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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sain Veteriner Jurnal Kesehatan Lingkungan indonesia e-Journal Pustaka Kesehatan Althea Medical Journal Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) The Indonesian Journal of Occupational Safety and Health UNEJ e-Proceeding Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner Hearty : Jurnal Kesehatan Masyarakat J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Journal of Health Sciences ARTERI : Jurnal Ilmu Kesehatan JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH MAHESA : Malahayati Health Student Journal Solo Journal of Anesthesi, Pain and Critical Care JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat Jember Medical Journal (JMJ) Indonesian Journal of Biomedicine and Clinical Sciences Journal of Agropharmacy Folia Medica Indonesiana
Wiwien Sugih Utami
Department Of Parasitology, Faculty Of Medicine, Universitas Of Jember, Jember 68121, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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The Relationship between Knowledge and Attitude of Slaughterhouse Workers in Relation with Cattles' Fascioliasis as an Effort to Prevent Halzoun Syndrome in Jember Hermansyah, Bagus; Salsabilla, Safira Putri Nur; Febrianti, Zahrah; Utami, Wiwien Sugih; Armiyanti, Yunita
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.102910

Abstract

Prevalensi fascioliasis pada sapi di Jember mencapai 56,6%, sehingga berpotensi menimbulkan kerugian ekonomi di Indonesia sekitar 6,9 miliar rupiah. Mengonsumsi hati sapi mentah atau setengah matang yang terkontaminasi cacing Fasciola spp. dewasa dapat menyebabkan sindrom halzoun, yaitu reaksi hipersensitivitas yang mengenai mukosa bukafaring dan saluran pernapasan atas. Pencegahan sindrom halzoun yang efektif memerlukan penerapan prinsip “ASUH” oleh pekerja rumah potong hewan, yang harus memiliki pengetahuan yang baik dan sikap proaktif terhadap tugasnya. Penelitian ini bertujuan untuk mengkaji hubungan antara pengetahuan dan sikap pekerja rumah potong hewan dengan prevalensi fascioliasis pada sapi sebagai upaya pencegahan sindrom halzoun di Jember. Desain penelitian yang digunakan adalah cross-sectional, dengan pengumpulan data dilakukan pada 35 pekerja di 9 rumah potong hewan di Jember pada bulan Agustus sampai dengan Desember 2024. Analisis menggunakan Uji Fisher's Exact. Hasil analisis menunjukkan nilai p untuk pengetahuan dan sikap terhadap fascioliasis pada sapi masing-masing adalah p=0,103 dan p=0,592. Kesimpulan dari penelitian ini adalah tidak terdapat hubungan yang signifikan antara pengetahuan dan sikap petugas rumah potong hewan dengan prevalensi fascioliasis pada sapi sebagai upaya pencegahan sindrom halzoun di Jember.
Comparison of anterior colporrhaphy and vaginal mesh therapy for pelvic organ prolapse: a systematic review and meta-analysis Mukhammad Arif Hadi Khoirudin; Nidia Nursafitri; Mauliya Sri Sukmawati Wahyudi; Muhammad Zainul Fikri; Dita Diana Parti; Wiwien Sugih Utami; Dian Eka Putri Harnandhari
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 3 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i3.19977

Abstract

Pelvic organ prolapse (POP) is a common pelvic disorder among women. Although it is not life-threatening, POP represents significant health concern because it can cause urinary incontinence, decrease sexual function, and impair quality of life. This systematically review was conducted to compare the effectiveness and safety of anterior colporrhaphy with vaginal mesh therapy in the management of POP. The data sources were selected for their reputation in publishing high-quality research in urology and women’s health, including PubMed, Google Scholar, ScienceDirect, and the Cochrane Library, covering publications from 2014 to 2024. We included both randomized and non-randomized studies comparing anterior colporrhaphy with vaginal mesh therapy for stress urinary incontinence (SUI), ensuring a comprehensive review of the available evidence. Data were extracted on sample size, study location, surgical technique, patient satisfaction, reoperation rates, mesh erosion, pain, sexual function, operative time, length of hospital stay, and other complications. A total of 3,528 articles were collected. After removing 2,834 duplicates, 694 unique records remained. Following a quality assessment, six studies met the final inclusion criteria. Analysis of randomized controlled trials and cohort studies revealed no significant differences between the two procedures in terms of erosion rates, SUI incidence, reoperation rates, or patient satisfaction. These findings highlight the importance for urogynecologists to carefully consider patient identification, selection, comorbidities, and the choice of POP repair procedure.
Correlation of Soil Contamination and Incident of STH Infection in Sukokerto Village Sukowono District Jember Regency Hermansyah, Bagus; Armiyanti, Yunita; Utami, Wiwien Sugih; Rahmi, Aulya; Aziz, Ayu Munawaroh
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.18731

Abstract

The most common worm infections are those caused by soil-transmitted helminths (STH) infection. Soil contamination is one of the causes of helminth transmission to humans. Poor environmental sanitation and personal hygiene facilitate the spread and transmission of STH. Jember is a district where the majority of the population lives in rural areas with poor sanitation access. This study aims to determine the correlation between soil contamination and incident of STH infection in Sukokerto Village, Sukowono District, Jember Regency. This cross-sectional analytic observational study was conducted from August 2022 to February 2023. The total of samples in this study was 44 fecal and soil around the house. The data obtained from the laboratory examination showed that the total fecal positive of STH was 11 or 25%, and soil was 13 or 29.5%. The results of the Chi-Square test analysis obtained ρ<0.05 (ρ=0.036, OR=4,457). The results showed a significant relationship between soil contamination and the incidence of STH infection in Sukokerto Village, Sukowo District, Jember Regency
Determinant of Water Source Contamination by Soil Transmitted Helminths in Rural Areas of Jember District Armiyanti, Yunita; Mash’ab Zirrun Al-Qomah; Angga Mardro Raharjo; Bagus Hermansyah; Wiwien Sugih Utami
BKM Public Health and Community Medicine The 12th UGM Public Health Symposium
Publisher : Universitas Gadjah Mada

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Abstract

Purpose: This study aims to identify STH eggs and larvae that contaminate water sources in rural areas of Jember and their risk factors. Method: This type of study is an observational analytic study with a cross-sectional approach. Samples from water sources in Mumbulsari and Sukowono districts were taken on inclusion criteria under flotation and sedimentation methods and totaled 56 samples. Respondents were interviewed on account of risk factors related to the presence of STH in water sources using a questionnaire and a total of 56 respondents. Result: The results showed that the common type of STH found was Hookworm (92.31%). The most polluted water source is river (53.84%). Based on the characteristics, the majority of respondents are female (67.86%), aged over 40 years (58.93%), have low education (57.15%), and have no job (51.79%). Found a relationship using chi-square between bowel habits and the presence of STH eggs and larvae (ρ > 0.05). Conclusion: This study proved that STH eggs and larvae can contaminate water sources such as rivers and wells The contamination is related to the habit of defecating not in latrines, so the important prevention for STH infection in water sources is to change the habit of defecation into a healthy habit.
Potensi Antimalaria Fraksi-Fraksi Daun Kembang Bulan (Tithonia diversifolia [Hemsley] A. Gray) Nuri; Wicaksono, Yudi; Rahardi, Verdian; Utami, Wiwien Sugih; Armiyanti, Yunita
Journal of Agropharmacy Vol. 1 No. 1 (2024)
Publisher : Faculty of Pharmacy, University of Jember

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Abstract

Kembang bulan (Tithonia diversifolia [Hemsley] A. Gray) has been used in traditional medicine to treat malaria. Previous research results showed that the ethanol extract of kembang bulan leaves had antimalarial activity in vivo with an ED50 of 113.39 mg/kgBW. Until now, the compounds with antimalarial activity in vivo are unknown. The initial stage that can be done to separate the compounds in the extract is fractionation. This study aims to separate the extract into fractions and test its antimalarial activity. Fractionation was carried out using a vacuum liquid chromatography method using a stationaryphase of silica gel GF254 and a mobile phase of n-hexane, chloroform and methanol in a gradient. In vivo antimalarial activity was tested using the Peter test method. Fractionation produces 5 fractions, each yield is 1.9; 2.1; 17.6; 60.8, and 17.6% respectively for fractions 1-5. The results of the antimalarial activity test for fractions 1-5 with a dose of 2 mg/kgBW showed inhibition of the growth of Plasmodium berghei respectively at 52.3 ± 1.4; 83.5±1.4; 74.6±1.2; 69.5±0.9; 44.8 ± 0.3%. Fraction 2 with the greatest resistance was tested further and showed an ED50 value of 0.52 mg/kgBW.
Spatial analysis of tuberculosis cases among stunted toddlers in Rambipuji District, Jember Regency Utami, Wiwien Sugih; Amrina, Adinda Putri Yusri; Armiyanti, Yunita; Maududie, Achmad
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art8

Abstract

Background: The ongoing prevalence of tuberculosis (TB) and stunting presents significant health challenges, frequently localized within specific regions of Indonesia. Spatial analysis is essential in controlling infectious diseases like TB, as it identifies disease clusters and patterns of local TB spread within an area. Objective: This study aimed to analyze the distribution of TB cases among stunted children through spatial analysis. Methods: We used a cross-sectional analytical descriptive study. We interviewed parents of stunted children using a questionnaire. The diagnosis of TB was made based on the pediatric TB scoring table. Coordinate data of sample sites were obtained using a Geographic Information System (GIS), supported by risk factor analysis of TB. We then created a disease distribution map using the spatial analysis by Moran's Index and Nearest Neighbor Index (NNI) methods. Results: There were 15 childhood TB cases (8.2%) among stunted children in Rambipuji District. The spatial autocorrelation test using Moran's index showed that TB cases were clustered in Rambigundam village (Moran’s index 0.2364, p-value <0.05 and Z-score >1.96). The results of the NNI analysis showed dispersed results (p-value=0.000) in all villages. Conclusion: The distribution of childhood TB cases among stunted children in Rambipuji District is primarily random, except for Rambigundam Village, which shows a clustering of cases. According to the NNI methods, childhood TB cases among stunted children are spreading throughout all villages. These results underscore the need for initiatives to curb TB transmission, especially among stunted children, which should be targeted at all villages.
The Relationship between Sanitation and Personal Hygiene with Seroprevalence of Toxoplasmosis in Pregnant Women at Kaliwates and Banjarsengon Community Health Centers Nabila Putri Anissa; Yunita Armiyanti; Eny Nurmaida; Bagus Hermansyah; Erma Sulistyaningsih; Wiwien Sugih Utami
Journal of Agromedicine and Medical Sciences Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Jember

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Abstract

Toxoplasmosis is an infectious disease in animals that can be transmitted to humans. Sanitation and personal hygiene are risk factors for toxoplasmosis. Toxoplasmosis can be transmitted from pregnant women to their fetuses. Toxoplasmosis in pregnancy can cause pregnancy, premature birth, and congenital toxoplasmosis. According to the Jember District Health Office in 2023, access to proper sanitation and good hygienic behavior is still low. The purpose of this study was to analyze the relationship between sanitation and individual hygiene with toxoplasmosis seroprevalence in pregnant women at the Kaliwates and Banjarsengon Health Centers. This study used a crosssectional study type. The subjects of the study were 65 pregnant women at the Kaliwates and Banjarsengon Health Centers who were taken using the accidental sampling technique. The serological examination used the Toxoplasma IgM and IgG ELISA kit from Calbiotech®. The results of this study showed that 77% of pregnantwomen were detected positive for toxoplasmosis. The majority of pregnant women have good sanitation and personal hygiene categories of 87.7% and 90.8%, respectively. Based on the results of Fisher's exact test, sanitation and personal hygiene are not related to toxoplasmosis seroprevalence (p>0.05). This study concludes that sanitation and personal hygiene of pregnant women at the Kaliwates and Banjarsengon Health Centers are not significantly related to toxoplasmosis seroprevalence.  
Analysis of Risk Factors and Quality of Antenatal Care (ANC) in Pregnant Women with Preeclamsia in Ajung District, Jember Regency tunsiah, tunsiah; Utami, Wiwien Sugih
Journal of Agromedicine and Medical Sciences Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i3.53772

Abstract

In 2023 and 2024 Jember Regency had the highest maternal mortality rate (MMR) in East Java. Preeclampsia (PE), a form of hypertension during pregnancy, is the second leading cause of MMR after postpartum hemorrhage. This study aimed to analyze the risk factors and quality of antenatal care (ANC) for pregnant women with preeclampsia at the Ajung Community Health Center in Jember Regency. The study employed a retrospective cohort design. The study sample consisted of 55 pregnant women with preeclampsia from the Ajung Community Health Center between 2020 and May 2025. . A two-sample independent t-test was used to analyze differences in risk factors among women with preeclampsia statistically. An ordinal regression test determined the relationship between preeclampsia risk factors and ANC quality. The results revealed 49 cases of preeclampsia occurring at or after 34 weeks of gestation and six cases occurring before 34 weeks. A significant difference was found in maternal age as a risk factor for preeclampsia. Most of the ANC quality in the study sample was very poor (62.5%), with maternal age and mean arterial pressure (MAP) being the main influencing factors. Age-related risk factors differed among pregnant women with preeclampsia and a relationship was found between maternal age, MAP, and ANC quality.
High Toxoplasmosis Seroprevalence and Anemia Among Early-Mid Pregnant Women in Jember, Indonesia Wulandari, Lindi Priyantika Tri; Armiyanti, Yunita; Aziz, Ayu Munawaroh; Hermansyah, Bagus; Sulistyaningsih, Erma; Utami, Wiwien Sugih
Journal of Community Medicine and Public Health Research Vol. 6 No. 2 (2025): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v6i2.68484

Abstract

Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii, which can be transmitted through various routes. Toxoplasmosis in pregnant women may cause abortion and fetal disabilities. Decreased body immunity due to anemia can increase the risk of toxoplasmosis during pregnancy. The purpose of this study was to identify the characteristics of pregnant women and their association with anemia, determine the prevalence of anemia and toxoplasmosis infection in pregnant women, and investigate whether anemia is a risk factor for toxoplasmosis in pregnant women. This research is an analytical, observational study using a cross-sectional laboratory examination. The sample in this study consisted of blood collected from first- and second-trimester pregnant women at the Kaliwates and Banjarsengon Public Health Centers for hemoglobin analysis and toxoplasmosis serology. Accidental sampling was conducted from July to December 2024. The research data were presented in tabular form and analyzed using the Chi-square test. This study was conducted on 65 pregnant women. The number of pregnant women with anemia was 43% and the number of pregnant women who were positive for toxoplasmosis was 66%. A significant association exists between gestational age and anemia (p-value = 0,041). Bivariate analysis between anemia and T. gondii infection showed no significant association (p-value = 0.182). This study concludes that anemia is not proven to be a risk factor for toxoplasmosis infection in pregnant women. However, the cases of anemia and toxoplasmosis were high and require specific attention.
Combination Therapy for Cryptosporidiosis in Immunocompromised Patients: A Systematic Review Utami, Wiwien Sugih; Rozaq, M.S. Irham; Indreswari, Laksmi; Abrori, Cholis; Hermansyah, Bagus
Folia Medica Indonesiana Vol. 60, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Cryptosporidium sp. is a gastroenteritis-causing pathogen that may increase mortality and morbidity in immunocompromised patients. Diarrhea is a common problem among acquired immunodeficiency syndrome (AIDS) patients, with 30–60% of patients in developed countries and 90% in developing countries affected. The prevalence of cryptosporidiosis is 3–5% of the global population, with 14.42% of those affected being immunocompromised. There is currently no vaccine available to prevent cryptosporidiosis, while nitazoxanide monotherapy is ineffective in eradicating the organism in immunocompromised hosts and malnourished children. This study aimed to determine the most effective combination therapy for cryptosporidiosis in immunocompromised patients. This study used a systematic review design and implemented eligibility criteria for the literature search across PubMed, ScienceDirect, Epistemonikos, Google Scholar, Nature, Springer, and John Wiley databases. The search utilized specific keywords and Boolean operators, i.e., “Cryptosporidium,” OR “cryptosporidiosis,” AND “combination therapy,” OR “combination treatment,” AND “immunocompromised.” Two cohort studies and two case reports were selected, three of which used a nitazoxanide and azithromycin combination as the intervention, whereas only one cohort study used a nitazoxanide and fluoroquinolone combination. The studies comprised 54 samples from post-kidney transplantation patients and one sample from an acute lymphoblastic leukemia (ALL) patient. The nitazoxanide and fluoroquinolone combination showed superior outcomes than the nitazoxanide and azithromycin combination. The stool clearance was significantly lower with nitazoxanide monotherapy than the nitazoxanide and fluoroquinolone combination (OR=0.65, 95% CI=0.34–0.92, p=0.01). However, it was non-significantly lower with the nitazoxanide and azithromycin combination compared to monotherapy (OR=0.27, 95% CI=0.01–5.77, p=0.24). Nitazoxanide monotherapy exerted a significantly lower effect than the nitazoxanide and fluoroquinolone combination in stopping diarrhea symptoms (OR=0.45, 95% CI=0.21–0.81, p=0.004). In conclusion, a combination therapy using nitazoxanide and fluoroquinolone for cryptosporidiosis in immunocompromised patients offers more favorable outcomes compared to monotherapy, particularly in stopping diarrhea and enhancing stool clearance.
Co-Authors Achmad Maududie Achmad Nazalal Furqon Adella Bintang Saputri Adinda Putri Yusri Amrina Amrina, Adinda Putri Yusri Angga Mardro Raharjo Anita Dewi Prahastuti Sujoso, Anita Dewi Prahastuti Ardyansyah, Rizky Robeth Arina, Yuliana Mahdiyah Daat Aris Prasetyo Asis Fitriana Aulya Rahmi Ayundasari, Asti Ayundasari, Asti Azham Purwandhono Aziz, Ayu Munawaroh Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bambang Ilamto Baskoro Adi Prayitno Brillian Adexa Yudinda Cholis Abrori, Cholis Devita Prima Nurmasari Dewi Rokhmah Dian Eka Putri Harnandhari Diana Chusna Mufida Dicky Setiawan Dini Agustina Dita Diana Parti Drajad, Rahadinda Mutia Dhamar Dwi Prijatmoko Dwita Aryadina Rachmawati Elvia Rahmi Marga Putri ENNY SUSWATI Eny Nurmaida Epafroditus Sanjaya Adiguna Erfan Efendi Erisadana, Rifaldy Nabiel Erma Sulistyaningsih Erma Sulistyaningsih Faizatun Nikmah, Faizatun Febrianti, Zahrah Ghaiska Najma Amnur Hanu Neda Septian Heni Fatmawati Hermansyah, Bagus Ida Srisurani Wiji Astuti Ika Barokah Suryaningsih Ika Rahmawati Sutejo Ika Rahmawati Sutejo Ika Sriwinarti Irawan Fajar Kusuma Isa Ma'rufi Isa Ma’rufi Jauhani, M. Afiful Jauhar Firdaus Kesy Sasta Handani Khoiruddin, Mukhammad Arif Hadi Kristianningrum Dian Sofiana Laily Nurhayati Laksmi Indreswari Laksmi Indreswari Leersia Yusi Ratnawati M. Ali Shodikin M.S. Irham Rozaq Mash’ab Zirrun Al-Qomah Mauliya Sri Sukmawati Wahyudi Muhammad Afiful Jauhani Muhammad Afiful Jauhani Muhammad Afiful Jauhani Muhammad Zainul Fikri Mukhammad Arif Hadi Khoirudin Nabila Putri Anissa Nanda Nuramna Nanik Kurniati Nanik Kurniyati Nidia Nursafitri Nindya Shinta Rumastika Nur Hasyimiyyah Nuri Nurmaida, Eny Nurmaida, Eny Nurus Saffana Yulianto Pangestu, Ahmad Yudho Hadi Pradana, Tasya Lukita Cyndi Pralampita, Pulong Wijang Prriantono, Dwinda Pungky Setya Arini Putra, Muhamad Dwi Eka Rachmawati, Dwita Aryadina Rahardi, Verdian Rahardjo, Angga Mardro Rahmi, Aulya Ramadanti, Novi Awalia Ramadanti, Novi Awalia Ramadhani, Rafindra Ratnawati, Leersia Yusi Rena Normasari Rozaq, M.S. Irham Sa'bani, Begawan Salsabilla, Safira Putri Nur Selly Silfana Liensa Sugeng Winarso Sulistyaningsih, Erma Supranoto, Yehuda Tri Nugroho Syamsuddin, Alif Fazduani Tartila, Jasmine Tohari, Achmad Ilham tunsiah, tunsiah Widjaja Putra, Bayu Taruna Wulandari, Lindi Priyantika Tri Yoga Setyo Yudha Nurdian Yudi Wicaksono Yunita Armianti Yunita Armiyanti Zulaikha Rizqina Rahmawati