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All Journal Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Jurnal Ilmu Kedokteran dan Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Bioscientia Medicina : Journal of Biomedicine and Translational Research Health Information : Jurnal Penelitian JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI Jurnal Manajemen dan Bisnis Baja (JUMANIS BAJA) Journal of Midwifery and Reproduction Jurnal Biosense Jurnal Abdimas Bina Bangsa Bioscientia Medicina : Journal of Biomedicine and Translational Research Journal of Baja Health Science Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat International Journal of Cell and Biomedical Science Journal of Health and Physical
Yuda Nabella Prameswari
Faculty Of Medicine And Health Sciences, Universitas Sultan Ageng Tirtayasa, Serang, Banten, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Hubungan Diabetes Melitus Tipe 2 dengan Penyakit Ginjal Kronis: Tinjauan Literatur: The Relationship Between Type 2 Diabetes Mellitus and Chronic Kidney Disease: A Literature Review Salsabila, Nuzulia Hikmah; Adhayati, Baety; Selfie, Selfie; Harahap, Alfuu Nur; Sitanggang, Ervina Julien; Prameswari, Yuda Nabella
Journal of Health and Physical Vol. 2 No. 1 (2026): April
Publisher : BALE LITERASI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/jhp.v2i1.2703

Abstract

Type 2 diabetes mellitus is a major global health problem and one of the leading causes of chronic kidney disease. Chronic hyperglycemia in diabetes plays a crucial role in the development of kidney damage, which may progress to end-stage renal disease if not properly managed. This review aims to explore the relationship between type 2 diabetes mellitus and chronic kidney disease, focusing on underlying pathophysiological mechanisms and clinical implications. A narrative review approach was conducted using literature from PubMed, ScienceDirect, and Google Scholar published between 2016 and 2026. The findings indicate that persistent hyperglycemia contributes to kidney damage through multiple interconnected mechanisms, including oxidative stress, inflammation, and fibrosis. These processes lead to structural and functional alterations in the kidney, such as glomerular dysfunction, declining glomerular filtration rate, and accumulation of metabolic waste products. Furthermore, the coexistence of diabetes and chronic kidney disease is associated with a higher risk of systemic complications, particularly cardiovascular disease, anemia, and metabolic disturbances, which significantly impact patient outcomes. Overall, type 2 diabetes mellitus and chronic kidney disease have a strong and complex relationship. Effective glycemic control, early detection, and comprehensive monitoring of kidney function are essential strategies to prevent disease progression and reduce the burden of complications, highlighting the importance of integrated management in patients with diabetes.
CRYPTOSPORIDIOSIS: EPIDEMIOLOGI, PATOGENESIS, MANIFESTASI KLINIS, DIAGNOSIS, DAN PENATALAKSANAAN: TINJAUAN LITERATUR Irawati, Nur Bebi Ulfah; Hermawati, Luluk; Nasution, Silvia Fitrina; Damayanti, Putri; Prameswari, Yuda Nabella; Zulfa, Hilizza Awalina
JURNAL BIOSENSE Vol 9 No 2 (2026): Edisi April 2026
Publisher : Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/biosense.v9i2.7673

Abstract

Cryptosporidiosis is a parasitic infection caused by protozoa of the Cryptosporidium genus that infect humans and animals worldwide. The disease remains a significant public health concern, particularly in regions with limited access to clean water and adequate sanitation. This study aimed to review recent scientific evidence regarding the epidemiology, pathogenesis, clinical manifestations, diagnosis, and management of cryptosporidiosis. A literature review method was employed by analyzing scientific articles published between 2015 and 2025 retrieved from databases including PubMed, Scopus and Google Scholar. Relevant studies were selected based on predefined inclusion criteria and analyzed narratively. The review indicates that Cryptosporidium hominis and Cryptosporidium parvum are the most common species causing human infection and account for the majority of cases worldwide. Transmission primarily occurs through the fecal–oral route via contaminated water or food, as well as direct contact with infected hosts. Infection involves parasite attachment and invasion of intestinal epithelial cells, leading to mucosal damage, malabsorption, and diarrhea. Clinical manifestations vary depending on the host's immune status, ranging from mild self-limiting diarrhea in immunocompetent individuals to severe and chronic infection in immunocompromised patients. Diagnosis is commonly established through microscopic detection of oocysts, antigen-based assays, and molecular methods such as polymerase chain reaction (PCR). Current management mainly focuses on supportive therapy, while nitazoxanide remains the only antiparasitic drug approved by the FDA for the treatment of cryptosporidiosis. Therefore, improvements in sanitation, development of diagnostic methods, and effective prevention strategies are essential to reduce the global burden of cryptosporidiosis.
Co-Authors Adhayati, Baety Aqila, Yasmin Nur Atmaja, Sukarta Damayanti , Putri Damayanti, Putri Dewi Friska Dewi Sukmawati Dewi, Adinda Puspita Dewi, Lola Febriana Dwi Anita Suryandari Ekawati Rini Wulansari Furqoni , Abdul Hadi Gayatri, Alya Indah Harahap, Alfuu Nur Hilizza Awalina Zulfa Ichwan Delfecio Imelda Rosalyn Sianipar Irawati, Nur Bebi Ulfah Linardita Ferial, Linardita Luluk Hermawati Luluk Yunaini Mirza Abdi Khairusy Nasution, Silvia Fitrina Neshya Ruriana Putri, Neshya Ruriana Novita Armelia Ramadhani Nugroho, Muhammad Rachman Putra, Alfian Prayana Ardie Rachmat, Omat Ria Kodariah Rossa Amelia, Rossa Rukman Abdullah Salsabila, Nuzulia Hikmah Selfie, Selfie Sitanggang, Ervina Julien Siti Darifah Utami, Louisa Ivana Zulfa, Hilizza Awalina