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All Journal Majalah Obat Tradisional JMM (Jurnal Masyarakat Mandiri) Jurnal Kreativitas PKM Journal of Midwifery and Nursing MEDIA INFORMASI Jurnal Ilmu Kefarmasian Indonesia Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian International Journal of Research in Community Services Jurnal Abdimas Kartika Wijayakusuma Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Jurnal Pengmas Kestra (JPK) Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat (Jupemas) Ardhi: Jurnal Pengabdian dalam Negri Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Sasambo: Jurnal Abdimas (Journal of Community Service)
Sutrisno, Entris
Faculty Of Pharmacy, Bhakti Kencana University, Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Study on the use of antibiotics in patients with upper respiratory tract infections (URI) at a public health center in karawang regency Ida Lisni; Nurlutfita Arsila; Entris Sutrisno
Journal of Midwifery and Nursing Vol. 7 No. 2 (2025): May: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v7i2.6028

Abstract

Respiratory Tract Infection is an infection affecting the respiratory tract structures, damaging the gas exchange process from the nose to the alveoli, lasting up to 14 days, and is typically contagious. Upper Respiratory Tract Infection (URTI) is a disease with a high prevalence, causing nearly 4 million deaths each year. This study aims to determine the pattern of antibiotic use and the appropriateness of drug administration based on indications, dosage, and frequency at a health center in Karawang Regency. The research was conducted retrospectively from patient medical records and analyzed quantitatively. The results show that 121 patients in this study used antibiotics. Based on gender, 52.89% were male and 47.10% were female. The most common age category was early adulthood (26-35 years) at 26.44%. The antibiotics used were Amoxicillin (57.02%), Cefixime (22.31%), and Cotrimoxazole (20.66%). The accuracy of drug use with appropriate indications was 100%, the appropriateness of dosage was 99.17%, and the appropriateness of frequency was 100%.
Nanophytosome delivery system and in vivo test of combination of binahong leaf extract (Andredera cordifolia) and bay leaf (Syzygium polyanthum) as a diabetic wound healer Arip Saifurrohman; Garnadi Jafar; Entris Sutrisno; Fathurahman Ari Senjaya
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2326

Abstract

This study aimed to develop and characterize a nanophytosome system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia), and to evaluate its wound healing activity through in vivo study. The extracts were prepared by maceration using 96% ethanol and characterized through phytochemical screening and LC-MS/MS analysis. Nanophytosomes were formulated using phospholipid complexes with variations of surfactants, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index, zeta potential, and entrapment efficiency. The results showed that particle size ranged from 16.30 to 927.18 nm, with the smallest size observed in Tween 80-based formulation. The polydispersity index ranged from 0.20 to 0.86, indicating better homogeneity in Tween 80 systems. Zeta potential values ​​were in the range of −6 to −17 mV, suggesting moderate stability. Entrapment efficiency was high in all formulations (92.5–97.3%), with the highest value observed in Cremophor-based formulation. In vivo evaluation demonstrated that the nanophytosome significantly accelerated wound healing compared to control groups, as indicated by faster wound contraction and improved tissue regeneration. In conclusion, the nanophytosome system enhanced the physicochemical properties and delivery of bioactive compounds, showing potential as an effective therapeutic approach for wound healing.
Potensi Farmakologi Tanaman Kratom (Mitragyna speciosa Korth.): Review Wulan Maulani Suryanti; Purwaniati Purwaniati; Entris Sutrisno
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 1 (2026): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i1.34965

Abstract

Indonesia sebagai negara tropis memiliki keragaman hayati yang melimpah, termasuk tanaman kratom (Mitragyna speciosa Korth.) yang dikenal memiliki aktivitas farmakologis potensial. Studi ini bertujuan untuk meninjau aktivitas farmakologis kratom melalui kajian literatur deskriptif dari berbagai publikasi ilmiah yang relevan. Metode yang digunakan adalah kajian literatur dengan mencari artikel-artikel yang memuat informasi tentang aktivitas farmakologi kratom. Hasil kajian menunjukkan bahwa kratom memiliki beragam aktivitas farmakologis, antara lain antinosiseptif, antikanker, antimikroba, antidiabetes (penghambatan α-glukosidase), analgesik, ansiolitik, antiinflamasi, dan antidepresan. Senyawa utama dalam kratom, seperti mitraginin dan 7-hidroksimitraginin, memiliki peran penting dalam aktivitas terapeutiknya. Namun, meskipun demikian, bukti ilmiah yang ada masih terbatas, terutama dalam hal evaluasi preklinis dan klinis yang terstandarisasi. Penggunaan kratom juga masih menimbulkan kekhawatiran terkait potensi ketergantungan dan efek psikoaktif yang berisiko. Kesimpulannya, kratom memiliki potensi besar sebagai terapi alternatif, namun penggunaan kratom harus disertai dengan penelitian lebih lanjut untuk mengevaluasi keamanan jangka panjang, dosis yang optimal, dan regulasi yang tepat.
Pengaruh Edukasi dan Konseling Apoteker terhadap Kepatuhan dan Kualitas Hidup Pasien Kanker Payudara: Literatur Review Hermawan Setya Budi; Entris Sutrisno
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.982

Abstract

Pharmacist-led interventions, particularly through education and counselling, play an essential role in supporting treatment adherence and improving the quality of life of breast cancer patients. This article aims to review the influence of pharmacist interventions—such as medication counseling, side effect management, and adherence monitoring—on patient understanding, psychological aspects, and quality-of-life indicators. Results from various experimental studies and randomized controlled trials suggest that structured pharmacist interventions can improve patient understanding, reduce anxiety, and support adherence to long-term therapies such as tamoxifen and chemotherapy. Improvements were also observed in various domains of quality of life, including physical, emotional, and social functioning. However, some studies show inconsistent results, especially in terms of statistical differences in changes in quality of life, which may be due to factors such as sample size, duration of intervention, or other variables, including family support and disease prognosis. Overall, the involvement of pharmacists is an integral part of oncology care, serving as both an educator and a long-term therapy companion.
Co-Authors Agustin, Ia Nurfauziah Ajeng Pramesti Amida S Sarbini Amini, Nadia Ushfuri Ani Anggriani Ani Anggriani, Ani Arip Saifurrohman Aris Suhardiman Astira Kosmawati Budiana, Wempi Cici Valiani Destia Tresna Prima Dewi Mardiyah Diana Ulfah Eki Pratidina Fajarrini, Uvika Nurul Fajarwati, Kania Fathurahman Ari Senjaya Fatmawati, Fenti Fenti Fatmawati Fitriani Mardiana Garnadi Jafar, Garnadi Helen Fitri Novianti Herdiana, Geralda Bintang Hermawan Setya Budi Ida Lisni Ida Lisni Istiqomah, Aulia Nurfazri Jajang Japar Sodik Khotimah, Nur Intan Husnul Madinatul Munawaroh Maharani, Ilmi Intan Manaf, Manaf Marita Kaniawati Mia Nisrina Anbar Fatin Muslim, Dede Nur Aziz Nadia Ushfuri Amini Nazarul Mastura Nenden Ufiyani Noviyanti, Eva Nurlutfita Arsila Pasha, ED. Yunisa Mega Purwaniati, Purwaniati - R. Awaludin Nazal N Rahayu, Sri Mulyati Rahma Fatwia Ratu Fania Aprilyanti Roni, Asep Ruswanti, Seffi Salsha Rosilopya Salwa Siti Balqis Sarbini, Amida S Saskia, Puti Bela Selifiana , Nita Selifiana, Nita Selvi Restiani Sephia Indah Lutpiah Siti Balqis, Salwa Siti Rokmah Suherdin Susilawati, Elis Sutriyawan, Agung Trisiani, Desi Valiani, Cici Vitniawati, Vina Wulan Maulani Suryanti Yani Mulyani Yani Mulyani Zaelani, Diki Ziska, Rahma