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All Journal Jurnal Bios Logos Indonesian Journal of Medicine Jurnal Dunia Farmasi Jurnal Pengabdian Pada Masyarakat METHABDI Majalah Ilmiah METHODA Jurnal Kedokteran Methodist
Hadyanto Lim
Universitas Methodist Indonesia
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Pelatihan Penanganan Cardiac Arrest (Henti Jantung) dengan Menggunakan Metode Bantuan Hidup Dasar (BHD) Bagi Pengemudi Ojek Online Se Kota Medan Siahaan, Dwi Lunarta D. S.; Sinatra, Jadeny; Nazma, Diani; Lubis, Andriamuri P.; Tanjung, Qodri F.; Sitepu, John Frans; Hamdi, Tasrif; Hamdani, Irfan; Chalil, M. Jalaluddin A.; Yunafri, Andri; Irina, Sinta; Zainumi, Cut M.; Fadinie, Wulan; Silaen, Ester L. R.; Simbolon, Boyke M.; Siahaan, Jekson M.; Lim, Hadyanto; Anto, Endy Juli; Tobing, Paul S. M. L.; Rimbun, Surjadi; Hutasoit, Eka Samuel P.; Tambunan, Ronald T. H.; Tarigan, Juliyanti; Stephanie S., Kezia; Natalie S., Karen
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 4 No 2 (2024): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol4No2.pp188-193

Abstract

Cardiac Arrest is the leading cause of death in the world including Indonesia, which can occur anytime and anywhere. The causes vary, ranging from fatigue, and underlying health conditions, to traffic accidents. Basic Life Support (BLS) is the initial step that can be taken to restore respiratory and circulatory function in individuals experiencing respiratory or cardiac arrest. It is important for online motorcycle taxi drivers to possess these skills, as they often spend time on the road and interact with various people in different situations. Perhimpunan Dokter Spesialis Anesthesiology dan Terapi Intensif (PERDATIN) North Sumatra Branch concluded a series of Kursus Penyegar dan Penambah Ilmu Anestesia (KPPIA) by providing basic life support training to 521 public transport or online motorcycle taxi drivers in the city of Medan on September 29, 2024. Held at the Gedung Serba Guna of the North Sumatra Provincial Government, the participants were divided into 52 groups guided directly by anesthesiologist specialists as instructors. By providing this education and training, they can be better prepared to face emergency situations on the road, thereby enhancing safety and service for passengers
A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation : A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation lim, hadyanto; Hutasoit, Eka Samuel P; Endy Juli Anto
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

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Abstract

Background Recurrent Bell’s palsy is a rare condition that can affect the ipsilateral or contralateral to the affected side of the primary attack. There is still no consensus on treatment guidelines for recurrent Bell’s palsy. Therefore, we report a case of idiopathic recurrent contralateral facial palsy treated with autologous peripheral blood stem cell (PBSC) transplantation. Case Presentation A 72-year-old man presented with the sudden onset of right facial weakness, which was contralateral to the affected side of the first episode of facial palsy. The weakness had progressed with difficulty in closing the right eye, drooling the water from the right side of the mouth, and chewing impairment which was consistent with House Brackmann grade IV or moderately severe facial nerve grading system. He had exposure to cold stimulation, and a history of hypertension. He was given G-CSF 10 ug/kg/day for 5 days to mobilize stem cells, followed by apheresis on the 5th day. He did not receive acupuncture treatment. He had a complete recovery in 3 weeks with House Brackmann grade I or normal function of facial nerve. Conclusion Peripheral blood stem cell transplantation had a beneficial effect on the complete recovery of this recurrent Bell’s palsy and provides a treatment strategy in patients with unilateral facial palsy.
Pelatihan Bantuan Hidup Dasar (BHD) Bagi Jemaat Gereja HKBP Jl. Uskup Agung Sugiopranoto Medan: Upaya Peningkatan Pengetahuan dan Keterampilan Pertolongan Pertama pada Kondisi Gawat Darurat Siahaan, Dwi Lunarta D. S.; Owen Sitompul; Marolop Hutapea; Joslouis Hutagaol; Horas Rajagukguk; Rebecca Rumesty Lamtiar; Jadeny Sinatra; Alexander P. Marpaung; Novrina Situmorang; Maesstro B. U. Simanjuntak; Harry Butar-butar; Ivonne R.V.O. Situmeang; Evirosa J. Simanjuntak; Inda M. H. Sinaga; Julenda I. Sebayang; Sanggam B. Hutagalung; Irene R. T. Damanik; Adrian Khu; Hanjaya, Hanjaya; Nova Feronika Rajagukguk; Jekson M. Siahaan; Hadyanto Lim; Paul S. M. L. Tobing; Surjadi Rimbun; Ronald T. H. Tambunan; Juliyanti Tarigan; Kezia Stephanie S.; Karen Natalie S.
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

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Abstract

Sudden death due to cardiac arrest and respiratory failure frequently occurs in the community, including in public places and houses of worship. Basic Life Support (BLS) is a simple yet crucial initial action to preserve life before advanced medical care is available. This community service activity was part of the HKBP Gotilon Festival 2025, organized in collaboration between the HKBP Church Jl. Uskup Agung Sugiopranoto Medan, Medical Faculty of Universitas Methodist Indonesia, Medical Faculty of Universitas HKBP Nommensen, and supported by the Indonesian Cardiovascular Specialist Association (PERKI) as experts. The program aimed to improve the knowledge and skills of the congregation of the HKBP Church in performing BLS. The methods included health education on the basic concepts of BLS, demonstration of cardiopulmonary resuscitation (CPR), and hands-on practice using mannequins. The results showed an increase in participants understanding of emergency response steps as well as their ability to perform CPR correctly. This activity is expected to raise community awareness of the importance of BLS skills and to equip them with the capability to provide initial assistance in emergency situations.
Chronic Lumbar Radiculopathy Treated With Autologous Peripheral Blood Stem Cells: A Case Report Hadyanto Lim; AlexanderP.Marpaung; IndaM.Sinaga; Julenda Sebayang; Surjadi Rimbun; Adrian Khu
Jurnal Kedokteran Methodist Vol. 18 No. 2 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v18i2.5477

Abstract

Background : Lumbar radiculopathy may arise from the compression oflumbosacral nerve roots, leading to pain and disability. We report a caseof chronic lumbar radiculopathy that was successfully treated withperipheral blood stem cells over 24 weeks.Case Presentation : A 62-year-old woman with sharp pain in the back,radiating to both lower legs. Her pain became intense when she waswalking about 200 meters, and has been happening for 2 years. She felland hit her back 7 years ago, and refused to undergo spine surgery in ahospital. Magnetic resonance imaging revealed facet joint hypertrophyand thickening of the ligamentum flavum at L3/L4, L4/L5, and narrowingof the spinal canal. The pretreatment numerical pain rating (NPR) scorewas 7 (out of 10), and the Oswestry Disability Index (ODI) for low backpain was 19 or 38% (19/50 x100%). She was administered a 5-day courseof granulocyte colony-stimulating factor (G-CSF, 5mg/kg/day)subcutaneously, followed by leukapheresis on the fifth day. Circulatingand intravenous infusion of autologous peripheral blood stem cells wereanalyzed using flow cytometry. She also received transforaminal injectionsof 3 ml of peripheral blood stem cells (PBSCs) at each affected lumbarlevel. Peripheral blood CD34+ cells increased fro-treatment, the percentage reductions in pain and ODI were 100% and79.0%, respectively. There were no serious adverse effects from theprocedure.Conclusion: Autologous peripheral blood stem cells are an effectivetreatment for chronic lumbar radiculopathy.Keywords : lumbar radiculopathy, peripheral blood stem cells, spinalstenosis, granulocyte colony-stimulating factor, leukapheresis
Anti-inflammatory and Insulin-sensitizing Effects of Combined Pandanus amaryllifolius and Syzygium polyanthum Extracts in HFD-STZ Induced Diabetic Rats Meilinda, Selvia; Lim, Hadyanto; Anto, Endy Juli; Siahaan, Jekson M; Tarigan, Menang B
JURNAL BIOS LOGOS Vol. 16 No. 1 (2026): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v16i1.66731

Abstract

Type 2 Diabetes Mellitus (T2DM) is a global health crisis characterized by insulin resistance and pancreatic -cell failure, largely driven by chronic low-grade inflammation. Elevated pro-inflammatory markers, particularly TNF- and IL-6, disrupt insulin signaling. While conventional oral hypoglycemics are effective, their long-term use is often hindered by adverse effects. Pandanus amaryllifolius and Syzygium polyanthum are polyphenol-rich medicinal plants with significant antioxidant potential. This study evaluates the in vivo efficacy of a combined ethanolic extract of these plants in reducing TNF-, IL-6, and HOMA-IR levels, alongside in silico validation of their bioactive compounds. An experimental posttest-only control group design was employed using HFD-STZ-induced male Wistar rats. Key parameters included blood glucose, HOMA-IR, inflammatory cytokines, and pancreatic histopathology. Molecular docking was conducted to analyze the interaction between bioactive compounds and glucose metabolism receptors. The combined extracts significantly suppressed systemic inflammation, marked by a substantial reduction in TNF- and IL-6. This correlated with improved insulin sensitivity and lower HOMA-IR values. Histopathologically, the 200 mg/kg BW dose showed the most significant recovery of the islets of Langerhans. In silico analysis confirmed that flavonoids like quercetin exhibit strong binding affinities to target proteins. The combination of P. amaryllifolius and S. polyanthum acts as a potent anti-inflammatory and insulin sensitizer, offering a promising adjuvant therapy for T2DM management.
Pelatihan Bantuan Hidup Dasar (BHD) Bagi Jemaat Gereja HKBP Jl. Uskup Agung Sugiopranoto Medan: Upaya Peningkatan Pengetahuan dan Keterampilan Pertolongan Pertama pada Kondisi Gawat Darurat Dwi Lunarta Siahaan; Owen Sitompul; Marolop Hutapea; Joslouis Hutagaol; Horas Rajagukguk; Rebecca Rumesty Lamtiar; Jadeny Sinatra; Alexander P. Marpaung; Novrina Situmorang; Maesstro B. U. Simanjuntak; Harry Butar-butar; Ivonne R.V.O. Situmeang; Evirosa J. Simanjuntak; Inda M.H. Sinaga; Julenda I. Sebayang; Sanggam B. Hutagalung; Irene R. T. Damanik; Adrian Khu; Hanjaya Hanjaya; Nova Feronika Rajagukguk; Jekson M. Siahaan; Hadyanto Lim; Paul S. M. L. Tobing; Surjadi Rimbun; Ronald T.H. Tambunan; Juliyanti Tarigan; Kezia Stephanie S.; Karen Natalie S.
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 5 No 2 (2025): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol5No2.pp214-219

Abstract

Sudden death due to cardiac arrest and respiratory failure frequently occurs in the community, including in public places and houses of worship. Basic Life Support (BLS) is a simple yet crucial initial action to preserve life before advanced medical care is available. This community service activity was part of the HKBP Gotilon Festival 2025, organized in collaboration between the HKBP Church Jl. Uskup Agung Sugiopranoto Medan, Medical Faculty of Universitas Methodist Indonesia, Medical Faculty of Universitas HKBP Nommensen, and supported by the Indonesian Cardiovascular Specialist Association (PERKI) as experts. The program aimed to improve the knowledge and skills of the congregation of the HKBP Church in performing BLS. The methods included health education on the basic concepts of BLS, demonstration of cardiopulmonary resuscitation (CPR), and hands-on practice using mannequins. The results showed an increase in participants understanding of emergency response steps as well as their ability to perform CPR correctly. This activity is expected to raise community awareness of the importance of BLS skills and to equip them with the capability to provide initial assistance in emergency situations.
Hubungan Kadar Kolesterol Total Dengan Kolesterol LDL Pada Pasien Hipertensi Octavia So Hanggrainy; Hadyanto Lim; Surjit Singh
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.1392

Abstract

The Background: Cholesterol is an essential structural component that forms the cell membrane and the external layer of plasma lipoproteins. The increase of total cholesterol is always accompanied by the increase in LDL cholesterol especially in hypertensive patients. The present study was conducted to find the correlation between total cholesterol and LDL cholesterol of the patients with hypertension Method: It is an observational analytic using cross sectional study in which the data were collected by clinical laboratory examination of Prodia Jl. S.Parman no. 17/223G Medan, North Sumatra Indonesia. The population included all patients with hypertension in which the samples were taken by consecutive sampling method so the total were 19 samples. Results: Majority of samples had normal total cholesterol of 8 persons (42.1%) and the majority of the study samples had high LDL cholesterol of 8 persons (42.1%). Conclusion: There is a significant correlation between total cholesterol and LDL cholesterol. It is indicated by the sig-p value = 0.004 (p <0.05). There is a significant correlation between total cholesterol and LDL cholesterol of the patients with hypertension. It is indicated by the correlation coefficient value r-count = 0.635 which is between 0.6 - 0.79
Hubungan Hipertensi Dengan Mikroalbumin Urin Pada Usia Diatas 40 Tahun Rudy Cristianto Sagala; Hadyanto Lim; Surjit Singh
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.1410

Abstract

Background : Hypertension is the risk factor for cardiovascular disease and it is related with endothelial dysfunction. The disease is marked by microalbuminuria. Microalbuminuria is related with the damage of endothelial glomerulus and predictor of chronic renal failure. Microalbuminuria increases albuminuria. This will manifest as endothelial damage of the glomerulus. This study is to assess the relation between hypertension and microalbuminuria in people over 40 years of age Methods : in 13 subjects of essential hypertension in Medan, basic data down and their blood pressure and microalbumin checked in Clinical Laboratory of Prodia on Jl. S. Parman No. 17/223 G Medan. This research use cross section study. Shapiro-Wilk test conducted to find out normal distribution data and Pearson correlation test conducted to find out the relation between the variables. The significant score is P<0.05. Results : 6 subjects in this research were in category of A2 (moderate): 3-30 mg/mmol creatinine.7 subject in this study were in category A3(Severe): >30 mg/mmol creatinine. There was correlation (r = 0.898, p = 0.000) between systolic hypertension and microalbuminuria and the correlation between diastolic and microalbuminuria was (r = 0.574, p = 0.040). Conclusion: Hypertension is related with the increase of microalbuminuria for both systolic hypertension and diastolic Hypertension.
A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation : A Case of Complete Recovery From Recurrent Bell’s Palsy After Peripheral Blood Stem Cell Transplantation hadyanto lim; Eka Samuel P Hutasoit; Endy Juli Anto
Jurnal Kedokteran Methodist Vol. 17 No. 1 (2024): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v17i1.2812

Abstract

Background Recurrent Bell’s palsy is a rare condition that can affect the ipsilateral or contralateral to the affected side of the primary attack. There is still no consensus on treatment guidelines for recurrent Bell’s palsy. Therefore, we report a case of idiopathic recurrent contralateral facial palsy treated with autologous peripheral blood stem cell (PBSC) transplantation. Case Presentation A 72-year-old man presented with the sudden onset of right facial weakness, which was contralateral to the affected side of the first episode of facial palsy. The weakness had progressed with difficulty in closing the right eye, drooling the water from the right side of the mouth, and chewing impairment which was consistent with House Brackmann grade IV or moderately severe facial nerve grading system. He had exposure to cold stimulation, and a history of hypertension. He was given G-CSF 10 ug/kg/day for 5 days to mobilize stem cells, followed by apheresis on the 5th day. He did not receive acupuncture treatment. He had a complete recovery in 3 weeks with House Brackmann grade I or normal function of facial nerve. Conclusion Peripheral blood stem cell transplantation had a beneficial effect on the complete recovery of this recurrent Bell’s palsy and provides a treatment strategy in patients with unilateral facial palsy.
. Pengaruh Teh Hijau Pada Epigenetik dan Antiaging: The Effect of Green Tea on Epigenetics and AntiAging Imelda Imelda; Hadyanto Lim
Jurnal Kedokteran Methodist Vol. 18 No. 1 (2025): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jkm.v20i1.4467

Abstract

Background: The global increase in aging population poses major public health challenges. Green tea, especially its bioactive compound epigallocatechin gallate (EGCG), has shown promising effects on healthspan and age-related diseases. Recent studies have explored its potential role in epigenetic regulation and antiaging mechanisms. Discussion: Green tea is rich in polyphenols, especially catechins like EGCG, which act as powerful antioxidants. EGCG modulates epigenetic mechanisms by inhibiting histone deacetylases (HDAC), altering DNA methylation, and regulating non-coding RNAs. These modifications support the expression of genes involved in cellular protection, stress resistance, and longevity. In addition to systemic benefits, green tea also demonstrates topical antiaging effects by reducing oxidative stress and improving collagen synthesis in the skin. Experimental models reveal EGCG’s capacity to delay aging through activation of key signaling pathways (e.g., AMPK, SIRT1, FOXO) and modulation of inflammatory and apoptotic mediators. Clinical studies further confirm that consistent green tea intake is associated with reduced epigenetic age and improved biological markers of aging Conclusion: Green tea, through its epigenetic influence and antioxidant properties, presents itself as a natural and effective antiaging agent. Regular consumption may contribute to the prevention of age- related diseases and the promotion of healthy aging.
Co-Authors Adrian Khu Alexander P. Marpaung Alexander P. Marpaung AlexanderP.Marpaung Ardinata, Dedi - Blondina Marpaung br. Sembiring, Rehulina Br. T. Tambun, Gita Sradha Brar, Dylan Amrirtraj Chalil, M. Jalaluddin A. Diani Nazma Dina Riani Purba Dohude, Priscilla Putri Derlian Donny Nauphar Dwi Lunarta Docterina Sutanti Siahaan Dwi Lunarta Doderina Siahaan Eka Samuel P Hutasoit Eka Samuel P. Hutasoit Endy Juli Anto Evirosa J. Simanjuntak Evirosa J. Simanjuntak Fadinie, Wulan Fransella, Kezia Gultom, Helmida Hakim, Enggrek Pelita Hamdi, Tasrif Hanjaya Hanjaya Hanjaya, Hanjaya Harry Butar-butar Harry Butar-butar Hasni, Dita Hendrika A. Silitonga Henny Erina Saurmauli Ompusunggu Herlen, Aldo Horas Rajagukguk Horas Rajagukguk Hutagalung, Sanggam B. Hutasoit, Eka Samuel P Hutasoit, Eka Samuel P. Ilyas, Syaffrudin Imelda Imelda Inda M. H. Sinaga Inda M.H. Sinaga IndaM.Sinaga Irene R. T. Damanik Irene R. T. Damanik Irfan Hamdani, Irfan Irina, Sinta Ivonne R.V.O. Situmeang Ivonne R.V.O. Situmeang Jadeny Sinatra Jadeny Sinatra Jaminsen Sinaga Jan Pieter Sihombing Jeffrey ., Jeffrey Jesslyn Tan Joslouis Hutagaol Joslouis Hutagaol Julenda I. Sebayang Julenda I. Sebayang Julenda Sebayang Juli Jamnasi Juli Jamnasi Juli Y. Mega Juliyanti Tarigan Juliyanti Tarigan Juwita -, Juwita Karen Natalie S. Karen Natalie S. Kezia Stephanie S. Kezia Stephanie S. Koswara, Caroline Lamtiar, Rebecca Rumesty Laura Octavina Siagian Lesmana Syahrir Lubis, Andriamuri P. Lumban Raja, Alex Maruli Tua Maesstro B. U. Simanjuntak Maesstro B. U. Simanjuntak Maestro B. U. Simanjuntak Manullang, Frengky S. Marolop Hutapea Marolop Hutapea Mega, Juli Yosa Meilinda, Selvia Menang Bastanta Tarigan Natalie S., Karen Nova Feronika Rajagukguk Nova Feronika Rajagukguk Novrina Situmorang Nurwijayanti Octavia So Hanggrainy Ompusunggu, Henny E.S. Owen Sitompul Owen Sitompul Pakpahan, Edwin Anto Panggabean, Kristina Dameria Pardede, Sumondang M. Pasaribu, Sumihar Paul S. M. L. Tobing Paul Saut Marganda L Tobing Putri C. Eyanoer Rimbun, Surjadi Ronald T. H. Tambunan Ronald T. H. Tambunan Ronald T.H. Tambunan Rudy Cristianto Sagala Salomo G. U. Simanjuntak Sanggam B. Hutagalung Sanggam B. Hutagalung Sembiring, Budi Darmanta Siahaan, Jekson Martiar Sihite, Fiorella Natalia Kinanti Silaen, Ester L. R. Silitonga, Hendrika Adriana Simanjuntak, Salomo Garda Utama Simbolon, Boyke M. Sinatra, Jadeny Sinurat, Suryati Siregar, Kamal B. Sitepu, John Frans Stephanie S., Kezia Surjadi Rimbun Surjadi Rimbun Surjani, Lylys Surjit Singh Suryati Sinurat Tambunan, Ronald T. H. Tambunan, Ronald Tunggul Hotmarojahan Tanjung, Qodri F. Tarigan, Juliyanti Tarigan, Menang B Tarigan, Menang Bastanta Tengku M. Fauzi Tiji, Widjaya Taufik Tobing, Paul S. M. L. Umar Zein Vivian Vivian Yahwardiah Siregar Yohanna Agustina Sinaga YUNAFRI, ANDRI Zainumi, Cut M.