistically significantly different from the positive control diclofenac sodium, p-value = 0.183. In conclusion, dry extract of meniran leaves (Phyllanthus niruri L.) and Moringa leaves (Moringa oleifera L.) has been proven to contain secondary metabolites of flavonoids, alkaloids, tannins, and saponins which have analgesic activity.
PENCEGAHAN ANEMIA PADA REMAJA DAN PENATALAKSANAAN SECARA NON FARMAKOLOGI DI SMK N 1 REMBANG Alvi Ratna Yuliana; Dian Arsanti Palupi; Dessy Erliani Mugita Sari; Endra Pujiastuti; Dwi Susiloningrum; Ricka Islamiyati
Jurnal Pengabdian Bersama Masyarakat Indonesia Vol. 2 No. 4 (2024): Oktober : Jurnal Pengabdian Bersama Masyarakat Indonesia
Publisher : CV. Aksara Global Akademia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59031/jpbmi.v1i1.70

Abstract

Adolescent girls are a vulnerable group to experience anemia, if there are no prevention efforts, awareness among adolescents about the problem of anemia will affect problems in growth and development, both physically and academically. The main cause of anemia is insufficient intake of iron which cannot be obtained without only by taking blood-boosting drugs but this can be done by consuming a variety of foods that fulfill the nutrients containing iron, vitamins to prevent anemia, where teenagers nowadays pay less attention to healthy food intake. The purpose of this community service is to increase the level of student knowledge/ students through education about anemia, knowing the risk factors for anemia in adolescents, knowing the physical characteristics or symptoms and the consequences that arise from anemia and providing education about the treatment of anemia in addition to using pharmacological drugs, one of which is by consuming foods that contain Contains vitamins and iron to increase Hemoglobin levels in the blood. The activity method consists of three, namely planning, implementation and evaluation. This counseling was carried out offline at SMKN 1 Rembang with 40 students. Based on the results of the pre-test and post-test, it can be concluded that there was an increase in students' knowledge about anemia prevention and non-pharmacological management. increasing knowledge of young women before and after education
Cegah Stunting dengan Puding Daun Kelor pada Ibu Hamil di Desa Loram Wetan Kudus Dian Arsanti Palupi; Yulia Pratiwi; Dwi Susiloningrum; Lilis Sugiarti; Annis Rahmawaty; Icha Vidyani Setyana Wati; Ana Dwi Rizkina; Astin Dwi Wardini
Compromise Journal Community Proffesional Service Journal Vol. 3 No. 2 (2025): Compromise Journal : Community Proffesional Service Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/compromisejournal.v3i2.724

Abstract

Stunting was growth failure in children caused by chronic malnutrition or infectious disease, resulting in impaired physical and cognitive growth. This community service suggests using Moringa oleifera leaves to prevent stunting by making pudding. Moringa leaves are famous for their high nutritional value, containing vitamins A, C, and E and minerals such as calcium, iron, and protein. This community service program aims to increase the skills and knowledge of the community, especially pregnant women, in making Moringa leaf pudding and the importance of improving nutrition in pregnant women. The method used was descriptive, lecture, discussion and direct practice in making Moringa leaf pudding with village midwives, pregnant women at the posyandu in Loram Wetan Kudus village. The results of this community service activity can be seen from the increase in participants' knowledge and ability to make Moringa leaf pudding correctly according to the instructions that have been given previously. This community service activity concludes that participants can make Moringa leaf pudding independently and increase pregnant women's knowledge about the benefits of Moringa leaves, which are rich in nutrients and can be used to improve nutritional status to reduce the incidence of stunting.
PERAN TINGKAT PENDIDIKAN TERHADAP PENGETAHUAN PENYIMPANAN DAN PEMBUANGAN OBAT DI RUMAH PADA PASIEN RAWAT JALAN RSI SUNAN KUDUS Pratiwi, Yulia; Khoiriyah; Annis Rahmawaty; Dian Arsanti Palupi; Rifda Naufa Lina; Jarot Yogi Hernawan
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.240

Abstract

Improper storage and disposal of medications at home can reduce drug quality, pose risks of poisoning, and contribute to environmental pollution. However, public knowledge remains low, as only 16.1% of respondents demonstrated good understanding of proper storage, and 52.6% lacked awareness of safe disposal methods. Education is considered a key factor in improving health literacy related to medication management. This study aimed to examine the relationship between educational level and knowledge of medication storage and disposal among outpatients at RSI Sunan Kudus. The research employed a descriptive quantitative approach, involving 392 respondents selected through purposive sampling. Data were analyzed using univariate analysis and Spearman Rank correlation. The majority of respondents were female (71.4%), aged 26–45 years (47.2%), had a senior high school/vocational education (53.8%), and were employed in the private sector (56.9%). Most respondents had moderate knowledge regarding storage (55.4%) and disposal (44.6%) of medications. A significant relationship was found between education level and knowledge of both storage (r = 0.532; p < 0.001) and disposal (r = 0.610; p < 0.001). More intensive education by pharmaceutical staff is recommended.
Sosialisasi Dan Bakti Sosial Pembagian Masker Dan Hand Sanitizer Kepada Masyarakat Sebagai Upaya Mengurangi Angka Penyebaran Covid-19 Dwi susiloningrum; Susan Primadevi; Dian Arsanti Palupi; Lilis Sugiart; Endra Pujiastuti
Jurnal Pengabdian kepada Masyarakat Cahaya Negeriku Vol. 2 No. 1 (2022): Jurnal Pengabdian kepada Masyarakat Cahaya Negeriku
Publisher : LPPM AN Nuur

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background Since 2020, Indonesia has experienced the Covid-19 pandemic, and large-scale social restrictions (PSBB) have begun to be implemented. The number of Covid-19 sufferers in Indonesia has increased from 2020- 2021. One of the efforts to overcome this increase is by providing social services for distributing masks and hand sanitizers to the public. Purpose: Efforts to reduce the number of Covid-19 in society. Method: Distribution of masks and hand sanitizers in the tourist area of the Menara Kudus as well as an explanation of how to use them orally. ResultsThe 100 people who were targeted were already wearing masks and hand sanitizers. Conclusion: People in the tourist area of Menara Kudus, people already wear masks and hand sanitizers when they leave the house  
Co-Authors Achmad Junaedi Alvi Ratna Yuliana Ana Dwi Rizkina Annis Rahmawaty Annis Rahmawaty Annis Rahmawaty Astin Dwi Wardini Chabbah Tri Septian Clara Destiana Caesary Dede Mahdiyah Dessi Erliani Mugita Sari Dessy Erliani Mugita Sari Dessy Erliani Mugita Sari Dwi Murtiningsih Dwi Susiloningrum Dwi Susiloningrum Eliana Freistanti Elma Martati Endra Pujiastuti Endra Pujiastuti Endra Pujiastuti Endra Pujiastuti Eni Yulianti Fajrunida Nur Hasanah Hasty Martha Wijaya Heni Setyoningsih Heni Setyoningsih Icha Vidyani Setyana Wati Indah Febriana Irsha Intan Armita Jarot Yogi Hernawan Khoirin Nida Khoiriyah Kristin Catur Sugiyanto Lidya Anita Safitri Lilis Sugiart Lilis Sugiarti Lilis Sugiarti Lilis Sugiarti Lilis Sugiarti Lilis Sugiarti Lilis Sugiarti Mila Ayu Setianingsih Miyati Miyati Nadhifah Luqyana Noor Laili Agustina Nufika Musyafaah Putri Ika Wardani Rakhmi Hidayati Ricka Islamiyati Ricka Islamiyati Rifda Naufa Lina Rifda Naufa Lina Rifda Naufa Lina Rifda Naula Lina Risna Endah Budiati Rohmatun Nafi&#039;ah Salwa Rahmawati Susan Primadevi Susan Primadevi Syauqi Afifatul Amiroh Tri Wahyuni Prasetyowati Vasti Eka Apriliani Wara Madia Yeni Krisma Dewi Yenny Adyastutik Yulia Pratiwi Yulia Pratiwi Yulia Pratiwi Yulia Pratiwi Yulia Pratiwi