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Journal : science midwifery

Effectiveness Of Use Of Antihypertensive Drug In Inpatient Stroke Patients In Hospital Tabanan Regency Ni Nyoman Wahyu Udayani; Ni Luh Putu Dewi Purnama Sari
Science Midwifery Vol 10 No 2 (2022): April: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

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Abstract

Cardiovascular disease is a disease of the heart and blood vessels. Because the cardiovascular system is very vital, cardiovascular disease is very dangerous for health. One of the cardiovascular diseases is a stroke. The prevalence of stroke in Indonesia reaches 8.3 out of 1000 populations. This prevalence rate increases with increasing age. Indonesian National Data shows that stroke is the highest cause of death, which is 15.4%. Blood pressure management is a strategy to prevent stroke and reduce the risk of recurrence in ischemic stroke and hemorrhagic stroke. The purpose of this study was to determine the effectiveness of the use of antihypertensive drugs in patients with ischemic and hemorrhagic stroke inpatient care at hospital Tabanan seen from the patient's blood pressure. This research is a type of descriptive research with data collection carried out retrospectively. This study was conducted on 53 patients with ischemic stroke and hemorrhagic stroke using antihypertensive drugs. The results of the study on the effectiveness of the use of blood pressure-based antihypertensive drugs in ischemic stroke decreased systolic blood pressure by ≤5 mmHg by 8 patients (15.09%), decreased systolic blood pressure> 5 mmHg by 1 patient (1.89%). In hemorrhagic stroke decreased systolic blood pressure ≤ 5 mmHg as many as 25 patients (47.17%), decreased systolic blood pressure> 5 mmHg as many as 11 patients (20.76%) and in patients who experienced an increase in blood pressure occurred as many as 8 patients (15,09%).
Antioxidant Activity of Ethanol and Methanol Extracts of Black Turmeric (Curcuma Caesia Roxb.) Using the DPPH (2,2-Diphenyl-1-Picrylhidrazyl) Method Ni nyoman wahyu udayani; Ketut Agus Adrianta; IGAA Kusuma Wardani
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.990

Abstract

Free radicals are highly reactive compounds in the body that can cause degenerative diseases. One mechanism that can counteract free radicals is antioxidants. Natural antioxidants can be obtained from traditional drinks made from plants that contain active antioxidant compounds such as black turmeric (Curcuma caesia Roxb.) from the Zingiberaceae family. This study aims to determine the antioxidant activity of black turmeric extract. Before testing the antioxidant activity, qualitative and quantitative analysis were carried out. Qualitative analysis was carried out by phytochemical screening. The antioxidant activity of black turmeric extract was tested using the DPPH method. This test begins with the manufacture of extracts and preparation of test samples, then measurement of free radical scavenging activity using a UV-Vis spectrophotometer is carried out. Based on the results of the percentage measurement, the linear regression equation for the ethanol extract was obtained, namely y = 0.1526x + 0.9105 and the value of R2 = 0.9965, and for the methanol extract, namely y = 0.2376x + 1.6809 and the value of R2 = 0.996. According to the linear regression equation, black turmeric extract has antioxidant activity, which is categorized as a very weak antioxidant with an IC50 of 321,687 ppm for ethanol extract and 203, 363 ppm for methanol extract.
Co-Authors Adnyani, Putu Mesi Dian Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Agustin, Ni Kadek Jessica Anggreni, Ayu Putu Puspa Anita Dewi, Ni Luh Kade Arman Apriani, Rista Ariani, Komang Ciptawati, Ni Wayan Cokorda Javandira Debby Juliadi Dewi, Ni Kadek Dhea Cipta Dewi, Putu Intan Candra Dwipayanti, Ni Kadek Sari Erna Cahyaningsih Febryna Dharma Yanti, Ni Luh Putu Fitria Megawati Fredinan Yulianda Fridayana, Ni Luh Gede Erica Herleeyana Meriyani I Dewa Ayu Anom Yustari Nida I Gede Made Suradnyana I Gede Yodhi Trismawan I Gusti Agung Ayu Kusuma Wardhani I Gusti Ayu Arya Ditha Suari I Ketut Sumantra I Made Agus Sunadi Putra I Made Arendya Sumerta I Nyoman Gede Tri Sutrisna I Putu Aldy Mahendra I Putu Aldy Mahendra I Putu Pasek Jaya Separsa I Putu Tangkas Suwantara I Putu Werda Bisama I WAYAN SUDIARSA I Wayan Sudiarsa I Wayan Surya Rahadi Ida Ayu Gede Syntya Mahayani IGAA Kusuma Wardani Kadek Abdi Saputra Kadek Ayu Puspa Pratiwi Ketut Agus Adrianta Komang Ariani Laksmi, Luh Putri Dianti Lestari, Ketut Sita Citra Lilis Adnyani Ni Putu Luh Putu Febryana L Lusi Puspitasari, Ni Wayan Made Dwik Lestari Maharani, Ade Dwi Karisma Mahardika, I Made Agus Mahendra, I Putu Aldy Manik Suka Dewi Yani Ni Komang Maria Daniela Tupa Hokor Maria Malida Vernandes Sasadara Mayun Anak Agung Istri Mega Ratnasari, Ni Luh Ayu Megawati, Fitri Megawati, Fitria Meika, Ni Putu Trisna Mendra, Ni Nyoman Yudianti Meriana Barreto Amaral Nggaba, Ellenoire Rambu Kabeba Hammu Ni Kadek Ari Widiastuti Ni Kadek Ganis Wulandari Ni Kadek Ria Ariska Sari Ni Komang Ary Agustina Berliana Putri Ni Komang Enny Wahyuni Ni Luh Ayu Mega Ratnasari Ni Luh Kade Arman Anita Dewi Ni Luh Kade Arman Anita Dewi Ni Luh Putu Dewi Purnama Sari Ni Luh Putu Sulasmini Ni Luh Putu Tris Yoga Cahyani Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Neva Jayanti Ni Made Nopita Wati Ni Made Sukma Sanjiwani Ni Made Sukma Sanjiwani Ni Made Sukma Sanjiwani Ni Nyoman Ayu Puspita Sari Ni Putu Agustini Ari Dewi NI PUTU AYU MIRAH MARIATI Ni Putu Leona Yorita Dewi Ni Putu Lilis Adnyani Ni Putu Lilis Adnyani Ni Putu Putri Cahya Anggreni Ni Putu Refina Dharma Yanti Ni Putu Ria Agusthya Arya Wirdana Ni Putu Sintia Rahayu Ni Putu Trisna Meika Ni Wayan Ciptawati Ni Wayan Riastini Ni Wayan Rustiarini Nindya Kartika, Dewa Ayu Kintan Nugraha, Nyoman Dhamapada Nyoman Budiartha Siada Nyoman Utari Vipriyanti Pendet, Ni Made Diah Pusparini Puguh Santoso Puguh Santoso puguh santoso, puguh Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putri, Ni Komang Ary Agustina Berliana Putu Era Sandhi K.Yuda Putu Era Sandhi Kusuma Yuda Putu Mesi Dian Adnyani Rahadi, I Wayan Surya Riastini, Ni Wayan Siluh Putu Astini Sugijanto, Milyadi Wardani, I Gusti Agung Ayu Kusuma Wati, Ni Made Nopita Widiasriani, Ida Ayu Putu Wiguna, I Putu Bagus Artha Wiguna, Putu Dony Saputra Woro Enjang Santi Prihatin Wulandari, Ni Kadek Ganis Yowani, Anak Agung Sagung Iswarani Yustari Nida, I Dewa Ayu Anom Yuwono, Moch.