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All Journal Medical Journal of Indonesia Indonesian Journal of Cancer Indonesian Journal of Rheumatology World Nutrition Journal Indonesian Journal of Cancer The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Ikhwan Rinaldi
Divisi Hematologi Onkologi Medik, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Indonesia, Rumah Sakit Dr. Cipto Mangunkusumo
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : World Nutrition Journal

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Correlation between Zinc Intake and Zinc Serum Levels with C-reactive Protein Level in Head and Neck Cancer Patients Muningtya Philiyanisa Alam; Diana Sunardi; Ikhwan Rinaldi
World Nutrition Journal Vol. 2 No. 2 (2019)
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V02.i2.0003

Abstract

The inflammatory process of head and neck cancer leads to an increase the proinflammatory cytokines and the synthesis of c-reactive protein (CRP), which then causes metabolic alteration and anorexia in the patients. Zinc is one of  nutrient that has an important role in suppressing inflammation, but it is reported that about 65% of head and neck cancer patients have zinc deficiency. The aim of this cross sectional study is to determine the correlation between zinc intake and serum zinc levels with CRP level as an effort in reducing inflammation process in head and neck cancer patients. Subjects were collected by consecutive sampling in the Oncology Polyclinic Rumah Sakit Kanker Dharmais, from 49 subjects 67,3% were men, most subjects were in the age range between 46–65 years. The highest frequency (65,3%) is nasopharyngeal cancer and 69,4% are already in stage IV. All subjects (100%) in this study have a zinc intake below the recommended dietary allowance (RDA) in Indonesia. The mean serum zinc level of the subjects was 9.83±2.62 μmol/L. Most subjects have elevated CRP levels. There was a weak negative correlation between zinc concentration and CRP levels of subjects (r =-0.292, p =0.042), but there was no correlation between zinc intake and CRP levels of subjects (r =-0.25).
Co-Authors Achmad Fauzi Achmad Fauzy, Achmad Adhiatma, Kresna Adityo Susilo, Adityo Adna, Rury Maharani Afifah Is Agnes Stephanie Harahap Agus Sudiro Waspodo Aida Lydia Andhika Rachman Andri Sanityoso Sulaiman Angraeni, Sri Anna Rozaliyani Ari Fahrial Syam Arif Harryanto Reksodiputro Arif Harryanto Reksodiputro, Arif Harryanto Arini Setiawati Arry Haryanto Reksodiputro Artati Murwaningrum, Artati Bambang Setyohadi Bambang Setyohadi Birry Karim C Rinaldi A Lesmana Ceva W. Pitoyo Cleopas Martin Rumende Cleopas Martin Rumende Cosphiadi Irawan Czeresna Heriawan Soejono Dadang Makmun Dewi Mira Ratih Diana Sunardi Djatikusumo, Ari Dono Antono Dyah Purnamasari E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edy Rizal Wahyudi Em Yunir Em Yunir, Em Endang Susalit Endy Novianto Endy Novianto, Endy Evy Yunihastuti Findy Prasetyawati Findy Prasetyawati, Findy Firsyada, Fajar Gurmeet Singh Hasan Maulahela Henry Ratno Diono Silalahi Henry Ratno Diono Silalahi, Henry Ratno Diono HILMAN TADJOEDIN, HILMAN Ibrahim, Febiansyah Ika Prasetya Wijaya Ilyas, Mohammad Imelda Maria Loho, Imelda Maria Iris Rengganis Irsan Hasan Jerry Eddya Putra Boer Juferdy Kurniawan Kaka Renaldi Karmel L Tambunan, Karmel L Kuntjoro Harimurti Kusumaningrum, Profitasari Kusumowidagdo, Gladys Lestari, Regina Lianda Siregar Lisnawati Rachmadi Lugyanti Sukrisman Lukman Edwar Lutfiah, Evah Marbun, Maruhum Bonar Hasiholan Mardianto, Umar Margaluta, Ariansah Martin, Cleopas Maruhum B.H. Marbun Miranda, Monik Ediana Mohammad, Nurhidayat Muhadi Muhadi Muhadi Muhadi, Muhadi MUHAMMAD SYAFIQ Muningtya Philiyanisa Alam Murdani Abdullah Murdani Abdullah Mustopa, Inna Intani Nabil Mubtadi Falah Nabil Mubtadi Falah, Nabil Mubtadi Nikko Darnindro Noto Dwimartutie Nunuk Mardiana, Nunuk Pratiwi, Amalia Nur Pringgodigdo Nugroho, Pringgodigdo Purwita Wijaya Laksmi Rahmat Cahyanur Rahmat Cahyanur Rasco Sandy Sihombing Rasco Sandy Sihombing, Rasco Sandy Ratih, Dewi Mira Regina Lestari Reinaldo Alexander Reksodiputro, Arry H. Reza Yogaswara Rino Alvani Gani Robert Sinto Rudi Putranto Rudi Putranto Rudy Hidayat Sabrina Munggarani Yusuf Sarasawati, Meilania Saskia Aziza Nursyirwan, Saskia Aziza Sepmeitutu, Iwandheny Shufrie Effendi, Shufrie Sukamto Koesnoe Sulaiman, Andri Andri T. Djumhana Atmakusuma, T. Djumhana Tanadi, Caroline Tengku Riza Zarzani N Tri Juli Edi Tarigan Triyanta Yuli Pramana Virnanda Amu, Ivan Wahyu Sulistiadi Wardhani, Ariani Intan Wardoyo, Elizabeth Y Wardoyo, Elizabeth Yasmine Yogaswara, Reza Yudantha, Anggun R.