Article Per Year (5 Year)
p-Index From 2021 - 2026
3.48
P-Index
This Author published in this journals
All Journal Science and Technology Indonesia Journal of Pharmaceutical and Health Research FORTE JOURNAL Mejuajua Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Health Research Journal of Indonesia Journal of Pharmaceutical and Sciences. Journal of Innovative and Creativity Servitia: Journal of Community Service and Engagement
Syarifah Nadia
Department Of Pharmacy, Tjut Nyak Dhien University, Medan, 20123, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Other

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
Formulasi dan Karakterisasi Fisikokimia Gel Ekstrak Etanol Daun Glodokan Tiang (Polyalthia longifolia) sebagai Antibakteri Topikal terhadap Staphylococcus aureus Syarifah Nadia; Siti Muliani Julianty; Dilla Salsabila
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1342

Abstract

Infeksi kulit oleh Staphylococcus aureus memerlukan alternatif bahan antibakteri yang efektif dan dapat diformulasikan untuk penggunaan topikal. Penelitian ini bertujuan memformulasikan ekstrak etanol daun glodokan tiang (Polyalthia longifolia) menjadi gel, mengevaluasi mutu fisiknya, dan menguji aktivitas antibakteri terhadap S. aureus. Serbuk simplisia sebanyak 500 g dimaserasi menggunakan etanol pro analysis dan menghasilkan 35 g ekstrak kental dengan rendemen 7%. Gel dibuat dalam empat formula, yaitu F0 tanpa ekstrak, F1 1%, F2 1,5%, dan F3 2%. Evaluasi meliputi organoleptik, homogenitas, pH, viskositas, daya sebar, daya lekat, stabilitas enam siklus selama 12 hari, iritasi, dan aktivitas antibakteri dengan metode difusi sumur. Hasil skrining fitokimia menunjukkan ekstrak positif mengandung flavonoid. Seluruh formula homogen, mempunyai pH 4,80–6,06, daya sebar 5,5–6,8 cm, daya lekat 11,15–21,72 detik, dan viskositas 19.720–19.980 mPa·s. Tidak ditemukan perubahan organoleptik bermakna setelah cycling test dan tidak tampak iritasi pada 12 sukarelawan. Diameter zona hambat F1, F2, dan F3 berturut-turut sebesar 15,80 ± 0,56; 16,63 ± 0,51; dan 17,83 ± 0,68 mm, sedangkan F0 tidak menghasilkan zona hambat. Formula F3 menunjukkan aktivitas antibakteri terbesar dan memenuhi parameter mutu fisik yang dievaluasi.
Skrining Fitokimia, Analisis GC-MS, dan Aktivitas Antioksidan (Metode DPPH) Ekstrak Etanol Daun Sirih Cina (Peperomia Pellucida (L.) Kunth) Putri Nurjannah; Rahma Yulia; Syarifah Nadia
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1562

Abstract

Introduction: Peperomia pellucida (L.) Kunth, commonly known as Chinese betel leaf, is a medicinal plant widely used in traditional medicine for various ailments. The plant is reported to contain diverse secondary metabolites with potential pharmacological activities, including antioxidant properties. However, comprehensive information on its phytochemical constituents and antioxidant potential remains limited, particularly for extracts of Indonesian origin. Objective: This study aimed to determine the phytochemical profile, chemical constituents, and antioxidant activity of the ethanol extract of P. pellucida leaves. Methods: Dried leaf powder (100 g) was extracted by maceration using 96% ethanol (1:10 w/v) for 3 × 24 hours at room temperature. Phytochemical screening was conducted using standard qualitative tests for alkaloids, flavonoids, glycosides, saponins, steroids/terpenoids, and tannins. Chemical composition was analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). Antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay, with IC₅₀ values determined by linear regression analysis. Vitamin C served as the positive control. Results: The extraction yielded a concentrated ethanol extract of 11.8% (w/w). Phytochemical screening revealed the presence of flavonoids, glycosides, saponins, and terpenoids/steroids, while alkaloids and tannins were not detected. GC-MS analysis identified 14 chromatographic peaks, with major compounds including methyl hexadecanoate (14.12%), methyl 9-octadecenoate (13.61%), and triacontanoic acid. The ethanol extract exhibited very strong antioxidant activity with an IC₅₀ value of 41.47 µg/mL, compared to vitamin C (IC₅₀ = 4.083 µg/mL). The linear regression equation for the extract was y = 0.4291x + 32.2016 (R² = 0.9985). Conclusion: The ethanol extract of P. pellucida leaves contains various secondary metabolites and demonstrates very strong antioxidant activity. Although GC-MS analysis was predominantly characterized by fatty acid esters, the observed bioactivity likely results from synergistic contributions of multiple bioactive constituents. Further studies employing LC-MS/MS are recommended to identify specific compounds responsible for the antioxidant activity and to quantitatively determine total phenolic and flavonoid contents to establish their correlation with the observed bioactivity.
Penguatan Pembelajaran Kimia Industri Melalui Dukungan Modul Ajar Berbasis Kebutuhan Industri di SMK Negeri 1 Air Putih Pravil Mistryanto Tambunan; Aldella Makhfiza; Masdi Masdi; Rara Pramudhita; Yessi Febriani; Desi Natalia Siahaan; Syarifah Nadia
Journal of Community Service and Engagement Vol 2 No 1 (2026): August: Servitia: Journal of Community Service and Engagement
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/r57g3c39

Abstract

The misalignment between vocational education curricula and dynamic industrial requirements contributes significantly to graduate unemployment in the chemical manufacturing sector. This study evaluates a community engagement program designed to strengthen industrial chemistry instruction through the collaborative development and handover of industry integrated teaching modules at SMK Negeri 1 Air Putih in partnership with PT Bakrie Renewable Chemicals. Utilizing a non-empirical, participatory implementation framework, the intervention focused on upstream instructional enhancement without experimental sampling. The program generated a standardized annual teaching module encompassing effective lesson planning, industrial case studies, and safety protocols, thereby shifting instructional approaches toward case based and project based learning. Strategic institutional synergy established clear roles, placing pedagogical design under teacher ownership while the corporate partner provided technical context and document production support. A sustainable roadmap incorporating expert validation, periodic content updates, and digital media integration was established to maintain curriculum relevance. The findings demonstrate that upstream instructional support effectively bridges the school to work transition and reinforces vocational learning quality.  
Co-Authors Aldella Makhfiza Anna Juniar Ariyanti Kesuma Wardani Azkia Putri Ramud Beby Noplya Wulandari Bunga Rimta Barus Dea Anggraini Dea Anggreini Dea Anggreini Desi Natalia Siahaan Dessy Natalia Siahaan Dilla Salsabila Dwinda Dwinda Ernawati Ginting Ernawaty Ernawaty Ernawaty Ginting Eva Sartika Dasopang Fatia Zahra Fatia Zahra Fatimah Az Zahra Siregar Ika Julianti Tambunan Imanuel Damanik Irene Maria Clarita Zebua Jhonyman So’arota Zebua Julva Maulida Kanne Dachi Karina Mia Berutu Kharina Tambunan Linda Margata Maharani Zahra Marcella Maran Gabean Masdi Masdi Melibeni Pakpahan Mera Riska Muflihah Fujiko Muflihah Fujiko Muharni Saputri Nahda Maulida Ulfa Nerdy Nerdy Nerdy, Nerdy Nilsya Febrika Zebua Nilsya Febrika Zebua Nilsya Febrika Zebua, Nilsya Febrika Nor Hafiza Nurmala Sari Nurmala Sari Nurul Karimah Nur’azmi Fadhillah Br Siagian Ovalina Sylvia Br. Ginting Pravil Mistryanto Tambunan Pravil Mistryanto Tambunan Pravil Mistryanto Tambunan Putri Nurjannah Putri Rahmadani Rahma Yulia Rara Pramudhita Salman Salman Saputri, Muharni Siti Muliani Julianty Siti Muliani Julianty siti muliani julianty Siti Rahmi Ningrum Siti Rahmi Ningrum Siti Rahmi Ningrum Sudewi Sudewi Sudewi Supran Hidayat Supran Hidayat Sihotang Supran Hidayat Sihotang Tandra Alexandro Tedy Kurniawan Bakri Tedy Kurniawan Bakri Virda Widya Pratiwi Wanda Octavianti Ahdiansyah Yessi Febriani Yessi Febriani Yohana Catarina Purba Zulmai Rani