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All Journal Jurnal Pendidikan Vokasi Jurnal Tata Boga Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Health Notions Jurnal Gizi Klinik Indonesia Pontianak Nutrition Journal (PNJ) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat International Journal for Educational and Vocational Studies JURNAL GIZI DAN KESEHATAN Jurnal Mitra Kesehatan Among : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Wahana Pendidikan Jurnal Gizi Masyarakat Indonesia (The Journal of Indonesian Community Nutrition) Jurnal Ilmiah Kesehatan Masyarakat Sehat Rakyat: Jurnal Kesehatan Masyarakat Jurnal Ilmu Kesehatan dan Gizi Journal of Educational Innovation and Public Health Medic Nutricia : Jurnal Ilmu Kesehatan Antigen: Jurnal Kesehatan Masyarakat dan Ilmu Gizi Inovasi Kesehatan Global Journal of Community Service (Abdisci) HARENA: Jurnal Gizi Lentera : Journal of Gender and Children Studies Jurnal Ilmiah Pendidikan Citra Bakti
Rita Ismawati
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Health Notions

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The Effect of Green Coffee Bean Extract on The Weight Rats with High Fat Diet Alristina, Arie Dwi; Adi, Annis Catur; Ismawati, Rita
Health Notions Vol 2 No 4 (2018): April 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Abstract

WHO declares that obesity is a global epidemic. In 2014, 39% of adults >18 years old were overweight and 13% had obesity. This research aims to determine the effect of green coffee extract on the weight rats fed high-fat diet. Method: This research is true experimental pre-post test with control group design. The animals were grouped into 5 groups, i.e., group1 (negative control), group2 (positive controls fed high-fat diet), group3 (high-fat diet and GCBE dose of 100 mg/kg BW), group4 (high-fat diet and GCBE with dose of 200 mg/Kg BW), group5 (high-fat diet and GCBE dose of 400 mg/Kg BW). The obtained data were tested with one-way ANOVA followed by LSD analysis with α=0.05. Results: This research proves that green coffee bean extract with a dose of 100, 200 and 400 mg/kg BW can lower weight of rats with higt fat diet. Discussion: Green coffee extract contains active compound of chlorogenic acid that can increase AMPK activity so it has positive impact that can direct the result of metabolite substance, which is useful in decreasing fat synthesis. The high fat oxidation process results in decreased fat synthesis characterized by burning fat into energy thereby decreasing fat cells in adipose tissue.
Co-Authors Ahmad Alwi Aiko Aristawati Nabila Alby Tirtaarum Hari Paraswati Alristina, Arie Dwi Alya Afirsta Rahmadani Amalia Ruhana, Amalia Amiju Sania Firda, Amar Annis Catur Adi Annisa Nur Aini Aprilianu, Dinia Asrul Bahar Beatrich Laila Siregar Chika Awalia Rachmawati Choirul Anna Nur Afifah Dini, Cleonara Yanuar Dony Perdana Endang Sri Wahjuni Erina Rahmadyanti Farkhan, M. Fatkhur Romadhoni, Ita Hidayatush Shoimah, Lutfi Hikmah, Yuniar Fitria Ingkasari Salamao Ita Fatkhur Romadhoni Lukitasari, Febriani Luthfiyah Nurlaela MARNIATI Marniati Marniati, Marniati Maya Akmilia Rachmanonny Mayasari, Noor Rohmah Mochamad Cholik MUHAJI Muhaji Muhaji Nita Kusumawati Nokiawati, Novik Nur Afifah, Choirul Anna Nurkitawangi, Rizkarina Permata, Tri Wahyuni Indah Rahayu Dewi Ramadanti, Rivana Oktavia Rohmah Mayasari, Noor Rus, Ridwan Che Salsabila Romadona Satwika Arya Pratama Siahaan, Ruth Elisa Putri Siti Sulandjari Siti Uswatun Hasanah Sri Handajani Supari Muslim Tandy, Cut Athaya Artawana TAUHIDIYAH, LINDA Tri Rijanto Veni Indrawati Wiyanto, Theodorus Zafira Ananda Neda Zuhrah, Poppy