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Pengaruh Senam Persadia Seri 1 terhadap Penurunan Gula Darah Puasa Pada Wanita Diabetes Melitus di Puskesmas Banyu Urip, Surabaya Farahiyah, Jihaan; Fatmaningrum, Widati; Mudjanarko, Sony Wibisono
Jurnal Ners Vol. 8 No. 1 (2024): APRIL 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v8i1.18911

Abstract

Diabetes Mellitus is characterized by high blood sugar levels. High blood sugar levels stimulate pancreatic beta cells to secrete insulin. In DM sufferers, physical activity is the main treatment for controlling blood sugar levels, one of which is the PERSADIA Series 1 Gymnastics which is a weight lifting exercise designed to increase muscle eccentricity which aims to increase glucose tolerance and reduce HbA1c. However, until now it is not known for sure the effect of PERSADIA Series 1 Gymnastics on reducing fasting blood sugar in women with Diabetes Mellitus. This study aims to determine and analyze the effect of PERSADIA Series 1 Gymnastics on reducing fasting blood sugar levels in women with Diabetes Mellitus. This research is a quasi-experimental type and was designed using a pre and post test group design with a control group. This study was followed by 60 women with Diabetes Mellitus and divided into 30 control groups who consumed OAD and carried out unstructured activities and 30 intervention groups who consumed OAD and did PERSADIA Series 1 Gymnastics which were carried out 3 times a week for a total of 12 times for 4 weeks with each training session lasting 40 minutes. Fasting blood sugar examination was carried out at the beginning and at the end of the study with subjects fasting at least 10 hours before the test. The research was processed using the SPSS 26 statistical test. Fasting blood sugar levels in both the control and intervention groups had an increase from pre-test GDP to post-test GDP. Statistically, there were no significant differences before and after the test in the control or intervention groups and also when the data between groups was compared with a p value = 0.403. PERSADIA Gymnastics Series 1 has not been able to significantly reduce fasting blood sugar levels in women with Diabetes Mellitus.
Effect of High Fat Diet on Body Weight, Visceral Fat Weight, and PPARG Expressions on Visceral Fat in Mice Melyana, Cantika Putri; Rejeki, Purwo Sri; Mudjanarko, Sony Wibisono; Herawati, Lilik; Al-Arif, Mohammad Anam
Folia Medica Indonesiana Vol. 57, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Obesity becomes a global epidemic nowadays. The high-fat diet is used as an alternative therapy for obesity. The optimal composition of a high-fat diet to reduce body weight is still unknown. This study aimed to determine which components of a high-fat diet can decrease body weight, visceral fat, and PPARG expression of visceral fat. This study was conducted at the Faculty of Veterinary Medicine, Universitas Airlangga, for three months by using a randomized post-test only control group design. Fifty male mice, 2-3 months old, 18-30 grams were adapted for one week given standard diet AIN93-M, then mice were divided into five groups, namely K1 (control group, 12% fat, 20% protein, 62% carbs); K2 (30% fat, 60% proteins, 0% carbs); K3 (45% fat, 45% protein, 0% carbs); K4 (60% fat, 30% protein, 0% carbs); and K5 (75% fat, 15% protein, 0% carbs). Bodyweight was measured before and after treatment, then the visceral fat and PPARG expressions were evaluated. Statistical comparisons were performed using Statistical Package for the Social Sciences (SPSS) software. After treatment, there were forty-three mice. The body weight and visceral fat weight of the mice with a high-fat diet were decreased. The most significant changes in body weight were in K4 with -9,60 ± 3,806 grams reduction. The bodyweight of mice in K5, slightly increased than K2-K4. This could be caused by the hormesis phenomenon. PPARG expressions decreased in groups with a high-fat diet but increased in K5. The composition of a high-fat diet in group K4 was the most optimal to decrease the body weight, visceral fat, and PPARG expressions in mice
Mortality among Heart Failure Patients in the Presence of Cachexia , Andrianto; Karman, Ula Nur Pramesti; Mudjanarko, Sony Wibisono; Ardiana, Meity; Hermawan, Hanestya Oky
Folia Medica Indonesiana Vol. 59, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: • Around 38.8% of heart failure patients with cachexia died during the 180-1,876-day follow-up period. • Cachexia increases the risk of mortality in heart failure patients. Abstract: Despite the fact that obesity has long been recognized as a risk factor for cardiovascular disease, the mortality rate of heart failure (HF) patients with cachexia is still high. Several studies have been conducted to investigate the association between cachexia and mortality in HF patients. However, the research results vary, as do the diagnostic criteria employed to assess cachexia. This meta-analysis aimed to conclusively summarize the association between cachexia and mortality in HF patients. The data were obtained from prospective or retrospective cohort studies with full texts in English or Indonesian and keywords related to "cachexia," "heart failure," and/ or "mortality". Studies that did not assess mortality in HF patients with cachexia and had no full text accessible were omitted. A literature search was conducted through four databases (PubMed, Web of Science, Scopus, and SAGE Journals) using keywords, reference searches, and/ or other methods on April 2022 in accordance with the Preferred Reported Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data from the selected studies were presented and analyzed using qualitative and quantitative synthesis methods. The Newcastle-Ottawa Scale (NOS) was used to assess the risk of bias in the selected cohort studies. The qualitative synthesis contained nine studies, whereas the quantitative synthesis (meta-analysis) included six studies. Cachexia was found in 16.0% of the 4,697 patients studied. During the 180-1,876-day follow-up period, 33.0% of the patients died, with a mortality rate of 38.8% among the patients with cachexia. The pooled analysis revealed cachexia to be a significant predictor of mortality in HF patients (hazard ratio (HR)=3.84; 95% CI=2.28-6.45; p<0.00001), but with significant heterogeneity (p<0.00001; I2=88%). In conclusion, cachexia worsens HF prognosis.
Pemanfaatan Video Call sebagai Sarana Penyutradaraan Jarak Jauh dalam Drama Radio “Dendam” Susantio, Karin Ramadhani; Wibisono, Sony
Jurnal Ilmiah Multimedia dan Komunikasi JIMK Vol. 6 No. 2, Desember 2021
Publisher : Sekolah Tinggi Multi Media "MMTC" Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56873/jimk.v6i2.138

Abstract

Wabah Covid-19 yang mengharuskan seluruh masyarakat Indonesia untuk membatasi pertemuan langsung agar tidak terpapar oleh virus. Hal tersebut membuat pekerja kreatif yang biasa berproses secara langsung harus memutar otak. Tulisan ini berupaya memaparkan upaya penulis sebagai sutradara dalam menyutradarai sebuah drama radio secara jarak jauh. Saat ini kehidupan manusia telah diuntungkan dengan teknologi yang mendukung untuk penyutradaraan drama radio jarak jauh, salah satunya adalah video call. Teknologi menjadi sarana untuk menerapkan teori penyutradaraan pemain drama radio. Adapun teori yang dipilih untuk mencapai pendalaman karakter digunakan teori kesanggupan kata, dan teknik vokal. Pengarahan (directing) kepada seorang pengisi suara melalui sarana video call melaui aplikasi WhatsApp dan Zoom. Berdasarkan proses produksi yang telah dijalani, teknik penyutradaraan jarak jauh drama radio dengan sarana video call ternyata bisa terwujud. Hal ini menjadi salah satu alternatif cara memproduksi drama radio ketika masyarakat masih dalam kondisi keterbatasan karena pandemi covid-19.
Challenges in the Diagnosis and Management of Adrenal Insufficiency Febri Kurniawati; Sony Wibisono Mudjanarko; Soebagijo Adi Soelistijo; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.9

Abstract

Adrenal insufficiency (AI) is a rare endocrine condition. Primary adrenocortical insufficiency, or Addison diseases reduces the production of crucial hormones, including glucocorticoids, mineralocorticoids, and adrenal androgens. Due to the lack of proper cortisol response in adrenal crisis, it can be life-threatening during times of stress, emphasizing the need for a timely diagnosis. Despite this, diagnosing and managing AI still presents significant challenges. We report the case of a middle-aged woman who presented with complaints of weight loss, abdominalpain, lethargy, hyperpigmentation of the skin and mucosa, and a history of repeated hospitalizations for nausea, vomiting, dehydration, and hypovolemia. During the patient's previous hospitalization, Addison's crisis was suspected, and methylprednisolone therapy was administered, rendering the cortisol and ACTH assays inaccurate. The patient's condition subsequently improved. The subsequent monitoring revealed low cortisol levels, but an ACTH stimulation test was unavailable. The presence of pulmonary tuberculosis was indicated by a positive chest X-ray and IFN-Gamma Release Assay (IGRA) test. With a history of repeated hospitalizations, suspected Addison's crisis, hypoglycemia, mineralocorticoid involvement (hypotension, hyponatremia), and the presence of hyperpigmentation, a clinical diagnosis of primary adrenal insufficiency was made with limited conditions and testing tools. The patient was given anti-tuberculosis treatment and the lowest dose of hydrocortisone required to control the disease without causing side effects.
Co-Authors , ANDRIANTO AGUNG PRANOTO Agung Pranoto Agustianto, Rafiv Fasya Akbar, Royhan Al arif, Mohammad Anam Andrianto Andrianto Andrianto Ardiany, Deasy Ariana, Audy Meutia Ariep Jaenul Arifoel Hajat Askandar Tjokroprawiro Audy Meutia Ariana Bambang Hermanto Bambang Purwanto Budi Prasetyo Cahyanti, Reni Ika Cantika Putri Melyana Chandra Adi Irawan Primasatya Chandra Irwanadi, Chandra Damayanti Tinduh Desi Rianti Rahmadhani Dian W Astuti Emmy Amalia Farahiyah, Jihaan Fauqa Arinil Aulia Febri Kurniawati Ferdy Royland Marpaung Gusti Agung Ayu Ira Kencana Dewi Hanestya Oky Hermawan Hanestya Oky Hermawan, Hanestya Oky Hendra Gunawan Herawati, Fauna HERAWATI, LILIK Hermifa Dwi Aninnaimah Hermina Novida, Hermina Hertin, Revita Imam Subadi Indah Wulandari Islam, Ichsani Jayawarsa, A.A. Ketut Karman, Ula Nur Pramesti Khoirun Nisa Komaratih, Evelyn Kurnia Alisaputri Kusnanto Kusnanto Laylatul Fitriah Mukarromah Lefi, Achmad Leonita Anniwati Maftuchah Maftuchah Martha Kurnia Kusumawardani Martiniani, Endang Mas'adah Mas'adah Meity Ardiana Melyana, Cantika Putri Mochamad Wildan mulyono, Sidik Natasha Tiara Bernadette Nur Sulastri Nuvus, Alviyatul Ainin Pawana, I Putu Alit Permana, Putu Bagus Dharma Prabowo, Gwenny Ichsan Primasatya, Chandra Adi Irawan Purwati Rafsanjani, M. Hashemi Rejeki, Purwo Sri Rifki Esa Syahnarki Safira Raissa Dwi Putri SATRIYAS ILYAS Setiawan, Antonius Sidarti Soehita Soebroto, Heroe Soelistijo, Soebagijo Adi Sri Lestari Utami Suksmi Yitnamurti Surdiana Susantio, Karin Ramadhani Thomas Jatiman Titin Puspitasari Ula Nur Pramesti Karman Wibowo, Aryo Widati Fatmaningrum Widyanrika, Farahdiva Audrey Wigati, Kristanti Wanito Winna Adelia Amru Yuli Indah Kurnia