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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sain Veteriner Jurnal Kesehatan Lingkungan indonesia e-Journal Pustaka Kesehatan Althea Medical Journal Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Jurnal Berkala Epidemiologi Folia Medica Indonesiana Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) The Indonesian Journal of Occupational Safety and Health UNEJ e-Proceeding Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner Hearty : Jurnal Kesehatan Masyarakat J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Journal of Health Sciences ARTERI : Jurnal Ilmu Kesehatan MAHESA : Malahayati Health Student Journal Solo Journal of Anesthesi, Pain and Critical Care JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat Jember Medical Journal (JMJ) Indonesian Journal of Biomedicine and Clinical Sciences Journal of Agropharmacy

Wiwien Sugih Utami

Department Of Parasitology, Faculty Of Medicine, Universitas Of Jember, Jember 68121, Indonesia

Author-ID : 2673376

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Potensi Antimalaria Fraksi-Fraksi Daun Kembang Bulan (Tithonia diversifolia [Hemsley] A. Gray) Nuri; Yudi Wicaksono; Verdian Rahardi; Wiwien Sugih Utami; Yunita Armiyanti
Journal of Agropharmacy Vol. 1 No. 1 (2024)
Publisher : Faculty of Pharmacy, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Kembang bulan (Tithonia diversifolia [Hemsley] A. Gray) has been used in traditional medicine to treat malaria. Previous research results showed that the ethanol extract of kembang bulan leaves had antimalarial activity in vivo with an ED50 of 113.39 mg/kgBW. Until now, the compounds with antimalarial activity in vivo are unknown. The initial stage that can be done to separate the compounds in the extract is fractionation. This study aims to separate the extract into fractions and test its antimalarial activity. Fractionation was carried out using a vacuum liquid chromatography method using a stationaryphase of silica gel GF254 and a mobile phase of n-hexane, chloroform and methanol in a gradient. In vivo antimalarial activity was tested using the Peter test method. Fractionation produces 5 fractions, each yield is 1.9; 2.1; 17.6; 60.8, and 17.6% respectively for fractions 1-5. The results of the antimalarial activity test for fractions 1-5 with a dose of 2 mg/kgBW showed inhibition of the growth of Plasmodium berghei respectively at 52.3 ± 1.4; 83.5±1.4; 74.6±1.2; 69.5±0.9; 44.8 ± 0.3%. Fraction 2 with the greatest resistance was tested further and showed an ED50 value of 0.52 mg/kgBW.

E-Presence Application Increases the Level of Health Personnel Discipline to Improve the Quality of Health Services in Hospitals (Systematic Review Paper) Bambang Ilamto; Dewi Rokhmah; Dwi Prijatmoko; Wiwien Sugih Utami
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.15362

ABSTRACT In the era of increasingly advanced digital technology development, the government in Indonesia uses the E-presence digital attendance application to make attendance easier for its health workers. The use of e-presence is a form of progress in information technology in government. It is necessary to research changes in the level of discipline of health workers in implementing E-presence so that it can improve the quality of service or even reduce the quality of service. Find out how the use of E-presence among health workers can improve work discipline and improve service quality. The research design in this article uses descriptive qualitative research with data originating from the results of systematic reviews from various relevant national journal sources. Articles were obtained from Google Scholar and PubMed with identification in 2023 via Google Scholar n=205 and PubMed n=80. National and International Articles. With the keywords "Digital E-Presence", "Discipline Level", "Service Quality", "Attendance", "Android", "QR Code", and "Discipline". Penelusuran artikel penelitian di tahun 2023 menggunakan kata kunci pada database (n=285). Dilakukan skrining berdasarkan kriteria inklusi dan ekslusi, dan menghasilkan 9 artikel penelitian yang layak sesuai dengan kriteria. This research has changed the motivation of health workers where the level of discipline of health workers has increased and their orientation towards achievement has also improved. The use of e-presence has the impact of increasing the quality of service in hospitals because health workers are present to serve patients on time. Keywords: Health Personnel, The Quality Of Health, Services In Hospitals

Combination Therapy for Cryptosporidiosis in Immunocompromised Patients Wiwien Sugih Utami; M.S. Irham Rozaq; Laksmi Indreswari; Cholis Abrori; Bagus Hermansyah
Folia Medica Indonesiana Vol. 60 No. 4 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v60i4.60340

Cryptosporidium sp. is a gastroenteritis-causing pathogen that may increase mortality and morbidity in immunocompromised patients. Diarrhea is a common problem among acquired immunodeficiency syndrome (AIDS) patients, with 30–60% of patients in developed countries and 90% in developing countries affected. The prevalence of cryptosporidiosis is 3–5% of the global population, with 14.42% of those affected being immunocompromised. There is currently no vaccine available to prevent cryptosporidiosis, while nitazoxanide monotherapy is ineffective in eradicating the organism in immunocompromised hosts and malnourished children. This study aimed to determine the most effective combination therapy for cryptosporidiosis in immunocompromised patients. This study used a systematic review design and implemented eligibility criteria for the literature search across PubMed, ScienceDirect, Epistemonikos, Google Scholar, Nature, Springer, and John Wiley databases. The search utilized specific keywords and Boolean operators, i.e., “Cryptosporidium,” OR “cryptosporidiosis,” AND “combination therapy,” OR “combination treatment,” AND “immunocompromised.” Two cohort studies and two case reports were selected, three of which used a nitazoxanide and azithromycin combination as the intervention, whereas only one cohort study used a nitazoxanide and fluoroquinolone combination. The studies comprised 54 samples from post-kidney transplantation patients and one sample from an acute lymphoblastic leukemia (ALL) patient. The nitazoxanide and fluoroquinolone combination showed superior outcomes than the nitazoxanide and azithromycin combination. The stool clearance was significantly lower with nitazoxanide monotherapy than the nitazoxanide and fluoroquinolone combination (OR=0.65, 95% CI=0.34–0.92, p=0.01). However, it was non-significantly lower with the nitazoxanide and azithromycin combination compared to monotherapy (OR=0.27, 95% CI=0.01–5.77, p=0.24). Nitazoxanide monotherapy exerted a significantly lower effect than the nitazoxanide and fluoroquinolone combination in stopping diarrhea symptoms (OR=0.45, 95% CI=0.21–0.81, p=0.004). In conclusion, a combination therapy using nitazoxanide and fluoroquinolone for cryptosporidiosis in immunocompromised patients offers more favorable outcomes compared to monotherapy, particularly in stopping diarrhea and enhancing stool clearance.

Hubungan Infeksi Soil-Transmitted Helminths (STH) dengan Angka Kejadian Tuberculosis (TB) pada Balita Stunting di Kecamatan Rambipuji Ayundasari, Asti; Hermansyah, Bagus; Nurmaida, Eny; Utami, Wiwien Sugih; Armiyanti, Yunita; Sulistyaningsih, Erma
Jurnal Kesehatan Andalas Vol 13, No 2 (2024): July 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i2.2386

Infection is one of the factors associated with stunting. The relationship between stunting and infection can have reciprocal effects. Stunting can increase the risk of infection. Conversely, infections such as Soil-Transmitted Helminths (STH) and Mycobacterium tuberculosis (M. tuberculosis) can also increase the risk of stunting. Objective: To analyzed the correlation between STH infection and the incidence of tuberculosis (TB) in stunting toddlers. Methods: The subjects of this study were 108 stunting toddlers obtained from a simple random sampling method. It was conducted from May 2023 to March 2024 in several villages within the Rambipuji District of Jember Regency, including Gugut, Rambigundam, Pecoro, and Kaliwining. The statistical analysis used in this study was the contingency coefficient test. Results: Findings revealed that the occurrence of STH infection with TB in stunting toddlers was 0%. Conclusion: There is no statistically significant relationship between STH infection and the incidence of TB in stunting toddlers in the Rambipuji District, Jember Regency.Keywords: soil-transmitted helminths, tuberculosis, stunting

Spatial analysis of tuberculosis cases among stunted toddlers in Rambipuji District, Jember Regency Wiwien Sugih Utami; Adinda Putri Yusri Amrina; Yunita Armiyanti; Achmad Maududie
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art8

Background: The ongoing prevalence of tuberculosis (TB) and stunting presents significant health challenges, frequently localized within specific regions of Indonesia. Spatial analysis is essential in controlling infectious diseases like TB, as it identifies disease clusters and patterns of local TB spread within an area. Objective: This study aimed to analyze the distribution of TB cases among stunted children through spatial analysis. Methods: We used a cross-sectional analytical descriptive study. We interviewed parents of stunted children using a questionnaire. The diagnosis of TB was made based on the pediatric TB scoring table. Coordinate data of sample sites were obtained using a Geographic Information System (GIS), supported by risk factor analysis of TB. We then created a disease distribution map using the spatial analysis by Moran's Index and Nearest Neighbor Index (NNI) methods. Results: There were 15 childhood TB cases (8.2%) among stunted children in Rambipuji District. The spatial autocorrelation test using Moran's index showed that TB cases were clustered in Rambigundam village (Moran’s index 0.2364, p-value <0.05 and Z-score >1.96). The results of the NNI analysis showed dispersed results (p-value=0.000) in all villages. Conclusion: The distribution of childhood TB cases among stunted children in Rambipuji District is primarily random, except for Rambigundam Village, which shows a clustering of cases. According to the NNI methods, childhood TB cases among stunted children are spreading throughout all villages. These results underscore the need for initiatives to curb TB transmission, especially among stunted children, which should be targeted at all villages.

Soil-Transmitted Helminth Infection and Macronutrient Intake among Stunted Toddlers in Panti Sub-district, Jember Ghaiska Najma Amnur; Yunita Armiyanti; Irawan Fajar Kusuma; Leersia Yusi Ratnawati; Wiwien Sugih Utami; Bagus Hermansyah
Media Gizi Indonesia Vol. 20 No. 1 (2025): MEDIA GIZI INDONESIA (NATIONAL NUTRITION JOURNAL)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgi.v20i1.74-80

Soil-transmitted helminth (STH) infections are one of the most common infectious diseases in the developing world, with prevalence rates as high as 65%. STH infections generally affect the digestive system, which can reduce appetite and nutrient absorption. This study aimed to determine the association between STH infection and macronutrient intake in stunted toddlers aged 12-36 months in Panti Sub-district, Jember Regency. This study used observational analysis method with cross-sectional approach. The total number of subjects was 83 stunted toddlers. Data on STH infection were collected through fecal examination and 2x24 hour food recall questionnaire to assess their macronutrient intake. The results of the study showed that the prevalence of STH was 4.8% with species identified in the examinations such as Ascaris lumbricoides (2.4%) and hookworm (2.4%). The majority of macronutrient intake was considered sufficient for protein (77.1%), deficit for carbohydrate (94%) and fat (77.1%). Bivariate analysis using the contingency coefficient correlation test showed that there was no significant correlation between STH infection and macronutrient intake. Based on the results of this study, macronutrient intake may be influenced by other factors such as the role of parents in preparing nutritious food, economic status, and mild degree of infection. However, the underlying mechanism remains unclear and should be further investigated.

Hubungan Infeksi Soil-Transmitted Helminths (STH) dengan Angka Kejadian Tuberculosis (TB) pada Balita Stunting di Kecamatan Rambipuji Ayundasari, Asti; Hermansyah, Bagus; Nurmaida, Eny; Utami, Wiwien Sugih; Armiyanti, Yunita; Sulistyaningsih, Erma
Andalas Journal of Health Vol. 13 No. 2 (2024): July 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v13i2.2386

Stigma Tuberkulosis Paru di Asia Tenggara: Systematic Literatur Review Pradana, Tasya Lukita Cyndi; Widjaja Putra, Bayu Taruna; Utami, Wiwien Sugih
MAHESA : Malahayati Health Student Journal Vol 5, No 6 (2025): Volume 5 Nomor 6 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i6.18337

ABSTRACT Pulmonary tuberculosis is an infectious disease that remains a global health problem. Tuberculosis stigma is determinants of this disease. The purpose of this study was to find out the determinants of tuberculosis stigma in 4 Southeast Asian regions, namely Thailand, Cambodia, Vietnam and Indonesia. The research method used was a systematic literature review using PRISMA guidelines. From the 14 articles reviewed, it was found that tuberculosis stigma can be divided into two things, namely personal and negative views of the surrounding community. The impact of stigma is that patients choose to isolate themselves, feel embarrassed, and are discriminated against by the surrounding community. The stigma of tuberculosis in four regions make the problem of tuberculosis tend to be high. The author recommends providing education to communities that stigmatize tuberculosis patients. By providing education, the author hopes that the community can change their mindset and provide social support to tuberculosis patients. Keywords: Tuberculosis Stigma, Systematic Literatur Review, Southeast Asia. ABSTRAK Tuberkulosis paru merupakan penyakit menular yang masih menjadi masalah kesehatan di seluruh dunia. Salah satu faktor determinan dari penyakit ini dan adalah stigma tuberkulosis. Tujuan dari penelitian ini mencari tahu faktor determinan stigma tuberkulosis di 4 wilayah Asia Tenggara yaitu Thailand, Kamboja, Vietnam, dan Indonesia. Metode penelitian yang digunakan adalah systematic literatur review dengan pedoman PRISMA. Dari 14 artikel yang direview didapatkan bahwa stigma tuberkulosis dibedakan menjadi dua hal yaitu personal dan pandangan negatif masyarakat sekitar. Dampak yang ditimbulkan dari stigma yaitu pasien memilih untuk mengisolasi diri, merasa malu, dan terdiskriminasi dari lingkungan sekitar. Adanya stigma tuberkulosis di empat wilayah tersebut menjadikan masalah tuberkulosis cenderung tinggi. Penulis merekomendasikan pemberian edukasi pada masyarakat yang memberikan stigma kepada pasien tuberkulosis. Dengan adanya upaya pemberian edukasi, penulis berharap masyarakat dapat merubah pola pikir dan memberi dukungan sosial kepada pasien tuberkulosis. Kata Kunci: Stigma Tuberkulosis, Systematic Literatur Review, Asia Tenggara

The Relationship between Knowledge and Attitude of Slaughterhouse Workers in Relation with Cattles' Fascioliasis as an Effort to Prevent Halzoun Syndrome in Jember Hermansyah, Bagus; Salsabilla, Safira Putri Nur; Febrianti, Zahrah; Utami, Wiwien Sugih; Armiyanti, Yunita
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.102910

Prevalensi fascioliasis pada sapi di Jember mencapai 56,6%, sehingga berpotensi menimbulkan kerugian ekonomi di Indonesia sekitar 6,9 miliar rupiah. Mengonsumsi hati sapi mentah atau setengah matang yang terkontaminasi cacing Fasciola spp. dewasa dapat menyebabkan sindrom halzoun, yaitu reaksi hipersensitivitas yang mengenai mukosa bukafaring dan saluran pernapasan atas. Pencegahan sindrom halzoun yang efektif memerlukan penerapan prinsip “ASUH” oleh pekerja rumah potong hewan, yang harus memiliki pengetahuan yang baik dan sikap proaktif terhadap tugasnya. Penelitian ini bertujuan untuk mengkaji hubungan antara pengetahuan dan sikap pekerja rumah potong hewan dengan prevalensi fascioliasis pada sapi sebagai upaya pencegahan sindrom halzoun di Jember. Desain penelitian yang digunakan adalah cross-sectional, dengan pengumpulan data dilakukan pada 35 pekerja di 9 rumah potong hewan di Jember pada bulan Agustus sampai dengan Desember 2024. Analisis menggunakan Uji Fisher's Exact. Hasil analisis menunjukkan nilai p untuk pengetahuan dan sikap terhadap fascioliasis pada sapi masing-masing adalah p=0,103 dan p=0,592. Kesimpulan dari penelitian ini adalah tidak terdapat hubungan yang signifikan antara pengetahuan dan sikap petugas rumah potong hewan dengan prevalensi fascioliasis pada sapi sebagai upaya pencegahan sindrom halzoun di Jember.

Comparison of anterior colporrhaphy and vaginal mesh therapy for pelvic organ prolapse: a systematic review and meta-analysis Mukhammad Arif Hadi Khoirudin; Nidia Nursafitri; Mauliya Sri Sukmawati Wahyudi; Muhammad Zainul Fikri; Dita Diana Parti; Wiwien Sugih Utami; Dian Eka Putri Harnandhari
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 3 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i3.19977

Pelvic organ prolapse (POP) is a common pelvic disorder among women. Although it is not life-threatening, POP represents significant health concern because it can cause urinary incontinence, decrease sexual function, and impair quality of life. This systematically review was conducted to compare the effectiveness and safety of anterior colporrhaphy with vaginal mesh therapy in the management of POP. The data sources were selected for their reputation in publishing high-quality research in urology and women’s health, including PubMed, Google Scholar, ScienceDirect, and the Cochrane Library, covering publications from 2014 to 2024. We included both randomized and non-randomized studies comparing anterior colporrhaphy with vaginal mesh therapy for stress urinary incontinence (SUI), ensuring a comprehensive review of the available evidence. Data were extracted on sample size, study location, surgical technique, patient satisfaction, reoperation rates, mesh erosion, pain, sexual function, operative time, length of hospital stay, and other complications. A total of 3,528 articles were collected. After removing 2,834 duplicates, 694 unique records remained. Following a quality assessment, six studies met the final inclusion criteria. Analysis of randomized controlled trials and cohort studies revealed no significant differences between the two procedures in terms of erosion rates, SUI incidence, reoperation rates, or patient satisfaction. These findings highlight the importance for urogynecologists to carefully consider patient identification, selection, comorbidities, and the choice of POP repair procedure.

Co-Authors Achmad Ilham Tohari Achmad Maududie Achmad Nazalal Furqon Adella Bintang Saputri Adinda Putri Yusri Amrina Adinda Putri Yusri Amrina Angga Mardro Raharjo Angga Mardro Raharjo Anita Dewi Prahastuti Sujoso, Anita Dewi Prahastuti Ardyansyah, Rizky Robeth Arina, Yuliana Mahdiyah Daat Aris Prasetyo Asis Fitriana Aulya Rahmi Ayundasari, Asti Ayundasari, Asti Azham Purwandhono Aziz, Ayu Munawaroh Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bambang Ilamto Baskoro Adi Prayitno Brillian Adexa Yudinda Cholis Abrori, Cholis Devita Prima Nurmasari Dewi Rokhmah Dian Eka Putri Harnandhari Diana Chusna Mufida Dicky Setiawan Dini Agustina Dita Diana Parti Drajad, Rahadinda Mutia Dhamar Dwi Prijatmoko Dwita Aryadina Rachmawati Elvia Rahmi Marga Putri ENNY SUSWATI Epafroditus Sanjaya Adiguna Erfan Efendi Erma Sulistyaningsih Erma Sulistyaningsih Faizatun Nikmah, Faizatun Febrianti, Zahrah Ghaiska Najma Amnur Hanu Neda Septian Heni Fatmawati Hermansyah, Bagus Ida Srisurani Wiji Astuti Ika Barokah Suryaningsih Ika Rahmawati Sutejo Ika Rahmawati Sutejo Ika Sriwinarti Irawan Fajar Kusuma Isa Ma'rufi Isa Ma’rufi Jauhani, M. Afiful Jauhar Firdaus Kesy Sasta Handani Khoiruddin, Mukhammad Arif Hadi Kristianningrum Dian Sofiana Laily Nurhayati Laksmi Indreswari Laksmi Indreswari Laksmi Indreswari Leersia Yusi Ratnawati M. Ali Shodikin M.S. Irham Rozaq Mash’ab Zirrun Al-Qomah Mauliya Sri Sukmawati Wahyudi Mei Syafriadi Muhammad Afiful Jauhani Muhammad Afiful Jauhani Muhammad Afiful Jauhani Muhammad Zainul Fikri Mukhammad Arif Hadi Khoirudin Nanda Nuramna Nanik Kurniati Nanik Kurniyati Nidia Nursafitri Nindya Shinta Rumastika Nur Hasyimiyyah Nuri Nurmaida, Eny Nurmaida, Eny Nurus Saffana Yulianto Pangestu, Ahmad Yudho Hadi Pradana, Tasya Lukita Cyndi Pralampita, Pulong Wijang Prriantono, Dwinda Pungky Setya Arini Putra, Muhamad Dwi Eka Rachmawati, Dwita Aryadina Rahardjo, Angga Mardro Ramadanti, Novi Awalia Ramadhani, Rafindra Ratnawati, Leersia Yusi Rena Normasari Rifaldy Nabiel Erisadana Rini Riyanti Rondhianto Rondhianto Sa'bani, Begawan Salsabilla, Safira Putri Nur Selly Silfana Liensa Sugeng Winarso Sulistyaningsih, Erma Syamsuddin, Alif Fazduani Tartila, Jasmine Verdian Rahardi Widjaja Putra, Bayu Taruna Winda Cindy Wulandari Yehuda Tri Nugroho Supranoto Yoga Setyo Yudha Nurdian Yudi Wicaksono Yunita Armianti Yunita Armiyanti Yunita Armiyanti Zulaikha Rizqina Rahmawati

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