Article Per Year (5 Year)
p-Index From 2021 - 2026
4.273
P-Index
This Author published in this journals
All Journal Medula Juke Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Indonesian Tourism, Hospitality and Recreation Jurnal Kesehatan Medica Hospitalia JURNAL PIONIR JK Unila (Jurnal Kedokteran Universitas Lampung) JOURNAL LA MEDIHEALTICO Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Farmasetis Majority JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Nurul Islamy
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 36 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Jurnal Kesehatan

 1 
Kidney Weight: The Pre-Clinical Analysis on the Influence of Probiotic Supplementation in Malnutrition Haq, Rais Amaral; Berawi, Khairun Nisa; Morfi, Chicy Widya; Islamy, Nurul
Jurnal Kesehatan Vol 16 No 3 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i3.5432

Abstract

A study showed malnutrition, encompassing both obesity and undernutrition, is a serious metabolic condition that leads to health complications, including kidney injury. Probiotics have been proposed as a potential adjuvant therapy to improve compensatory kidney function. However, research on the effects of probiotic intervention on kidney morphological changes across different nutritional statuses remains limited. This exploratory pilot study involved 24 male isogenic Sprague Dawley rats (n=24; 7-8 weeks old), which were divided into six groups (n=4): undernourished (KU), undernourished-probiotics (KU-P), normal (KN), normal-probiotics (KN-P), obese (KO), and obese-probiotics (KO-P). The rats underwent a 10-day dietary period, followed by a 44-day treatment period, and were terminated on day 45. The kidneys were then extracted and weighed using an analytical scale. Kidney weight data were analyzed using a non-parametric Kruskal-Wallis test, followed by post hoc Dwass-Steel-Critchlow-Fligner (DSCF) tests. Findings revealed a significant difference in kidney weight among the groups (p=0.001), with a substantial effect size. Descriptive trends showed that the obese (KO) group had the highest kidney weights, while the undernourished (KU) group had the lowest. The normal-probiotic group (KN-P) showed a trend toward increased kidney weight compared with the undernourished group (KU); however, conservative pairwise comparisons did not reach statistical significance (p>0.05) due to the limited sample size. Nutritional status is the primary factor influencing kidney weight. While probiotics demonstrated a corrective effect on kidney morphology in the normal group, their supplementation efficacy requires further evaluation, particularly in undernourished and obese conditions.
Co-Authors Ade Yonata Ade Yonata, Ade Afrianza Dafi Ramadhan Agustyas Tjiptaningrum Ahmad Fauzi Akhmad Yogi Pramatirta, Akhmad Yogi Alandra Rizhaqi Vastra Amillia Siddiq Arli Suryawinata Aziz, M. Alamsyah Bahmid Bambang Eko Subakti Betta Kurniawan, Betta Dani Setiawan Dhea Mutiara Karmelita Edi Kurniawan Efriyan Imantika Ety Apriliana Fiana Deswita Firmansyah Basir Fukrapti Fukrapti Hamidi, Syahrul Haq, Rais Amaral Hasan Hasan Hermie Tendean Ikhlas Taufik Indri Windarti Javinka Fairuz Zahrani Julizar Mauttaqin Khaerunnisa P, Maya Khaerunnisa, Maya Khairun Nisa Khairun Nisa Kurniawaty, Evi Kusumaningtyas, Aditya Liana Sidharti Lukman Pura Lumentut, Anastasia M. Lumentut, Anastasia Mariane M Nico Hardianto M Tomy Iskandar M. Ricky Ramadhian Maelissa, Merlin Maelissa, Merlin M. Maelissa, Merlin Margreth Mahardika Putra Mallarangeng, Andi Nafisah Tendri Adjeng Marlon Brando Miftahul Husna Morfi, Chicy Widya Muhammad Caesario Liazmi Najoan, Rizki Nur Ayu Virginia Irawati Nurmayeni Nuswil Bernolian Prabowo, Arif Yudho Puspitasari, Maya Khaerunnisa Ratna Dewi Puspita Sari Restu Krisnanda Rezita Rahma Reza Rezita Rahma Reza Rinaldy, Dino Risdianto Risdianto Riska Putri Soraya Rizki Hanriko Rodiani - Rodiani, Rodiani Rudiyanto, Waluyo Sayuti, Marzuqi Selvi Rahmawaty Setyorini Irianti Siregar, Bintang Abadi Situmorang, Ephraim Matthew Sebastian Syahrul Hamidi Nasution Taruna, Achmad Theodorus Theodorus Ustami Panjaitan Waluyo Rudiyanto Wilda Ainia Silmi Kaffah Wirawan, Wahyudi Yuska, Salsa Nurfajri Zahra Dewi Hasna Difa