Claim Missing Document
Check
Articles

Found 35 Documents
Search

FERMENTED GOAT MILK AND STINGLESS BEE HONEY MODULATE INTESTINAL LACTIC ACID BACTERIA AND BODY WEIGHT IN DIABETIC RATS MODEL Rinita Amelia; Dessy Abdullah; Ira Suryanis; Yudha Endra Pratama; Melya Susanti
Nusantara Hasana Journal Vol. 6 No. 2 (2026): Nusantara Hasana Journal, July 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i2.2301

Abstract

Diabetes mellitus is associated with intestinal dysbiosis and body-weight loss. Fermented goat milk provides probiotic lactic acid bacteria (LAB), whereas stingless bee honey contains oligosaccharides with prebiotic potential. This study evaluated their effects on body weight and intestinal LAB in diabetic rats. Streptozotocin-induced diabetic Sprague Dawley rats were assigned to five groups (n = 6): healthy control (K−), diabetic control (K+), fermented goat milk (P1, 1 mL/day), stingless bee honey (P2, 0.4 mL/day), and fermented goat milk supplemented with 5% stingless bee honey (P3, 1 mL/day) for 8 weeks. Body-weight change and intestinal LAB counts were analyzed using one-way ANOVA and Tukey's HSD test. Body-weight change differed significantly among groups (p = 0.0155). P2 showed the greatest weight gain, whereas K+ exhibited the greatest weight loss. Intestinal LAB counts also differed significantly (p < 0.001), with P2 showing the highest LAB population, followed by P1 and P3. Fermented goat milk and stingless bee honey increased intestinal LAB and alleviated diabetes-associated body-weight loss, with stingless bee honey producing the greatest overall effect.
INTERLEUKIN-6 AS A BIOMARKER OF INFLAMMAGING IN AGED RATS (RATTUS NORVEGICUS): A SYSTEMATIC LITERATURE REVIEW Dessy Abdullah; Rinita Amelia; Ira Suryanis; Melya susanti; Maryetti marwazi; Yudha pratama
Nusantara Hasana Journal Vol. 6 No. 1 (2026): Nusantara Hasana Journal, June 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i1.2303

Abstract

Background: Aging is a complex biological process characterized by declining adaptive capacity, immune dysfunction, cellular damage, and persistent low-grade inflammation known as inflammaging. Interleukin-6 (IL-6) is widely used to assess age-related inflammatory changes; however, findings in aged rat models remain inconsistent and may vary according to strain, age, tissue, sex, metabolic status, and inflammatory stimuli. Objective: This systematic review evaluated changes in IL-6 levels or expression in aging Rattus norvegicus compared with younger rats and explored biological and experimental factors contributing to response heterogeneity. Methods: The review followed the PECO framework and PRISMA 2020 guidelines. Literature searches were conducted in PubMed/MEDLINE, Scopus, Web of Science Core Collection, ScienceDirect, and Google Scholar. Studies involving rats with identifiable age groups and IL-6 as an outcome were included. Risk of bias was planned using the SYRCLE Risk of Bias Tool. Due to substantial heterogeneity in age, strain, tissue, inflammatory stimuli, and IL-6 assessment methods, findings were synthesized narratively. Results: Evidence indicated heterogeneous age-related IL-6 responses. Several studies reported increased IL-6 in aged rats, particularly following lipopolysaccharide stimulation, whereas others found no consistent increase in plasma IL-6 despite increased tissue expression. Conclusion: IL-6 may reflect inflammatory changes during aging, but it is not a universally elevated biomarker in aged rats. Its interpretation should consider tissue compartment, strain, age, sex, metabolic status, and inflammatory stimuli.
EFFECTIVENESS OF GALO-GALO HONEY SUPPLEMENTATION COMBINED WITH IRON TABLETS ON HEMOGLOBIN LEVELS AMONG FEMALE MIDWIFERY STUDENTS Ira Suryanis; Rinita Amelia; Dessy Abdullah; Fauziah Fadhilatul Rizka Yudha; Yudha Endra Pratama
Nusantara Hasana Journal Vol. 6 No. 2 (2026): Nusantara Hasana Journal, July 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i2.2319

Abstract

Background: Anemia remains an important nutritional problem among adolescent girls and young women. Female university students are vulnerable to iron deficiency because of menstrual blood loss, inadequate dietary iron intake, and irregular eating patterns. This study evaluated the effectiveness of Galo-Galo honey supplementation combined with iron tablets in increasing hemoglobin levels among female midwifery students. Methods: A quantitative pre-experimental study with two pretest-posttest groups was conducted among 38 female students of the Bachelor of Midwifery Program, Faculty of Health Sciences, Universitas Baiturrahmah, Padang. Participants were allocated into two groups of 19 students. One group received iron tablets combined with Galo-Galo honey, while the comparison group received iron tablets. Hemoglobin was measured before and after the intervention using an EasyTouch GCHb device. Results: In the iron tablet plus Galo-Galo honey group, mean hemoglobin increased from 12.4 ± 1.2534 g/dL before intervention to 13.2 ± 1.2810 g/dL after intervention, representing a mean increase of 0.8 g/dL (p<0.001). In the iron-tablet group, mean hemoglobin increased from 11.9 ± 0.957 g/dL to 12.6 ± 0.875 g/dL, representing a mean increase of 0.7 g/dL (p<0.001). Conclusion: Both interventions were associated with significant increases in hemoglobin levels. The observed increase was numerically greater in the combination group; however, the source document does not report a statistical test directly comparing the magnitude of hemoglobin change between groups. Further controlled studies with larger samples are required to establish the additional effect of Galo-Galo honey beyond iron supplementation.
Penguatan Layanan Posyandu Lansia melalui Skrining Tekanan Darah, Hemoglobin, dan Status Gizi di Wilayah Kerja Puskesmas Anak Air Kota Padang : Pengabdian Rinita Amelia; Ira Suranis; Dessy Abdullah; Yudha Endra Pratama
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 5 No. 1 (2026): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 5 Nomor 1 (Juli 2026 -
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v5i1.7682

Abstract

Populasi lanjut usia (lansia) di Indonesia terus meningkat, sementara akses layanan kesehatan promotif dan preventif bagi kelompok ini di tingkat masyarakat masih perlu diperkuat, termasuk di wilayah kerja Puskesmas Anak Air Kota Padang. Kegiatan pengabdian kepada masyarakat ini bertujuan menguatkan layanan Posyandu Lansia melalui skrining tekanan darah, kadar hemoglobin (Hb), dan status gizi. Kegiatan dilaksanakan pada Sabtu, 8 Juli 2026, melibatkan 25 peserta lansia yang dihadirkan oleh pihak Puskesmas sebagai perwakilan dari setiap posyandu di wilayah kerja tersebut. Skrining tekanan darah menggunakan tensimeter digital, kadar Hb diukur dengan stick Hb, sedangkan berat badan dan tinggi badan diukur oleh mahasiswa kedokteran dibantu bidan dan perawat Puskesmas. Hasil menunjukkan rerata usia peserta 69,40 ± 6,50 tahun dengan mayoritas perempuan (76,0%). Pada status gizi, 40,0% peserta berada pada kategori obesitas dan 12,0% kategori kurus. Pada tekanan darah, sebagian besar peserta berada pada kategori prehipertensi hingga hipertensi derajat 1 (32,0% dan 36,0%), sementara 8,0% berada pada kategori krisis hipertensi. Pada pemeriksaan Hb, 44,0% peserta menunjukkan hasil pada rentang anemia (40,0% ringan dan 4,0% sedang). Temuan ini menegaskan pentingnya skrining rutin di Posyandu Lansia sebagai upaya deteksi dini, disertai edukasi dan koordinasi rujukan bersama Puskesmas dan kader untuk memperkuat pemantauan kesehatan lansia secara berkelanjutan
EVALUASI PELATIHAN KESIAPSIAGAAN KESEHATAN IBU DAN ANAK BAGI KADER POSYANDU DAN BIDAN PADA SITUASI BENCANA DI KABUPATEN PADANG PARIAMAN Dessy Abdullah; Rinita Amelia; Ira Suryanis; Yudha Endra Pratama
Nusantara Hasana Journal Vol. 6 No. 3 (2026): Nusantara Hasana Journal, August 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v6i3.2320

Abstract

Pregnant women, postpartum women, infants, and toddlers are among the vulnerable groups that face increased health risks during disasters. Posyandu volunteers and midwives play a strategic role in maintaining the continuity of maternal and child health (MCH) services during emergency response periods; however, their capacity for disaster preparedness still needs to be strengthened. To implement and evaluate training and mentoring activities regarding the roles of volunteers and midwives in MCH preparedness during disaster situations. This community service activity involved 25 participants (21 Posyandu cadres, 4 midwives) in the service area of the Lubuk Alung Community Health Center, Padang Pariaman Regency. Evaluation was conducted through pre- and post-tests of knowledge (15 multiple-choice questions) and a training implementation evaluation questionnaire (15 statements on a 1–5 Likert scale). The data were analyzed descriptively. Participants’ average knowledge scores before the training were already very high (mean 14.88 out of 15; 99.20%) and remained high after the training (mean 14.72 out of 15; 98.13%), with an average change of −0.16. No participant’s score increased; 22 participants (88%) showed no change in their scores, and 3 participants (12%) experienced a decrease of 1–2 points. The training evaluation revealed a very positive response (overall mean of 4.70 on a 5-point scale), with the highest appreciation for the relevance of the material and the comfort of the training venue. The activity was carried out well and received a positive response from participants. The lack of an increase in knowledge scores is likely related to the participants’ already very high baseline knowledge before the training began, rather than an indication of the training’s failure. Training and mentoring remain relevant as part of strengthening community-based maternal and child health (MCH) disaster preparedness.