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An ABC-VEN Analysis for Outpatient Medicines Use in the Department of Internal Medicine at Universitas Airlangga Teaching Hospital Zedny Norachuriya; Budi Suprapti; Dinda Monika Nusantara Ratri; Cahyo Wibisono Nugroho; Yosiyanita Safari
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 2 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i22024.184-191

Abstract

Background: Application of the ABC-VEN method in evaluating drug planning can increase efficiency and ensure optimal medicine availability and stable access to medications. Objective: To analyze ABC-VEN combinations to examine the profile of medicine use in the internal medicine department. Methods: This was an observational study with retrospective prescription data from outpatients in the Internal Medicine Department from January to March 2020. Collected data included the type, number of medicines, and medicine prices. Patients undergoing chemotherapy and retroviral therapy for HIV were excluded from the study. Subsequently, an ABC-VEN analysis was performed. Results: Of 4,242 prescription samples, 188 types of medicines were used. Based on the drug use evaluation with ABC analysis, category A contained 23 items (12.17%), category B contained 35 items (18.52%), and category C contained 130 items (69.31%). The ABC analysis for investment value found that category A contained eight items (4.23%), category B contained 22 items (11.64%), and 158 items (84.13%). Based on the VEN analysis, Group V had six medicine items, Group E had 152 medicine items, and Group N had 30 medicine items. The ABC-VEN investigation showed that there were eight, 151, and 29 items of medicines in Categories I, I, and III, respectively. Conclusion: Although there are medicines that are highly used, their investment value is quite low. The use of the ABC-VEN method to evaluate medicine use is crucial for organizing and controlling the medicine supply.
Exploring Side Effects of Warfarin in Outpatients at Tertiary Hospital in Indonesia Fatimatuz Zahra Oviary Satryo; Dewi Wahyuni; Budi Suprapti; Wenny Putri Nilamsari; Mochamad Yusuf Alsagaff; Dewi Makmuroh Nurul Qomar Purnamawati; Bambang Subakti Zulkarnain
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 2 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i22025.142-150

Abstract

Background: Patients with atrial fibrillation, venous thromboembolism, valvular disease, cardioembolic stroke, and acute myocardial infarction are prescribed the oral anticoagulant warfarin to treat thrombi. To guarantee its efficacy and safety, anticoagulants must be closely monitored. Furthermore, warfarin has a narrow therapeutic index, which increases the risk of side effects, particularly in the early stages of treatment. Objective: This study aimed to analyze the incidence of warfarin side effects in outpatients at Dr. Soetomo General Hospital. Methods: A retrospective cross-sectional design was adopted for outpatients at the Cardiology Department of Dr. Soetomo General Hospital from March to May 2023. Data were collected on the incidence of side effects in outpatients who received warfarin for a minimum of one month through an interview process. Other data, including age, sex, duration of warfarin therapy, comorbidities, and INR at the last scan, were extracted from medical records. The Chi-Square test was used to examine the data. Results: The results showed that 88 patients (42.7%) had side effects of bleeding (126 events). These included gum bleeding (22.3%), hematoma (20.4%), melena (7.7%), menometrorrhagia (2.4%), epistaxis (1.9%), hematuria (1.5%), hematemesis (1.0%), hemoptysis (1.0%), spontaneous venous bleeding  (1.0%), hematochezia (0.5%), hemostasis during blood sampling  (0.5%), tongue bleeding  (0.5%), and subconjunctival bleeding  (0.5%). Conclusion: The incidence of side effects during warfarin treatment was high, accounting for approximately 42.7% of cases. Furthermore, one patient experienced more than one side effect.
Change in Adherence and Glycemic Control Following WhatsApp-Based Education and Interactive Reminders among Diabetes Patients Diyah Wahyuni; Budi Suprapti; Ramadi Satryo Wicaksono; Abdul Kadir Jaelani; Vini Siane Tanaem
Journal of Public Health and Pharmacy Vol. 6 No. 3 (2026): In Progress
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v6i3.10072

Abstract

Introduction: Type 2 diabetes mellitus (DM) is a non-communicable disease with increasing prevalence and low adherence globally. Therefore, this study aims to evaluate changes in medication adherence and glycemic control after a WhatsApp-based education and interactive reminders among outpatients receiving insulin therapy. Methods: A pre-experimental study used a prospective one-group pre-test-post-test design among outpatients receiving insulin in a hospital. The intervention included DM education at the initial meeting, followed by educational videos and weekly interactive reminders provided through WhatsApp for 6 weeks. Patient knowledge was assessed with Diabetes Knowledge Questionnaire (DKQ) and adherence to medication was assessed using Adherence to Refills and Medications Scale (ARMS). Glycemic control indices (fasting blood glucose (FBG), two hours of postprandial blood glucose (2hPPBG), glycated hemoglobin (HbA1c)) were measured before and after the intervention. Additionally, a paired t-test was used to measure the effect of the intervention on knowledge, adherence, and glycemic control indices. Results: Among the 122 patients who fulfilled the inclusion criteria, there was a significant increase in knowledge (p < 0.001), with the proportion of highly knowledgeable patients rising from 19.7% to 38.5%. The increase in adherence to medication from 30.3% to 39.3% was not statistically significant (p = 0.228). Glycemic control indices showed a significant improvement (p < 0.001), with mean HbA1C, FBG, and 2hPPBG decreasing from 8.63% to 7.85%, 152.18 mg/dl to 138.72 mg/dl, and 268.84 mg/dl to 228.66 mg/dl, respectively. Conclusion: Following the 6 weeks WhatsApp-based education and interactive reminders, improvement were observed in patient knowledge and glycemic control indices, but medication adherence did not change significantly. This study lacked a control group, the findings represent observed changes after the study period and require confirmation in controlled studies with longer follow-up.
Co-Authors Abdul Kadir Jaelani Abdul Rahman Bahmid Aditiawardana Aditiawardana, Aditiawardana Alsagaff, M. Yusuf Andarsari, Mareta R. Aniek S. Budiatin Ardiana, Shafira muti Arfiani, Ria Fitrah Arief Bachtiar Arina Deri Puspita Sari Arina Dery Puspitasari Ayunda Nur Hidayatiningsih Azril O. Ardhiansyah Bambang Subakti Zulkarnain Bella Donna Perdana Putra Budiatin, Aniek S. Bulqiah, Andi Cahyo Wibisono Cahyo Wibisono Nugroho Chrysnanda Maryska Cinantya Meyta Sari Cinantya Meyta Sari Cinantya Meyta Sari Dewi Damayanti Dewi Makmuroh Nurul Qomar Purnamawati Dewi W. Shinta Dewi Wahyuni Dewi Wara Shinta Didik Hasmono Dinda Monika Nusantara Ratri Dinda Monika Nusantara Ratri Diyah Wahyuni Diyah Wahyuni Eddy Rahardjo Fathia Ramadiani Fatimatuz Zahra Oviary Satryo FITRIANI, VICTORIA YULITA Hapsari, Pharmasinta P. Hartono, Frenky Hidayati, Movita I Gde Raka Widiana Idha, Arofa Idha, Arofa Junaidi Khotib Khusnul Fitri Hamidah Kusmiati, Tutik M. Yusuf M. Yusuf Assegaf Mahardian Rahmadi Mansur, Mifta Marcha Debby Saraswati Marcha Debby Saraswati Marcha Debby Saraswati Mareta R. Andarsari Mareta Rindang Andarsari Mochamad Yusuf Alsagaff Muhammad Amin Mulya Sundari Ni Made Amelia R. Dewi Ni Made Mertaniasih Nia Widyasari Novan Y. I. Pratama Nurmainah Nurmainah Nurmainah Nurmainah Pharmasinta P. Hapsari Pharmasinta Putri Hapsari Prasetya, Anak Agung Ngurah Putra Riana Prastuti Asta Wulaningrum Purwiningtyas, Mida Putranto, J.Nugroho Eko Rahmawati Raising Ramadi Satryo Wicaksono Ramadiani, Fathia Retna Dwi Puspitarini S. Soedarsono Santi, Bayu Dharma Santoso, Agustinus Santoso, Agustinus Sarah Puspita Atmaja Sari, Cinantya Meyta Selvia Febriana Astuti Sensusiati, Anggraini Dwi Shafira Muti Ardiana Shanti, Bayu Dharma Shanti, Bayu Dharma Shinta, Dewi W. Sjamsiah, Siti Sjamsiah, Siti Sofiati Diah Baisuni Suharjono Suharjono Susilo, Dwi Hari Thomas Erwin Christian Junus Huwae Toetik Aryani UMI FATMAWATI Vini Siane Tanaem Wenny Putri Nilamsari WENNY PUTRI NILAMSARI, WENNY PUTRI Yosiyanita Safari Yudistira Nurrizky Grahitaning Putra Rohmaana Yulistiani Yulistiani Yulistiani Yulistiani, Yulistiani Zamrotul Izzah Zedny Norachuriya Zuhri, Muhammad Isnaini