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All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Jurnal Media Gizi Indonesia (MGI) The Indonesian Journal of Public Health Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Amerta Nutrition Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Jurnal Kesehatan Tambusai Makara Journal of Health Research Journal of Medicine and Health Jurnal Widya Medika Preventif : Jurnal Kesehatan Masyarakat
Bambang Wirjatmadi
Department Of Nutrition, Faculty Of Public Health, Universitas Airlangga, Surabaya, Indonesia ; Department Of Clinical Nutrition, Airlangga University Hospital, Surabaya, Indonesia & Department Of Clinical Nutrition, PHC Hospital, Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Health Notions

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Cocoa Liquor Increases SOD Activity in Wistar Rats Experiencing Oxidative Stress Dwi Putra, Kartika Wahyu; Wirjatmadi, Bambang; Purwanto, Bambang; Adriani, Merryana
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Young Khalaal Dates (Phoenix dactylifera) Effect on Blood Glucose in Alloxan-induced Wistar Male Rats Sholikhah, Desty Muzarofatus; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Young Khalaal Dates (Phoenix dactylifera) Effect on Blood Glucose in Alloxan-induced Wistar Male Rats
Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Rahayu, Aprilia Nurcahyaning; Wirjatmadi, Bambang; Adriani, Merryana; M., Soenarnatalina; Winarni, Dwi; Hartiningsih, Sri
Health Notions Vol 2 No 1 (2018): January, 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Influence of Cinnamon Extract (Cinnamomum burmanii) Provision on the Reduction of Blood Glucose Level of Hyperglycemic Male Wistar Rats Aulia, Kharina; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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The number of patients with hyperglycemia in the world and in Indonesia is estimated to increase rapidly in the next 25 years. The content of cinnamaldehyde, flavonoids, polyphenols, and chromium in cinnamon thought to have an influence of hypoglycemia. This study aimed to determine the influence of cinnamon extract to a decrease of blood glucose levels in hyperglycemic rats induced by a single dose of alloxan as much as 125 mg/kg. This study was laboratory experiment by using RAL (Complete Randomize Design) with Pre-Post Test Control Group Design Research. Experimental animals used were male Wistar rats divided into 5 groups. KN was negative control group. KP was hyperglycemic positive control group. P1 was the first treatment group (a dose of 200 mg/kg). P2 was the second treatment group (a dose of 250 mg/kg). P3 was the third treatment group (a dose of 300 mg/kg). Cinnamon therapy was given orally for 14 days. The results of this research was tested statistically by using One Way ANOVA and showed that there were significant differences between the blood glucose levels in the treatment group with the positive and negative control groups. The conclusion was that the provision of cinnamon extract for 14 days could provide an influence of lowering blood glucose levels.  Keywords: Blood glucose, Cinnamon, Hyperglicemia
Effects of Purple Sweet Potatoes on Oxidative Stress Biomarkers in Rats Subjected to Exhaustive Exercise Sholikhah, Anindya Maratus`; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 2 (2018): February 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Oxidative stress is a condition caused by the imbalance between the production of free radicals or ROS and the antioxidants; the level of free radicals is higher than the antioxidants. Exhaustive exercise is one of the causes of this oxidative stress. However, it can be reduced by antioxidants found in purple sweet potatoes (PSP) (Ipomoea batatas L). This study aims to evaluate the effect of two weeks supplementation of PSP extract on rats inducedoxidative stress. Twenty rats were distibuted into four groups consisted five rats each. Rats in the treatments groups were administered PSP extract for two weeks then were forced to swim until exhausted. Bloods from all samples were drawn to see the changes in the levels of malondialdehyde ans superoxide dismutase after two weeks of treatment. The data was then analyzed using descriptive and inferential statistic. The results showed that mean level of MDA and SOD differ significantly (p<0.05) between groups after the administration of PSP extract as well as after exhaustive exercise. The extracts and exhaustive exercise concurrently showed a significant effect on oxidative stress biomarkers (p<0.05). It concluded that PSP extract can protect cells against free radical produced by exhaustive exercise. 
The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females Astuti, Nanik Dwi; Wirjatmadi, Bambang; Adriani, Merryana
Health Notions Vol 2 No 3 (2018): March 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Prevention of iron deficiency anemia in Indonesia using ferrous sulfas blood-added tablets started since 1997. But iron deficiency anemia is still high, also in young women. Young women are vulnerable because of rapid growth and unhealthy their consumption patterns, which rarely consume fruits and vegetables that are a source of vitamin C. The purpose of this study was to analyze the addition of vitamin C in iron supplementation + folic acid to serum ferritin levels in adolescents females anemia. This research was an experimental quasi research. Design of research was Randomized Pre Post Test Control Group Design, with Double Blind treatment. This study had one treatment group and one control group, each group of 11 samples. The samples were chosen randomly with inclusion and exclusion. The collected data was processed using SPSS program with the analysis of paired t-test and independent t-test to test the difference of serum ferritin level. The results was showed the characteristics of respondents: age (p = 0.430), education of mother (p = 0.942) and nutritional knowledge of respondents (p = 0.928) in the same condition or both groups were had homogeneous characteristics. The pattern and level of food consumption were showed no different between control and traetment groups (p> 0.05). Serum ferritin levels showed difference between the two groups after treatment (p = 0.004). The study was showed vitamin C had role in increasing iron absorption and fill in storage of ferritin formation. Keywords: Anemia, Vitamin C, Iron supplement, Ferritin
Green Tea (EGCG) Decreases Malondialdehide In Oxidative Stress Exposure To Psychological Stress Priaminda, M Dodi F; Wirjatmadi, Bambang; Purwanto, Bambang; Adriani, Merryana
Health Notions Vol 2 No 7 (2018): July 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Expression of VCAM in Male Wistar Rats (Rattus norvegicus) with Hypercholesterolemia Supplemented with Pumpkin Seeds (Cucurbita moschata Duch) Extract Proboningsih, Jujuk; Wirjatmadi, Bambang; Kuntoro, Kuntoro; Adriani, Merryana
Health Notions Vol 2 No 6 (2018): June 2018
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Treatment of cardiovascular diseases tends to be expensive and requires long-term therapy. Investigation about the effect of pumpkin seeds on prevention of endothelial dysfunction of blood vessel has never been reported yet, accordingly, bodies of research are required to know its effectiveness. This study aimed to analyze the expression of Vascular Cell Adhesion Molecule (VCAM) in male Wistar rats (Rattus norvegicus) with hypercholesterolemia supplemented with pumpkin seeds extract (Cucurbita moschata Duch). This was an experimental laboratory study with randomized post-test control group design. The independent variable was pumpkin seeds extract, and the dependent one was expression of VCAM. Data analysis employed chi-square test to test the difference between control and treatment groups. Study results showed that there was significant difference (p=0.000) between VCAM expression in group-K2 (positive control) as compared to group-K1 (negative control) and group-K5 (treatment group-dose 3) α=0.001, whereas no significant difference was found between that of as compared to group-K3 (treatment group-dose 1) α=0.125 and group-K4 (treatment group-dose 2) α=0.05. The study showed reduction of VCAM expression in treatment groups consisted of male Wistar rats with hypercholesterolemia supplemented with pumpkin seeds (Cucurbita moschata Duch) extract. Keywords: Pumpkin seeds, VCAM expression, hypercholesterolemia
The Role of Nutritional Status, Dietary Pattern, and Free Radical in the Insulin Resistance Development Sari, Meirna Dewita; Wirjatmadi, R. Bambang; Adriani, Merryana
Health Notions Vol 1 No 4 (2017): October-December 2017
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Insulin resistance is an early sign of diabetes type 2 that occurs in situations where target organ sensitivity decreases against insulin. Excess free radicals can be mutually insulin resistance. The purpose of this study was to determine how the effects of insulin can be a determining factor. This study used case control design conducted on 22 outpatients at Clinic University of Muhammadiyah Surabaya during June until July 2017. Data were collected using questionnaires, nutritional status, fasting blood glucose, fasting insulin, and MDA levels. Insulin resistance status using normal HOMA IR method of <2,77. Logistic Regression was used to determine the effect of free radical on the occurrence of insulin resistance. The results showed free radical against insulin resistance at a=0,05 with p=0,018. That result means boosting MDA levels also increases the risk of insulin resistance. In addition, the consumption of dietary sources of fat and excessive use of food additives, low fruit intake, BMI values are also factors affecting insulin resistance with p=0,027; p=0,036; and p=0,027. Given the elevated levels of MDA-free radicals can increase the risk of insulin resistance. Applying a healthy lifestyle by consuming fiber-rich foods can prevent the formation of excessive free radicals. Keywords: Insulin Resistance, Free Radical, HOMA IR
Robusta Coffee Decreased Malondialdehyde Levels in Wistar Mice Experiencing Oxidative Stress Abidah, Rahmi Syarifatun; Wirjatmadi, Bambang; Purwanto, Bambang; Adriani, Merryana
Health Notions Vol 1 No 4 (2017): October-December 2017
Publisher : Humanistic Network for Science and Technology (Address: Cemara street 25, Ds/Kec Sukorejo, Ponorogo, East Java, Indonesia 63453)

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Abstract

Coffee drinking is a habit that still doubtful for it’s benefits. Many active ingredients in robusta coffee (Coffea canephora) are very useful for health, especially the antioxidant content that can ward off free radicals that absorbed in the body. Free radicals can be caused by psychological stress exposure. Excessive amounts of radicals in the body cause oxidative stress. This study aimed to see the robusta coffee effect on decreasing levels of Malondialdehyde (MDA) with “randomized post test only control group” design with 25 samples of white male rat strain wistar (Rattus norvegicus). Samples were divided into 5 groups: control groups and randomized treatment groups. Treatment given in psychological stress and giving robusta coffee drink with single dose. This study used “one way anova” test and followed by “pos hoc tukey HSD” test for statistics. Robusta coffee had an effect in MDA levels changing. There was a MDA levels decreasing in 1 hour after robusta coffee drinking in experimental rats with oxidative stress conditions that were exposed by psychological stress.   
Co-Authors Ade Saputra Nasution Adriani, Meriyana Adriani, Merriyana Ahmad Nur Huda AMBARWATI, SEPTIANA Amelia Dyah Kartika Sari Anak Agung Gede Sugianthara Andriani, Merryana Anindya Mar’atus Sholikhah Anisah Khoirul Umah Annisa Rizka Oktavianita Aprilia Nurcahyaning Rahayu Arinda Lironika Suryana Arwati, Niluh Astuti, Nanik Dwi Aulia, Kharina Auliannisaa, Alifia Ayuningtyas, Septiadeti Hidayati Bambang Purwanto Bambang Purwanto Bambang Purwanto Cindy Claudia Nurulita Civana Dea Alnanda Cut Athira Sauma D.A. Liona Dewi Damayanti, Adelina Elsa Desy Prasetya, Desy Diana Rizqi Fauziyah Dini Setiarsih Dwi Putra, Kartika Wahyu Dwi Winarni Eganda Garwahusada Emi Nur Cholidah Erliza Anggraini Firdaus Etha Rambung Fara Disa Durry Fatifa Asmarani, Fatifa Hadiar Huriyah Rahma Haqqelni Nur Rosyidah Harisma Harisma Himaya Himaya Ikanov Safitri INDROPO AGUSNI Isaura, Emyr Reisha Jayanthi Petronela Janggu Jujuk Proboningsih, Jujuk Kadek Tresna Adhi Kartika Indaswari Dewi Kartika Wahyu Dwi Putra Kharina Aulia Khoiroh, Ummul Kirana, Dhea Sukma Kuntoro Kuntoro Kuntoro Kuntoro Kurniasari, Nadya Putri Kusuma, Anindita M. Dodi F Priaminda M., Soenarnatalina Mangestuti Agil Maria Widijanti Sugeng Meirna Dewita Sari Merryana Adriani Merryana Adriyani Merryana Andriani Merryna Adriani Minarni Wartiningsih Mohammad Z. Rahfiludin Nabilla Siti Hawa Fatimah Nanik Dwi Astuti Novera Herdiani, Novera Novita Eka Hardini Nur Nashriana Jufri Nuraini, Sekarsari Oktovina Rizky Oktovina Rizky, Oktovina Pratama, Dafa Azhari Priaminda, M Dodi F Pudji Astutik, Pudji Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah Rahmi Syarifatun Abidah, Rahmi Syarifatun Retno Larasati Retno Larasati Rifka Laily Mafaza Rina Wasesa Aprilia Lazulfa Rinda Istiqumilaily Rivan Virlando Suryadinata Sari, Yulianti Wulan Setiarsih, Dini Setyaningtyas, Stefani Widya Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina M. Soenarnatalina Meilanani Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Sri Sumarmi Stefania W Setyaningtyas Supriyadi Supriyadi Suryadinata, Rivan Virlando Susanti, Yuyun Erlina Vidya Noermalawati Vyatri Pricilya Wardani, Karmila Ayu Yoes P. Dahlan Yunita Satya Pratiwi Yuyun Erlina Susanti Zahirah, Fildza Zolla Gracia Amardiani