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All Journal Jurnal Penelitian Saintek Jurnal Ilmu Dasar Jurnal Matematika & Sains WIDYATAMA Pharmacon Journal of Community Services and Engagement Journal of Nutraceuticals and Herbal Medicine Jurnal Kreativitas PKM Jurnal Penyuluhan Perikanan dan Kelautan INTEGRITAS : Jurnal Pengabdian Jurnal Ners Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Proceeding of International Conference Health, Science And Technology (ICOHETECH) Journal of Pharmaceutical and Sciences. Jurnal Ilmiah Kesehatan Usadha Journal of Pharmacy Borneo Journal of Pharmacy Journal of Community Services and Engagement: Voice of Community (VOC) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Journal of Nutraceuticals and Herbal Medicine Jurnal Sains dan Kesehatan
Haryoto Haryoto
Universitas Muhammadiyah Surakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : Jurnal Ners

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Isolasi dan identifikasi ekstrak etanol biji pare Rosnah, Rosnah; Haryoto, Haryoto
Jurnal Ners Vol. 8 No. 2 (2024): OKTOBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i2.23594

Abstract

WHO telah menyarankan pengobatan herbal untuk menjaga kesehatan, mencegah, dan mengobati penyakit, terutama penyakit degeneratif seperti hiperlipidemia. Biji pare (Momordica charantia) memiliki kandungan yang diduga memiliki efek pada hiperlipidemia adalah flavonoid, saponin, dan tanin. Selain itu, biji pare mengandung senyawa kimia seperti momordisin, momordin, karantin, asam trikosanik, resin, asam resinat, saponin, vitamin A dan C, serta minyak lemak seperti asam oleat, asam linoleat, asam stearat, dan asam oleostearat. Salah satu senyawa yang dapat dijadikan sebagai antioksidan adalah flavonoid, yang mana dapat menghentikan metabolisme asam lemak dengan menghentikan enzim lipase pancreas. Tujuan penelitian ini adalah untuk menemukan kandungan senyawa pada isolat biji pare. Maserasi digunakan sebagai metode ekstraksi, fraksinasi dilakukan dengan metode partisi cair-cair, isolasi dilakukan menggunakan kromatotron, dan senyawa diidentifikasi dengan menggunakan FTIR. Berdasarkan hasil maserasi diperoleh rendemen sebesar 24,08 dan hasil fraksinasi pada masing-masing pelarut diperoleh berat fraksi etil asetat sebesar 2,92 gram dengan rendemen sebesar 2,42% dan n-heksan 3,27 gram dengan rendemen 2,71%. Hasil isolasi yang diperoleh dari satu spot FTIR menunjukkan spektrum flavonol dengan gugus karboksil pada bilangan gelombang 1737,73 cm-1.Kata Kunci: Momordica charantia, Isolasi, FTIR.AbstractWHO has recommended herbal medicine to maintain health, prevent and treat disease, especially degenerative diseases such as hyperlipidemia. Bitter melon seeds (Momordica charantia) contain ingredients that are thought to have an effect on hyperlipidemia, namely flavonoids, saponins and tannins. Apart from that, bitter melon seeds contain chemical compounds such as momordisin, momordin, quarantine, tricosanic acid, resin, resinic acid, saponin, vitamins A and C, as well as fatty oils such as oleic acid, linoleic acid, stearic acid and oleostearic acid. One compound that can be used as an antioxidant is flavonoids, which can stop fatty acid metabolism by stopping the pancreatic lipase enzyme. The aim of this research was to find the compound content in bitter melon seed isolates. Maceration was used as an extraction method, fractionation was carried out using the liquid-liquid partition method, isolation was carried out using a chromatotron, and compounds were identified using FTIR. Based on the maceration results, the yield was 24.08 and the fractionation results in each solvent showed that the weight of the ethyl acetate fraction was 2.92 grams with a yield of 2.42% and n-hexane was 3.27 grams with a yield of 2.71%. The isolation results obtained from one FTIR spot showed a flavonol spectrum with a carboxyl group at a wave number of 1737.73 cm-1.
Co-Authors A Anifatussaa'dah abdul, ahwan Abdul, Rasyid Ahwanti Rukdiatma Nur’aini Alfa Frista Amalia Suci Medisusyanti Amaliyah Dina Anggraeni Andi Suhendi Annisa Meyndra Komala Aprilianingtyas, Tri Ardalia Rinanda Oktaviani Arly Syahputri , Janies Azzahra, Hanifa Putri Bama, Samsun Ari Broto Santoso Burhanudin Ichsan Cast Torizellia Chairunnisa, Alya Cita Hanif Muflihah Diah Siwi Ardiyani Dina Ayu Amalia Dwi Bagus Pambudi Dwi Sarbini Dyah Rahmawatie Ratna Budi Utami Dyera Forestryana Erika Nuur Anisa Putri Erna Herawati Euis Holisotan Hakim Fahriza Mei Trihatmoko Faridita khoirun Nisa' Fida’ Husain Fidhia Nur Rifaini Firdaus, Gita Firstca Aulia Rachma Frida Rosenova Gita Firdaus Hafid Nugroho Hafiz Ramadhan Haliza Arzeti Nurseptiria Haya Nabilah Utama Heng Yen Khong Henggar Prasetyo Wikan Saputro Hidayah Karuniawati Ida Maesaroh Ikhsan, Maulida Nur Jalifah Latip Joko Kristianto Khusnul Khotimah Kosworo Kosworo Laila Dzafira Lia Dewi Juliawaty Lina Ayu Kusumastuti Listiana Masyita Dewi Listyana Dewi Prastiwi Lusia, Eka Mariska Sri Harlianti Marlupi Dwi Lestari Marsilia Rosa Sinensis HI maryatun maryatun Muhammad Irfan Muhammad Irfan Muhammad Priyadi Muhtadi Muhtadi Munti Sarida Niati Ambarsari Nugroho Adi Suseno Nursalinda Kusumawati Nuryanti, Yulia Dwi Nur’aini, Ahwanti Rukdiatma Peni Indrayudha Pratiwi Widowati Putri Agustina Putri, Annisa Nur Lathifah Amanda Raafika Studiviani Rahardian Surya Basusena Rizki Ainun Fitriani Rosnah, Rosnah RR. Ella Evrita Hestiandari Rusdin Rauf Saputri, Luki Rahmadani Tulus Sayyidah Nurul Muslihah Sekarsari, Devina Sendy Pradila Putri Siyama, Anis Sjamsul Arifin Achmad Suranto Suranto Suranto, Choirun Nisa Tanti Azizah Sujono Tia Mella Citra Tista Ayu Fortuna Tri Aprilianingtyas Utomo, Chandra Wahyu Vitania Marsya Widowati, Pratiwi Wildan Firdaus, Muhammad Yana Maolana Syah Yulia Dwi Nuryanti Yuliana Dwi Jayanti Yurnanda Ambar Mustika