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Journal : Jaringan Laboratorium Medis

Profil SGOT, SGPT, dan Kreatinin Pada Pasien MDR TB di RS KRMT Wongsonegoro Semarang Surati, Surati; Khairunnisa, Afifah; Setyaji, Yoki; Maulana, Mochamad Rizal
Jaringan Laboratorium Medis Vol 6, No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10951

Abstract

Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Tuberculosis apabila is not treated immediately or the treatment is not complete can result in complications leading to death. Multidrugs resistant tuberculosis (MDR-TB) is one of the complications where the germ Mycobacterium tuberculosis can no longer bekilled with several Anti-Tuberculosis Drugs (OAT). The prevalence of MDR-TB cases in Semarang City has increased from 35 cases in 2017 to 79 cases in 2018. MDR-TB therapy takes a longer time, which is about 18-24 months. Prolonged exposure to drugs can affect body functions, especially the kidneys and liver organs which play a role in the process of removing toxins and metabolic waste. This study aims to determine the health profile of the kidney and liver organs of MDR TB sufferers through the SGOT SGPT and Creatinine parameters and describe them based on age and age range. This research is adescriptive quantitative research with a cross-sectional approach. Sampling using total samples of 18 patients. The results showed that 33% (n= 6) of patients had increased levels of SGOT and SGPT, while examination of creatinine levels showed that 33% of patients had kidney problems. Men have upnormal SGOT and SGPT levels of 40% ( n=4) compared to women, which is 25% (n=2), while upnormal creatinine levels in men are 40% (n=4) while in women it is 50% (n = 8). Patients over the age of 46 years have the most levels of SGOT SGPT and upnormal creatinine, which is 61% (n=4). The results showed that age and gender had an effect on increasing SGOT SGPT and Creatinine levels in MDR-TB patients.
Gambaran Escherichia Coli Pada Air Sumur Gali Fahrurriza, Febry Risdhityatama; Surati, Surati
Jaringan Laboratorium Medis Vol. 2 No. 1 (2020): May 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i1.5273

Abstract

Most of the wells are still used as a source of drinking water. This well is widely used in the village of Rejosari Grobogan. Regulation of the Minister of Health No. 492 of 2010 concerning the Requirements for Quality of Drinking Water is 0 per 100 ml of sample. The existence of Escherichia coli in water sources affects water quality which has an impact on consumer health, so it is necessary to know whether the quality of water sources from dug wells meets drinking water standards. To find out whether Escherichia coli bacteria were present in the well water of Rejosari Grobogan Village. The research conducted included a type of quantitative research with a descriptive design. The sample used was 11 samples. The results of the examination showed that there was an Escherichia coli bacterium in the well water of Rejosari Grobogan Village with an average number of bacteria <1.8 per 100 ml of sample. Research on samples was carried out using the Most methodProbable Number (MPN). Rejosari Grobogan village water wells were found to contain Escherichia coli bacteria and not meet water quality standards in accordance with Minister of Health Regulation No. 32 of 2017.
Gambaran Kadar Kolesterol pada Akseptor Kontrasepsi Suntik Wulandari, Pupung Cahya; Surati, Surati
Jaringan Laboratorium Medis Vol. 1 No. 2 (2019): November 2019
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v1i2.5448

Abstract

Based on the population census data from 2016, there are more than 258 million people and it’s projected will continue grow. Family planning programs for family planning total and restriction on the use of contraceptive. The number of fertile age couple in the province of central java in 2016 was 6.727.894 of all fertile age couples of 78.6% active family planning participants. The type of contraception that is often used is injection at 54.2%. The most many used contraceptive injection is contraceptive injection 3 month (DMPA). In Semarang City, Pedurungan district the most number of fertile age couples. The village with the most injectable contraceptive acceptors is Tlogosari Kulon Village. Injectable contraception causes changes in fat metabolism through changes in cholesterol levels. Descriptive type research with cross sectional. The study sample was 25 injectable contraceptive acceptors 3 months. The result examination of cholesterol levels in injectable cholesterol levels in injectable contraceptive acceptors 3 months on average cholesterol levels is 209.5 mg/dl, as many 12 acceptor contraceptive injective 3 months had normal cholesterol levels (48%), and as many 13 acceptor contraceptive injective 3 months had above normal cholesterol levels (52%). 3 month injection contraception can increase cholesterol levels.
Gambaran Kadar SGPT pada Pasien Tuberculosis Multidrug Resistant (TB-MDR) Damayanti, Meisika; Surati, Surati
Jaringan Laboratorium Medis Vol. 2 No. 2 (2020): November 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i2.7687

Abstract

Multidrug Resistant Tuberculosis (MDR-TB) has recently become a health threat in Indonesia. The clinical management of MDR TB is more complicated than that of ordinary TB. Hepatotoxicity or commonly known as Anti-Tuberculosis Drug-induced Hepatotoxicity (ATDH) is a serious effect of OAT that often occurs. The basic parameter for diagnosing or following up the presence of impaired liver function is the SGPT examination. The purpose of this study was to describe the level of SGPT in MDR-TB patients at the Kendal District Health Center. This study is an observational (non-experimental) study with descriptive research criteria with a cross sectional approach which was conducted on 7 MDR-TB patients at Kendal I Health Center, Kaliwungu Health Center, and South Kaliwungu Health Center with total sampling technique. The results of the study: obtained SGPT levels in 7 patients with MDR-TB there were 7 research respondents (100%) had normal SGPT levels with the lowest level of 2.17 U/L and the highest level of 37.75 U/L and the average level of SGPT ie 18.01 U/L. TB mostly attacks the age group of 56-65 years (57%). Males (57%) were the patients with the most TB cases. The most OAT consumption time was in the continuation phase (100%). Diabetes is a disease that often accompanies TB patients. The conclusion of this study is that from 7 research subjects, MDR-TB patients had SGPT levels that were in the normal range.
Hubungan Antara Higiene Sanitasi Terhadap Kontaminasi Telur Cacing Non STH Pada Sayur Lalapan di Warung Makan Setyowatiningsih, Lilik; Wikandari, Ririh Jatmi; Surati, Surati
Jaringan Laboratorium Medis Vol. 4 No. 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8325

Abstract

Fresh vegetables can be a source of transmission of worm infections to humans. The behavior of washing fresh vegetables that are not good by housewives and sellers of fresh vegetables in food stalls becomes large in transmitting worm infections if there are worm eggs that are still attached to fresh vegetables. The most common contamination found in fresh vegetables were eggs of the intestinal nematode Soil Transmitted Helminths (STH) as well as non-STH and trematodes. The purpose of this study was to determine the relationship between sanitation hygiene and contamination of non-STH worm eggs in fresh vegetables at food stalls in Semarang City. This type of research is an observational study with a cross sectional approach. Based on the results of laboratory tests, from a total of 165 samples examined, eggs of non-STH worms with species of Fasciola sp and Toxocara sp were found in 45 food stalls selling fresh vegetables. Based on bivariate analysis, there was no significant relationship between personal hygiene (p = 0.071) and environmental sanitation (p = 0.334) on contamination of non-STH worm eggs in fresh vegetables in food stalls in Pedurungan District, Semarang.
Profil Hasil Pemeriksaan Dahak Pada Pasien Multidrug-Resistant Tuberculosis (MDR-TB) Nadza, Alisa Khodrun; Surati, Surati
Jaringan Laboratorium Medis Vol. 4 No. 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8526

Abstract

TB patients who do not adhere to OAT treatment can lead to resistance and become MDR-TB and add to the burden of TB management globally. TB control programs including microscopic sputum examination are important for diagnosis, evaluation, follow-up treatment, and follow-up. The results of the sputum examination used the IUATLD scale as an interpretation of the results and the reporting was negative, scanty, positive one, positive two, and positive three according to the number of TB germs found. The results of the sputum examination to determine the classification of the patient, the decision to start treatment, and the patient's recovery. At the step of treatment for MDR-TB patients, the results of sputum examination are an indicator to determine the success rate of treatment which is marked by the conversion of BTA. Research objectives is to determine the description of the results of sputum examination in Multidrug-Resistant Tuberculosis (MDR-TB) patients at the Kendal District Health Center. Research methods is observational research with descriptive research criteria through a cross sectional approach. Respondents of the study were multidrug-resistant tuberculosis (MDR-TB) patients from three health centers in Kendal district with the highest case prevalence. The study respondents were 7 MDR-TB patients. All study respondents, totaling 7 MDR-TB patients (100%), were included in the advanced step of treatment and showed negative sputum examination results. All study respondents (100%) showed that the results of microscopic sputum examination were negative, which means that BTA conversion occurred at the advanced treatment step.
Perbandingan Persentase Risiko Meninggal pada Pasien Covid-19 Komorbid TBC dengan Komorbid Lainnya di Kabupaten Pati Istananta, Randi Eka; Budiharjo, Teguh; Surati, Surati
Jaringan Laboratorium Medis Vol. 5 No. 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9829

Abstract

Corona Virus Disease 2019 (COVID-19) is a disease that has never previously been found in humans and is a new type of disease. The virus that causes COVID-19 is called Sars-CoV-2. It was found that patients experienced increased mortality due to COVID-19 because they had comorbid diseases. COVID-19 patients who have one comorbid disease are at risk of death up to 6.5 times higher than COVID-19 patients without comorbidities. Pulmonary TB is a comorbidity that can make a person more susceptible to contracting COVID-19 with severe symptoms. Apart from attacking the lungs, COVID-19 also damages the lungs. Damaged lungs prevent the body's organs from getting enough oxygen, which can trigger organ damage that can cause death. The aim of this study was to compare the percentage risk of death in COVID-19 patients who had comorbid TB disease with COVID-19 patients who had comorbid kidney disease and DM in the Pati area, Central Java. This research can be a reference for data regarding the percentage risk of death in COVID-19 patients with comorbidities. This research uses a descriptive, observational research design. The samples in this study were COVID-19 sufferers who had comorbid TB, comorbid kidney disease and comorbid DM. The sample population during the period January to December 2021 was 998. The sample was determined using the Slovin formula with a total of 135 samples with a sampling quota taken. Results Comorbid TB has a percentage risk of death of 40%, comorbid kidney has a percentage risk of death of 33.3%, and comorbid DM has a percentage risk of death of 6.8%. Comorbid TB is a comorbid that has the highest percentage risk of death, so intensive care is important for sufferers.
Profil SGOT, SGPT, dan Kreatinin Pada Pasien MDR TB di RS KRMT Wongsonegoro Semarang Surati, Surati; Khairunnisa, Afifah; Setyaji, Yoki; Maulana, Mochamad Rizal
Jaringan Laboratorium Medis Vol. 6 No. 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10951

Abstract

Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Tuberculosis apabila is not treated immediately or the treatment is not complete can result in complications leading to death. Multidrugs resistant tuberculosis (MDR-TB) is one of the complications where the germ Mycobacterium tuberculosis can no longer bekilled with several Anti-Tuberculosis Drugs (OAT). The prevalence of MDR-TB cases in Semarang City has increased from 35 cases in 2017 to 79 cases in 2018. MDR-TB therapy takes a longer time, which is about 18-24 months. Prolonged exposure to drugs can affect body functions, especially the kidneys and liver organs which play a role in the process of removing toxins and metabolic waste. This study aims to determine the health profile of the kidney and liver organs of MDR TB sufferers through the SGOT SGPT and Creatinine parameters and describe them based on age and age range. This research is adescriptive quantitative research with a cross-sectional approach. Sampling using total samples of 18 patients. The results showed that 33% (n= 6) of patients had increased levels of SGOT and SGPT, while examination of creatinine levels showed that 33% of patients had kidney problems. Men have upnormal SGOT and SGPT levels of 40% ( n=4) compared to women, which is 25% (n=2), while upnormal creatinine levels in men are 40% (n=4) while in women it is 50% (n = 8). Patients over the age of 46 years have the most levels of SGOT SGPT and upnormal creatinine, which is 61% (n=4). The results showed that age and gender had an effect on increasing SGOT SGPT and Creatinine levels in MDR-TB patients.