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All Journal Visual Communication Design Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Jurnal Akuakultura Universitas Teuku Umar SCRIPTA SCORE Scientific Medical Journal Respiratory Science Narra J International Journal of Health and Pharmaceutical (IJHP) The South East Asian Journal of Management The Journal of Society Medicine (JSOCMED) Jurnal Penyakit Dalam Indonesia Folia Medica Indonesiana
Andika Pradana
Institut Teknologi Bandung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Intervention Effect Between Smartphone and the Knowledge in Chronic Obstructive Pulmonary Disease Patients at Prof Chairuddin Panusunan Lubis General Hospital Tarigan, Amira Permatasari; Pradana, Andika; Rhinsilva, Ella; Ramadhani, Adini Arifah; Sihombing, Benny; Monica, Nanda Soraya; Vera, Yeni
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 2 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i2.14694

Abstract

Background: Health applications can assist in managing chronic patients such as Chronic Obstructive Pulmonary Disease (COPD). A smartphone application “Paru Sehat” is expected to help COPD patients increase their knowledge about the disease and its treatment. Objective: This study aims to examine the benefits of smartphone applications “Paru Sehat” on the level of knowledge of patients with the COPD about the disease and its treatment. Methods: A quasi-experimental studies were conducted in outpatient of stable COPD patients at Pulmonology and Respiratory Medicine Universitas Sumatera Utara Hospital. This research was conducted from March to June 2022. A questionnaire which elaborated question about COPD and its treatment were used to evaluate the level of knowledge of participants before and after 3 months of using smartphone application “Paru Sehat”. Results: From a sample of 38 COPD patients, the average knowledge level of COPD patients before using the “Paru Sehat” application as 5.125; after using the smartphone application, it was 8.5625. The hypothesis test shows that the value of p = 0.000, indicating an increase in the level of knowledge about COPD and its treatment. Out of 38 patients, all research subjects were male with the most age being 60 to 70 years old, having a history of heavy smoking and the highest level of severity of COPD 2. Conclusion: “Paru Sehat” application can influence the knowledge of COPD patients about their illness and treatment as well as the patient's independence in dealing with their illness. Keyword: COPD, level of patient knowledge, smarthphone application Latar Belakang: Aplikasi kesehatan dapat membantu dalam menangani pasien kronis seperti Penyakit Paru Obstruktif Kronik (PPOK). Aplikasi smartphone “Paru Sehat” diharapkan dapat membantu pasien PPOK meningkatkan pengetahuannya tentang penyakit dan pengobatannya. Tujuan: Penelitian ini bertujuan untuk menilai manfaat dari aplikasi smartphone “Paru Sehat” untuk tingkat pengetahuan pasien PPOK mengenai penyakit dan pengobatannya.  Metode: Penelitian quasi eksperimental dilakukan pada pasien PPOK stabil rawat jalan di Pulmonologi dan Kedokteran Respirasi Rumah Sakit Universitas Sumatera Utara. Penelitian ini dilakukan antara bulan Maret 2022 hingga Juni 2022. Kuesioner yang berisi pertanyaan tentang PPOK dan pengobatannya digunakan untuk mengevaluasi tingkat pengetahuan peserta sebelum dan sesudah 3 bulan menggunakan aplikasi smartphone “Paru Sehat”. Hasil: Dari sampel 38 pasien PPOK, rata-rata tingkat pengetahuan pasien PPOK sebelum menggunakan aplikasi smartphone “Paru Sehat” adalah 5,125; setelah menggunakan aplikasi smartphone menjadi 8.5625. Uji hipotesis menunjukkan nilai p = 0,000 yang menunjukkan adanya peningkatan tingkat pengetahuan tentang PPOK dan pengobatannya. Dari 38 pasien, seluruh subjek penelitian berjenis kelamin laki-laki dengan usia terbanyak yaitu 60 hingga 70 tahun, memiliki riwayat perokok berat dan tingkat keparahan PPOK 2 tertinggi (GOLD 2). Kesimpulan: Aplikasi “Paru Sehat” dapat mempengaruhi pengetahuan pasien PPOK tentang penyakitnya dan pengobatannya serta kemandirian pasien dalam menghadapi penyakitnya. Kata Kunci: Aplikasi smartphone, PPOK, tingkat pengetahuan pasien
Effects of Upper Arm and Breathing Exercise on Interleukin-6 in COVID-19 Patients Tarigan, Amira Permatasari; Listyoko, Aditya Sri; Pandia, Pandiaman; Pradana, Andika; Eyanoer, Putri Chairani; Sinaga, Sudirman Parningotan; Vera, Yeni; Firdaus, Ruby; Ramadhani, Adini Arifah
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.36-41

Abstract

Introduction: COVID-19 disease has become a comprehensive world issue and has been declared a significant threat to global health. Interleukin-6 (IL-6) is an important inflammatory marker and one of the triggers of the cytokine storm in COVID-19, where increased levels can be an independent predictor of COVID-19 mortality. This study aimed to observe the effect of upper arm and breathing exercises on IL-6 levels in severe COVID-19 patients. Methods: The study design was quasi-experimental, with blood tests conducted before and after the examination. A total of 20 patients with confirmed COVID-19 were involved, divided into intervention and control groups. Results: Blood tests to determine baseline IL-6 levels were performed in all patients. Patients from the intervention group were given upper arm and breathing exercises for ten days, twice a day, via video tutorials on mobile phones, while patients from the control group did not receive any exercises. Patients from the intervention group obtained mean pre- and post-exercise IL-6 levels of 42.38 ± 48.48 and 16.78 ± 18.29, respectively (p = 0.005). Conclusion: Upper arm and breathing exercises showed significant changes in IL-6 levels in severe COVID-19 patients.
A Rare Case of Completely Healed Pneumomediastinum Due to Asthma Exacerbation in A Young Male Patient Tarigan, Amira Permatasari; Pandia, Pandiaman; Pradana, Andika; Hutabarat, Eva Susanti Debora; Ramadhani, Adini Arifah
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.95

Abstract

Background: The term pneumomediastinum (PNM) refers to the presence of air within the mediastinal cavity. This illness is uncommon but can arise in adolescents with severe asthma attacks. In children aged 5 to 34, the incidence of pneumomediastinum after an acute asthma attack is 1 in 25,000. Men made up the majority of patients (76 percent of all cases). Pneumomediastinum can be diagnosed with the assistance of a chest CT scan. Case: A young man was diagnosed with pneumomediastinum due to an acute asthma attack in this case report. Symptoms of uncontrolled asthma include shortness of breath that worsens with wheezing, chest tightness, and a nonproductive cough. Since the age of 12, the patient in this instance has been receiving salbutamol inhalers. The physical examination revealed polyphonic lung respiration and subcutaneous crepitus in the neck, shoulders, and anterior chest. With adequate management of an asthma episode, pneumomediastinum recovers spontaneously, followed by recurrent symptomatic status, physical examination, and radiography examination. Discussion: Acute asthma exacerbations are one of the factors that can lead to spontaneous pneumomediastinum, in which mediastinal air can permeate the tissue and generate a pneumothorax, and if there is air in the subcutaneous area, it can lead to subcutaneous emphysema. Conclusion: Pneumomediastinum was a rare incidence, pulmonologists examining young adults with acute asthma exacerbations should evaluate for pneumomediastinum. In usual asthma therapy, a chest CT-scan is essential to screen for pneumomediastinum.
Pulmonary Function Recovery After Treatment in Drug Sensitive TB: What Factors Matter? Simbolon, Novery; Pandia, Pandiaman; Pradana, Andika; Anhar, Taufik
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.465

Abstract

Background: Indonesia ranks second globally in tuberculosis burden, and up to 50% of treated patients develop pulmonary dysfunction. Objectives: To identify clinical and radiographic factors influencing spirometric recovery after treatment in drug-sensitive pulmonary tuberculosis. Methods: Analytical observational study with cross-sectional design. Population comprised adults (>18 years) in Medan who completed standard drug-sensitive TB therapy within six months. Sixty participants were selected by consecutive sampling. Instruments included spirometry (Global Lung Function Initiative 2022 equations) and chest radiograph scoring. A structured questionnaire captured demographics, TB history, comorbidities, and smoking. Data analysis involved bivariate tests (chi-square, Kruskal–Wallis, Fisher’s exact) and multivariate logistic regression (enter method). Results: Advanced radiographic lesion extent was the only independent predictor of abnormal spirometry (Exp(B)=4.889; 95% CI 1.386–17.241; p=0.014). Other variables lost significance after adjustment. Conclusion: Initial lesion burden on chest radiograph strongly determines pulmonary function recovery post-treatment. Early stratification by lesion extent is recommended for targeted follow-up and rehabilitation
Incidence of Malnutrion Based On Body Mass Index And Subjective Global Assesment In Patients With Stable Chronic Obstructive Pulmonary Disease Dalimunthe, Muhammad Bayhaqi; Pradana, Andika; Tarigan, Amira Permatasari; Amelia, Rina
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.467

Abstract

Background: Malnutrition is a serious problem in patients with COPD, it interferes with normal skeletal muscle function, with reduced muscle mass and decreased respiratory muscle strength and endurance. The purpose of the study was to determine the incidence of malnutrition based on BMI and SGA in patients with stable chronic obstructive pulmonary disease at the Prof. Dr. Chairuddin P. Lubis Medan Teaching Hospital. Method: The research design is an observational analytic, from November 2023 to March 2024. The study population was COPD patients who sought treatment at the Pulmonary Polyclinic at RSCPL with a total sample using the consecutive sampling method of 91 people Assessment of BMI by measuring TB and BW of patients when they came and assessment of SGA with a questionnaire Data processing using SPSS using descriptive statistics by displaying the IMT and SGA frequency distribution tables. Result: The results of this study found that most patients were categorized as underweight, namely 28 patients (30.8%). The majority of SGA classification as underweight/moderate nutrition "SGA B", namely 50 patients or (54.9%). Conclusion: We found that the Subjective Global Assessment (SGA) questionnaire is very influential in detecting patients with COPD who are malnourished to reduce respiratory muscle decline, and relapse of exacerbations.
Bacterial Profiles and Antibiotic Resistance in Chronic Obstructive Pulmonary Disease Patients with Exacerbation and Type 2 Respiratory Failure at Adam Malik General Hospital Annisa, Lia Mutia; Syarani, Fajrinur; Pradana, Andika; Mutiara, Erna
Folia Medica Indonesiana Vol. 60, No. 3
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: 1. This study provides a comprehensive analysis of various factors such as age, sex, education, occupation, BMI, and comorbidities, and their relationship with bacterial infections in COPD patients experiencing exacerbation and type 2 respiratory failure. 2. While the COPD patients experiencing exacerbation did not exhibit resistance to linezolid and vancomycin, they demonstrated specific antibiotic resistance patterns characterized by high resistance rates to commonly used antibiotics such as meropenem and amikacin. 3. The findings enhance the understanding of the complex interplay of factors influencing infection patterns in this patient population. Abstract Chronic obstructive pulmonary disease (COPD) is a prevalent condition characterized by persistent respiratory symptoms and airflow limitation. Bacterial infections may trigger COPD exacerbations, leading to more severe symptoms as well as increased morbidity and mortality rates. This study aimed to investigate the bacterial profiles and antibiotic resistance in COPD patients who had experienced exacerbation and type 2 respiratory failure at Adam Malik Central General Hospital, Medan, Indonesia. This retrospective study utilized medical records spanning from January 1, 2020, to December 1, 2022. The sample included patients aged 40–90 years who had experienced COPD exacerbation and type 2 respiratory failure. The exclusion criteria were patients who had received antibiotic therapy within 48 hours before admission, were severely immunocompromised, and had severe malignancy. The analysis results were presented in the form of means, standard deviations, and frequency distributions. Additionally, an analysis of the relationship between the categorical variables was performed using the Chi-squared test (p<0.05). The study analyzed 25 subjects with an average age of 63.6 years, primarily consisting of men (84%). It was shown that severe exacerbations were prevalent (92%), accompanied by the presence of common comorbidities including pneumonia (52%), diabetes mellitus (32%), and other non-communicable diseases (44%). Bacterial growth was observed in 76% of the subjects, predominantly involving Gram-negative bacteria (89.4%). Klebsiella pneumoniae (26.3%) and Pseudomonas aeruginosa (21.1%) were the most frequently isolated species. The antibiotic resistance patterns indicated that meropenem and amikacin had the highest resistance rates (100%). Cefepime, ertapenem, and gentamicin exhibited notable resistance rates of 66.7%, 66.7%, and 75.0%, respectively. This study highlights the high prevalence of Gram-negative bacteria and significant antibiotic resistance in COPD patients who exhibit exacerbation and type 2 respiratory failure.
The Effectiveness Comparison of Salmeterol/Fluticasone Propionate and Formoterol Fumarate/Budesonide on Level of Asthma Control in Moderate Persistent Asthma Resti, Riska; Tarigan, Amira Permatasari; Pradana, Andika; Wahyuni, Arlinda Sari
Jurnal Respirologi Indonesia Vol 46 No 1 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v46i1.851

Abstract

Background: Asthma is a prevalent chronic respiratory disease, affecting approximately 1–18% of the population worldwide. Despite its high prevalence, a substantial proportion of patients have partially controlled asthma, and limited data on the level of asthma control remain a significant concern. This study aimed to compare the effectiveness of salmeterol/fluticasone propionate and formoterol fumarate/budesonide in achieving asthma control levels according to the ACQ-GINA criteria. Methods: A retrospective cohort study was conducted using 61 medical records from January 2017 to December 2019. Patients with moderate persistent asthma received either salmeterol/fluticasone propionate or formoterol fumarate/budesonide for at least three months. Statistical analysis was performed using Fisher’s exact test. Results: A total of 61 patients were included. Most patients had partially controlled asthma (70.5%), followed by well-controlled (19.7%) and uncontrolled asthma (9.8%). No statistically significant difference in asthma control was observed between the two treatment groups (P=0.057). Conclusion: Within the limitations of this retrospective cohort study, no statistically significant difference in asthma control was observed between salmeterol/fluticasone propionate and formoterol fumarate/budesonide.
Co-Authors Abdullah, Muntasir Adida, Fiony Amin, Mona N. Amin, Mustafa M. Anhar, Taufik Annisa, Lia Mutia Aritonang, Minarni ES. Dalimunthe, Muhammad Bayhaqi Dalimunthe, Naomi Niari Damanik, Rizki amaliah Dangana, Amos Darmawan, Nengah Deneuve, Olivia Monica Erna Mutiara Eyanoer, Putri C. Febrina, Citra Dina Firdaus, Ruby Hutabarat, Eva Susanti Debora Imam Salehudin Iman Sudjudi Lingga, Elfia Damaiyanti Br Listyoko, Aditya S. Listyoko, Aditya Sri Mahendra, Mahendra Maryaningsih, Maryaningsih Monica, Nanda S. Monica, Nanda Soraya Nasution, Syafiah Amalina Osareniro, Osakue E. Pandia, Pandiaman Panjaitan, Samuel Hendryk Putra, M Yusuf Adira Putri Chairani Eyanoer, Putri Chairani Ramadhani, Adini Arifah Resti, Riska Rhinsilva, Ella Rina Amelia Rusda, Muhammad Sari, Dina K. Sebayang, Risa RB. Sihombing, Benny Simbolon, Novery Sinaga, Bintang YM. Sinaga, Sudirman P. Sinaga, Sudirman Parningotan Soeroso, Noni N. Supriatmo Supriatmo, Supriatmo Syarani, Fajrinur Tarigan, Amira P. Tarigan, Amira Permatasari Taufik Ashar Triwahyudi, Bibit Vera, Yeni Wahyuni, Arlinda S. Wahyuni, Arlinda Sari Wijanarko, Wahyu Wiwien H. Wiyono Yusran Ibrahim Zulkarnain Zulkarnain