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All Journal ACTA VETERINARIA INDONESIANA Jurnal Perikanan Universitas Gadjah Mada Jurnal Pengabdian Kepada Masyarakat MEMBANGUN NEGERI Community Development Journal: Jurnal Pengabdian Masyarakat Spizaetus: Jurnal Biologi dan Pendidikan Biologi Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal EduHealth Sahabat Sosial: Jurnal Pengabdian Masyarakat Barongko : Jurnal Ilmu Kesehatan International Journal of Health Sciences BHAKTI JIVANA
Meillisa C. Mainassy
Biologi, Universitas Pattimura, Jl. Ir. M. Putuhena, Ambon, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Identification And Characterization Of Pathogenic Microorganisms In The Health Environment Harnia Harnia; Meillisa Carlen Mainassy; Glory Gelarich Simanjuntak; Rahmat Pannyiwi
International Journal of Health Sciences Vol. 4 No. 1 (2026): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v4i1.1141

Abstract

Healthcare facilities have the potential to be reservoirs for various pathogenic microorganisms that can cause nosocomial infections. The presence of microorganisms on the surfaces of medical devices, treatment rooms, and ambient air can increase the risk of disease transmission to patients and healthcare workers. This study aims to identify and characterize pathogenic microorganisms found in healthcare environments. The study used a descriptive laboratory design with an observational approach. Samples were taken from treatment table surfaces, door handles, medical devices, and room air using swab and air sedimentation methods. Identification was carried out through culture examination, Gram staining, and biochemical tests. The results showed the presence of pathogenic bacterial isolates such as Staphylococcus aureus. aureus, Escherichia coli, and Pseudomonas aeruginosa. Some isolates showed resistance to certain antibiotics. It was concluded that healthcare environments have the potential to be a source of infection transmission, necessitating strict infection monitoring and control.
Identification And Characterization Of Pathogenic Microorganisms In The Health Environment Harnia; Meillisa Carlen Mainassy; Glory Gelarich Simanjuntak; Rahmat Pannyiwi
International Journal of Health Sciences Vol. 4 No. 1 (2026): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Healthcare facilities have the potential to be reservoirs for various pathogenic microorganisms that can cause nosocomial infections. The presence of microorganisms on the surfaces of medical devices, treatment rooms, and ambient air can increase the risk of disease transmission to patients and healthcare workers. This study aims to identify and characterize pathogenic microorganisms found in healthcare environments. The study used a descriptive laboratory design with an observational approach. Samples were taken from treatment table surfaces, door handles, medical devices, and room air using swab and air sedimentation methods. Identification was carried out through culture examination, Gram staining, and biochemical tests. The results showed the presence of pathogenic bacterial isolates such as Staphylococcus aureus. aureus, Escherichia coli, and Pseudomonas aeruginosa. Some isolates showed resistance to certain antibiotics. It was concluded that healthcare environments have the potential to be a source of infection transmission, necessitating strict infection monitoring and control. Keywords: Pathogenic Microorganisms, Nosocomial Infections, Bacterial Identification, Health Environment
Potensi Ekstrak Etanol Daun Afrika (Vernonia amygdalina Del.) terhadap Perbaikan Kerusakan Ginjal Tikus Putih (Rattus norvegicus) yang Diberikan Sopi Petra Willem Rodnels Melatunan; Chomsa Dintasari Umi Baszary; Meillisa Carlen Mainassy
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 7 No 2 (2026): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v7i2.723

Abstract

Excessive consumption of sopi in the long term can cause various chronic diseases such as kidney failure. This study aims to determine the potential of African leaf ethanol extract in repairing sopi-induced kidney damage in white rats. The experimental design used was a completely randomized design (CRD) with five treatments. The sample was 18 mice. Groups of mice K (-), K (+), P1, P2 and P3 were induced with 1.28 ml of sopi/animal. K (+) mice were given Furosemide as a comparison. Groups P1, P2 and P3 were given ethanol extract of African leaves at doses of 1.28, 2.56 and 5.12 ml/head/day respectively. The results obtained were analyzed using analysis of variance (ANOVA) then followed by the Tukey HSD post hoc test. The results of the study showed that there was an effect of reducing creatinine levels and improving kidney damage in white mice due to administration of African leaf ethanol extract, where the effective dose was 2.56ml/head/day. So it can be concluded that the ethanol extract of African leaves at a dose of 2.56 ml/head/day has the potential to reduce creatinine levels and repair sopi-induced kidney damage in white rats, the results of which are also the same as those shown by the drug Furosemide. However, giving higher doses will be toxic to the body.
Karakterisasi Peran Bakteri Endofit Tanaman Herbal terhadap Aktivitas Antibakteri pada Mikroorganisme Patogen Manusia Eni Kurniati; Rahmat Pannyiwi; Meillisa Carlen Mainassy
Barongko: Jurnal Ilmu Kesehatan Vol. 4 No. 3 (2026): Barongko : Jurnal Ilmu Kesehatan (Juli)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v4i3.1182

Abstract

ABSTRACT Endophytic bacteria are microorganisms that live within plant tissues without causing damage to their host plants. These bacteria are known to produce various secondary metabolites that have potential as antibacterial agents. Herbal plants, as a source of bioactive compounds, also have the potential to serve as habitats for endophytic bacteria that produce antimicrobial compounds. This study aims to characterize endophytic bacteria from herbal plants and evaluate their antibacterial activity against human pathogenic microorganisms. The study used the method of isolating endophytic bacteria from herbal plant tissues, followed by antibacterial activity testing using the disc diffusion method against pathogenic bacteria such as Staphylococcus aureus and Escherichia coli. The results showed that several endophytic bacterial isolates were able to inhibit the growth of pathogenic bacteria with inhibition zones ranging from 10–18 mm. This indicates that endophytic bacteria from herbal plants have potential as a source of natural antibacterial compounds. Keywords: Endophytic Bacteria, Herbal Plants, Antibacterial, Pathogenic Microorganisms ABSTRAK Bakteri endofit merupakan mikroorganisme yang hidup di dalam jaringan tanaman tanpa menyebabkan kerusakan pada tanaman inangnya. Bakteri ini diketahui mampu menghasilkan berbagai metabolit sekunder yang memiliki potensi sebagai agen antibakteri. Tanaman herbal sebagai sumber senyawa bioaktif juga berpotensi menjadi habitat bagi bakteri endofit yang menghasilkan senyawa antimikroba. Penelitian ini bertujuan untuk mengkarakterisasi bakteri endofit dari tanaman herbal serta mengevaluasi aktivitas antibakterinya terhadap mikroorganisme patogen manusia. Penelitian menggunakan metode isolasi bakteri endofit dari jaringan tanaman herbal, diikuti dengan uji aktivitas antibakteri menggunakan metode difusi cakram terhadap bakteri patogen seperti Staphylococcus aureus dan Escherichia coli. Hasil penelitian menunjukkan bahwa beberapa isolat bakteri endofit mampu menghambat pertumbuhan bakteri patogen dengan zona hambat berkisar antara 10–18 mm. Hal ini menunjukkan bahwa bakteri endofit tanaman herbal memiliki potensi sebagai sumber senyawa antibakteri alami. Kata Kunci: Bakteri Endofit, Tanaman Herbal, Antibakteri, Mikroorganisme Patogen
Utilization of Herbal Medicines as Alternative Hypertension Therapy: A Review of Effectiveness and Safety Rifqi Ferry Balfas; Meilisa Carlen Mainassy; Desi Sri Rejeki; Lailiana Garna Nurhidayati
International Journal of Health Sciences Vol. 3 No. 4 (2025): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v3i4.887

Abstract

Hypertension remains a leading cause of global morbidity and mortality, contributing to an increased risk of coronary heart disease, kidney failure, and stroke. Conventional hypertension treatment using synthetic drugs is effective in lowering blood pressure, but often causes side effects such as dizziness, dry cough, hypokalemia, and metabolic disorders that can reduce patient compliance with therapy. Therefore, people are starting to turn to complementary and alternative treatments based on herbal plants. This study aims to review the effectiveness and safety of using herbal medicines as an alternative therapy for hypertension based on the latest scientific evidence. The research method used is systematic review. literature review of 35 scientific articles from the database PubMed, ScienceDirect, and Garuda Dikti during the period 2015–2024. The results of the study showed that plants such as garlic (Allium sativum), celery (Apium graveolens), soursop leaves (Annona muricata), and pegagan (Centella asiatica) has the effect of lowering blood pressure through the mechanism of vasodilation, increasing the production of nitric oxide oxide , diuretic effects, and antioxidant activity. Although most studies show positive results, most of the trials are still preclinical and require confirmation through large-scale clinical trials. In conclusion, herbal medicines have the potential to be used as complementary therapies for hypertension with minimal side effects. However, their use must be monitored by medical personnel to avoid interactions with synthetic antihypertensive drugs.
Efektivitas Agen Imunomodulator Dalam Modulasi Respons Imun Pada Pasien Penyakit Autoimun Meillisa Carlen Mainassy; Rezqiqah Aulia Rahmat
Barongko: Jurnal Ilmu Kesehatan Vol 5 No 1 (2026): Barongko : Jurnal Ilmu Kesehatan (November)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v5i1.1424

Abstract

Latar Belakang: Penyakit autoimun merupakan kelompok penyakit kronis yang ditandai oleh hilangnya toleransi imun terhadap antigen tubuh sendiri sehingga menyebabkan inflamasi kronis dan kerusakan jaringan. Diperkirakan lebih dari 80 jenis penyakit autoimun telah diidentifikasi, termasuk rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, psoriasis, inflammatory bowel disease, dan autoimmune thyroid disease. Perkembangan terapi imunomodulator telah mengubah tata laksana penyakit autoimun melalui pengendalian aktivitas sistem imun tanpa menyebabkan imunosupresi total. Tujuan: Menganalisis efektivitas agen imunomodulator dalam memodulasi respons imun pada pasien penyakit autoimun berdasarkan bukti ilmiah terkini. Metode: Penelitian menggunakan metode Systematic Literature Review sesuai pedoman PRISMA 2020. Artikel dicari melalui PubMed, Scopus, Web of Science, Embase, dan Cochrane Library dengan rentang publikasi 2020–2025. Kualitas artikel dinilai menggunakan Joanna Briggs Institute Critical Appraisal Tools, sedangkan risiko bias dievaluasi menggunakan RoB 2 dan ROBINS-I. Hasil: Sebanyak 27 artikel memenuhi kriteria inklusi. Agen biologik seperti inhibitor TNF-α, inhibitor IL-6, inhibitor IL-17, inhibitor IL-23, rituximab, abatacept, dan inhibitor JAK menunjukkan efektivitas yang tinggi dalam menurunkan aktivitas penyakit, kadar sitokin proinflamasi, autoantibodi, serta biomarker inflamasi. Terapi biologik juga meningkatkan kualitas hidup dan menurunkan angka kekambuhan dibandingkan terapi konvensional. Kesimpulan: Agen imunomodulator modern memberikan manfaat yang signifikan dalam mengendalikan penyakit autoimun melalui modulasi berbagai jalur imun. Pemilihan terapi perlu disesuaikan dengan karakteristik penyakit, profil imunologis pasien, keamanan, dan risiko efek samping.
Sosialisasi Optimalisasi Pangan Lokal untuk Pangan Fungsional di SMP Negeri 5 Ambon Meillisa Carlen Mainassy; Cecilia Ana Seumahu; Deford Cristy Birahy; Indah Baharudin; Christo Putra Yehuda Likumahwa
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 6, No 2 (2026): Abdira, April
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v6i2.1792

Abstract

Local food has great potential as a source of functional food that plays a role in improving health quality and supporting regional food security. However, students' understanding of healthy food and the use of local food is still limited. This community service activity aims to increase the knowledge and awareness of students at SMP Negeri 5 Ambon regarding the optimization of local food as functional food, as well as encourage the formation of positive attitudes towards local food consumption. The methods used included educational and participatory socialization, and evaluation. The results of the activity showed that before the socialization, only about 30% of students were able to explain the concept of healthy food in general and less than 25% knew the function of local food as functional food. After the activity, students' understanding increased, as indicated by approximately 80% of students being able to explain the concept of functional food simply and 75% being able to identify examples of local food that have health benefits. In addition, approximately 70% of students were actively involved in discussions related to daily food consumption habits. This activity is expected to raise students' awareness to utilize local food as a healthy and nutritious alternative.
Kampung Sadar Obat: Pemberdayaan Masyarakat Dalam Mewujudkan Pengelolaan Obat Rumah Tangga Yang Aman: Drug-Aware Village: Community Empowerment to Ensure Safe Household Medication Management Rahmat Pannyiwi; Rezqiqah Aulia Rahmat; Meillisa Carlen Mainassy
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 4 No. 4 (2026): Sahabat Sosial: Jurnal Pengabdian Masyarakat (September)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v4i4.1652

Abstract

Latar Belakang: Obat merupakan salah satu komponen penting dalam pemeliharaan dan peningkatan kesehatan masyarakat. Penggunaan obat yang tepat dapat memberikan manfaat optimal, sedangkan penggunaan yang tidak sesuai dapat menimbulkan risiko seperti kesalahan penggunaan, efek samping, interaksi obat, dan masalah akibat penyimpanan maupun pembuangan obat yang tidak tepat. Dalam lingkungan rumah tangga, masih ditemukan berbagai permasalahan seperti penyimpanan obat tanpa memperhatikan kondisi yang dipersyaratkan, penggunaan obat berdasarkan pengalaman sebelumnya, ketidaktepatan membaca informasi pada kemasan, serta pembuangan obat yang tidak sesuai. Pemberdayaan masyarakat melalui program Kampung Sadar Obat diperlukan untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam mengelola obat secara aman. Tujuan: Meningkatkan pengetahuan dan keterampilan masyarakat dalam memperoleh, menggunakan, menyimpan, dan membuang obat rumah tangga secara tepat dan aman. Metode: Kegiatan Pengabdian kepada Masyarakat dilaksanakan pada masyarakat umum di lingkungan komunitas kampung dengan jumlah peserta sebanyak 30 orang. Metode kegiatan meliputi penyuluhan kesehatan, edukasi penggunaan obat yang rasional, diskusi interaktif, pelatihan pengelolaan obat rumah tangga, pendampingan, dan evaluasi pretest–posttest. Materi mencakup prinsip penggunaan obat yang tepat, membaca label dan etiket, mengenali tanggal kedaluwarsa, penyimpanan obat, penggunaan obat bebas dan bebas terbatas secara bijak, kepatuhan terhadap aturan penggunaan obat, pengenalan tanda obat rusak, serta pengelolaan dan pembuangan obat yang sudah tidak digunakan. Hasil: Terjadi peningkatan pengetahuan masyarakat setelah mengikuti kegiatan. Rerata skor pengetahuan meningkat dari 60,8 sebelum kegiatan menjadi 87,2 setelah kegiatan. Peningkatan pemahaman terutama terlihat pada kemampuan membaca label dan etiket obat, mengenali tanggal kedaluwarsa, menentukan kondisi penyimpanan, serta memahami prinsip pembuangan obat yang sudah tidak digunakan. Peserta juga menunjukkan peningkatan kemampuan dalam mengidentifikasi praktik pengelolaan obat yang tidak aman di lingkungan rumah tangga. Kesimpulan: Program Kampung Sadar Obat melalui edukasi dan pemberdayaan masyarakat dapat meningkatkan pengetahuan serta keterampilan dalam pengelolaan obat rumah tangga yang aman. Keberlanjutan kegiatan diperlukan melalui pendampingan dan edukasi berkala dengan melibatkan tenaga kefarmasian, kader kesehatan, dan unsur masyarakat.
Co-Authors Agus Oman Sudrajat Aji, Sulistyani Prabu Andri Yanto Andriyanto Andriyanto Andriyanto Anik Nuryati, Anik Apricilda Olivia Latusallo2 Aryadi, Anggi Asbath Said Asinado Hutabalian1 Baharudin, Indah Bambang Gunadi Bambang Gunadi Bambang Gunadi Birahy, Deford Cristy Cecilia Ana Seumahu Chomsa Dintasari Umi Baszary Christo Putra Yehuda Likumahwa Deford Cristy Birahy Desi Sri Rejeki Dewi Parwati Dewi, Chitra Edi Pramono Eka Afrika Eni Kurniati Erika Erika Ervan, Ervan Febriyanti1 Gainau, Paskanova Christi Ganoko, Marwan Ahmad Glory Gelarich Simanjuntak Glory Gelarich Simanjuntak Harlina Harlina Harnia Harnia Harnia Hilal, Achmad Hondor Saragih Indah Baharudin Jacob L.A. Uktolseja juwariah, siti Kamaruddin, Muh. Ihsan Kapelle, Imanuel B. D. Karlina Angga Pradhita Kasmara, Dwi Pratiwi Lailiana Garna Nurhidayati Latif, Farida Latif, Sarifudin Andi Madellayne Glosallya Ririmasse Martanto Martosupono Maulida Isna Latifah MAURITZ PANDAPOTAN MARPAUNG Meylany Songjanan Muhamad Risal Tawil Musaidah Musaidah Nawangwulan, Kurniati Ningsih, Warti Novi Novi Nur Aida Kubangun * Nurani Hasanela2 Nurhaedah Nurhaedah Nursinah, Andi Olivia Fresley Rumyaan2 P, Nur Triningtias Pannyiwi, Rahmat Petra Willem Rodnels Melatunan Putri, Noviyanti Rahardjo Putu Ayu Sri Astuti Suka Rahmat Pannyiwi Rahmat Pannyiwi Rahmat Pannyiwi Rahmat, Rezqiqah Aulia Reffita, Lea Ingne Restiyanti, Yuli Rezqiqah Aulia Rahmat Riauwati, Juli Rifqi Ferry Balfas Ruben, Sethiana Dewi Rukmi Juwita Safridha Kemala Putri Sary Shandy Satria Eureka Nurseskasatmata Shabrina Shalsabiela Azhar Sitti Fatimah Suabey, Suningsih Sudirman Sulfiani, Sulfiani Syaila Rizky Amanda Tandiola, Rosdiana Tondok, Santalia Banne Tuhumena, Femi Serly Ula, Zumrotul Waas, Alsye Wasmen Manalu Wijayanti, Lumastari Ajeng Yusfik, Yusnita