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All Journal JURNAL SISTEM INFORMASI BISNIS MediaTor: Jurnal Komunikasi Jurnal Simetris Mediator Bulletin of Electrical Engineering and Informatics Explore: Jurnal Sistem Informasi dan Telematika (Telekomunikasi, Multimedia dan Informatika) Pembangunan Pedesaan Journal of Information Systems Engineering and Business Intelligence Khazanah Informatika: Jurnal Ilmu Komputer dan Informatika Register: Jurnal Ilmiah Teknologi Sistem Informasi KLIK (Kumpulan jurnaL Ilmu Komputer) (e-Journal) Science and Technology Indonesia JOIV : International Journal on Informatics Visualization Jurnal Komputasi JOURNAL OF APPLIED INFORMATICS AND COMPUTING ComTech: Computer, Mathematics and Engineering Applications Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Buguh: Jurnal Pengabdian Kepada Masyarakat Jurnal Pepadun SWARNA: Jurnal Pengabdian Kepada Masyarakat JuTISI (Jurnal Teknik Informatika dan Sistem Informasi) Integra: Journal of Integrated Mathematics and Computer Science
Akmal Junaidi
Jurusan Ilmu Komputer Universitas Lampung
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Journal : JOIV : International Journal on Informatics Visualization

 1 
A New Feature Extraction Approach in Classification for Improving the Accuracy of Proteins Damayanti, -; Lumbanraja, Favorisen Rosyking; Junaidi, Akmal; Sutyarso, -; Susanto, Gregorius Nugroho; Megawaty, Dyah Ayu
JOIV : International Journal on Informatics Visualization Vol 9, No 1 (2025)
Publisher : Society of Visual Informatics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62527/joiv.9.1.2589

Abstract

Proteins play a vital role in life as essential macromolecules, consisting of linear heteromeric biopolymers formed by amino acids covalently bonded through peptide bonds. They contribute to cell development and bolster the body's defense mechanisms. Post-translational modification processes, such as glycosylation, are necessary for proteins to function optimally. Glycosylation involves adding sugar groups to proteins, playing a critical role in various protein folding processes. Dysregulation of protein glycosylation can lead to diseases like Alzheimer's and cancer. Manual classification of glycosylated proteins is time-consuming, necessitating a faster approach. This study aims to expedite glycosylated protein classification using novel methods like AAindex, CTD, SABLE, hydrophobicity, and PseAAC for increased accuracy, comparing them with existing approaches. The dataset comprises protein sequences sourced from the openly accessible UniProt database. Results demonstrate that glycosylated protein prediction achieved 100% accuracy, surpassing previous approaches. Several features contributed to this improvement, with Hydrophobicity making a significant contribution at 24%, and PseAAC making the most significant contribution at 40% among the five extraction methods developed.
Co-Authors - Damayanti . Wamiliana Admi Syarif Ahmad Ari Aldino Ahmad Faisol Akbar, Mohammed Raihan Albertus Sudirman Alfikri, Fadli Andrian, Rico Ani Kurniawati Arif Munandar Arif Pebriansyah Asmiati Asmiati Astria Hijriani Astria Hijriani Astria Hijriani, Astria Ayu Amalia Ayu Nadila Bambang Hermanto Damayanti Damayanti Dwi Sakethi Dwi Sakethi Dwi Sakethi Fajriyanto Fajriyanto Favorisen R. Lumbanraja Fazri, Yudistira Febi Eka Febriansyah Fitriani Gamal, Mohammad Danil Hendry Hamim Sudarsono . Heningtyas, Yunda Herindri Samodera Utami, Bernadhita Hidayat Pujisiswanto Ida Nurhaida1 Ida Nurhaida Ida Nurhaida Indah Mayatika Sihaloho Innaya, Thalia Gemi Irawati, Anie Rose Irwan Adi Pribadi Irwan Adi Pribadi Iva Mutiara Indah Kartika Sari Kenny Claudie Fandau Kurnia Muludi Leila Fauziah Lucia Ratnasari Lumbanraja, Favorisen Rossyking Machudor Yusman Machudor Yusman Maharani, Devi Manurung, Yunita Rosalina Megawaty, Dyah Ayu Meizano Ardhi Muhammad Muhammad Iqbal Muhammad Jamaludin Muhammad, Meizano Ardhi Mustofa Usman Naurah Nazhifah Nikken Prima Puspita Nirwana Hendrastuty Nova Ayu Lestari Siahaan Novita Dwilestari Nugroho Susanto, Gregorius Nurdin, Muhaymi Ossy Dwi Endah Wulansari Ossy Dwi Endah Wulansari, Ossy Dwi Endah Pairul Syah Pairulsyah Pairulsyah Prabowo, Rizky Pranata, Beni Adi Rahmat Safe'i Rahmi Permata Hati Rangga Agustiantino Rangga Firdaus Rendi Adam Rendi Eko Prasatiawan Reni Permata Sari Reza Aji Saputra Rizky Ramadhany Rosdiana, Siti Rosyking Lumbanraja, Favorisen Rusdi Evizal S Susiyani SAIFUL ANWAR Saipul Anwar Saipul Anwar Samsul Bakri Shofiana, Dewi Asiah Sholehurrohman, Ridho Siti Khabibah Siti Rosdiana Slamet Budi Yuwono Sugaluh Yulianti Sugeng P Hariyanto Sugeng P Hariyanto Sugeng Prayitno Hariyanto Susanto, Gregorius Nugroho Sutyarso Sutyarso Sutyarso, - Syachrul Priyo Wibowo Syifa Trianingsih Taqwan Thamrin Tio Arisandi Titik Nur Aeny Trianingsih, Syifa Tsani, Machya Kartika Wamiliana Warsono Warsono Wartariyus Wartariyus Wiwin Susanty Wulan Kurnia Safitri Yoannisa Egeustin YOHANA TRI UTAMI, YOHANA TRI Yusikania Dwi Putri Zaenal Abidin Zaini, TM