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Journal : Agrointek

KARAKTERISASI NILAI IC50 DAN KADAR KURKUMIN PADA TABLET EFFERCVESCENT EKSTRAK KUNYIT YANG DIPERKAYA VITAMIN C Arief Rakhman Affandi; Ary Susatyo Nugroho; Umar Hafidz Asyari Hasbullah
AGROINTEK Vol 17, No 2 (2023)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v17i2.13040

Abstract

During the pandemic, nutraceuticals are needed to boost immunity. Indonesia is one of the countries that has the potential to produce nutraceutical goods based on rhizomes like ginger, turmeric, temulawak, and other types of rhizomes. These rhizomes have been used for medicinal purposes for thousands of years. This refresher contains significant health-promoting effects. Turmeric contains several components of active compounds that can act as antioxidant compounds and increase body immunity. Effervescent tablets are one sort of food product that could be made utilizing turmeric as an ingredient. The purpose of this study was to develop a formula for effervescent tablets that make use of turmeric extract and are mixed with vitamin C, which is known also to aid increase body immunity and other bodily health functions. The design is a Complete Randomized Design (RAL) Factorial pattern employing two factors: turmeric extract (30 40 %b/b) and vitamin C (5, 10, 15 %b/b). The experimental responses that were used were the solubility time, the pH value of the solution, and the antioxidant capacity (IC50 value). An increase in vitamin C concentration is associated with a corresponding rise in solution pH, which, according to SPSS analysis, reaches a maximum value of 3.96. Effervescent tablets with 40% turmeric extract and 15% vitamin C have the lowest IC50 value (0.89 mg/ml). The result represents the product's antioxidant potential to ward off free radicals in a reasonable level. This formula also has the quickest solubility time when compared to other formulae for the fabrication of effervescent tablets, with a time range of 190 seconds for 1 tablet (± 3 grams).
Co-Authors Afni Lailiyah Afwah, Afwah Ari Widyaningrum, Ari Arief Rakhman Affandi Aries Tika Damayani Aries Tika Damayani, Aries Tika Astin Kurniawati Atip Nurwahyunani, Atip Berlin, Ivonne Susana Boedhi Hendrarto Boedhi Hendrarto . Boedhi Hendrarto ., Boedhi Hendrarto Cahyani, Dwi Kurnia Chabibah, Chabibah Dewanti, Gestari Ayu Dewi Arum Budianti Dinar Mega Ayu Dwinanda Ary Nugroho Dyah Ayu Widyastuti Eka Sari Setianingsih Eka Sari Setianingsih, Eka Sari Eko Retno Mulyaningrum Eko Retno Mulyaningrum Eko Retno Mulyaningrum Elsa Septiani Rintho Miharjo Endah Rita Sulistya Dewi Endah Rita Sulistya Dewi Endah Rita Sulistya Dewi Erlinawati, Banundari Eti Indriyati Fenny Roshayanti Fenny Roshayanti Fenny Roshayanti Fenny Roshyanti Fibria Kaswinarni Fibria Kaswinarni Filia Prima Artharina Hayat, Muhammad Syaiful Hayat, Muhammad Syaipul Ikha Listyarini Indriasari, Ika Joko Siswanto Joko Siswanto Khusnul Fajriyah Khusnul Fajriyah Klarisa Aulia Rahma Klarisa Aulia Rahma Rahma Lina Ari Suharyani M. Anas Dzakiy Mahfudah, Salis Maria Ulfa Maria Ulfah Maria Ulfah Maria Ulfah . Mefi Andriani Mei Fita Asri Untari Muh. Dzulfiqar Joddy Al-Mulk Muhammad Saipul Hayat Muhammad Syaipul Hayat Muhammad Syaipul Hayat Nila Sari Dewi Nizaruddin Novaris, Riftian Nugroho, Dwinanda Ary Nugroho, Unggung Eri Nur Hikmah Nurul Fadlilah Nurul Qomariyah Oka Harmas Theana Prasetiawati, Ervina Titi Prasetiyo Prasetiyo Prasetiyo Prasetiyo Prasetyo Anggun Pribadi Prasetyo Prasetyo Prasetyo Utomo, Yudha Eko Priyono, Slamet Putri Ayu Lestari Rahma, Klarisa Aulia Reni Astuti Widyowanti Retnoningsih, Ayu Ririn Rusmiati Rivanna Citraning Rahmawati Riyadhotus Sholihah Riyadhotus Sholihah Rosyida Rosyida Rusmiati, Ririn Sentot Purboseno Shalihuddin Djalal Tanjung Siti Patonah Sri Rahmawati Sukamto Sukamto Sulistya Budiwati Syaiful Hayat, Muhammad Theana, Oka Harmas Umar Hafidz Asyari Hasbullah Utami, Diantri Widia Noviani