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Journal : MEDISAINS

Potential of turmeric cream (curcuma caesia roxb.) extract in incision wounds Udayani, Ni Nyoman Wahyu; Adrianta, I Ketut Agus; Wiguna, I Putu Bagus Artha; Yowani, Anak Agung Sagung Iswarani
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23731

Abstract

Background: Incisional wounds are the most common wounds in the community. Improper handling of incision wounds can worsen wounds and cause infection. The content of secondary metabolites in black turmeric rhizomes can act as anti-inflammatory and antimicrobial in the healing process of incision wounds. However, its effectiveness in healing incision wounds has not been widely studied, so further research is needed.Purpose: This study was conducted to determine the potential of black turmeric cream as an herbal medicine to heal incision wounds.Methods: This study was an invivo experimental research study with a randomized post-test control group design. The samples used were 20 male rats that were made to have a 2 cm incision wound on the back area, consisting of a negative control, a positive control, and three black turmeric extract groups (5%, 10%, and 15%). The data obtained were analyzed by an ANOVA (Analysis of Variance) parametric statistical test.Result: The results showed that the highest decrease in incision wound length was found in the black turmeric rhizome cream Formula III group and the lowest in the negative control group. On day 14, the incision wound area of the Formula III black turmeric rhizome cream group had closed or healed (0.00 cm), while the negative control group had the slowest incision wound closure (0.39 cm).Conclusion: Black turmeric rhizome cream can heal and prevent infection of the incision wound. This shows the potential of black turmeric rhizome as an anti-inflammatory and antimicrobial.
Potential of turmeric cream (curcuma caesia roxb.) extract in incision wounds Udayani, Ni Nyoman Wahyu; Adrianta, I Ketut Agus; Wiguna, I Putu Bagus Artha; Yowani, Anak Agung Sagung Iswarani
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23731

Abstract

Background: Incisional wounds are the most common wounds in the community. Improper handling of incision wounds can worsen wounds and cause infection. The content of secondary metabolites in black turmeric rhizomes can act as anti-inflammatory and antimicrobial in the healing process of incision wounds. However, its effectiveness in healing incision wounds has not been widely studied, so further research is needed.Purpose: This study was conducted to determine the potential of black turmeric cream as an herbal medicine to heal incision wounds.Methods: This study was an invivo experimental research study with a randomized post-test control group design. The samples used were 20 male rats that were made to have a 2 cm incision wound on the back area, consisting of a negative control, a positive control, and three black turmeric extract groups (5%, 10%, and 15%). The data obtained were analyzed by an ANOVA (Analysis of Variance) parametric statistical test.Result: The results showed that the highest decrease in incision wound length was found in the black turmeric rhizome cream Formula III group and the lowest in the negative control group. On day 14, the incision wound area of the Formula III black turmeric rhizome cream group had closed or healed (0.00 cm), while the negative control group had the slowest incision wound closure (0.39 cm).Conclusion: Black turmeric rhizome cream can heal and prevent infection of the incision wound. This shows the potential of black turmeric rhizome as an anti-inflammatory and antimicrobial.
Co-Authors Adnyani, Putu Mesi Dian Adrianta, I Ketut Agus Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Agustin, Ni Kadek Jessica Agustini, Ni Putu Dewi Anggreni, Ayu Putu Puspa Anita Dewi, Ni Luh Kade Arman Apriani, Rista Ciptawati, Ni Wayan Cokorda Javandira Debby Juliadi Dewi, Ni Kadek Dhea Cipta Dewi, Putu Intan Candra Dwipayanti, Ni Kadek Sari Erna Cahyaningsih Febryna Dharma Yanti, Ni Luh Putu Fitria Megawati Fitria Megawati Fredinan Yulianda Fridayana, Ni Luh Gede Erica Herleeyana Meriyani Herleeyana Meriyani I Dewa Ayu Anom Yustari Nida I Gede Made Suradnyana I Gede Yodhi Trismawan I Gusti Agung Ayu Kusuma Wardhani I Gusti Ayu Arya Ditha Suari I Ketut Sumantra I Made Agus Sunadi Putra I Made Agus Sunadi Putra I Made Agus Sunadi Putra I Made Agus Sunadi Putra I Nyoman Gede Tri Sutrisna I Putu Pasek Jaya Separsa I Putu Tangkas Suwantara I Putu Werda Bisama Ida Ayu Gede Syntya Mahayani IGAA Kusuma Wardani Kadek Ayu Puspa Pratiwi Ketut Agus Adrianta Ketut Agus Adrianta Ketut Agus Adrianta Ketut Agus Adrianta Ketut Agus Adrianta Ketut Agus Adrianta Ketut Agus Adrianta Laksmi, Luh Putri Dianti Lestari, Ketut Sita Citra Lilis Adnyani Ni Putu Luh Putu Febryana L Lusi Puspitasari, Ni Wayan Made Dwik Lestari Maharani, Ade Dwi Karisma Mahardika, I Made Agus Mahendra, I Putu Aldy Manik Suka Dewi Yani Ni Komang Maria Daniela Tupa Hokor Maria Malida Vernandes Sasadara Mayun Anak Agung Istri Mega Ratnasari, Ni Luh Ayu Megawati, Fitri Megawati, Fitria Meika, Ni Putu Trisna Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Nggaba, Ellenoire Rambu Kabeba Hammu Ni Komang Enny Wahyuni Ni Luh Ayu Mega Ratnasari Ni Luh Kade Arman Anita Dewi Ni Luh Kade Arman Anita Dewi Ni Luh Putu Dewi Purnama Sari Ni Luh Putu Sulasmini Ni Luh Putu Tris Yoga Cahyani Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Sukma Sanjiwani Ni Nyoman Ayu Puspita Sari Ni Putu Dewi Agustini Ni Putu Leona Yorita Dewi Ni Putu Lilis Adnyani Ni Putu Lilis Adnyani Ni Putu Putri Cahya Anggreni Ni Putu Refina Dharma Yanti Ni Putu Sintia Rahayu Ni Wayan Ciptawati Ni Wayan Riastini Nindya Kartika, Dewa Ayu Kintan Nugraha, Nyoman Dhamapada Nyoman Budiartha Siada Pendet, Ni Made Diah Pusparini Puguh Santoso Puguh Santoso puguh santoso, puguh Putra Hilmi Prayitno Putra, I Made Agus Sunadi Putri, Ni Komang Ary Agustina Berliana Putu Era Sandhi K.Yuda Putu Era Sandhi Kusuma Yuda Putu Mesi Dian Adnyani Riastini, Ni Wayan Sasadara, Maria Malida Vernandes Siluh Putu Astini Sugijanto, Milyadi Sunadi Putra I Made Agus Wardani, I Gusti Agung Ayu Kusuma Widiasriani, Ida Ayu Putu Wiguna, I Putu Bagus Artha Wiguna, Putu Dony Saputra Woro Enjang Santi Prihatin Wulandari, Ni Kadek Ganis Yowani, Anak Agung Sagung Iswarani Yustari Nida, I Dewa Ayu Anom Yuwono, Moch.