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All Journal Pharmaciana: Jurnal Kefarmasian PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmiah Farmasi Farmasyifa Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Riset Farmasi Pharmaceutical Sciences and Research (PSR) Bandung Conference Series: Pharmacy Jurnal Pengabdian Masyarakat (Jupemas)
Yani Lukmayani
Universitas Islam Bandung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Penetapan Kadar Flavonoid Total dan Pengujian Aktivitas Antioksidan Ekstrak Etanol 96% Biji Pepaya (Carica Papaya L.) Varietas Bangkok Pradini Shulistiya; Yani Lukmayani; Vinda Maharani Patricia
Jurnal Riset Farmasi Volume 5, No. 1, Juli 2025, Jurnal Riset Farmasi (JRF)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrf.v5i1.6813

Abstract

Abstract. Bangkok papaya (Carica papaya L.) seeds contain flavonoid compounds that are thought to have antioxidant activity. This study aims to determine the total flavonoid content and determine the antioxidant activity of 96% ethanol extract of Bangkok papaya seeds. The extraction of Bangkok papaya seeds was done using the maceration method. Determination of total flavonoid content was done by colorimetric method using AlCl3 reagent with quercetin comparator and antioxidant activity testing was done by DPPH (2,2-diphenyl-1-picrylhydrazyl) method using vitamin C comparator. The results showed that the total flavonoid content was 192,80 mgQE/gr extract and the IC50 value of 96% ethanol extract of papaya seeds (Carica papaya L.) Bangkok variety was 2.374,79 ppm which is included in the category of very weak antioxidant activity. Abstrak. Biji pepaya (Carica papaya L.) varietas Bangkok mengandung senyawa flavonoid yang diduga memiliki aktivitas antioksidan. Penelitian ini bertujuan untuk menentukan kadar flavonoid total dan mengetahui aktivitas antioksidan dari ekstrak etanol 96% biji pepaya varietas Bangkok. Ekstraksi biji pepaya varietas Bangkok dilakukan dengan metode maserasi. Penetapan kadar flavonoid total dilakukan dengan metode kolorimetri menggunakan pereaksi AlCl3 dengan pembanding kuersetin dan pengujian aktivitas antioksidan dilakukan dengan metode DPPH (2,2-diphenyl-1-picrylhidrazil) menggunakan pembanding vitamin C. Dari hasil penelitian didapatkan kadar flavonoid total sebesar 192,80 mgQE/gr ekstrak dan nilai IC50 ekstrak etanol 96% biji pepaya (Carica papaya L.) varietas Bangkok sebesar 2.374,79 ppm yang termasuk dalam kategori aktivitas antioksidan sangat lemah.
Co-Authors . Supriyatna Abdul Muis Abdul Muis Abdurrasyid Fadhlurrahim Agung Gunawan Ainun Navisah Ambariyanto Ambariyanto Amila Gadri Anggi Arumsari Arinda Roosma Devi Zulfitriyana, Devi Zulfitriyana Devinur Rahmawati EGA MULYA PERMATA DEWI Esti Rachmawati Sadiyah Fatia Asy-Syahidah Al-Haq Fazreen Dwi Putri Anggia Fazreen Fetri Lestari Fetri Lestari Giffar Abdiljabbar Najmudin Gina Kurniawati Glorida P. S. Hanny Hafiar Hilda Aprilia, Hilda Indra Topik Maulana Khansa Fitrah Shaliha Kiki Mulkiya Kiki Mulkiya Yuliawati Lanny Mulqie Livia Syafnir Livia Syafnir Mahda Nur Nahjatun Naajiyah Nadia Rahayu Nadia Nisa Rahma Aniyati Novia Nur Islamiati P. S, Glorida Pradini Shulistiya Putri Kurnia Sari Ratih Aryani Ratih Aryani, Ratih Reza Abdul Kodir Rusnadi Rusnadi Sadiyah, Esti Rachmawati Sherly Aeldha Anuzar Siti Romlah Sri Puan Hanum Thyazen Abdo Hizam Alhakimi Tsaniya Fatima Khanza Umi Yuniarni Umi Yuniarni Vinda Maharani Patricia Wildan Khaidir Amarulloh Wini Dwiyunianti Yuliani Ika Pratiwi