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PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF SOFT CORAL Nephthea sp. EXTRACT ISOLATED AGAINST Escherichia coli Setyaningrum, Tri Wahyu; Nurulfadilah; Candri, Dining Aidil; Dharmayani, Ni Komang Tri; Ghazali, Mursal; Faturrahman
BIOMA : Jurnal Ilmiah Biologi Vol. 15 No. 1 (2026): April 2026
Publisher : Prodi Pendidikan Biologi, FPMIPATI, Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/bioma.v15i1.3070

Abstract

This study aimed to evaluate the antibacterial potential of Nephthea sp. extract against Escherichia coli and to analyze the phytochemical constituents present in Nephthea sp. using various solvents. The extraction process was carried out using the maceration method with three different solvents: n-hexane, ethyl acetate, and methanol. The resulting extracts were analyzed through phytochemical screening and antibacterial activity assays. The results showed that Nephthea sp. extract contained several classes of bioactive metabolites, including alkaloids, flavonoids, triterpenoids, steroids, tannins, and saponins. Antibacterial testing demonstrated that the ethyl acetate extract produced the largest inhibition zone, measuring 3.16 mm. Based on the ANOVA test results, the 25% concentration showed a significant effect on the inhibition zone. Based on phytochemical analysis, the ethyl acetate extract contained triterpenoid compounds, whereas the other solvents did not
Concentrations of Heavy Metals Pb and Cd in Porites lutea Coral in Mandalika Coastal Waters Zahara, Asha Aulia; Candri, Dining Aidil; Ahyadi, Hilman; Rahayu, Rachmawati Noviana; Suana, I Wayan
JURNAL BIOS LOGOS Vol. 15 No. 2 (2025): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v15i2.60222

Abstract

The Mandalika Coastal Area, located in Central Lombok Regency, is a row of beaches and bays that have a large coral reef ecosystem and intertidal zone area. The increasing growth of activities on the Mandalika coast will affect the life of the coral reef ecosystem, one of which is the concentration of heavy metals that exceeds the quality standard limits which will be very dangerous for coral reefs. This study aims to determine the concentration of the heavy metals lead and cadmium in Porites lutea coral reefs in Kuta, Tanjung Aan and Gerupuk beaches. Research data collection (field and laboratory) was carried out in May 2023. Coral reef preparation was carried out at the Advanced and Analytical Biology Laboratory, FMIPA, University of Mataram and measurements of heavy metal content were carried out at the Environmental Laboratory, the West Nusa Tenggara Province Environment and Forestry Service. Measurement and calculation of heavy metal content using Atomic Absorption Spectrophotometry (AAS). The results showed that the concentrations of the heavy metals lead and cadmium in Porites lutea coral reefs are < 0.0005 mg/L and < 0.0001 mg/L, which are still below the quality standards (PPRI No.22 of 2021 concerning Sea water Wuality Standards on Marine Biota). The Bioaccumulation Factors (BAF) value in all samples of P. lutea coral in Mandalika coastal waters is 0.00 mg/L, this shows that there is no accumulation of heavy metals in P. lutea coral.
KANDUNGAN EKSTRAK DAUN BANTEN (Lannea coromandelica (Houtt.) Merr.) OBAT TRADISIONAL LOMBOK SEBAGAI ANTIPIRETIK PADA MENCIT (Mus musculus) Wanda Qoriasmadillah; Nirwana Haqiqi; Zuhratul Iman; Tri Wahyu Setyaningrum; Dining Aidil Candri; Andri Frediansyah; Eka Sunarwidhi Prasedya
Jurnal Penelitian Pendidikan IPA Vol 10 No 4 (2024): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i4.6756

Abstract

The Sasak tribe, who are the indigenous inhabitants of Lombok Island, use banten (Lannea coromandelica (Houtt.) Merr.) leaves as a medicinal plant to reduce fever. Fever is a physiological response to infection, characterized by a body temperature above the normal range of approximately ± 37 ℃. If left untreated, fever can cause dehydration, lack of oxygen, nerve damage, dizziness, decreased appetite, weakness, and muscle pain. To minimize these effects, antipyretics such as paracetamol can be used. However, prolonged or excessive use of paracetamol can cause hepatotoxicity, hepatic necrosis, renal tubular necrosis, and hypoglycemic coma.  Therefore, it is necessary to develop alternative herbal medicines to treat fever. The aim of this study is to determine the content and antipyretic effect of banten leaf extract, which was obtained through ethanol extraction. The antipyretic ability test utilized five groups: the negative control group, positive control group, and test groups receiving doses of 1 mg/25gBB, 3 mg/25gBB, and 10 mg/25gBB of ethanol extract of banten leaves. Fever induction was induced using the DPT-HB vaccine. The study found that the ethanol extract of banten leaves contained flavonoids (572.38 mg QE/gram extract), phenols (200.82 mg GAE/gram extract), and antioxidants (2.5063 mg GAE/gram extract with DPPH). The percentage of antioxidant inhibition in banten leaves between 9.68-47.16 %. Additionally, all test groups of the ethanol extract of banten leaves exhibited antipyretic activity. The antipyretic effect of the 3 mg/25gBB dose was equivalent to that of paracetamol. Similarly, the antipyretic effect of the 10 mg/25gBB dose was almost identical to that of paracetamol at 5 hours after treatment.
Sebaran jenis Fitoplankton pada Ekosistem Mangrove, Lamun dan Terumbu Karang di Perairan Sekotong Barat, Lombok Barat Aina Ul Mardiati; Dining Aidil Candri; Sri Puji Astuti; Hilman Ahyadi; Sukiman
Jurnal Penelitian Pendidikan IPA Vol 11 No 1 (2025): January
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i1.8164

Abstract

The West Sekotong coastal area, which includes mangrove, seagrass, and coral reef ecosystems, is rich in marine biota, particularly phytoplankton communities. These ecosystems have been designated as conservation areas; however, increasing exploitation and disturbances in the region have impacted the presence and distribution of phytoplankton. This study aimed to assess the distribution, abundance, and species diversity of phytoplankton across these three ecosystems. Using purposive sampling, phytoplankton communities were identified microscopically, revealing a total of 742 phytoplankton cells, with 264 cells in the mangrove, 258 cells in seagrass, and 220 cells in the coral reef ecosystems. The class Bacillariophyceae dominated across all ecosystems. Specific species dominance varied, with Skeletonema costatum prevailing in mangroves, Nitzschia sigmoidhea in seagrass, and Coscinodiscus radiatus in coral reefs. The highest similarity index (35.89%) was observed between mangrove and seagrass ecosystems, while the lowest (30.87%) occurred between mangrove and coral reefs. The species richness index (R) was high in all ecosystems, ranging from 6.45 to 10.26, and dominance indices were low, indicating a balanced community structure. Environmental parameters measured across the ecosystems showed no significant differences and met the quality standards for marine biota as per KEPMENLH No 51 2004.
Co-Authors AA Ngurah Nara Kusuma Abdus Sabil, Abdus Adhawati, Laela Ahmad Jupri Ahmad Jupri Ahyadi, Himan AIDA MUSPIAH Aina Ul Mardiati Aina Ul Mardiati Amalia, Yunda Fitri Rizky Andri Frediansyah Anisa Nurfitriani Arben Virgota Arben Virgota Arianti, Alya Artiningrum, Novitaa Tri Aulia Zahara, Asha Aulia, Nurul Waroatul Bagus Hakimi Baiq Farista Baiq Farista Baiq Farista Berliana, Cok Gea Derksen, Engelina Noer Soraya Destiana, Elvina Dewi, Saskia Septina Eka Prasedya Sunarwidhi Eka Sunarwidhi Prasedya Engelina Noer Soraya Evy Aryanti Farista, Baiq Faturrahman Fidyantini, Findi Galuh Tresnani Gusti Ngurah Eka Putra Hasanto, Rizki Primaditya Hidayat, Ismadi Dwi Saputra Hilman Ahayadi Hilman Ahyadi Hilman Ahyadi Hilman Ahyadi I Putu Bayu Putra Kastawan I Wayan Suana I WAYAN SUANA Ida Wayan Brahmanda Menu Wedham Immy Suci Rohyani Intan Pandini Irawan, Muhammad Rizki Putra Isnaini Marliana Kartini Ambarwati Kholidah, Baiq Maylina Kurniawan, Ali Laela Junnita Hidayati Laily Hunawatun Sani Lalu Japa, Lalu Lestari, Dinda Propita Lestari, Novidya Aulia Lia Mar’atus Sholeha Luh Putu Ayu Damayanti, Luh Putu Ayu M. Subandi Rahmani Mardiati, Aina Ul Martha, Eriko Thopan Muhammad Syach Maulad Ichfa Muhammad Syach Nuzul Firdauzy Munawaroh, Anggi Nurhardiyanti Murdani, Muhammad Taufiq Zulfikri Muspi’ah, Aida Ningrum, Audya Septria Nirwana Haqiqi Novida Sari Novita Tri Artiningrum NOVITA TRI ARTININGRUM Nur Indah Julisaniah Nurhairani Nurhairani, Nurhairani Nurhayati, Nurhayati nurrijawati Nurrijawati, Nurrijawati nurulfadilah Pardede Shinta Trilestari Pazila, Baiq Dinda Aluh Putri Permatasari, Baiq Dewi Prasedya, Eka Sunarwidhi Pratiwi, Baiq Dwi Sekarjati Rabiatul Adawiyah Rahayu, Rachmawati Noviana Ramdhiani, Arsyka riandinata, selamet kurniawan Rindahmawati, Rika Rizki, Anis Syakiratur Rizkia Apriani Rosiyani, Amita Dwi Royani, Baiq Nurlatifa Saputri, Ferza Ayu Sasmitha, Yuan Sebastian Aviandhika Shofiana, Dwi Auliya Slamet Kurniawan Riandinata Sri Puji Astuti Sukiman . Sukiman Sukiman Sukmaraharja Aulia Rachman Tarigan Suripto Suripto Suripto Suryadi, Bambang Fajar Syahadatina, Rifqah Hashifah Syakiratur Rizki, Anis Thabrani, Rijal Tri Dharmayani, Ni Komang Tri Mulyaningsih Tri Wahyu Setyaningrum Tri wahyu Setyaningrum Tri Wahyu Setyaningrum, Tri Wahyu Ulfaturrahmi, Martina Ulya Nisa Afifa Virgota, Arben Wanda Qoriasmadillah Yuliadi Zamroni Yuliadi Zamroni Yuliadi Zamroni Zahara, Asha Aulia Zain, Baiq Kharisma Afrilia Putri Zuhraini Zuhratul Iman