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The Prediction of Curcumin Content in the Turmeric Rhizome with Raman Handheld Spectroscopy I Made Agus Gelgel Wirasuta; Cokorda Istri Tirta Rusmala Dewi; Ni Putu Linda Laksmiani; I Gusti Ayu Made Srinadi; Deddi Prima Putra
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.832 KB) | DOI: 10.24198/ijpst.v5i3.16315

Abstract

The quality control of herbal medicine should be started from the determination of the active substance at harvest time. The Raman spectrometry has been used for this propose. The aim of this study is to determine the quantification of curcumin in turmeric rhizome (Curcuma longa Linn.) using Raman spectroscopy combined with multivariate analysis of PLS-R that are expected to provide reference method for quality control in turmeric rhizome, especially for raw materials of Herbal drugs. Parameters that can be used for analysis of curcumin levels on turmeric rhizome obtained using intensity of data Raman and the data obtained from the standard method will be processed with multivariate analysis methods PLS-R. The validation value of quantification result using Raman-PLSR is seen from R2 value of 0.957, RMSEC value of 0,199 and p-value of 0.00. The study showed the developed method could be implemented on to determine the prediction quantification of raw material herbal medicine.Keyword : Curcumin,  PLS-R, Turmeric, Raman Spectroscopy
Pengaruh Pelayanan Kefarmasian Residensial terhadap Ketaatan dan Luaran Klinis Pasien Hipertensi Luh P. F Larasanty; Ni Made L. Meilinayanti; Ni Made P. Susanti; I Made A.G. Wirasuta
Indonesian Journal of Clinical Pharmacy Vol 4, No 3 (2015)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (47.214 KB) | DOI: 10.15416/ijcp.2015.4.3.162

Abstract

Pada era jaminan kesehatan nasional, salah satu target pelayanan kefarmasian residensial adalah pasien hipertensi yang masuk ke dalam kategori kelompok pasien rujuk balik. Penelitian ini bertujuan untuk mengetahui pengaruh pelayanan kefarmasian residensial yang dilakukan apoteker terhadap ketaatan dan luaran klinis pasien hipertensi tanpa penyakit penyerta yang menjalani rawat jalan di Rumah Sakit Umum Daerah Wangaya Kotamadya Denpasar Bali. Desain penelitian ini adalah eksperimental dengan one group pre-post test design. Sebanyak 13 pasien yang memenuhi kriteria inklusi diberikan pelayanan kefarmasian residensial selama 16 kali kunjungan dalam kurun waktu tiga bulan. Skor hasil pengukuran dianalisis menggunakan regresi linier dan Uji Wilcoxon. Pelayanan kefarmasian residensial mampumeningkatkan ketaatan pasien dalam penggunaan obat, pengaturan diet, dan aktivitas fisik dari tingkat baik menjadi tingkat ketaatan tinggi (p=0,001) serta dapat meningkatkan ketaatan pasien terhadap pembatasan konsumsi alkohol dan rokok dari tingkat baik menjadi sangat baik. Pelaksanaan pelayanan kefarmasian dapat memberikan pengaruh dalam perbaikan luaran klinis pasien berupa penurunan tekanan darah sistolik (p=0,000). Pelayanan kefarmasian residensial memiliki pengaruh terhadap peningkatan ketaatan pasien terhadap penggunaan obat, pelaksanaan diet, pelaksanaan aktivitas fisik, serta terhadap pembatasan rokok dan konsumsi alkohol sehingga dapat memperbaiki luaran klinis pasien hipertensi.Kata kunci: Hipertensi, ketaatan pasien, pelayanan kefarmasian residensial, tekanan darahImpact of Pharmaceutical Home Care on Compliances and Clinical Outcomes of Hypertensive PatientsIn the Indonesian health universal coverage system the hypertensive patients that grouped into the refer back patient treatment category, is one target of pharmaceutical home care. The aim of this study was to carried out the impact of pharmaceutical home care on patient compliances and clinical outcomes ofhypertension without compeling indication out-patient on Wangaya General Hospital in the municipality of Denpasar Bali. Design research is an experimental study with one group pre-post test design. The thirteen patients who met the inclusion criteria will be given pharmaceutical home care services for 16 visits over three months period. The complianced levels were scored and statistical analyzed using linear regression and wilcoxon test. The pharmaceutical home care visit could increase the patients adherence to antihypertensive drug administration, increasing diet compliance, and adherence of physical exercise from good adherence to excellent adherence (p value=0,001), Pharmaceutical home care visit could increase patient compliance to restrictions of smoking and alcohol consumption from good adherence to very good adherence. The decreasing of the patient’s systolic blood pressure correlated to the pharmacist home visit (p value=0,000). The pharmaceutical home care has influenced on health behavior of hypertensive patients and the patients concordance to take their medication and introduced better clinical outcome.Keywords: Blood pressure, hypertension, patient compliances, pharmaceutical home care
UJI PENAPISAN DAN PENETAPAN KADAR MORFIN DAN KODEIN DALAM PLASMA MENGGUNAKAN HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY- SPEKTROFOTODENSITOMETRI I Made Agus Gelgel Wirasuta; Dewa Ayu Swastini; Ni Made Pitri Susanti
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 7 No 2 (2019): volume 7, Nomor 2, 2019
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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Abstract

ABSTRAK: Uji skrining dan konfirmasi kandungan morfin dan kodein dalam plasma telah dikembangkan menggunakan high-performance thin-layer chromatography (HPTLC)-Spektrofotodensitometri. Penetapan kadar morfin dan kodein pada plat HPTLC dideteksi pada panjang gelombang 212 nm. Ekstraksi morfin dan kodein dari plasma menggunakan campuran kloroform dan isopropanol, dengan menggunkan metanol atau isopropanol sebagai pengendap protein. Uji konfirmasi dengan teknik di atas belum memberikan hasil yang kurang tajam. Batas dekteksi morfin adalah 48,8 ng dan kodein 70,2 ng. Diperoleh variasi batas deteksi dan batas kuantisasi analit yang sangat besar antar plat HPTLC walaupun memberikan persamaan regrasi yang hampir sama. Kata Kunci: Uji skrining, Konfirmasi, morfin, kodein, HPTLC ABSTRACT: Screening and confirmation test for morphine and codeine by high-performance thin-layer chromatography-densitometry technique has been carried out. The determination test consist of limit detection (LOD) and limit quantification (LOQ) of the analyte using HPTLC scanned on wave length of 212 nm. The morphine and codeine were extracted by liquid-liquid extraction using mixture of chloroform and isopropanol from plasma. The screening and confirmation test based on corrected hRf – value and insitu UV-spectrum of analyte delivered a not convenient result. The LOD of morphine and codeine was 48,8 and 70,2 ng. The determination of opiate by HPTLC-densitometry was obtained a great range of LOD and LOQ between plat of HPTLC, although had a fast equal of linear regression-coefficient.
IDENTIFIKASI EFEDRIN HIDROKLORIDA, DEKSTROMETORFAN DAN TRAMADOL HIDROKLORIDA DALAM TABLET DENGAN SPEKTROSKOPI RAMAN Khairul Mahfuz; I Made Agus Gelgel Wirasuta; Ni Made Suaniti
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 5 No 2 (2017)
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

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Abstract

ABSTRAK: Penelitian ini bertujuan untuk mengetahui perubahan pola spektrum Raman Efedrin Hidroklorida, Dekstrometorfan dan Tramadol Hidroklorida pada tablet obat (Decolsin®,Tramifen®) dan sampel simulasi. Tablet Obat serta sampel simulasi Efedrin Hidroklorida, Dekstrometorfan dan Tramdol Hidroklorida dengan konsentrasi 80%, 60%, 40% dan 20% dalam serbuk Amprotab diukur dengan spektroskopi Raman 1064 nm pada bilangan gelombang 200-2000 cm-1. Hasil yang didapat dianalisis dengan cross correlation function dan dilihat nilai koefisien korelasi (r). Pada masing-masing tablet Obat hanya Parasetamol yang dapat diidentifikasi karena nilai koefisien korelasi r > 0,95. Berdasarkan hasil sampel simulasi diketahui bahwa konsentrasi Efedrin Hidroklorida, Dekstrometorfan dan Tramadol Hidroklorida pada suatu campuran berpengaruh terhadap pola spektrum Raman yang dihasilkan. Pola puncak spektrum Raman untuk identifikasi Efedrin Hidroklorida yaitu pada bilangan gelombang 1305 cm-1 (C-N), 1380 cm-1 (C-CH3), 1662 cm-1 (C=C), 1600 cm-1 (C-OH), dan 315 cm-1 (C-C alifatik); Dekstrometorfan yaitu puncak pada bilangan gelombang 1040 cm-1 (cincin Aromatis I), 1495 cm-1 (cincin Aromatis II), 768 cm-1 (C-Cl), 1580 cm-1 (cincin Hetero), 1667 cm-1 (C=C ) dan 855 cm-1 (C-O-C); Tramadol Hidroklorida yaitu puncak pada bilangan gelombang 1006 cm-1 (cincin aromatis I), 1467 cm-1 (cincin aromatis II), 1552 cm-1 (C-OH), 1635 cm-1 (C=C), 285 cm-1 (C-C Alifatik), 1345 cm-1 (C-N) dan 855 cm-1 (C-O-C). ABSTRACT: The aims of this study were determined to change in the pattern of Raman spectrum of Ephedrine Hydrocloride, Dextrometorfan and Tramadol Hydrocloride on tablet (Decolsin®,Tramifen®) and simulation samples. Tablets and simulation samples of this active compound made in Amprotab with concentration 80%, 60%, 40% and 20% measured by 1064 nm Raman spectroscopy in wave numbers 200-2000 cm-1. The results can be analyzed by cross-correlation function and showed the value of the correlation coefficient r. On tablet only Paracetamol can be identified because it has coefficient correlation r > 0,95. Based on the results of the simulation sample is known that the concentration of active compound in a mixture affect the pattern of the Raman spectra. Peak pattern to identification Ephedrine Hydrocloride is at wave number 1305 cm-1 (C-N), 1380 cm-1 (C-CH3), 1662 cm-1 (C=C), 1600 cm-1 (C-OH), dan 315 cm-1 (C-C alifatik); Dextrometorfan is at wave number 1040 cm-1 (Aromatic Ring I), 1495 cm-1 (Aromatic Ring II), 768 cm-1 (C-Cl), 1580 cm-1 (Hetero Ring), 1667 cm-1 (C=C ) dan 855 cm-1 (C-O-C); Tramadol Hydrocloride is at wave number 1006 cm-1 (Aromatic Ring I), 1467 cm-1 (Aromatic Ring II), 1552 cm-1 (C-OH), 1635 cm-1 (C=C), 285 cm-1 (C-C Alifatik), 1345 cm-1 (C-N) and 855 cm-1 (C-O-C).
LAJU HIDROLISIS HEROIN DALAM AIR DAN PLASMA I M. A. G. Wirasuta; M. A. Ningtyas; E. I. Setyawan
Jurnal Kimia (Journal of Chemistry) Vol.13 No.2 Juli 2019
Publisher : Program Studi Kimia, FMIPA, Universitas Udayana (Program of Study in Chemistry, Faculty of Mathematics and Natural Sciences, Udayana University), Bali, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.05 KB) | DOI: 10.24843/JCHEM.2019.v13.i02.p11

Abstract

Heroine is hydrolyzed spontaneously in water and plasma. This will influence the determination, especially on the drug profiling. Spectrophotodensitometry has been used to analyze drug profiling of illicit heroine. This article reports the AL-TLC separation of heroine, 6-monoacetylmorphine (6-MAM), morphine, acetyl codeine, and the heroine hydrolysis in water and plasma. Heroin, 6-MAM, morphine, and acetyl codeine can be well-separated by mobile phase of toluene:siclohexane:diethyl amine (75:15:10, v/v). The limit of detection was 165.16 ng/spot and the limit of quantification was 550.55 ng/spot. Heroine was hydrolyzed in water and plasma under first order reaction. The rate of reaction was 0.55 min-1 in water with the half time reaction of 12.47 minutes. On the other hand the hydrolysis rate in plasma was slower with the half time of 16 minutes. Keywords : hydrolysis, heroin, water, TLC-spectrophotodensitometer
PEMBINAAN PETANI DI DESA SONGAN, KECAMATAN KINTAMANI-BANGLI MENGENAI PENGGUNAAN PESTISIDA N. M. Utami Dwipayanti; M. Ayu Hitapretiwi Suryadhi; N K. Sutiari; I N. Sujaya; I Agus Gelgel Wirasuta; N T. Suryadhi
Buletin Udayana Mengabdi Vol 11 No 1 (2012): Volume 11 No.1 – April 2012
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

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Abstract

The knowledge of farmers on pesticides and its association on health and the environment still remains an issue. Located in the rural area of Bali, the village of Songan, Kintamani, Bangli with its fertile soil accommodates many farm lands. The counseling and assistance included 20 farmers during their working hours to allow direct observation. The counseling and assistance targeted at issues regarding safe uses of pesticides and its association to health and the environment. The knowledge of participants was evaluated by pre- and post-test. Less than a half (40%) were able to identify an association between pesticide use and health, while almost all do not know the chronic effect of pesticides to health and/or the environment. Recommendations target health care facilitators are expected to continue counseling and assistance to the farmers and others in order to maintain a healthier and more sustainable future.
PEMBINAAN PETANI DI DESA SONGAN, KECAMATAN KINTAMANI-BANGLI MENGENAI PENGGUNAAN PESTISIDA N . M. Utami Dwipayanti; M. Ayu Hita Pretiwi Suryadhi,; N. K. Sutiari; I. N. Sujaya; I M. Agus Gelgel Wirasuta; N. T. Suryadhi
Buletin Udayana Mengabdi Vol 13 No 2 (2014): Vol 13, No. 2 (2014)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (540.681 KB)

Abstract

The knowledge of farmers on pesticides and its association on health and the environment still remains an issue. Located in the rural area of Bali, the village of Songan, Kintamani, Bangli with its fertile soil accommodates many farm lands. The counseling and assistance included 20 farmers during their working hours to allow direct observation. The counseling and assistance targeted at issues regarding safe uses of pesticides and its association to health and the environment. The knowledge of participants was evaluated by pre- and post-test. Less than a half (40%) were able to identify an association between pesticide use and health, while almost all does not know the chronic effect of pesticides to health and/or the environment. Recommendations target health care facilitators to continue counseling and assistance to the farmers and others in order to maintain a healthier and sustainable future.Keyword: pesticide, health, environment, farmers knowledge
Tingkat Kesepahaman Masalah terkait Obat antara Dokter dan Apoteker di Apotek Fauna Herawati; Ni Nyoman Yuni Astrini; I Made Agus Gelgel Wirasuta
MPI (Media Pharmaceutica Indonesiana) Vol. 1 No. 2 (2016): DECEMBER
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.534 KB) | DOI: 10.24123/mpi.v1i2.190

Abstract

Kolaborasi antar tenaga kesehatan diperlukan untuk meningkatkan pelayanan kesehatankepada pasien. Kolaborasi antar tenaga kesehatan didefinisikan sebagai profesional tenaga kesehatandengan peran yang saling melengkapi dan kooperatif bekerja sama, berbagi tanggung jawab untukpemecahan masalah dan pengambilan keputusan untuk merumuskan dan melaksanakan rencanaperawatan pasien; demikian pula dalam kolaborasi dokter dan apoteker, diperlukan kesepahamantentang masalah terkait obat. Penelitian ini bertujuan untuk mengukur tingkat kesepahaman dokter-apoteker di klinik pada periode September-Oktober 2013. Penelitian ini menggunakan metodedeskriptif observasional dan dilakukan di salah satu apotek di Bali yang bekerja sama dengan dokterspesialis penyakit dalam. Sampel penelitian adalah resep dokter spesialis penyakit dalam untukpasien diabetes mellitus (DM) dan pengambilan resep dilakukan secara consecutive sampling. Jumlahsampel yang berhasil diperoleh berjumlah 102 lembar resep pasien diabetes melitus rawat jalanyang akan dianalisis melalui 3 tahap dengan menggunakan elemen medication therapy management(MTM), daftar periksa the Pharmaceutical Care Network Europe (PCNE) versi 6.2, dan kappa agreement.Hasil analisis menunjukkan tingkat kesepahaman (κ) sebesar 0,84. Kesepahaman antara dokterdan apoteker tentang masalah terkait obat sangat baik (95% sepaham); ketidaksepahaman terutamaterkait pertimbangan klinis penggunaan obat dan kepatuhan pasien, oleh karena itu apotekerperlu meningkatkan pengetahuan agar dapat berkontribusi dalam kolaborasi tersebut. Apotekerdalam kolaborasi interprofesional dapat berperan dalam pengaturan dosis, identifikasi efek samping,rekonsiliasi pengobatan, dan memberikan rekomendasi terapi berbasis bukti.
Kesesuaian Informasi Kontraindikasi Obat Gastrointestinal Untuk Pasien Geriatri Pada Berbagai Sumber Informasi Tersier I Made Agus Gelgel Wirasuta; Anak Agung Febi Danuswari; Luh Putu Febriyana Larasanty
Acta Pharmaceutica Indonesia Vol. 39 No. 3 & 4 (2014)
Publisher : School of Pharmacy Institut Teknologi Bandung

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Abstract

Penggunaan obat gastrointestinal meningkat seiring penurunan fungsi sistem gastrointestinal pada populasi geriatri. Informasi kontraindikasi merupakan salah satu informasi keamanan yang diperlukan bagi pasien geriatri. Informatorium Obat Nasional Indonesia (IONI), Informasi Spesialite Obat (ISO), British National Formulary (BNF), dan Drug Information Handbook (DIH) merupakan sumber informasi tersier yang memuat informasi keamanan penggunaan obat. Penelitian ini bertujuan untuk mengetahui kesesuaian informasi kontraindikasi obat gastrointestinal untuk populasi geriatri pada sumber informasi tersier dengan Beers List sebagai pustaka acuan.Penelitian dilakukan dengan studi kepustakaan pada informasi kontraindikasi penggunaan obat gastrointestinal untuk pasien geriatri pada sumber literatur tersier. Sampel obat gastrointestinal diperoleh dari pendataan pada buku Farmakologi Dasar dan Klinik, diperoleh 20 jenis obat yang informasi keamanan tercantum pada keempat sumber informasi tersier yang digunakan. Informasi kontraindikasi 20 obat tersebut didata pada masing-masing sumber informasi tersier, kemudian dikonfirmasi silang dengan informasi pada Beers List, sehingga diperoleh persentase kesesuaian informasi kontraindikasi pada masing-masing sumber informasi tersier. Hasil penelitian menunjukkan bahwa 20 jenis obat gastrointestinal yang digunakan dalam penelitian tidak dikontraindikasikan untuk populasi geriatri. Informasi pada Beers List juga menyatakan bahwa penggunaan obat tersebut tidak dikontraindikasikan pada populasi geriatri, sehingga informasi kontraindikasi penggunaan obat gastrointestinal pada keempat sumber informasi tersier sesuai dengan informasi yang tercantum pada Beers List.Kata kunci: geriatri, informasi keamanan, obat gastrointestinal.AbstractUses of gastrointestinal drugs was increased as the decline in the function of the gastrointestinal system in the geriatric population. Contraindication information is one of the safety information that is required for geriatric patients. Informatorium Obat Nasional Indonesia (IONI), Informasi Spesialite Obat (ISO), the British National Formulary (BNF), and the Drug Information Handbook (DIH) is a tertiary drug information source that includes information of safety drug use. This study aims is to determine the suitability of the information gastrointestinal drug contraindications to the geriatric population in various tertiary resources with Beers List as its reference library.This research are literature study on the use of contraindicated information of gastrointestinal drugs for geriatric patients at tertiary literature sources. Gastrointestinal drug samples listed from Basic and Clinical Pharmacology book, obtained 20 types of generic drug that safety information contained in the all of tertiary resources are used in this study. Contraindications information of those drug in each tertiary resources, then cross confirmed with the information on Beers List, in order to obtain the percentage of suitability of contraindicated information in each tertiary resources.The results showed that 20 type of gastrointestinal drugs used in this study were not contraindicated in geriatric population. Information on the Beers List also states that the use of the drug is not contraindicated in the geriatric population. It is concluded that the contraindicated information of gastrointestinal drug use in geriatric population in IONI, ISO, DIH and BNF is in accordance with the information listed on the Beers List.Keywords: geriatric, gastrointestinal drug, safety information
ANTIOXIDANT ACTIVITY TEST OF ANDROGRAPHOLIDE IN BITTER HERBS USING DPPH SCAVENGING Ni Made Pitri Susanti; Ni Kadek Warditian; I Made Agus Gelgel Wirasuta
Journal of Health Sciences and Medicine Vol 1 No 1 (2017): JHSM (Febuary 2017)
Publisher : Institute for Research and Community Services Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.435 KB) | DOI: 10.24843/JHSM.2017.v01.i01.p03

Abstract

Abstract Bitter herbs (Sambiloto) have many pharmacological activities including antioxidant, antidiabetic, anticancer, antihyperlipidemic and anti-inflammation. Andrographolide is a diterpene compounds contained in bitter herbs. It is known that andrographolide compound responsible for the pharmacological activity of the bitter herbs. This study investigated DPPH free radical scavenging activity from andrographolide diterpene lactone. This study was initiated with the isolation of andrographolide compound from bitter herbs and then testing their DPPH free radical scavenging. The results suggested that andrographolide had IC50 value of 5.45 mg. This means andrographolide has 50% DPPH inhibition effect, i.e 5.45 mg.
Co-Authors A.A Wahyudhie A.A.Diah Widya Lestari A.A.G.R.Y. Putra Adiluhur M. A. Anak Agung Febi Danuswari Angga Cahyadi Arie Dharma Putra Nugraha Arimbawa I.B.S. Astiti, I.A.G. Astrini, Ni Nyoman Yuni Astuti N.M.W. Atika Saraswati Ni Made Ayu Charina Mahayuni TK. Bagus Nyoman Sugiastana Budiningrum, N.W. C.I.T.R. Dewi Cahyadi K.D. Cahyadi, Maria Fiani Cokorda Istri Sri Arisanti Cokorda Istri Tirta Rusmala Dewi Coky N. W. C. Danuswari, Anak Agung Febi Deddi Prima Putra Desta, I.G.A.G.P.C Deviyanthi, Kadek Sintia Dewa Ayu Sri Kusuma Dewi Dewa Ayu Swastini Dewantari A. A. I. S. H Dewi L. R. Dewi, A.A.R.P. Dewi, Cokorda Istri Tirta Rusmala Dewi, L. P. M. K. Dewi, N.P.A.K. Dharmapradnyawati N.N.P. Diantari, N.M.D Diarini A. S. Dyah Aryani Sartika Eka Indra Setyawan Emmy Sahara Fauna Herawati Fiorenza Jocelyn Thelmalina G.D. Pranawa Guna, I. M. A. W. H. Kijewski H.-J. Duchstein Harlina Setiawati Manurung I G.A.A. Trisnadewi I G.D.B. Temaja I G.L.B. Wirajaya I Gede Budiartawan I Gusti Ayu Made Srinadi I Gusti Ngurah Jemmy Anton Prasetia I Ketut Adnyana I Made Ari Anata I Made Arie Dharma Putra Nugraha I Made Jawi I Made Sasmita Dwidhananta I Made Sasmita Dwidhananta I N.K. Widjaja I Nengah Sujaya I Nengah Wirajana I Nyoman Arsana I Nyoman Kadjeng Widjaja I Putu Hengky Prawiranata I Putu Krisnantara Wijaya Putra I Putu Sudiartawan I Wayan Martadi Santika I. N. K. Widjaja I.A.A. Widhiartini I.M.S. Sapanca I.Y.J. Wage Icwari N.P.W.P Ida Bagus Putra Suta Ida Bagus Wiryanatha Indrani, A.A.I. S. Indriani N. P. W. Jaya M.K.A Jessica Lianty K. G. Gityarani K.D. Cahyadi Kadek Hendra Kadek Sintia Deviyanthi Ketut Widyani Astuti Khairul Mahfuz Khatija Taher Ali Kosasih, Diah Ayu Nirmala Kusuma Hidayatullah L. P. M. K. Dewi Laksmi Dewi Luh Putu Febryana Larasanty Luh Putu Mirah Kusuma Dewi Luh Rai Maduretno Asvinigita M. A. Ningtyas M. Primantara M.A. Wiradarma Made Ayu Hita Pretiwi Suryadhi Made Gede Praditya Putra Mahardika I G.A.P.D. Maria Fiani Cahyadi Meilinayanti, Ni Made L. Milawati Milawati Mirayanti, Ni Putu Dinda N T. Suryadhi N. G. Indriyaningsih N. L. P. V. Paramita N. T. Suryadhi N.K.A. Julianty N.L.P.P. Ardiyanti N.M.D. Diantari N.M.N.P. Dewi N.M.P. Dwijayanti N.M.P. Susanti N.M.P. Susanti N.M.W. Astuti N.P. Widiastuti N.P.C. Pratiwi N.P.R.D. Putri Nachia S.R. Ni Kadek Diah Parwati Dewi Ni Kadek Warditian Ni Kadek Warditiani Ni Ketut Sutiari Ni Komang Dewi Triastuti Ni Luh Gede Sudaryati Ni Luh Putu Lestari Dewi Ni Made Ari Ginarsih Ni Made Ary Sarasmita Ni Made Ayu Wistari Ni Made Irma Febby Prasasti Dewi Ni Made L. Meilinayanti Ni Made Listiari Ni Made P. Susanti Ni Made Pitri Susanti Ni Made Rai Sudarni Ni Made Suaniti Ni Made Utami Dwipayanti Ni Made Widi Astuti Ni Made Widiastuti Ni Nyoman Abigail Triastuti Ni Nyoman Della Yanti Ni Nyoman Putri Dharmapradnyawati Ni Nyoman Yuni Astrini Ni Putu Citra Anggryni Sugitha Ni Putu Eka Leliqia Ni Putu Linda Laksmiani Ni Wayan Wirayanti Nugraha, I.S. Oka M. P.P.K. Vedawati P.R. Satriari Pande Made Nova Armita Pande Made Nova Armita Sari Pande Made Nova Armita Sari, Pande Made Nova Pinangkaan, C. Pratiwi Diva Yanti Luh Prawiranata I.P.H. Primadewi C. Purnama, I.G.P.P Putra, I.M.K. Putri I G.A.A.R.C. Putu Dyah Utari Putu Lakustini Cahyaningrum Putu Nandya Nandita Putu Oka Samirana Rashid, M.A.P.P Rasmita, L.D. Rismayanti, A. A. M. I. Roedy Aris Tavip Sari, D. R. A. P. Sari, N. A. P. P. Sari, Ni Putu Latsartika Sari, P. M. N. A. Sartika, Dyah Aryani Shelia Deviana Suastika, I.G.A. Suastini I G.A.N. Sudarni, Ni Made Rai Sugosha, M. J. Sukamto, Ika Sumiyarsi Sukawati, C. B. A. C Sumawirawan, K. D. Suryani N.K.A. Suryani, N.M. Susanti N.M.P Susanti, I.M.P. Susanti, N.M.P Swasti, I.A.S. Triastuti, Ni Komang Dewi Trisna Damayanti Udayana, N.K Utami N.P.P. Utari, Putu Dyah Widhiastuti, K.A.P. Widjaja I.N.K. Widjaja, I. N. K. Winarti, N.W. Wintari L.K.S. Wiputri N.M.C.A. Wistari, Ni Made Ayu Wulansari, I. A. R. Yanti, N.L.G.T Yudiastra, I.K. Yustiantara, Putu Sanna Yustiantara, Putu Sanna