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All Journal Jurnal Kedokteran Brawijaya Mutiara Medika: Jurnal Kedokteran dan Kesehatan Jurnal Berkala Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat An-Nadaa: Jurnal Kesehatan Masyarakat Science Midwifery Community Empowerment JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Makara Journal of Science Homeostasis: Jurnal Mahasiswa Pendidikan Dokter Grimsa Journal of Science Engineering and Technology Holistik Jurnal Kesehatan
Roselina Panghiyangani
FK UNLAM
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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The Effect of Anti-Tuberculosis Drugs (ATT) Routine on Blood Profiles and Nutritional Status of Children at Ulin Hospital, Banjarmasin Khairiyadi, Khairiyadi; Sitompul, Putriana Br.; Putra, Nataniel Hadi; Panghiyangani, Roselina
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.5

Abstract

Tuberculosis (TB) is an infectious disease caused by the rod-shaped bacterium Mycobacterium tuberculosis (M. TB). TB primarily affects the lung parenchyma (pulmonary TB), but the bacterium can also infect other organs, leading to extrapulmonary TB. Anti-Tuberculosis Drugs (ATT) are a crucial component of TB treatment. However, the use of ATT is associated with side effects, the most common being anaemia and thrombocytopenia. This study aims to determine the effect of ATT on routine blood profiles and the nutritional status of pediatric patients with pulmonary TB and glandular TB at Ulin Regional Hospital, Banjarmasin. This analytical observational study employed a cross-sectional design. A total of 52 pediatric patients with pulmonary TB and glandular TB at Ulin Regional Hospital, Banjarmasin, were selected using a non-probability total sampling approach. The Wilcoxon test revealed a significant effect of ATT therapy on nutritional status, as indicated by a p-value of 0.000. ATT therapy results in changes in routine blood profiles and significant improvements in the nutritional status of pediatric patients with pulmonary TB and glandular TB. The significant changes in the routine blood profile are haemoglobin level and monocytes level which increased after ATT therapy. The average leukocytes, neutrophils, lymphocytes and Erythrocyte Sedimentation Rate (ESR) level decreased significantly after ATT therapy, while Platelet counts remained unchanged.
Co-Authors Adi Nugroho Ahmad Husairi Al-fath, Muhammad Fauzan Amalia, Aysca Fakhira Budiarman, Andi Azizah Maulidia Budinurdjaja, Pribakti Budiwinata, Winardi Darwis, Yulizar Dewi Indah Noviana Pratiwi, Dewi Indah Noviana Dewiarianti, Dewi Dian Ana Mutriqah Eka Yudha Rahman Eko Suhartono Fahdyanoor, Fahdyanoor Fatharoni, Gusti Dicky Fauzan Muttaqien Febriansyah, Muhammad Feodora, Anisha Nanda Hadi Putra, Nataniel Harapan Parlindungan Ringoringo, Harapan Parlindungan Himawan, Indra Widjaja Husaini Husaini Idhafi, Nasrul Istiana Istiana Iwan Aflanie Izaak Zoelkarnain Akbar, Izaak Zoelkarnain Khairiyadi Khairiyadi Lena Rosida Lenie Marlinae M. Bakhriansyah, M. Maghfirah, Yolanda Sajjida Marhaeni, Wulandewi Mawarni, Khairida Meitria Syahadatina Noor Muhammad Abdan Shadiqi Musafaah Musafaah Nasywa, Nabila Nelly Al Audhah Nia Kania Nila Nirmalasari, Nila Nizwar, Muhammad NURUL HIDAYAH Putra, Nataniel Hadi Rachman, M. Fathur Rahayu, Istuning Puji Rahmiati Rahmiati Raudhatul Jannah Rosihan Adhani, Rosihan Sari Dianita Purnama Sari, Ni Putu Sri Wulan Septerini, Ditha Detiana Silvia Kristanti Tri Febriana Siti Kaidah Sitompul, Putriana Br. Skripsiana, Nika Sterina Suhastinah, Suhastinah Sutapa, Hendra Syamsul Arifin Triawanti Triawanti Utami, Juliyatin Putri Uyun, Andi Quratul Vironika, Trisia Yulizar, Deddy Rasyidan ‘Azizah, Intan Nur