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Anti Bacterial Activity Test of Ethanol Extract of Papaya Leaves (Carica papaya L) on the Growth of Staphylococcus epedermidis Jon Kenedy Marpaung; Suryani, Monica; Ivan Elisabeth Purba
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.468 KB)

Abstract

Papaya is a tropical plant from the Caricaceae family, botanically defined as Carica papaya L. Traditional use of papaya leaves is to prevent bleeding in wounds and to treat wounds, lower high blood pressure, treat dengue fever, eliminate acne and smooth the skin and digestive disorders. Staphylococcus epidermidis is a Gram-positive bacterium, immobile, non-sporing, in solid culture media in the form of cocci in irregular groups, the arrangement is similar to grapes, prominent, shiny, does not produce pigment, white in color. Staphylococcus epidermidis bacteria can cause swelling (abscess) diseases such as acne, skin infections, urinary tract infections and swelling of the kidneys. This study was conducted with the aim of knowing the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya L) with concentrations of 5%, 10%, 15%, and 20% against the growth of Staphylococcus epidermidis bacteria. This research method used an experimental method, namely to determine the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya L) against the growth of Staphylococus epidermidis bacteria. This research used 96% ethanol as solvent. The test was carried out through several stages including material collection, preparation of simplicia, manufacture of ethanol extract from papaya leaves by maceration and testing of antibacterial activity against Staphylococus epidermidis bacteria. Based on the results of the phytochemical screening test of the thick extract, papaya leaves contain a class of alkaloid compounds, flavonoids, saponins, steroids/triterpenoids and tannins. The results of the antibacterial activity test of thick papaya leaf extract against Staphylococus epidermidis bacteria had an average inhibitory activity at concentrations of 5% (7.33 mm), 10% (8.44 mm), 15% (9.44 mm) and 20 % (10.3mm). As a comparison, Cloramfenocol 30 g was used to produce an inhibitory power of 32.1 mm and the best results obtained were at a concentration of 20% which had an inhibitory power of 10.3 mm.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEPUASAN PASIEN PADA PELAYANAN KESEHATAN DI UPT PUSKESMAS SUKARAMAI KOTA MEDAN Alyakin Dakhi, Rahmat; Mido Ester J. Sitorus; Netti Etalia Brahmana; Ivan Elisabeth Purba; Lyenta Simanullang; Toni Wandra; Masdalina Pane
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 7 No. 1 (2025): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/tekesnos.v7i1.6273

Abstract

Background: Patient satisfaction is heavily influenced by the quality of services provided by healthcare centers (Puskesmas). The World Health Organization (WHO) states that good healthcare services are those that are effective, safe, and of high quality for those in need. Purpose: This study aims to identify the factors associated with patient satisfaction regarding healthcare services at Puskesmas Sukaramai. Method: The research is a quantitatfve study with a cross-sectional design, conducted in the operational area of Puskesmas Sukaramai, Medau City, from Maret-Juni 2025. The study population includes all patients visiting the Puskesmas, totaling 619 per month. The sample size was determined using the Lemeslow formula, with a sample af 149 respondents selected through accidental sampling. Primary data were collected dfrectly through questionnaires distributed ta patients visiting Puskesmas Sukaramai. Data analysis was carried out using both univariate and bivariate methods, With hypothesis testing conducted using the Chi-square statistical test. Results: The study results indicate significant relationships between physical evidence (tangible) and patient satisfaction (p=0.000), reliability and patient satisfaction (p=0.000), responsiveness and patient satisfaction (p=0.000), assurance and patfent satisfaction (p=0.000), and empathy and patient satisfaction (p=0. 002 < 0.05. Disscusion and Conclusion: it is recommended that healthcare workers focus on improving service cleanliness, friendliness, and efficiency at Puskesmas Sukaramai to enhance patfent satisfaction.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN PIRDOT (Saurauia vulcani korth) TERHADAP KADAR ERITROSIT TIKUS JANTAN (Rattus novergicus) YANG DI PAPARI TUAK NIAS Manurung, Kesaktian; Janno Sinaga; Ivan Elisabeth Purba; Mido Ester J. Sitorus; Farah Lutfia
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 7 No. 2 (2025): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/tekesnos.v7i2.6922

Abstract

Latar belakang: Eritrosit merupakan sel darah merah yang berperan penting dalam transportasi oksigen, pengangkutan karbon dioksida, serta menjaga keseimbangan asam-basa tubuh. Daun pirdot (Saurauia vulcani Korth.) diketahui mengandung senyawa metabolit sekunder seperti alkaloid, flavonoid, tanin, dan saponin. Tujuan: Senyawa ini berpotensi mendukung proses eritropoiesis melalui stimulasi sumsum tulang dan aktivitas antioksidan yang melindungi sel darah merah dari kerusakan. Metode: Penelitian ini menggunakan metode eksperimental dengan tahap penyiapan sampel, pembuatan ekstrak etanol daun pirdot melalui maserasi, karakterisasi simplisia, skrining fitokimia, serta uji efektivitas terhadap eritrosit tikus jantan (Rattus norvegicus) yang dipapari tuak Nias 29% alkohol. Hasil karakterisasi menunjukkan bahwa simplisia daun pirdot memenuhi standar FHI edisi II 2022 dan ekstrak etanol positif mengandung alkaloid, flavonoid, tanin, dan saponin. Uji efektivitas menunjukkan rata-rata kadar eritrosit: K0 = 5,00×10¹²/L, P1 = 1,65×10¹²/L, P2 = 4,82×10¹²/L, P3 = 4,17×10¹²/L, P4 = 4,19×10¹²/L, dan P5 = 5,45×10¹²/L. Kelompok P1 mengalami penurunan eritrosit paling signifikan, sedangkan P5 menunjukkan peningkatan tertinggi. Analisis ANOVA (p<0,05) dan uji Tukey HSD membuktikan bahwa ekstrak daun pirdot secara signifikan meningkatkan kadar eritrosit dibanding kelompok yang hanya menerima paparan alkohol. Kesimpulan: Disimpulkan bahwa ekstrak etanol daun pirdot memiliki potensi sebagai agen protektif terhadap penurunan eritrosit akibat paparan alkohol, sekaligus mendukung pemulihan fungsi hematopoietik.
Application of K-Means and Decision Tree for Disease Prediction Using Data Mining Approach Riah Ukur Ginting; Fernando H Sinaga; Rianto Sitanggang; Ivan Elisabeth Purba; Aprima A Matondang
ZETROEM Vol 8 No 1 (2026): ZETROEM
Publisher : Prodi Teknik Elektro Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/ztr.v8i1.7634

Abstract

This study aims to analyze the distribution patterns of patient diseases using a data mining approach at UPTD Puskesmas Pakkat. The dataset consists of secondary data from 4,633 patients collected between January 2022 and December 2023, obtained from digital medical records, with variables including age, gender, and 22 disease diagnosis categories. The K-Means Clustering method was employed to identify disease grouping patterns based on patient characteristics. The optimal number of clusters was determined using the Silhouette Score, with the best value of 0.5556 at K=6. Cluster quality was further evaluated using the Davies-Bouldin Index (DBI) with a value of 0.6722, indicating good cluster separation. To support the classification process, the Decision Tree algorithm was applied to predict cluster membership for new patient data. Model evaluation was conducted using a train-test split scheme and k-fold cross-validation to enhance reliability and minimize the risk of overfitting. The results indicate distinct disease patterns across age groups, where infectious diseases such as acute respiratory infections (ARI) and diarrhea dominate in children, while non-communicable diseases such as hypertension and diabetes are more prevalent among adults and the elderly. This study contributes by integrating clustering and classification methods and provides data-driven epidemiological insights that can support decision-making in primary healthcare services.