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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kedokteran Brawijaya Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Althea Medical Journal Jurnal Farmasi Klinik Indonesia INDONESIAN JOURNAL OF PHARMACY MNJ (Malang Neurology Journal) Universa Medicina Berkala Ilmiah Kedokteran Duta Wacana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmaseutik Jurnal Ilmiah Ilmu Kesehatan: Wawasan Kesehatan JFIOnline Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education JURNAL FARMASI GALENIKA YARSI Medical Journal Majalah Kedokteran Neurosains Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Kesehatan Cermin Dunia Kedokteran AKSONA Journal of Pain, Vertigo and Headache Pharmaceutical Sciences and Research (PSR) MEDICINUS Jurnal Farmasi Sains dan Praktis Berita Kedokteran Masyarakat Neurona Borneo Journal of Pharmacy Indonesian Journal of Pharmacology and Therapy Jurnal Penelitian Keperawatan Journal of Medicine and Health Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Rizaldy Pinzon
Fakultas Kedokteran Universitas Kristen Duta Wacana Yogyakarta
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : AKSONA

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Profile of Motoric and Non-Motoric Symptoms Using the Indonesian Version of the Wearing-Off Questionnaire-19 in Parkinson’s Patients Muktiarini, Bernadetha; Pinzon, Rizaldy Taslim; Prasetyo, Yacobus Christian
AKSONA Vol. 5 No. 2 (2025): JULY 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v5i2.60459

Abstract

Highlight: Tremors are the most common motor symptom in patients with Parkinson's disease. Abdominal discomfort is a prevalent non-motor symptom of Parkinson's disease. Comprehensive symptom management is essential for patients with Parkinson's disease.   ABSTRACT Introduction: Parkinson's disease is a neurodegenerative disorder characterized by motor and non-motor symptoms. The prolonged administration of levodopa in patients may induce the wearing-off phenomenon, where symptoms recur before the next dose. Studies on the symptom profile of Parkinson's disease, especially in wearing-off conditions, are crucial for further management. Objective: This study aimed to determine the motor and non-motor symptom profile of patients with Parkinson's disease. Methods: conducted. The Indonesian version of the Wearing-Off Questionnaire-19 (WOQ-19) was used to identify motor and non-motor symptoms. Data were collected from 30 Parkinson’s patients at Bethesda Yogyakarta Hospital from October to December 2023 using a purposive sampling technique. The sample size was calculated using OpenEpi V3.01. Results: The most prevalent motor symptom among patients with Parkinson's disease was tremor (100%), followed by bradykinesia (93.33%) and rigidity (86.67%). The most common non-motor symptoms reported were abdominal discomfort (56.67%) and body aches (50%). Conclusion:Patients have a variety of Parkinson's disease symptoms. Parkinson's patients most commonly experienced motor symptoms such as tremors, bradykinesia, and rigidity, along with non-motor symptoms like abdominal discomfort and body aches. The significant percentage of wearing-off seen in this study underscores its common occurrence and highlights the importance of early identification and management.  
Co-Authors Adnyana, Kadek Sinthia Grahita Agung Endro Nugroho Agung Wiwiek Indrayani Agustinus Rudolf Phyma, Agustinus Rudolf Al Jody, Abraham Al Jody, Abraham Alexxander Alexxander, Alexxander Alfi Yasmina Alfi Yasmina Amboro, Wisnu Anak Agung Gede Sugianthara Angela, Angela Ardiani, Birgitta Lisbethiara Bagaskara, Arya T Basuki, Mudjiani Bisay, Vallentino Ardine Prasetya Budi Harsana, Mary Rose Angelina Bustami, Mursyid Ciptasari, Debora Purwasista Daniel Mahendra Krisna, Daniel Mahendra Desyandri Desyandri Digdoyo, Ananda Dodik Tugasworo Erna Kristin Esdras Ardi Pramudita, Esdras Ardi Fedora, Gusti Ayu Jacinda Amanda Ferdy Firmansyah Firdaus Hafidz As Shidieq Fithrie, Aida Fransiska Theresia Meivy Babang, Fransiska Theresia Meivy Gelgel, Putu Clara Shinta Hakim, Manfaluthy Hardi Astuti Witasari Hariatmoko Hariatmoko, Hariatmoko Hidayat, Muh. Faris I Putu Eka Widyadharma Ida Safitri Laksanawati Ika Puspitasari Iwan Dwiprahasto Jarir At Thobari Jesisca, Jesisca Johan Budiman, Johan Kadex Reisya Sita Damayanti Kriswanto Widyo, Kriswanto Kushartanti, Bernadeta Margareta Wara Lailla Affianti Fauzi Laksmi Asanti, Laksmi Lestari, MMA Dewi Lucas Meliala Maharani, Anyelir Dewi Maharani, Regina Vika Marpaung, Refianda Olivia Febrianti Mitasari, Pradita S Mugiono, Iroen Muhammad Hasnawi Haddani Muktiarini, Bernadetha Muslimah Muslimah Nani Kurniani Nathanael, Hanshel Everad Novita Intan Arovah Nugraha, Boya Padma, Radha Govinda Pagan Pambudi Pandita, Felicia Dara Puspitaning Paramitha, Dessy Pratiwi, Woro Rukmi Priskila, Loury Priskila, Loury Purwaka, Barlaam Bagus Purwaka Purwandityo, Ayuningtyas Galuh Purwantiningsih, Purwantiningsih Putra, I Dewa Gde Rainey Chrisananta Ratih Puspita Febrinasari Rendra, Andreas K. Renita Sanyasi, Rosa De Lima Renita Sanyasi, Rosa De Lima Renita, Rosa De Lima Rosa De Lima Renita Sanyasi, Rosa De Lima Renita Setyawan, Irfanianta Arif Sinaga, Ruth Vanessa Gloria Sinulingga, Zenine Charolin Siti Nurhayati Sudharmadji Sugianto Sugianto s Sugianto Sugianto Susanto, Agnes Susi Susanti Sutejo, Mianti Nurrizky Thomas Eko Purwata Tri Murti Andayani Trijayanti, Christiana Vania Rau, Chiquita Putri Veronica, Vanessa Vidyatama, Veren Amoreta Widyantanti, Maria Atika Sukmana Wijaya, Vincent Ongko Wijono, Andre Dharmawan Wuysang, Audry Devisanty Y, Yudiyanta Yacobus Christian Prasetyo Yolanda Dyah Kartika Zalukhu, Marta Lisnawati