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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia The Journal of Experimental Life Sciences (JELS) Media Penelitian dan Pengembangan Kesehatan Biogenesis: Jurnal Ilmiah Biologi Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Journal of Innovation and Applied Technology Research Journal of Life Science Natural B REKAYASA International Journal of Applied Biology JURNAL ENGGANO Jurnal Sumberdaya Akuatik Indopasifik Jurnal Penelitian Pendidikan IPA (JPPIPA) JPM (Jurnal Pemberdayaan Masyarakat) JURNAL ILMIAH PETERNAKAN TERPADU Indonesia Journal of Halal Samakia: Jurnal Ilmu Perikanan Jurnal Kelautan Nasional Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Journal of Aquaculture and Fish Health Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering (AFSSAAE) Jurnal Abdi Insani Jurnal Perikanan Pantura Berkala Penelitian Hayati Journal of Agri-Food Science and Technology (JAFoST) JAPI: Jurnal Akses Pengabdian Indonesia Journal of Fisheries & Marine
Asep Awaludin Prihanto
Brawijaya University
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Journal : Natural B

 1 
Antimalarial Activity (Plasmodium falciparum 3D7) from Sea Sponge Acanthella sp. faidzil Ikram; Asep Awaludin Prihanto; Choiriyatun Hanifah; Muhammad Iqbal
Natural B, Journal of Health and Environmental Sciences Vol 1, No 3 (2012)
Publisher : Natural B, Journal of Health and Environmental Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (28.564 KB) | DOI: 10.21776/ub.natural-b.2012.001.03.1

Abstract

The objective of the research was to get the bioactive candidates from marine sponge Acanthella sp. for anti multi resistant malaria. The first Research was conducted with isolating the active compounds of Acanthella sp. In vitro antimalarial test against Plasmodium falciparum 3D7 was done with several concentrations with positive control using chloroquinon the quantification of the Scizon inhibition was performed with blood staining. Afterward, the infected erythrocytes per 1000 erythrocytes was calculated. IC50 was assayed with probit analysis. The result indicated that all four active fractions showed inhibition on growth of P. Falciparum with different value on IC50. The best fraction is confirmed by fraction B with IC50 of 0.013 ppm.
Co-Authors Abdul Aziz Jaziri Abu Bakar Sambah Abu Bakar Sambah Aditia Gustiana Gunawan Affan Gaffar Agus Susilo Akhiroh, Puji Alifatul Fatchiyah Andi Kurniawan Andi Kurniawan Angga Wira Perdana Anies Chamidah Anies Chamidah Anif Fatwa Chawa Anisa Millah Taqiyyah Anisa Millah Taqiyyah Ardiansyah Kurniawan Beauty Suestining Diyah Dewanti Choiriyatun Hanifah Dedes Amertaningtyas Djamaludin, Heder Dodyk Pranowo Dwi Febrianti Eddy Suprayitno Euis Asriani Euis Asriani Euis Asriani faidzil Ikram Farida Isroani Farikh Assafri Firman Jaya Gandhatyasri Rohmah, Wendra Gilang Drajat Maulana Guntur Guntur Hanan Dwi Laksono Timur Happy Nursyam Hardoko Hardoko Hardoko Hardoko Hariati, Anik Martinah Herly Evanuarini Hidayatun Muyasharoh Hidayatun Muyasyaroh Hidayatun Muyasyaroh Hidayatun Muyasyaroh Jauharotul Afifah Karimah Karimah Kartika D. Aninta Kartikaningsih, Hartati Ken Audia Pradarameswari Ken Audia Pradarameswari Ken Audia Pradarameswari Khotibul Umam Al Awwaly Linggar Rucitra, Andan M. Aris Munandar Maftuch Maftuch Marlinda Elvina Susanti Masyithoh, Dewi Melianti, Rika Gian Miftakhul Cahyati MOHAMAD FADJAR Mohammad Fadjar Morita Ikasari, Dhita Muhamad Firdaus Muhammad Firdaus Muyasyaroh, Hidayatun Nada Itorul Umam Nurjannah Nurjannah Premy Puspitawati Rahayu Putra, Prily Lovian Rahmi Nurdiani Randy Fahrudin Ardiansyah Ria Dewi Andriani Rina Rifqie Mariana Riska Septifani Soffi Trisnaningrum Suci Puspita Sari Suci Puspita Sari Suci Puspita Sari Suci Puspitasari Sukoso Sukoso Suprayogi Suprayogi Tambunan, Jenny Ernawati Titis Sari Kusuma Tri Widayanti, Vindhya Umam, Nada Itorul Wenny Bekti Sunarharum Yanuhar, Uun Yenny Risjani YOGA DWI JATMIKO Yoga Dwi Jatmiko Yunita Eka Puspitasari