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All Journal Majalah Obat Tradisional JMM (Jurnal Masyarakat Mandiri) Jurnal Kreativitas PKM MEDIA INFORMASI Jurnal Ilmu Kefarmasian Indonesia Science Midwifery Lumbung Farmasi : Jurnal Ilmu Kefarmasian International Journal of Research in Community Services Jurnal Abdimas Kartika Wijayakusuma Jurnal Abdi Masyarakat Kita Sciences of Pharmacy Jurnal Pengmas Kestra (JPK) Jurnal Farmasi Indonesia Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat (Jupemas) Ardhi: Jurnal Pengabdian dalam Negri Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Galenika Sasambo: Jurnal Abdimas (Journal of Community Service)
Sutrisno, Entris
Faculty Of Pharmacy, Bhakti Kencana University, Bandung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Comparative Glycemic Effectiveness of Long- and Rapid-Acting Insulin in Patients with Type 2 Diabetes Mellitus Sutrisno, Entris; Kaniawati, Marita; Maharani, Ilmi Intan; Sodik, Jajang Japar
Sciences of Pharmacy Volume 4 Issue 4
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0404502

Abstract

Insulin therapy is essential for managing type 2 diabetes mellitus (T2DM), particularly in patients who fail to achieve glycemic targets with oral antidiabetic agents. Long-acting insulin is primarily used to control basal glucose levels, while rapid-acting insulin targets postprandial hyperglycemia. However, comparative real-world evidence regarding their effectiveness on glycated hemoglobin (HbA1c) and fasting blood glucose (FBG) remains limited. This study aimed to evaluate and compare the effectiveness of long-acting and rapid-acting insulin in improving HbA1c and FBG levels among patients with T2DM. A retrospective before–and–after observational study was conducted involving 122 T2DM patients treated at the outpatient unit of Majalaya Regional General Hospital between January and December 2024. Patients received either long-acting insulin (e.g., insulin glargine) or rapid-acting insulin (e.g., insulin lispro and insulin aspart) as monotherapy. Changes in HbA1c and FBG before and after therapy were analyzed using paired t-tests or Wilcoxon signed-rank tests. Clinical effectiveness was defined according to American Diabetes Association criteria as a reduction of ≥1% in HbA1c or ≥30 mg/dL in FBG. Insulin therapy significantly reduced HbA1c (−7.77 ± 3.09, p < 0.001) and FBG levels (Z = −5.53, p < 0.001). Based on ADA criteria, 90.3% of patients achieved an effective reduction in HbA1c, while 43.5% achieved an effective reduction in FBG. Insulin lispro and insulin glargine showed the highest HbA1c-based effectiveness (100%), whereas FBG-based effectiveness varied across formulations. Insulin therapy significantly improves long-term and short-term glycemic control in T2DM patients, with insulin lispro and insulin glargine demonstrating the most consistent effectiveness.
Gambaran Pola Penggunaan Antipsikotik Pada Pasien Skizofrenia Di Ruang Rawat Inap Rumah Sakit Jiwa Provinsi Jawa Barat Sutrisno, Entris; Mulyani, Yani; Sodik, Jajang Japar
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.344

Abstract

Indonesia experiences an alarming increase in mental disorder cases annually. In 2019, the World Health Organization reported that over 20 million individuals worldwide suffer from schizophrenia. Antipsychotic medications are the preferred treatment option for schizophrenia, as they help alleviate psychotic symptoms and reduce the likelihood of developing the disorder. This study aimed to describe the use of antipsychotic drugs in patients with schizophrenia in the inpatient ward of the Mental Hospital of West Java Province. The study employed a non-experimental, descriptive design with retrospective data collection. Secondary data were used for analysis. The research focused on 194 medical records of patients who received antipsychotic treatment between January and December 2020. The study revealed that 56.19% of prescribed antipsychotic drugs were combination medications, while 43.81% were single drugs. The most common combination of antipsychotic drugs was haloperidol-clozapine, accounting for 36.60% of the prescriptions, and risperidone, a single drug, comprised 19.67% of the prescriptions.
Pendekatan Partisipatif dalam Edukasi Manajemen Stres: Integrasi Aromaterapi di Lingkungan SMK Bhakti Kencana Majalaya Budiana, Wempi; Fatmawati, Fenti; Sutrisno, Entris; Ziska, Rahma; Anbar Fatin, Mia Nisrina; Sodik, Jajang Japar; Ruswanti, Seffi
Jurnal Abdimas Kartika Wijayakusuma Vol 7 No 1 (2026): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v7i1.1192

Abstract

Kesehatan mental remaja merupakan salah satu perhatian utama dalam bidang kesehatan masyarakat, dengan stres sebagai faktor risiko yang signifikan. Program pengabdian masyarakat ini bertujuan untuk memberikan edukasi kepada siswa-siswi SMK Bhakti Kencana Majalaya mengenai manajemen stres menggunakan aromaterapi. Program ini menggunakan pendekatan partisipatif berbasis komunitas, dengan melibatkan kolaborasi antara Fakultas Farmasi Universitas Bhakti Kencana dan pihak sekolah SMK Bhakti Kencana Majalaya. Intervensi yang dilakukan berupa edukasi kesehatan interaktif tentang kesehatan mental dan manajemen stres, dilanjutkan dengan workshop praktik langsung membuat produk aromaterapi sederhana. Sebanyak tiga puluh dua siswa dari Jurusan Farmasi berpartisipasi aktif dalam program ini. Hasil program menunjukkan adanya perubahan positif pada pengetahuan dan tingkat stres siswa. Rata-rata skor pengetahuan tentang stres dan manajemen diri meningkat dari 60% ( pre-test) menjadi 95% (post-test). Temuan kualitatif menunjukkan adanya transfer pengetahuan ke dalam perilaku, dimana siswa mempraktikkan teknik relaksasi serta melaporkan kualitas tidur yang lebih baik setelah menggunakan diffuser aromaterapi. Keberhasilan program ini menyoroti efektivitas pendidikan kesehatan berbasis sekolah yang partisipatif beserta intervensi komplementer dalam menurunkan stres di kalangan remaja. Tingkat kepuasan yang tinggi (90%) di antara siswa mencerminkan metode pembelajaran yang menarik dan interaktif yang digunakan. Program ini memberikan kontribusi bagi bertambahnya bukti yang mendukung intervensi holistik berbasis sekolah untuk kesehatan mental remaja, serta memberikan keterampilan praktis dalam pengelolaan stres. Program di masa mendatang disarankan untuk mereplikasi pendekatan ini di sekolah lain, dengan memasukkan komponen inovatif dan tindak lanjut jangka panjang untuk menilai keberlanjutan dampak program.
Nanophytosome delivery system and in vivo test of combination of binahong leaf extract (Andredera cordifolia) and bay leaf (Syzygium polyanthum) as a diabetic wound healer Saifurrohman, Arip; Jafar, Garnadi; Sutrisno, Entris; Senjaya, Fathurahman Ari
Science Midwifery Vol 14 No 1 (2026): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v14i1.2326

Abstract

This study aimed to develop and characterize a nanophytosome system containing combined extracts of bay leaf (Syzygium polyanthum) and binahong leaf (Anredera cordifolia), and to evaluate its wound healing activity through in vivo study. The extracts were prepared by maceration using 96% ethanol and characterized through phytochemical screening and LC-MS/MS analysis. Nanophytosomes were formulated using phospholipid complexes with variations of surfactants, followed by homogenization and sonication. The formulations were evaluated for particle size, polydispersity index, zeta potential, and entrapment efficiency. The results showed that particle size ranged from 16.30 to 927.18 nm, with the smallest size observed in Tween 80-based formulation. The polydispersity index ranged from 0.20 to 0.86, indicating better homogeneity in Tween 80 systems. Zeta potential values ​​were in the range of −6 to −17 mV, suggesting moderate stability. Entrapment efficiency was high in all formulations (92.5–97.3%), with the highest value observed in Cremophor-based formulation. In vivo evaluation demonstrated that the nanophytosome significantly accelerated wound healing compared to control groups, as indicated by faster wound contraction and improved tissue regeneration. In conclusion, the nanophytosome system enhanced the physicochemical properties and delivery of bioactive compounds, showing potential as an effective therapeutic approach for wound healing.
Co-Authors Agustin, Ia Nurfauziah Ajeng Pramesti Amida S Sarbini Amini, Nadia Ushfuri Anbar Fatin, Mia Nisrina Ani Anggriani Ani Anggriani, Ani Aris Suhardiman Astira Kosmawati Budi, Hermawan Setya Budiana, Wempi Cici Valiani Desi Trisiani Destia Tresna Prima Dewi Mardiyah Diana Ulfah Eki Pratidina Fajarrini, Uvika Nurul Fatmawati, Fenti Fenti Fatmawati Fitriani Mardiana Garnadi Jafar, Garnadi Helen Fitri Novianti Herdiana, Geralda Bintang Ida Lisni Istiqomah, Aulia Nurfazri Jajang Japar Sodik Kania Fajarwati Khotimah, Nur Intan Husnul Madinatul Munawaroh Maharani, Ilmi Intan Manaf, Manaf Marita Kaniawati Mia Nisrina A Muslim, Dede Nur Aziz Nadia Ushfuri Amini Nazarul Mastura Nenden Ufiyani Noviyanti, Eva Pasha, ED. Yunisa Mega Purwaniati, Purwaniati R. Awaludin Nazal N Rahayu, Sri Mulyati Rahma Fatwia Ratu Fania Aprilyanti Roni, Asep Ruswanti, Seffi Saifurrohman, Arip Salsha Rosilopya Salwa Siti Balqis Sarbini, Amida S Saskia, Puti Bela Selifiana , Nita Selifiana, Nita Selvi Restiani Senjaya, Fathurahman Ari Sephia Indah Lutpiah Siti Balqis, Salwa Siti Rokmah Suherdin Suryanti, Wulan Maulani Susilawati, Elis Sutriyawan, Agung Valiani, Cici Vitniawati, Vina Wempi Budiana Yani Mulyani Yani Mulyani Zaelani, Diki Ziska, Rahma