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Skrining Paru-paru sebagai Upaya Promotif dan Preventif bagi Ibu Rumah Purwaningsih, Desi; juliana, dara; budi, ikhsan; Pratami Djasfar, Seftiwan; Putra Djonesti, wilfadri; Simanjuntak, Kristina; Yulianti, Retno
Jurnal Abdimas Mandiri Vol. 9 No. 3
Publisher : UNIVERSITAS INDO GLOBAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36982/jam.v9i3.6194

Abstract

Penyakit paru seperti penyakit paru obstruktif kronis (PPOK), tuberkulosis, dan gangguan restriktif masih menjadi masalah kesehatan masyarakat yang signifikan di Indonesia. Ibu rumah tangga merupakan kelompok yang rentan karena sering terpapar polusi udara dalam ruangan, termasuk asap dapur, asap rokok, dan pembakaran bahan bakar biomassa yang digunakan untuk memasak. Paparan jangka panjang terhadap faktor tersebut dapat menyebabkan penurunan fungsi paru yang sering kali tidak disadari karena gejalanya muncul secara perlahan. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan kesadaran, pengetahuan, serta kemampuan deteksi dini gangguan fungsi paru melalui edukasi kesehatan dan pemeriksaan spirometri pada ibu rumah tangga di Kelurahan Pondok Petir, Kota Depok. Metode pelaksanaan menggunakan pendekatan Plan–Do–Check–Act (PDCA) yang meliputi tahap perencanaan kegiatan, penyuluhan kesehatan tentang penyakit paru, demonstrasi penggunaan alat spirometri, pemeriksaan fungsi paru secara individual, serta evaluasi dan tindak lanjut hasil. Sebanyak sepuluh peserta mengikuti pemeriksaan spirometri, dengan hasil 50% mengalami restriksi ringan, 10% restriksi sedang, dan 40% tidak menunjukkan gangguan ventilasi paru. Hasil ini menunjukkan adanya indikasi awal penurunan fungsi paru yang memerlukan perhatian lebih lanjut. Kegiatan ini berhasil meningkatkan pengetahuan peserta mengenai faktor risiko penyakit paru, pentingnya ventilasi rumah, serta kebiasaan hidup sehat. Program ini mendukung penguatan upaya promotif dan preventif kesehatan pernapasan sesuai dengan kebijakan nasional Program Indonesia Sehat dengan Pendekatan Keluarga (PIS-PK).
Preparation and Characterization of P(3HB-co-HHX)/Silk Fibroin Nanofiber for Chondrogenic Differentiation on Human Adipose Mesenchymal Stem Cell Pramono, Andri Pramesyanti; Yulianti, Retno; Razi, Muhamad Alif; Karina; Ang, Shaik Ling; Sudesh, Kumar; Hanan; Endarwati, Yuni Cahya; Ghoza, Muhammad Radian
HAYATI Journal of Biosciences Vol. 33 No. 3 (2026): May 2026
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.33.3.617-633

Abstract

This study explored the proliferative and chondrogenic differentiation capacities of nanofiber containing silk fibroin hybrid Bombyx mori silkworm cocoons (Japan-China SP-01 variant from Indonesia) and PHA P(3HB-co-3HHx) on human adipose mesenchymal stem cells. First, the scaffolds were prepared for electrospinning by combining two distinct biomaterials, consisting of silk fibroin derived from hybrid Bombyx mori silkworm cocoons, with a combination of 3-hydroxybutyrate (3HB) and 3-hydroxyhexanoate (3HHx). The effects of various ratios of P(3HB-co-3HHx)/Silk Fibroin nanofiber mixture on proliferative and differentiation capacity were then investigated. Following that, the morphology, chemical compositions, contact angle, tensile strength, roughness, cell viability, and human adipose mesenchymal stem cell differentiation of the nanofiber were investigated by collagen type 2 gene expression. The results of scanning electron microscopy showed the mean diameter of the nanofiber ranged from 370-600  nm. Following that, 16,000 volts was prominent for nanofiber manufacture in all ratios. It was also demonstrated that the nanofiber has significant mechanical properties, acceptable hydrophilicity and smoothness, and appropriate cell viability (up to 99.1% compared to the control on silk fibroin nanofiber). Although PHA increased tensile strength, silk fibroin administration to the mixture predominantly enhanced chondrogenic differentiation, as evidenced by modulation of chondrogenic collagen type 2 (up to 8.718-fold) gene markers. Furthermore, the physicochemical characteristics of the nanofiber mixture significantly influenced the proliferation and differentiation of human adipose mesenchymal stem cells. The results of the tests showed that silk fibroin administration into a nanofiber mixture has improved chondrogenesis and showed great potential as a cartilage tissue scaffold.
Association between BMI, Immunocompromised Status, and Pulmonary TB History with Severity of TB Spondylitis Mulia, Maulidia; Supartono, Basuki; Yulianti, Retno; Amalia, Muttia
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol. 14 No. 2 (2025): SEPTEMBER 2025
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v14i2.4725

Abstract

Abstract Background: Tuberculous spondylitis is the most common form of skeletal TB that can cause joint damage and disability if left untreated. Several studies have discussed risk factors associated with the severity of TB spondylitis. However, there are differences in findings among these studies, especially regarding age, sex, body mass index, immunocompromised conditions, and pulmonary TB history. Early detection through risk factor screening and adequate treatment can be useful to prevent disease severity. Objective: This research aims to find out the association between risk factors and the severity of TB spondylitis using GATA classification. Methods: Observational analytical methods with a retrospective hospital-based cross-sectional study design were used. Using consecutive sampling technique. The total research sample was 50 patients diagnosed with TB spondylitis between January 1, 2022-December 31, 2024 at Gatot Soebroto Army Hospital Jakarta. Result: The characteristics of TB spondylitis patients were mostly adults (68%), male (54%), had normal BMI (42%), had immunocompromised conditions (52%), and had a history of pulmonary TB (58%), with severe TB spondylitis (42%). Bivariate analysis showed a significant association between BMI (p=0.033) and immunocompromised conditions (p=0.047) and no significant association between age (p=0.482), sex (p=0.356), and history of pulmonary TB (p=0.469) with the severity of TB spondylitis. Conclusion: A significant association was found between BMI and immunocompromised conditions with the severity of TB spondylitis. However, there is no significant association between pulmonary TB history with the severity of TB spondylitis.Keywords: risk factors, tuberculous spondylitis, severity
Pemberdayaan Kader Melalui Hidroponik pada Lahan Sempit sebagai Upaya Preventif Diabetes Melitus Retno Yulianti; Andri Pramesyanti Pramono; Boenga Nurcita
Jurnal Abdimas Mahakam Vol. 4 No. 1 (2020): Januari
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/jam.v4i1.805

Abstract

Permasalahan yang terjadi sebanyak 15 persen penduduk Depok menyandang penyakit diabetes melitus serta penyebab kematian sekitar 6.84%. Kurangnya perhatian penyandang diabetes terhadap upaya preventif menanggulangi komplikasi diabetes, maka upaya yang dapat dilakukan melalui bercocok tanam dengan hidroponik meskipun memiliki pekarangan yang sempit. Tujuan kegiatan adalah agar kader Posbindu di RW 05 Kelurahan Gandul dapat meningkatkan pengetahuan, sikap dan ketrampilan, meningkatkan kesadaran masyarakat untuk memanfaatkan barang bekas sebagai upaya mengurangi keberadaan sampah plastik  serta memberi pengetahuan peluang wirausaha baru dari hidroponik. Metode kegiatan adalah memberikan penyuluhan kesehatan dan pembekalan hidroponik sistem Wick, diskusi dan tanya jawab serta demonstrasi dan praktek mandiri dengan menggunakan barang bekas. Evaluasi kegiatan dengan melihat kehadiran dan antusiasme kader dalam diskusi dan praktek serta penilaian pretest dan postest. Hasil kegiatan adalah kehadiran peserta kader sebanyak 93,3%, peningkatan pengetahuan sekitar 80% dan peningkatan sikap positif kader menjadi 92,86% dari total peserta terhadap hidroponik, antusiasme kader yang tinggi lewat interaksi pada saat praktek budidaya hidroponik, serta membuat wadah tanaman dari barang bekas. Kesimpulan kegiatan adalah para kader RW 05 telah menerapkan pemanfaatan lahan pekarangan dengan bercocok tanam, sehingga pembekalan hidroponik dapat memberikan peningkatan pengetahuan dan keterampilan budidaya sayuran dalam pot/wadah dari barang bekas dan dapat mendukung ketahanan pangan keluarga.   
Productive Economic Improvement in the time of COVID-19 Pandemic for the People of Kampung KB Gandul with Innovation of "Mi Jaren" (Palm Sugar Ginger Lemongrass Drink) Andri Pramesyanti Pramono; Yudhi Nugraha; Retno Yulianti
Journal of Innovation and Community Engagement Vol. 3 No. 2 (2022)
Publisher : Faculty of Smart Technology and Engineering, Universitas Kristen Maranatha, Bandung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/ice.v3i2.4150

Abstract

Coronavirus disease originating from Wuhan, China, has spread throughout the world, including in Indonesia. Covid-19 patients were first detected in Depok, Cinere, West Java, and increased on June 20, 2020. There have been 45,029 positive cases of Covid-19 on June 2021. Gandul Cinere village is located bordered by South Jakarta. Jakarta has a relatively high number of Covid-19 positive patients. Many people lost their jobs during the pandemic, including in the Jakarta and surrounding areas. Anis Baswedan, the governor, expects the unemployment rate due to the Covid-19 Pandemic in the DKI Jakarta area will reach 10 percent in 2021. This shows that economic problems cannot be ruled out easily. Therefore, efforts are needed to improve the economy of UMKM (Usaha Mikro Kecil dan Menengah) to further strengthen Indonesia's economy, especially in the DKI Jakarta and surrounding areas. Red Ginger (Zingiber officinale var Rubrum) and lemongrass (Cymbopogon citratus) are easy to find in Indonesia. Palm Sugar Ginger Lemongrass (MI JAREN) instant drink is an excellent herbal product to be studied and marketed in the Gandul village community. This instant herbal drink-making training was provided online, along with how to package it. The activity results showed that society in Kampung KB Gandul has good knowledge, only still requires guidance for the marketing, especially online. It is hoped that this community service activity can improve the economy in Kampung KB Gandul while also keeping the people of Kampung KB Gandul to avoid COVID-19 infection.  
Online Education of Clean and Healthy Living Behavior (PHBS) in Overcoming the Spread of SARS COV-2 Virus for Gandul Cinere Village Health Cadre Andri Pramesyanti Pramono; Lisa Safira; Retno Yulianti; Nanang Nasrullah; Novri Rahmadika
Journal of Innovation and Community Engagement Vol. 3 No. 3 (2022)
Publisher : Faculty of Smart Technology and Engineering, Universitas Kristen Maranatha, Bandung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28932/ice.v3i3.4171

Abstract

Gandul Cinere village is located bordered by South Jakarta. Jakarta has a fairly highnumber of SARS-COV 2 positive patients. The Indonesian Government has determined thatIndonesia is entering the New Normal era in June 2020. Many people in the community donot care about health protocols in the New Normal era and consider that the Covid-19pandemic is no longer a threat. Our goals are (1) increasing PHBS knowledge andawareness of health cadres to implement PHBS and to teach the community in everyday lifein the New Normal era, and (2) decreasing incidence of Covid-19 related illness in GandulCinere Village. Therefore, a continuous understanding of health protocols is needed. PHBSis part of the health protocol that must be run in this New Normal era. Continued knowledgeprovision is required in order to prevent the transmission of Covid-19, especially in theGandul Village area, Cinere, which borders the red zone area of Covid-19. Health cadreswho are the vanguard need assistance and guidance in understanding and applying PHBS ineveryday life. The methods used were online counseling, online discussion, online mentoring,and pre-/post-test implementation. The result showed increased knowledge about Clean andHealthy Living Behavior after given counseling and discussion with the respondent.
Efektivitas Ekstrak Daun Sirsak (Annona Muricata) Terhadap Kadar Malondialdehid Hepar Tikus Diabetik Setelah Diinduksi Aloksan Retno` Yulianti; Lina Adilla; Imam Prabowo
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 6 No. 2 (2019)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v6i2.5134

Abstract

Hiperglikemik yang tidak terkontrol memicu pembentukan reactive oxygen species (ROS) yang berlebih di dalam tubuh sehingga menyebabkan peroksidasi lemak pada membran sel. Regulasi jumlah ROS dapat diukur melalui kadar malondealdehid. Tujuan penelitian ini untuk mengetahui efektivitas ekstrak daun sirsak (EDS) terhadap kadar Malondialdehid hepar tikus diabetik. Sebanyak 30 ekor tikus putih jantan galur Wistar dikelompokkan menjadi (K1) pakan standar dan aquades, (K2) pakan tinggi lemak dan vitamin E α-tokoferol 150 IU/kgBB/hari, dan kelompok yang menggunakan pakan tinggi lemak dengan tiga dosis EDS 75 mg/kgBB/hari (K3), 150 mg/kgBB/hari (K4), dan 300 mg/kgBB/hari (K5). Ekstrak daun sirsak diberikan selama 21 hari setelah hari ke-3 induksi aloksan dan pakan tinggi lemak selama 5 minggu. Analisis data menggunakan uji One Way ANOVA dan dilanjutkan dengan uji Post Hoc Least Significant Differences. Hasil penelitian menunjukkan bahwa pada kelompok perlakuan K4 dibandingkan kelompok perlakuan K3, K5 dan kelompok kontrol K2 menunjukkan penurunan kadar gula darah puasa (131,1 mg/dL) dan kadar Malondialdehid (0.35796 nm/mL) yang lebih baik. Kesimpulan penelitian ini bahwa ekstrak daun sirsak efektivitas menurunkan kadar Malondialdehid dengan dosis optimal 150 mg/kgBB/hari.