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The Effect of Health Education on Knowledge of Health Reproductive of Junior High School Students. Nadia Purnama Dewi; Prima Della Fegita; Dessy Abdullah
Journal on Education Vol 5 No 4 (2023): Journal on Education: Volume 5 Nomor 4 Mei-Agustus 2023
Publisher : Departement of Mathematics Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joe.v5i4.2782

Abstract

When they reach puberty, adolescents need to learn about reproductive health. Giving adolescents health education to prevent issues with their reproductive health is one method to boost their awareness of reproductive health. The purpose of this study is to determine how health education has affected students' knowledge of reproductive health. 24 persons were gathered using the convenience sample method. Pre-experimental design with one-group pretest-post-test design is the technique employed. A questionnaire was employed as a research tool during the data collection process. The Wilcoxon test is the method of data analysis that is utilized. The findings revealed that students' knowledge had an average value of 82 percent before receiving health education, and an average value of 84 percent after receiving health education. There was no significant difference in the knowledge of adolescents before and after receiving health education, according to the findings of the hypothesis test, which had an alpha error rate of 0.05. It might be said that health education has little impact on the degree of knowledge held by teenagers.
ANALYSIS OF THE RELATIONSHIP BETWEEN GASTROESOPHAGEAL REFLUX DISEASE (GERD) AND PATIENTS’ SMOKING PATTERNS AND COFFEE CONSUMPTION Gangga Mahatma; Vina Tri Septiana; Irwan Triansyah; Dessy Abdullah; Ade Teti Vani
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2023): Volume 4 Nomor 2 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of this study was to investigate the association between coffee drinking, smoking, and the prevalence of gastroesophageal reflux disease (GERD) in college students. This study is an observational analytic cross-sectional study that employs a quantitative methodology. 200 participants were chosen at random from a basic random sample in order to conduct this study. In this research, the findings of the chi-square examination conducted to determine the correlation between coffee intake and the occurrence of GERD revealed a noteworthy association between the two variables. Similarly, the results of the chi-square test conducted to establish the link between smoking practices and the incidence of GERD demonstrated a significant association between the two. Consequently, it can be inferred that there is a significant correlation between coffee consumption, smoking habits, and the incidence of GERD in college students.
THE APPLICATION OF ANATOMICAL THERAPEUTIC CHEMICAL METHOD TO EVALUATE THE USE OF ANTI-HYPERTENSION DRUGS IN INPATITION INSTALLATIONS OF REGIONAL GENERAL HOSPITALS Dessy Abdullah; Riki Nova; Gangga Mahatma; Rika Amran; Bun Yurizali
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2023): Volume 4 Nomor 4 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i4.20005

Abstract

Tujuan dari penelitian ini adalah untuk mengetahui jenis dan proporsi obat antihipertensi yang diminum oleh pasien hipertensi yang dirawat di rumah sakit. Metodologi penelitian deskriptif cross-sectional digunakan dalam penelitian ini. Semua pasien hipertensi yang dirawat di rumah sakit menjadi populasi penelitian. Purposive sampling dengan menggunakan sistematik random sampling digunakan dalam penelitian ini untuk mendapatkan 100 sampel. Penelitian retrospektif, atau penelitian berdasarkan rekam medis pasien, digunakan untuk memperoleh data untuk penelitian ini. Analisis univariat dan pendekatan DDD/ATC akan digunakan untuk menilai analisis data yang dilakukan dengan menggunakan aplikasi Microsoft Excel. Ada beberapa kesimpulan yang dapat diambil dari temuan penelitian ini: Berdasarkan usia dan jenis kelamin, mayoritas pasien hipertensi adalah perempuan. Stroke iskemik merupakan penyakit penyerta yang paling banyak dialami oleh penderita hipertensi, sesuai dengan jenis penyakit penyertanya. Kebanyakan pasien hipertensi mempunyai tekanan darah sistolik kurang dari 160 mmHg dan seringkali mempunyai tekanan darah diastolik kurang dari 100 mmHg. Amlodipine terbukti menjadi obat antihipertensi yang paling sering digunakan oleh pasien hipertensi, diukur dari jumlah penggunaan. Amlodipine, ramipril, captopril, dan irbesartan adalah obat antihipertensi yang termasuk dalam sebagian besar bagian DU, menurut profil DU mayoritas. Obat antihipertensi yang digunakan sesuai dengan formularium rumah sakit.
Patofisiologi Biomedik Depresi: Tinjauan Komprehensif terhadap Mekanisme Neurobiologis Mutiara Anissa; Dessy Abdullah
Scientific Journal Vol. 4 No. 3 (2025): SCIENA Volume IV No 3, May 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v4i3.217

Abstract

Depresi merupakan salah satu gangguan psikiatri yang paling sering dijumpai di populasi umum dan berkontribusi signifikan terhadap morbiditas serta disabilitas global. Dari perspektif biomedik, depresi bukan hanya kondisi psikologis, melainkan gangguan yang ditandai oleh perubahan kompleks pada sistem saraf pusat, neuroendokrin, dan imun. Tulisan ini bertujuan untuk memberikan tinjauan sistematis dan mendalam mengenai mekanisme biomedik yang melandasi gangguan depresi, termasuk disfungsi neurotransmiter, hiperaktivasi sumbu hipotalamus-hipofisis-adrenal (HPA), neuroinflamasi, gangguan neuroplastisitas, dan implikasi genetik-epigenetik. Pemahaman yang mendalam terhadap aspek biomedik ini menjadi dasar penting dalam pengembangan pendekatan terapi yang lebih tepat sasaran dan efektif.
IMPLEMENTING RAPID NEEDS ASSESSMENT TO IMPROVE HUMANITARIAN AID DISTRIBUTION FOLLOWING THE 2025 FLASH FLOOD IN PADANG CITY, INDONESIA: A COMMUNITY SERVICE EXPERIENCE Ade Teti Vani; Irwan Triansyah; Nadia Purnama Dewi; Dessy Abdullah; Yuri Haiga; Debie Anggraini; Prima Adelin; Dita Hasni
Nusantara Hasana Journal Vol. 6 No. 1 (2026): Nusantara Hasana Journal, June 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i1.2254

Abstract

Humanitarian aid is one of the most critical components of disaster response. However, relief distribution during the emergency phase is frequently driven by donor availability rather than by the actual needs of affected communities. Consequently, while essential supplies such as food and drinking water are often adequately provided, personal necessities that directly influence dignity, hygiene, and daily living remain insufficient. Rapid Needs Assessment (RNA) is recommended as a systematic approach to identify priority needs and improve the effectiveness of humanitarian interventions. This community service program aimed to implement a Rapid Needs Assessment before humanitarian aid distribution for victims of the 2025 flash flood in Padang City, Indonesia. The program was conducted during the emergency response period following the flash flood on 26 November 2025. A collaborative team of university lecturers and members of the Indonesian Medical Association (IDI) Padang Branch conducted field observations and semi-structured interviews with affected households at evacuation sites. Information on assistance already received and unmet priority needs was collected and used to guide the procurement and distribution of relief items. Most affected households had already received temporary shelter, food, and clean water. However, essential personal items—including towels, baby supplies, underwear, blankets, prayer equipment, umbrellas, and raincoats—remained insufficient. Implementing Rapid Needs Assessment enabled the humanitarian team to provide targeted assistance, complement existing relief efforts, minimize duplication, and address overlooked needs. Rapid Needs Assessment improved the relevance and effectiveness of humanitarian aid distribution. Collaboration between higher education institutions and professional organizations offers a practical model for evidence-based community service in disaster response.
THE EFFECT OF ALOIN ADMINISTRATION ON FOAM CELL FORMATION IN THE KIDNEYS OF MALE MICE (MUS MUSCULUS) WITH DYSLIPIDEMIA-INDUCED OBESITY Nadya Mukhti; Ade Teti Vani; Khomeini Khomeini; Nadia Purnama Dewi; Dessy Abdullah; Rosmaini Rosmaini
Nusantara Hasana Journal Vol. 6 No. 1 (2026): Nusantara Hasana Journal, June 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i1.2255

Abstract

Dyslipidemia and obesity are major metabolic disorders characterized by abnormal lipid metabolism, chronic inflammation, and oxidative stress, all of which contribute to progressive renal injury. Excessive accumulation of oxidized low-density lipoprotein (ox-LDL) promotes macrophage infiltration and foam cell formation within renal tissue, accelerating glomerular damage and increasing the risk of chronic kidney disease. Aloin, the principal anthraquinone glycoside isolated from Aloe vera, possesses potent antioxidant and anti-inflammatory properties that may attenuate oxidative injury and inhibit foam cell formation. This study aimed to investigate the effect of oral aloin administration on renal foam cell formation in male Mus musculus with dyslipidemia-induced obesity. A true experimental study employing a posttest-only control group design was conducted using male mice with experimentally induced dyslipidemia and obesity. Animals were randomly allocated into control and treatment groups. The treatment group received oral aloin for 28 consecutive days following dyslipidemia induction. Kidney tissues were collected for histopathological examination using Hematoxylin–Eosin staining. Foam cell formation was evaluated microscopically, and differences between groups were analyzed using the Independent Samples t-test with a significance level of p < 0.05. Histopathological analysis demonstrated that aloin administration reduced renal foam cell formation compared with the untreated control group. The treatment group exhibited approximately 25% foam cell formation, whereas the control group demonstrated approximately 93.8%. These findings suggest that aloin suppresses lipid accumulation and inflammatory responses within renal tissue through its antioxidant activity. Nevertheless, the therapeutic effect remained lower than that reported for atorvastatin, indicating that aloin is more appropriately considered a complementary rather than a replacement therapy. Oral administration of aloin effectively reduced foam cell formation in the kidneys of dyslipidemia-induced obese male mice. The protective effect is likely mediated through antioxidant activity, inhibition of lipid peroxidation, and attenuation of inflammatory processes.
Antibiotic-Resistant Lactic Acid Bacteria Pediococcus acidilactici Isolated from Buffalo’s Milk Fermentation (Dadiah) Bukittinggi, West Sumatera Nadia Purnama Dewi; Dessy Abdullah; Yudha Endra Pratama
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 10, No 2: Jurnal Pembelajaran Dan Biologi Nukleus July 2024
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v10i2.5699

Abstract

The use of antibiotics is still carried out in the health world so that it will cause a big problem, namely antibiotic resistance. The use of antibiotics has also been limited but cannot be stopped. The use of probiotics as therapy in the world of health is increasing every year, so it is necessary to study the combination of antibiotics and probiotics so as not to reduce the effectiveness of probiotics later. This study aims to determine the resistance ability of lactic acid bacteria (LAB) isolates from Buffalos Milk Fermentation (called as dadiah) Bukittinggi against antibiotics. This research uses a descriptive, experimental method where the observations made are related to the total mass of isolates per ml and the clear zone of LAB isolates from dadiah Bukittinggi against antibiotics. In this study, five types of LAB isolates from dadiah Bukittinggi were used, and it was found that the total mass of isolates ranged from 4-194 x108 CFU/ml. In addition to antibiotic resistance, it was known that dadiah LAB isolates resisted Kanamycin and Penicillin by 75%. While on the antibiotic chloramphenicol, ampicillin and tetracyclin, the four isolates are suspect to the antibiotic. The five LAB isolates of dadiah used in the study, DS1 isolate had the best total mass and was resistant to kanamycin and penicillin
PENGENALAN ISI PIRINGKU DENGAN METODE PENDEKATAN SENI GAMBAR DI SMP YARI PADANG Ade Teti Vani; Irwan Triansyah; Nadia Purnama Dewi; Dessy Abdullah; Aryaldi Zulkarnaini
Nusantara Hasana Journal Vol. 3 No. 8 (2024): Nusantara Hasana Journal, January 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i8.1048

Abstract

Motivation/Background: The contents of Isi Piringku determine the nutritional status of adolescents. The wrong type, and the amount of food will cause malnutrition problems in adolescents. Introduction to the method of drawing art is effective for teenagers because drawing art includes learning to play. This method makes it easier to accept the concept of Fill My Plate. The purpose of the service activity is to provide knowledge about the contents of my plate as the first step in implementing a nutrition-conscious attitude for YARI Padang Junior High School teenagers. Method: The method of service is in the form of counseling and workshops. Counseling is carried out at the beginning and end of service. Workshops in the form of drawing art are given as core activities. Results: The results of dedication were obtained by only 5% of students who just learned about the contents of Isi Piringku. During the workshop 100% of students can analyze the contents of Isi Piringku and at the end of the service, 100% of students can analyze the contents of Isi Piringku. Conclusions: The conclusion of this devotion is that the art of drawing effectively increases the knowledge of the contents of my plate. Furthermore, the devotion of Isi Piringku can be continued with a food workshop Isi Piringku.
KADAR KATEKIN DAN AKTIVITAS ANTIOKSIDAN GAMBIR (UNCARIA GAMBIR ROXB.) DI INDONESIA: TINJAUAN LITERATUR 10 TAHUN TERAKHIR (2015-2025) Ade Teti Vani; Irwan Triansyah; Nadia Purnama Dewi; Dessy Abdullah; Aryaldy Zulkarnaini
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1862

Abstract

Indonesia is the world’s largest producer of gambier (Uncaria gambir Roxb.), which is rich in catechin, a major bioactive compound with strong antioxidant activity. Variations in catechin content and antioxidant activity of Indonesian gambier are influenced by geographical origin, plant characteristics, and processing and extraction methods. This study aims to comprehensively review the catechin content and antioxidant activity of Indonesian gambier based on scientific publications from the last decade (2015–2025). A narrative literature review method was applied by collecting relevant articles from Google Scholar, ScienceDirect, PubMed, and Garuda databases. Selected studies were original research articles reporting quantitative data on catechin levels and/or antioxidant activity of gambier originating from Indonesia. The results indicate that Indonesian gambier, particularly from West Sumatra, exhibits high catechin content and strong antioxidant activity, although considerable variation exists among regions and extraction techniques. Advanced extraction and purification methods, including solvent optimization and ultrasonic-assisted extraction, were shown to enhance catechin concentration and antioxidant capacity. Indonesian gambier has significant potential as a natural antioxidant source, highlighting the need for quality standardization and further development of processing technologies to support value-added utilization and downstream product development.
DIABETES GESTASIONAL SEBAGAI PREDIKTOR DINI PENYAKIT KARDIOMETABOLIK JANGKA PANJANG: TINJAUAN LITERATUR Wisda Widiastuti; Dessy Abdullah; Aryaldy Zulkarnaini; Arief Rinaldy; Desi Aliefia; Gangga Mahatma
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1864

Abstract

Gestational diabetes mellitus (GDM) has long been regarded as a transient metabolic disorder limited to pregnancy. However, growing scientific evidence indicates that GDM represents an early marker of long-term metabolic vulnerability in women. This literature review aims to synthesize current evidence on the association between GDM and the risk of type 2 diabetes mellitus, cardiovascular disease, and other metabolic disorders after pregnancy, as well as its implications for postpartum care and interdisciplinary collaboration. A literature search was conducted using the PubMed, Scopus, and Web of Science databases, focusing on articles published over the past ten years. The review findings show that women with a history of GDM have a significantly increased risk of developing type 2 diabetes mellitus, as well as a higher risk of cardiovascular disease compared with women without a history of GDM, even among those who do not progress to overt diabetes. The underlying mechanisms include persistent insulin resistance, pancreatic β-cell dysfunction, chronic low-grade inflammation, the role of the placenta, and the potential contribution of the gut microbiota. In conclusion, GDM should be understood as an early predictor of long-term cardiometabolic disease. Structured and collaborative postpartum care involving obstetrics and internal medicine is essential to reduce the future burden of disease.