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All Journal HAYATI Journal of Biosciences Jurnal Dedikasi Farmasains : Jurnal Farmasi dan Ilmu Kesehatan EKSAKTA: Journal of Sciences and Data Analysis El-Hayah : Jurnal Biologi Pharmaciana: Jurnal Kefarmasian Journal of Biomedicine and Translational Research Jurnal Kesehatan Masyarakat (JKM) CENDEKIA UTAMA Jurnal Ilmiah Biosaintropis (Bioscience-Tropic) Journal of Islamic Pharmacy Jurnal Farmasi Sains dan Komunitas AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Jurnal Biologi Tropis Majalah Farmaseutik SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Eksakta : Berkala Ilmiah Bidang MIPA Medical Technology and Public Health Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Penelitian Farmasi dan Herbal Jurnal Kesehatan Tambusai Nusantara Hasana Journal Jurnal EduHealth AJAD : Jurnal Pengabdian kepada Masyarakat Borneo Journal of Pharmacy
Ahmad Shobrun Jamil
Universitas Muhammadiyah Malang
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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DARI MASJID KE MEDIA: STRATEGI DAKWAH DIGITAL BERBASIS DATA DAN KONTEN KREATIF PEMUDA MUHAMMADIYAH JAWA TIMUR Ahmad Shobrun Jamil; Khasna Shafwatul Jihan; Nabilatul Auliyana; Sumadi, Firasti Agung Nugrahening
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1612

Abstract

Digital transformation in Islamic preaching (dakwah) has become an urgent necessity in the information disruption era. Pemuda Muhammadiyah of East Java, as an active religious youth organization, has strategic potential in utilizing information technology to expand its dakwah outreach. This community service program aimed to strengthen digital dakwah capacity through the development of an information system and training in digital content creation. The method used was a participatory qualitative approach involving the service team, PMM students, and Pemuda Muhammadiyah cadres. Activities included mosque data collection, data input into the pwpmjatim.org website, and the creation of video tutorials on data input and content editing using the Canva application. The results indicate that the program successfully increased cadre involvement in managing mosque information and producing digital dakwah content. Moreover, the mosque database system serves as a synergistic platform for data-driven dakwah. The program concludes that integrating information technology into community-based dakwah movements is essential, alongside expanding the coverage and ensuring program sustainability. Strengthening digital literacy among youth cadres is a crucial foundation for building an adaptive and competitive Muhammadiyah dakwah ecosystem.
POTENSI KAWISTA (LIMONIA ACIDISSIMA) DALAM PENGELOLAAN HIPERTENSI : ANALISIS JEJARING FARMAKOLOGI Pertiwi, Cinta Junaidi Putri; Muchlisin, M. Artabah; Jamil, Ahmad Shobrun; Astuti, Engrid Juni; Rafikayanti, Agustin
Jurnal Kesehatan Tambusai Vol. 5 No. 2 (2024): JUNI 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i2.28226

Abstract

Hipertensi adalah kondisi kronis yang dapat menyebabkan komplikasi kardiovaskular serius, dan kawista (L. acidissima) telah digunakan dalam pengobatan tradisional untuk berbagai penyakit, termasuk hipertensi. Namun mekanisme molekuler L. acidissima dalam mengatur tekanan darah belum sepenuhnya dipahami. Penelitian ini bertujuan untuk menyelidiki potensi kawista L. acidissima dalam pengelolaan hipertensi melalui pendekatan jejaring farmakologi. Senyawa metabolit sekunder L. acidissima diambil dari literatur, protein yang dapat berinteraksi dengan metabolit sekunder diprediksi dengan menggunakan SwissTargetPrediction, protein yang berhubungan dengan hipertensi diperoleh dari GeneCards. Hasil irisan protein dari SwissTargetPrediction dan GeneCards dianalisis lebih lanjut menggunakan STRING dengan metode GO (Gene Ontology) dan KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment. Protein yang paling memiliki peranan dalam hipertensi dianalisis dengan menggunakan algoritma MCC (Maximal Clique Centralit) dari CytoHubba. Analisis GO enrichment menunjukkan keterlibatan protein-protein dalam regulasi tekanan darah sistemik dan respons biologis lainnya yang relevan dengan hipertensi. Analisis KEGG enrichment mengungkap keterlibatan jalur-jalur sinyal utama seperti cGMP-PKG dan HIF-1, serta jalur regulasi hormonal penting dalam regulasi tekanan darah. Analisis MCC top 10 dari CytoHubba menyoroti peran sentral gen-gen seperti ACE, NOS3, dan EDNRA dalam jaringan biologis, menunjukkan potensi mereka sebagai target terapeutik dalam pengelolaan hipertensi. Senyawa metabolit sekunder L. acidissima memiliki potensi digunakan sebagai terapi untuk hipertensi.
Integrative Network Pharmacology Unveils Limonia acidissima as a Potential Natural Product for Targeting Cancer Wahyuni, Reni Sri; Muchlisin, M. Artabah; Jamil, Ahmad Shobrun; Astuti, Engrid Juni; Rafikayanti, Agustin
Borneo Journal of Pharmacy Vol. 7 No. 3 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i3.6988

Abstract

Cancer remains a formidable health challenge worldwide, with complex molecular mechanisms driving its initiation, progression, and therapeutic resistance. In this study, we employed bioinformatics analyses to elucidate the molecular underpinnings of cancer biology, focusing on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. Our GO analysis revealed the enrichment of key biological processes such as protein phosphorylation, regulation of programmed cell death, and transmembrane receptor signaling pathways, underscoring the critical roles of signaling cascades and regulatory mechanisms in tumorigenesis. Similarly, molecular functions such as protein kinase activity and ATP binding were identified as significantly enriched, highlighting the importance of protein kinases and molecular interactions in cancer development and progression. The KEGG pathway analysis further delineated dysregulated signaling pathways associated with cancer, including the MAPK and PI3K-Akt signaling pathways, implicating these pathways as central regulators of cancer progression. These findings deepen our understanding of cancer biology and offer potential targets for therapeutic intervention. Integrating multi-omics data and systems biology approaches may provide deeper insights into the intricate networks underlying cancer pathogenesis, paving the way for developing more effective treatments for cancer patients.
Penyuluhan Penggunaan Obat yang Benar (Dagusibu) dan Pengelolaan Obat di Rumah Tangga Masyarakat Bumi Mondoroko Raya Malang Syifa', Nailis; Puspitasari, Alvina Arum; Jamil, Ahmad Shobrun
AJAD : Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 3 (2025): DECEMBER 2025
Publisher : Divisi Riset, Lembaga Mitra Solusi Teknologi Informasi (L-MSTI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59431/ajad.v5i3.607

Abstract

Insufficient public knowledge about appropriate medication use, storage, and disposal practices poses significant health risks and environmental hazards. This community service program sought to enhance understanding of the Dagusibu concept (obtain, use, store, dispose) among PKK mothers in Bumi Mondoroko Raya, Singosari, Malang. The intervention employed pre-test questionnaires, interactive presentations, and question-and-answer sessions involving 13 participants. Pre-test findings revealed substantial misconceptions: eight participants (62%) perceived paracetamol solely as an antipyretic, four participants (31%) deemed household waste disposal acceptable for all expired medications, and three participants (23%) believed antibiotics were available for purchase at local stalls. Following the educational intervention and discussion sessions, participants demonstrated accurate identification of paracetamol's multiple therapeutic indications, appropriate disposal protocols for expired medications, and prescription requirements for antibiotic acquisition. The program successfully enhanced community knowledge regarding rational medication use and household pharmaceutical management. Educational leaflets were disseminated as follow-up materials, with plans established for ongoing monitoring of household medication storage practices.
Co-Authors Ahyana Fitrian, S.Farm. Apt Ahyana Fitrian, S.Farm. Apt, Ahyana Fitrian, Alamsyah, Fakhruddin Almutahrihan, Irsan Fahmi Amaliyah Dina Anggraeni Andika Aliviameita Aris Soewondo Astri Ariani Astri Ariani, Astri Asyhari, Firda Nuri Azka Khoirunnisa Bayu Prasaja Bayu Prasaja, Bayu Buhari Adi, Buhari Buhari Buhari Burhanuddin Burhanuddin Burhanuddin Burhanuddin Dikky Syadqamullah Dina Siti Rahma M. Hentu Dinda Farida Dliyauddin, Moh Dra. Uswatun Chasanah, Apt. Dra. Uswatun Chasanah, Apt., Dra. Uswatun Drs. Ahmad Inoni, Apt Drs. Ahmad Inoni, Apt, Drs. Ahmad Dwi Retno Nur Syahida Eko Budi Cahyono Engrid Juni Astuti Faiznanda Awwaluddin Fakhruddin Alamsyah Fath, Dwi Hanif Muluqul Fitria Dwi Damayanti Hentu, Dina Siti Rahma M. Hidayaturrahman Hidayaturrahman Hidayaturrahman, Hidayaturrahman Hilmy, Fauzan Irsan Fahmi Almuhtarihan Irsan Fahmi Almutahrihan Izuddin Karim Karim, Izuddin Khasna Shafwatul Jihan Lely Mauliana Lena, Nour Lilik Yusetyani Luqman Hakim Luqman Hakim M Artabah Muchlisin M. Artabah Muchlisin M. Artabah Muchlisin M. Helmi Mansur Ibrahim Miftahul Mushlih Moch Sasmito Djati Muchlisin, M. Artabah Muhammad Halim Natsir Mujahidin Ahmad Nabilatul Auliyana Nour Lena Nurul Amalia Azhari Nuryasin, Ilyas Pertiwi, Cinta Junaidi Putri Puspitasari Puspitasari Puspitasari, Alvina Arum Putri, Nenis Try Melani Rafikayanti, Agustin Resi Puguh Prihantono Rifa’i, Muhaimin Risma Ayu Setiawan Satriawan, Herland Siti Rofida Solly Aryza SRI RAHAYU Sumadi, Firasti Agung Nugrahening Syabana, Nada Laela Syadqamullah, Dikky Syifa', Nailis Thoat Stiawan Tri Luthfiana Maretha Trikxy Viori Andhani Trimianti Hidahyatun Nazah Veda, Adella Infia Helga wahyuni, reni sri Zulfatim, Heni Sukma Zulkipli Hardi Zulkipli Hardi, Zulkipli