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All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Jurnal Media Gizi Indonesia (MGI) The Indonesian Journal of Public Health Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Amerta Nutrition Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Jurnal Kesehatan Tambusai Makara Journal of Health Research Journal of Medicine and Health Jurnal Widya Medika Preventif : Jurnal Kesehatan Masyarakat
Bambang Wirjatmadi
Department Of Nutrition, Faculty Of Public Health, Universitas Airlangga, Surabaya, Indonesia ; Department Of Clinical Nutrition, Airlangga University Hospital, Surabaya, Indonesia & Department Of Clinical Nutrition, PHC Hospital, Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Health Notions

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Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Aprilia Nurcahyaning Rahayu; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina M.; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (246.122 KB) | DOI: 10.33846/hn.v2i1.85

Abstract

Bee pollen, as an active ingredient in diabetes mellitus (DM) prevention and treatment, is able to reduce oxidative reactions and to regenerate cells. This study aimed to determine bee pollen effect on blood glucose levels of rats which induced by alloxan. This study used a completely randomized design with Pre-Post Test design and Control Group design. The subjects were 25 male wistar rats which divided randomly into 5 groups: (1) negative control group (non-DM rats); (2) positive control group (DM rats without bee pollen); (3) P1 group (DM rats with 0.25 g/day bee pollen); (4) P2 group (DM rats with 0.63 g/day bee pollen); and (5) P3 group (DM rats with 1.25 g/day bee pollen). Alloxan inducing was used to cause rats under DM or hyperglycemic conditions. The data were analyzed by Manova test and Tukey HSD test. Statistical analysis showed that bee pollen effectively had an effect on decreasing fasting blood glucose (FBG) levels in treatment groups with 0.002. Differences test showed a difference between positive control group and treatment groups, but there was no difference between all treatment groups. However, the bee pollen dosage which giving the lowest average of FBG was 0.25 g on P1 group. Keywords: Bee pollen, Blood glucose level, Alloxan
Expression of VCAM in Male Wistar Rats (Rattus norvegicus) with Hypercholesterolemia Supplemented with Pumpkin Seeds (Cucurbita moschata Duch) Extract Jujuk Proboningsih; Bambang Wirjatmadi; Kuntoro Kuntoro; Merryana Adriani
Health Notions Vol 2, No 6 (2018): June
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (970.221 KB) | DOI: 10.33846/hn.v2i6.214

Abstract

Treatment of cardiovascular diseases tends to be expensive and requires long-term therapy. Investigation about the effect of pumpkin seeds on prevention of endothelial dysfunction of blood vessel has never been reported yet, accordingly, bodies of research are required to know its effectiveness. This study aimed to analyze the expression of Vascular Cell Adhesion Molecule (VCAM) in male Wistar rats (Rattus norvegicus) with hypercholesterolemia supplemented with pumpkin seeds extract (Cucurbita moschata Duch). This was an experimental laboratory study with randomized post-test control group design. The independent variable was pumpkin seeds extract, and the dependent one was expression of VCAM. Data analysis employed chi-square test to test the difference between control and treatment groups. Study results showed that there was significant difference (p=0.000) between VCAM expression in group-K2 (positive control) as compared to group-K1 (negative control) and group-K5 (treatment group-dose 3) α=0.001, whereas no significant difference was found between that of as compared to group-K3 (treatment group-dose 1) α=0.125 and group-K4 (treatment group-dose 2) α=0.05. The study showed reduction of VCAM expression in treatment groups consisted of male Wistar rats with hypercholesterolemia supplemented with pumpkin seeds (Cucurbita moschata Duch) extract. Keywords: Pumpkin seeds, VCAM expression, hypercholesterolemia
Co-Authors Ade Saputra Nasution Adriani, Meriyana Adriani, Merriyana Ahmad Nur Huda AMBARWATI, SEPTIANA Amelia Dyah Kartika Sari Anak Agung Gede Sugianthara Andriani, Merryana Anindya Mar’atus Sholikhah Anisah Khoirul Umah Annisa Rizka Oktavianita Aprilia Nurcahyaning Rahayu Arinda Lironika Suryana Arwati, Niluh Astuti, Nanik Dwi Aulia, Kharina Auliannisaa, Alifia Ayuningtyas, Septiadeti Hidayati Bambang Purwanto Bambang Purwanto Bambang Purwanto Cindy Claudia Nurulita Civana Dea Alnanda Cut Athira Sauma D.A. Liona Dewi Damayanti, Adelina Elsa Desy Prasetya, Desy Diana Rizqi Fauziyah Dini Setiarsih Dwi Putra, Kartika Wahyu Dwi Winarni Eganda Garwahusada Emi Nur Cholidah Erliza Anggraini Firdaus Etha Rambung Fara Disa Durry Fatifa Asmarani, Fatifa Hadiar Huriyah Rahma Haqqelni Nur Rosyidah Harisma Harisma Himaya Himaya Ikanov Safitri INDROPO AGUSNI Isaura, Emyr Reisha Jayanthi Petronela Janggu Jujuk Proboningsih, Jujuk Kadek Tresna Adhi Kartika Indaswari Dewi Kartika Wahyu Dwi Putra Kharina Aulia Khoiroh, Ummul Kirana, Dhea Sukma Kuntoro Kuntoro Kuntoro Kuntoro Kurniasari, Nadya Putri Kusuma, Anindita M. Dodi F Priaminda M., Soenarnatalina Mangestuti Agil Maria Widijanti Sugeng Meirna Dewita Sari Merryana Adriani Merryana Adriyani Merryana Andriani Merryna Adriani Minarni Wartiningsih Mohammad Z. Rahfiludin Nabilla Siti Hawa Fatimah Nanik Dwi Astuti Novera Herdiani, Novera Novita Eka Hardini Nur Nashriana Jufri Nuraini, Sekarsari Oktovina Rizky Oktovina Rizky, Oktovina Pratama, Dafa Azhari Priaminda, M Dodi F Pudji Astutik, Pudji Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah Rahmi Syarifatun Abidah, Rahmi Syarifatun Retno Larasati Retno Larasati Rifka Laily Mafaza Rina Wasesa Aprilia Lazulfa Rinda Istiqumilaily Rivan Virlando Suryadinata Sari, Yulianti Wulan Setiarsih, Dini Setyaningtyas, Stefani Widya Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina M. Soenarnatalina Meilanani Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Sri Sumarmi Stefania W Setyaningtyas Supriyadi Supriyadi Suryadinata, Rivan Virlando Susanti, Yuyun Erlina Vidya Noermalawati Vyatri Pricilya Wardani, Karmila Ayu Yoes P. Dahlan Yunita Satya Pratiwi Yuyun Erlina Susanti Zahirah, Fildza Zolla Gracia Amardiani