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POLA PERESEPAN OBAT ANTIDIABETIK PADA PASIEN DIABETES MELITUS TIPE 2 DI POLI PENYAKIT DALAM RS “X” SIDOARJO PERIODE OKTOBER- DESEMBER 2019 Yugo Susanto; Sri Bangun Lestari; Elly Purwati
AFAMEDIS Vol. 1 No. 2 (2020): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.275 KB)

Abstract

Penelitian ini dilakukan untuk mengetahui pola peresepan obat antidiabetik pada pasien diabetes melitus tipe 2 di poli penyakit dalam RS “X” Sidoarjo periode Oktober-Desember 2019 sesuai dengan pedoman terapi ADA (American Diabetes Association) 2020. Penelitian ini dilakukan secara deskriptif yang bertujuan untuk menyajikan gambaran lengkap mengenai suatu keadaan secara objektif dengan metode total sampling dan pengambilan data secara retrospektif. Sampel dalam penelitian ini mengambil sejumlah 50 lembar resep yang masuk kriteria inklusi dan tercatat di pengumpul data meliputi nama obat, dosis obat, dan aturan pemakaiaan yang telah dianalisis. Berdasarkan data penelitian, dapat disimpulkan 72% pasien DM tipe 2 menggunakan terapi pengobatan OAD (Obat Anti Diabetik). Terapi pengobatan OAD tunggal sebesar 36% menjadi pilihan utama, OAD dari golongan Biguanide sebesar 26% adalah lini pertama dan agen farmakologi awal yang disukai. Terapi pengobatan OAD+Insulin sebesar 28%, dan pemilihan insulin long- acting sebesar 18%, sedangkan terapi pengobatan OAD kombinasi sediaan dari golongan biguanide+sulfonilurea sebesar 16%.
PENGARUH DUKUNGAN KELUARGA TERHADAP TINGKAT KEPATUHAN MINUM OBAT PASIEN TUBERKULOSIS DI PUSKESMAS WILAYAH BANJARMASIN TENGAH Mochammad Maulidie Alfiannor Saputera; Yugo Susanto; Soraya Soraya
Jurnal Insan Farmasi Indonesia Vol 4 No 2 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i2.812

Abstract

Patients suffering from tuberculosis often experience failure in therapy, due to non-adherence to taking medication. An important factor in improving medication adherence is the presence of family support. The purpose of this study was to determine the relationship between family support and medication adherence in pulmonary tuberculosis patients at the Public Health Center Central Banjarmasin area. The research method uses a cross sectional approach. The time of the study was carried out in May - July 2018. The sample of this study from January-April 2018 who treated pulmonary TB were 77 people. The sampling technique used was saturated sampling/total sampling, so the sample obtained was 33 people. The research instrument using a questionnaire was analyzed using correlation analysis using the Chi-Square test (a<0.05). Based on the results of the study showed that the results of the correlation test showed 0.000 <0.05. This shows that there is a strong relationship between family support and medication adherence in pulmonary tuberculosis patients at the Public Health Center Central Banjarmasin area.
Kualitas Hidup Pasien Hipertensi Dengan Penyakit Penyerta Di Poli Jantung RSUD Ratu Zalecha Martapura Riza Alfian; Yugo Susanto; Siti Khadizah
Jurnal Pharmascience Vol 4, No 1 (2017): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v4i1.5754

Abstract

ABSTRAK Hipertensi dengan penyakit penyerta adalah salah satu penyebab kematian nomor satu di dunia. Hal tersebut pasti akan membahayakan jiwa pasien dan menurunkan kualitas hidup pasien. Kualitas hidup merupakan indikator penting untuk menilai keberhasilan intervensi pelayanan kesehatan, baik dari segi pencegahan maupun pengobatan. Tujuan penelitian ini adalah untuk mengetahui gambaran kualitas hidup pasien hipertensi dengan penyakit penyerta gagal jantung dan hipertensi dengan penyakit penyerta diabetes melitus di poli jantung RSUD Ratu Zalecha Martapura. Penelitian ini merupakan penelitian deskriptif. Pengambilan data dilakukan secara prosfektif pada pasien rawat jalan di poli jantung selama periode Desember 2015 – Januari 2016. Subjek penelitian yang memenuhi kriteria inklusi sejumlah 71 orang yang terbagi atas 58 orang (82,36 %) pasien hipertensi dengan penyakit penyerta gagal jantung dan 13 orang (17,64 %) pasien hipertensi dengan penyakit penyerta diabetes melitus. Pengumpulan data dilakukan dengan melakukan wawancara mengunakan kuesioner Short Form 36 (SF 36). Hasil penelitian menunjukkan untuk 58 orang pasien hipertensi dengan penyakit penyerta gagal jantung 15 orang (25,86%) kualitas hidup baik, dan 43 orang (74,14%) kualitas hidup kurang baik, total skor kualitas hidup rata-rata yaitu 46,21 dengan nilai skor tiap dimensi yaitu fungsi fisik 48,71, fungsi emosi 64,9, fungsi sosial 50,25, kesehatan umum 44,11, keadaan fisik 31,9, keadaan emosi 36,23, dimensi nyeri 36,85, dan fatique 58,72. Sedangkan untuk 13 orang pasien hipertensi dengan penyakit penyerta diabetes melitus 9 orang (69,23 %) kualitas hidup baik dan 4 orang (30,77 %) kualitas hidup kurang baik, total skor kualitas hidup rata-rata yaitu 67,93 dengan nilai skor tiap dimensi yaitu fungsi fisik 69,54, fungsi emosi 86,00, fungsi sosial 75,96, kesehatan umum 49,68, keadaan fisik 63,46, keadaan emosi 66,67, dimensi nyeri 61,92, dan fatique 70,19. Berdasarkan hasil penelitian di poli jantung RSUD Ratu Zalecha Martapura dapat disimpulkan bahwa pasien hipertensi dengan penyakit penyerta gagal jantung mayoritas memiliki gambaran kualitas hidup yang kurang baik dan pasien hipertensi dengan penyakit penyerta diabetes melitus mayoritas memiliki gambaran kualitas hidup baik. Kata Kunci— Kualitas Hidup, Hipertensi dengan penyakit penyerta, ABSTRACT Hypertension with the followers disease is one of the main causes of death in the world. This problem certainly will endanger patients’ life and decrease their life quality. Life quality is an important indicator to measure the successful of health service intervention, either from prevention aspect or medical treatment aspect. The purpose of this research is to know the description of hypertension patient’s life quality with the followers disease heart failure and hypertension with the followers disease diabetes mellitus at polyclinic cardiology of Ratu Zalecha Hospital Martapura. This research is a descriptive research. Collecting data was conducted prosfectively on outpatient at poly cardiology from December 2015 until January 2016. The research subject who fulfilled the inclusive criteria is 71 patients. 58 patients (82.36%) have hypertension with the followers disease heart failure and 13 patients (17.64%) have and hypertension with the followers disease diabetes mellitus. Collecting data was done by doing interview using Short Form questioner (SF36). The result shows that from 58 hypertension patient with the followers disease heart failure, 15 patients of them (25.86%) have a good quality of life and 43 patients (74.14%) have a poor quality of life. The total average score of life quality is 46,21 with each detail aspect score like, physical function 48,71 emotional function 64.9, social function 50.25, general health 44.11, physical condition 31.9, emotional condition 36.23, painful aspect 36.85 and fatigue 58.72. Whereas for 13 hypertension patients with the followers disease diabetes mellitus, 9 (69.23%) of them have a good quality of life and 4 patients (30.77%) have a poor quality of life. The total average score of life quality is 67.93 with each detail aspect like; physical function 69.54, emotional function 86.00, social function 75.96, general health 49.68, physical condition 63.46, emotional condition 66.67, painful aspect 61,92 and fatigue 70,19. Based on the research at polyclinic cardiology of Ratu Zalecha Hospital Martapura it can be concluded that hypertension with the followers disease heart failure majority have poor quality of life and hypertension with the followers disease diabetes mellitus majority have good life of quality Keywords— Quality of life, Hypertension with complication, polyclinic cardiology.
Aktivitas Antibakteri Minyak Atsiri Kulit Jeruk Siam Banjar (Citrus reticulata) Terhadap Pertumbuhan Pseudomonas aeruginosa Dwi Rizki Febrianti; Yugo Susanto; Rakhmadhan Niah; Siti Latifah
Jurnal Pharmascience Vol 6, No 1 (2019): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i1.6070

Abstract

ABSTRAK Jeruk siam yang berkembang di Kalimantan Selatan telah dikukuhkan menjadi varietas unggul nasional dengan nama jeruk siam Banjar. Kulit jeruk belum dimanfaatkan secara optimal hanya dibuang sebagai limbah. Kulit jeruk mengandung beberapa senyawa salah satunya mengandung senyawa aktif minyak atsiri. Tujuan penelitian ini adalah untuk mengetahui adanya aktivitas antibakteri minyak atsiri kulit jeruk siam Banjar (Citrus reticulata) terhadap pertumbuhan Pseudomonas aeruginosa. metode penarikan minyak atsiri kulit jeruk siam Banjar menggunakan metode destilasi air. Uji aktivitas antibakteri dilakukan dengan menggunakan metode difusi cakram terhadap bakteri Pseudomonas aeruginosa. Hasil penelitian menunjukkan bahwa  minyak atsiri kulit jeruk siam Banjar diperoleh sebanyak 10 mL (0,58%), berwarna kuning, aroma khas jeruk, bentuk cair, rasa getir dan tidak ada noda transparan. Hasil penelitian uji aktivitas menunjukkan minyak atsiri kulit jeruk siam Banjar dapat menghambat pertumbuhan bakteri Pseudomonas aeruginosa. Pada volume 50 µL, 75 µL, dan 100 µL minyak atsiri kontrol positif (ciprofloxacin) sedangkan kontrol negatif (aqua pro injection). diameter zona bening disekitar cakam  dengan rata-rata diameter zona hambat yang dihasilkan beturut-turut 3,55 mm, 4,54 mm, 5,14 mm, 22,38 mm, dan 0 mm. Kata kunci: Kulit jeruk siam Banjar (Citrus reticulata), Minyak atsiri,  Pseudomonas aeruginosa. ABSTRACT Jeruk siam that develop in South Kalimantan have been confirmed as national superior varieties by the name of jeruk siam banjars. Citrus skin has not been used optimally only as waste. Orange peel contains several compounds, one of which contains active compounds of essential oils. The purpose of this study was to determine the antibacterial activity of essential oils of jerk siam banjars skin (Citrus reticulata) to the growth of Pseudomonas aeruginosa. method of withdrawal of jeruk siam banjars essential oil using a water distillation method. Antibacterial activity test was carried out using the disc diffusion method against the bacterium Pseudomonas aeruginosa. The results showed that 10 mL (0.58%) of essential oil from the jeruk siam banjars, yellow, orange aroma, liquid form, bitter taste, and no transparent stains. The results of the activity test showed that the essential oil of the skin of the jeruk siam banjars could inhibit the growth of the bacterium Pseudomonas aeruginosa. At the volume of 50 µL, 75 µL, and 100 µL of essential oil control positive (ciprofloxacin) while the negative control (aqua pro injection). the diameter of the clear zone around the paper disk with the average diameter of the inhibition zone produced was 3.55 mm, 4.54 mm, 5.14 mm, 22.38 mm and 0 mm respectively.Keywords: jeruk siam banjar (Citrus reticulata), essential oil, Pseudomonas aeruginosa.
Kualitas Hidup Pasien Hipertensi Dengan Penyakit Penyerta Di Poli Jantung RSUD Ratu Zalecha Martapura Riza Alfian; Yugo Susanto; Siti Khadizah
Jurnal Pharmascience Vol 4, No 2 (2017): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v4i2.5774

Abstract

Hipertensi dengan penyakit penyerta adalah salah satu penyebab kematian nomor satu di dunia. Hal tersebut pasti akan membahayakan jiwa pasien dan menurunkan kualitas hidup pasien. Kualitas hidup merupakan indikator penting untuk menilai keberhasilan intervensi pelayanan kesehatan, baik dari segi pencegahan maupun pengobatan. Tujuan penelitian ini adalah untuk mengetahui gambaran kualitas hidup pasien hipertensi dengan penyakit penyerta gagal jantung dan hipertensi dengan penyakit penyerta diabetes melitus di poli jantung RSUD Ratu Zalecha Martapura. Penelitian ini merupakan penelitian deskriptif. Pengambilan data dilakukan secara prosfektif pada pasien rawat jalan di poli jantung selama periode Desember 2015 – Januari 2016. Subjek penelitian yang memenuhi kriteria inklusi sejumlah 71 orang yang terbagi atas 58 orang (82,36 %) pasien hipertensi dengan penyakit penyerta gagal jantung dan 13 orang (17,64 %) pasien hipertensi dengan penyakit penyerta diabetes melitus. Pengumpulan data dilakukan dengan melakukan wawancara mengunakan kuesioner Short Form 36 (SF 36). Hasil penelitian menunjukkan untuk 58 orang pasien hipertensi dengan penyakit penyerta gagal jantung 15 orang (25,86%) kualitas hidup baik, dan 43 orang (74,14%) kualitas hidup kurang baik, total skor kualitas hidup rata-rata yaitu 46,21 dengan nilai skor tiap dimensi yaitu fungsi fisik 48,71, fungsi emosi 64,9, fungsi sosial 50,25, kesehatan umum 44,11, keadaan fisik 31,9, keadaan emosi 36,23, dimensi nyeri 36,85, dan fatique 58,72. Sedangkan untuk 13 orang pasien hipertensi dengan penyakit penyerta diabetes melitus 9 orang (69,23 %) kualitas hidup baik dan 4 orang (30,77 %) kualitas hidup kurang baik, total skor kualitas hidup rata-rata yaitu 67,93 dengan nilai skor tiap dimensi yaitu fungsi fisik 69,54, fungsi emosi 86,00, fungsi sosial 75,96, kesehatan umum 49,68, keadaan fisik 63,46, keadaan emosi 66,67, dimensi nyeri 61,92, dan fatique 70,19. Berdasarkan hasil penelitian di Poli Jantung RSUD Ratu Zalecha Martapura dapat disimpulkan bahwa pasien hipertensi dengan penyakit penyerta gagal jantung mayoritas memiliki gambaran kualitas hidup yang kurang baik dan pasien hipertensi dengan penyakit penyerta diabetes melitus mayoritas memiliki gambaran kualitas hidup baik. Kata Kunci: Kualitas Hidup, Hipertensi dengan penyakit penyerta
PENGUKURAN KUALITAS HIDUP PASIEN HEMODIALISIS GAGAL GINJAL KRONIK DI RSUD ULIN BANJARMASIN MENGGUNAKAN INSTRUMEN EQ5D Saftia Aryzki; Maudy Namirah Raudatullis Wanda; Yugo Susanto; Mochammad Maulidie Alfiannor Saputera; Aditya Maulana Perdana Putra; Karani Karani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.29 KB) | DOI: 10.36387/jiis.v4i1.230

Abstract

Chronic renal failure is a progressive and irreversible renal function disorder in which the body's ability to fail to maintain metabolism, fluid and electrolyte balance. Chronic kidney failure can interfere with the quality of life of patients, it is necessary to measure the quality of life of patients with chronic renal failure. Measuring the quality of life of patients with chronic renal failure using the Indonesian version of the EQ5D questionnaire. The purpose of this study was to determine the quality of life of chronic renal failure hemodialysis patients in RSUD Ulin Banjarmasin using the EQ5D instrument. This study is an observational study conducted prospectively. Data was collected by filling out the EQ5D questionnaire by all patients with chronic renal failure. The population of this study were chronic renal failure patients who underwent hemodialysis in Hemodialysis Outpatient Services at Ulin Banjarmasin Hospital in June-July 2018 as many as 360 patients and a sample of 207 patients who met the inclusion and exclusion criteria using non random sampling / non-probability sampling techniques accidental sampling. Based on the research that has been done in the Hemodialysis Outpatient Hospital Ulin Banjarmasin, it was found that the average quality of life was 0.792, with a quality of life ≥ 0.792 of 69 patients (33.33%) in the category of good quality of life and quality of life ≤ 0.792 138 patients (66.66%) in the poor quality of life category.
EFEKTIVITAS DAUN RAMANIA ASAL KALIMANTAN SELATAN UNTUK MENURUNKAN KADAR GULA DARAH Saftia Aryzki; Yugo Susanto
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.866 KB) | DOI: 10.36387/jiis.v4i2.342

Abstract

Ramania or Gandaria is a swamp plant in the area of South Kalimantan from one of the mango families that is not cultivated by the community, the types are diverse, including fruit size, flavor, and color. Ramania leaves have properties to reduce blood sugar levels. High blood sugar levels are a manifestation of diabetes mellitus. The purpose of this study was to determine the effectiveness of ramania leaf extract as a decrease in blood sugar levels with the oral glucose tolerance test (TTGO) method. This study was a true experimental with a pre-post test design with randomized control group design. The stages of the research method were carried out with a preliminary stage and an antidiabetic activity test stage with an oral glucose tolerance test (TTGO) method with Sprague Dawley strain male rats. The results of the research that have been done can be concluded that the extract of ramania leaf (Bouea macrophylla Griffith) can reduce the blood sugar levels of white mice (Mus muscullus) which are induced by alloxan. The dose used in this study was the lowest dose 0.455 mg / 200 kg body weight, treatment group 2 (P2) with moderate dose (usual use dose) 0.91 mg / 200 g body weight, and treatment group 3 (P3) with high dose 1, 82 mg / 200 g BW. Of the three groups approaching positive control, P3 with blood sugar levels after 14 days of treatment was 77.08 mg / dL and 77.79 mg / dL, respectively.
PENGARUH ALARM MINUM OBAT (AMINO) UNTUK MENINGKATKAN KEPATUHAN MINUM OBAT PASIEN HIPERTENSI Yusmaniar Yusmaniar; Yugo Susanto; Surahman Surahman; Riza Alfian
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.051 KB) | DOI: 10.36387/jiis.v5i1.395

Abstract

According to data from Riskesdas 2018 there was an increase in the prevalence of hypertension in Indonesia from 25.8% in 2013 to 34.1% in 2018. Inadequacy in taking medicine is one of the factor contributed. This research discusses the importance of the application of taking medication alarms for consultation taking medication and hypertension patients' blood pressure. The study was conducted using a quasi-experimental two group pretest posttest design. Observed data are the level of adherence and blood pressure. The study was conducted at 2 Banjarmasin Puskesmas. Data collection collected in the period August - October 2019. Research data were obtained by filling in the MARS questionnaire, while blood pressure data was taken from medical records. This study involved 25 samples each in the control and intervention groups. The intervention given was in the form of installing medication alarm in sample smartphone. The Wilcoxon Test to determine differences in the average category of level of adherence, and blood pressure samples at the beginning and end of the study. In the pre study 100% of the sample intervention group were at moderate medication adherence rates and in the post study it changed to 40% at moderate medication adherence levels and 60% at high medication adherence levels. Statistical test results show a significant increase in medication adherence. Systolic and diastolic blood pressure in the intervention group also experienced a significant decrease (p <0.05). The results of the study in the control group showed no increase in medication adherence and no significant decrease in blood pressure.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN RAMANIA (Bouea macrophylla Griffith) TERHADAP PENURUNAN KADAR GULA DARAH MENCIT PUTIH (Mus muscullus) YANG DIINDUKSI ALOKSAN Eka Kumalasari; Yugo Susanto; Maulida Yulia Rahmi; Dwi Rizky Febrianty
JCPS (Journal of Current Pharmaceutical Sciences) Vol 2 No 2 (2019): March 2019
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (480.593 KB)

Abstract

Diabetes mellitus is the disease of impaired metabolism that results when the pancreas does not produce enough insulin or when no body can effectively use insulin produced so as to cause an increased concentration of blood glucose. The treatment of diabetes mellitus can be an injection and tablet form which could result in the use of long term side effects. prevent it can use alternative treatment using Bouea macrophylla. Ramania is plants typical of South Kalimantan, active ingredients that is flavonoid and saponin which was is one of a substance efficacious as antidiabetic. This research from pre and post test with control group desain. Totaled white mice (Mus musculus) male to be used is 25 mices, devided into 5 groups is control negative (CMC Na 0,5%), control positif (Glibenklamid 3 mg/kgBB), extract 125 mg/kgBB, 250 mg/kgBB and 500 mg/kgBB. Observation agains in lowering blood glucose levels each groups test done on the day 7th and 14th after hiperglikemia induced by alloxan. Data the results of the analysis General Linear Model show that extract can in lowering blood glucose levels on white mice male that induced by alloxan significantly p<0,05. Doses of extract most effective in lowering blood glucose levels mice is 500 mg/kgBB.
INTERAKSI OBAT TERHADAP PERESEPAN ANTIPSIKOTIK PASIEN SKIZOFRENIA DIRUMAH SAKIT JIWA SAMBANG LIHUM KALIMANTAN SELATAN TAHUN 2011 Aristha Novyra Putri; Yugo Susanto; Difa Intannia
BORNEO JOURNAL OF PHARMASCIENTECH Vol 1 No 1 (2017): Borneo Journal of Pharmascientech
Publisher : Sekolah Tinggi Ilmu Kesehatan Borneo Lestari Banjarbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Skizofrenia merupakan penyakit kronik yang membutuhkan terapi antipsikotik jangka panjang sehingga sangat mungkin dalam proses terapi ditemukan permasalahan dalam penggunaan antipsikotik. Penelitian ini bertujuan untuk mengetahui persentase peresepan antipsikotik; persentase adanya potensi interaksi obat; persentase interaksi obat secara farmakokinetik, farmakodinamik, dan keduanya; dan persentase interaksi obat pada fase farmakokinetik, farmakodinamik, dan keduanya baik yang menaikkan maupun menurunkan efek. Penelitian ini merupakan penelitian observasional dengan rancangan deskriptif. Sampel dalam penelitian ini adalah rekam medik pasien Skizofrenia di Rumah Sakit Jiwa Sambang Lihum Kalimantan Selatan tahun 2011 yang memenuhi criteria inklusi, dimana jumlah sampel pada penelitian ini sebanyak 471. Hasil penelitian menunjukkan persentase peresepan antipsikotik haloperidol dan Chlorpromazine sebesar 37.99% dan 29.19%. Persentase potensi adanya interaksi obatdariterapisecarakombinasisebesar 69.6%,dimana persentase interaksi farmakokinetik, farmakodinamik, dan keduanya sebesar 2.96%, 3.45%,dan 93.6%.