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All Journal Majalah Obat Tradisional JMM (Jurnal Masyarakat Mandiri) Jurnal Kreativitas PKM Journal of Midwifery and Nursing MEDIA INFORMASI Jurnal Ilmu Kefarmasian Indonesia Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian International Journal of Research in Community Services Jurnal Abdimas Kartika Wijayakusuma Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Jurnal Pengmas Kestra (JPK) Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat (Jupemas) Ardhi: Jurnal Pengabdian dalam Negri Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Sasambo: Jurnal Abdimas (Journal of Community Service)
Sutrisno, Entris
Faculty Of Pharmacy, Bhakti Kencana University, Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Science Midwifery

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Evaluation of antihypertensive drug use in preeclampsia and eclampsia patients in the inpatient room of Bandung Regency Hospital Sutrisno, Entris; Selifiana , Nita; Sodik , Jajang Japar; Agustin, Ia Nurfauziah
Science Midwifery Vol 12 No 4 (2024): October: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i4.1703

Abstract

Indonesia is one of the third highest developing countries in ASEAN with maternal mortality rate (MMR) and infant mortality rate (IMR). One of the three main causes of pregnancy-related maternal deaths is hypertension during pregnancy. It is very important to get rational antihypertensive therapy immediately in order to maintain normal blood pressure. This study aims to determine the profile of the use and rational use of antihypertensive drugs in preeclampsia and eclampsia patients in the Inpatient Room of Bandung Regency Hospital. The study was conducted observational with retrospective data collection. Samples were taken by random sampling which met the inclusion criteria for the period January-December 2021. The rationality of antihypertensive drug use is based on the 2019 American College of Obstetrics and Gynecologists and PIONAS guidelines. There were 78 medical records that met the criteria. The characteristics of the majority of patients aged 21-35 years (64%) with a gestational age of 28-40 weeks (97%) and the antihypertensive drug therapy that was widely used was nifedipine (56%). The percentage of rational use of antihypertensive drugs showed the right indication (100%), the right drug (95%), the right dose (100%), and the right frequency (100%).
Nanophytosome delivery system and in vivo test of combination of binahong leaf extract (Andredera cordifolia) and bay leaf (Syzygium polyanthum) as a diabetic wound healer Saifurrohman, Arip; Jafar, Garnadi; Sutrisno, Entris; Senjaya, Fathurahman Ari
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2326

Abstract

This study aimed to develop and characterize a nanophytosome system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia), and to evaluate its wound healing activity through in vivo study. The extracts were prepared by maceration using 96% ethanol and characterized through phytochemical screening and LC-MS/MS analysis. Nanophytosomes were formulated using phospholipid complexes with variations of surfactants, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index, zeta potential, and entrapment efficiency. The results showed that particle size ranged from 16.30 to 927.18 nm, with the smallest size observed in Tween 80-based formulation. The polydispersity index ranged from 0.20 to 0.86, indicating better homogeneity in Tween 80 systems. Zeta potential values ​​were in the range of −6 to −17 mV, suggesting moderate stability. Entrapment efficiency was high in all formulations (92.5–97.3%), with the highest value observed in Cremophor-based formulation. In vivo evaluation demonstrated that the nanophytosome significantly accelerated wound healing compared to control groups, as indicated by faster wound contraction and improved tissue regeneration. In conclusion, the nanophytosome system enhanced the physicochemical properties and delivery of bioactive compounds, showing potential as an effective therapeutic approach for wound healing.
Co-Authors Agustin, Ia Nurfauziah Ajeng Pramesti Amida S Sarbini Amini, Nadia Ushfuri Anbar Fatin, Mia Nisrina Ani Anggriani Ani Anggriani, Ani Aris Suhardiman Arsila, Nurlutfita Astira Kosmawati Budi, Hermawan Setya Budiana, Wempi Cici Valiani Desi Trisiani Destia Tresna Prima Dewi Mardiyah Diana Ulfah Eki Pratidina Fajarrini, Uvika Nurul Fatmawati, Fenti Fenti Fatmawati Fitriani Mardiana Garnadi Jafar, Garnadi Helen Fitri Novianti Herdiana, Geralda Bintang Ida Lisni Istiqomah, Aulia Nurfazri Jajang Japar Sodik Kania Fajarwati Khotimah, Nur Intan Husnul Madinatul Munawaroh Maharani, Ilmi Intan Manaf, Manaf Marita Kaniawati Mia Nisrina A Muslim, Dede Nur Aziz Nadia Ushfuri Amini Nazarul Mastura Nenden Ufiyani Noviyanti, Eva Pasha, ED. Yunisa Mega Purwaniati, Purwaniati R. Awaludin Nazal N Rahayu, Sri Mulyati Rahma Fatwia Ratu Fania Aprilyanti Roni, Asep Ruswanti, Seffi Saifurrohman, Arip Salsha Rosilopya Salwa Siti Balqis Sarbini, Amida S Saskia, Puti Bela Selifiana , Nita Selifiana, Nita Selvi Restiani Senjaya, Fathurahman Ari Sephia Indah Lutpiah Siti Balqis, Salwa Siti Rokmah Suherdin Suryanti, Wulan Maulani Susilawati, Elis Sutriyawan, Agung Valiani, Cici Vitniawati, Vina Wempi Budiana Yani Mulyani Yani Mulyani Zaelani, Diki Ziska, Rahma