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Profile of Flexible Fiberoptic Laryngoscopy Examination Before and During the COVID-19 Pandemic in the ORL-HNS Outpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2018–2021 Salsabila, Aisyah Nur; Perdana, Rizka Fathoni; Awalia, Awalia; Purnami, Nyilo
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.155-161

Abstract

Highlights: No differences were observed in any of the variables before and during the COVID-19 pandemic. Only diagnosis variables differed between before and during the COVID-19 pandemic.   Abstract Introduction: Flexible fiberoptic laryngoscopy (FOL) is indicated for various conditions in patients with abnormal upper airway anatomy. This study aimed to determine the profile of flexible FOL examinations at the Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) outpatient unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from 2018 to 2021. Methods: This retrospective study used secondary data from medical records of patients who underwent flexible FOL examinations at the ORL-HNS outpatient unit from 2018 to 2021. The inclusion criteria consisted of patients’ medical records who had complete profiles, successful laryngoscopy, and diagnoses that met the specified variable criteria. Results: A total of 723 patients underwent flexible FOL at the ORL-HNS outpatient clinic during the study period. Before and during the coronavirus disease (COVID-19) pandemic, most of these patients were males, between 20 and 59 years old, unemployed, and lived out of town. The most common procedure before and during the COVID-19 pandemic was FOL. Laryngomalacia was the common diagnosis before the COVID-19 pandemic. Malignancy in the larynx was the common diagnosis during the COVID-19 pandemic. Conclusion: The variables age, sex, place of residence, occupation, and type of action remained consistent before and during the COVID-19 pandemic. However, the diagnosis variable had different results.
Distilasi Uap untuk Meningkatkan Kualitas Minyak Kelapa Sawit (CPO) sebagai Upaya Menghasilkan Pembawa Sediaan Farmasi Angelina Margaretha Ardiani; Isadiartuti, Dewi; Nuzul Wahyuning Diyah; Purnami, Nyilo
Berkala Ilmiah Kimia Farmasi Vol. 12 No. 2 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v12i2.80965

Abstract

Indonesia is the world's largest palm oil producer. In the pharmaceutical sector, palm oil has the potential to be used as an excipient in pharmaceutical dosage forms. Indonesian palm oil, which accounts for 58% of world production, has potential as a pharmaceutical excipient due to its fatty acid content and vitamin E, which have antibacterial and antioxidant activities. However, before being used as a carrier for pharmaceutical preparations, palm oil needs to meet SNI standards (specific gravity, water content, free fatty acids) and the Indonesian Pharmacopoeia (peroxide value, iodine value, refractive index). This study aims to purify CPO through two cycles of steam distillation and test the physicochemical parameters before and after the distillation process with One-Way ANOVA analysis at α = 0.05. Palm oil (CPO) was distilled at a temperature of 95 ± 0.5 °C for 4.5 hours. The palm oil that had been distilled twice was evaluated for oil quality. Research data shows that two-cycle distillation significantly reduces specific gravity, water content, free fatty acids, peroxide value, and iodine value. However, the resulting palm oil does not yet meet the requirements for pharmaceutical excipients. Steam distillation has been shown to improve CPO quality, but further processing, combined with other physical methods, is required to produce oil that meets pharmaceutical carrier standards.   Keywords: Pharmaceutical Excipient, Palm Oil, Distillation, Crude Palm Oil (CPO), Free Fatty Acid
Co-Authors A Ratna Kartika M, A Ratna Ahmad Suryawan Ahyandi, Syarif Syamsi Airina, Andi Alda, Rieza Rizqy Aldri Frinaldi Alfarika Rosmalia Alfian nurfaizi Alfian Nurfaizi Alfian Nurfaizi Aminuyati Angelina Margaretha Ardiani Anggina Diksita Anita Nuraini Aristya, Meutia Putri artono artono Artono Artono, Artono Asmaradianti, Aryunidya Aulia Sakinah Awalia, Awalia Ayuning Tetirah Ramadhani Baiq Dwi Hadiatul Azni Belanny Dwi Desihartati Berliana Nur Azizah Bintang Napitupulu Brahmono, Aditya Budi Utomo Budi Utomo Cahyani, Makhmudyah Indri Chriscelia Valery So Chriscelia Valery So Cintya Dipta Crysciando Jefryco Putra Dewi Isadiartuti Dewo Aksoro Eddy Bagus Wasito Edith Frederika, Edith Eka Savitri Eka Savitri Falerina, Rosa Fauzi Helmi Fikri Mirza Putranto Firdha, Azizah Amimathul Fis Citra Ariyanto Galih, Antonius Ghaus, Akbar Hamam, Kusumagani Haryuna, Tengku Siti Hajar Hendra Kurnia Rakhma Hendra Kurnia Rakhma I'tishom, Reny Ika Dewi Mayangsari Ilmi, Avida Marisa Inayasari, Syahwina Indira Syahraya Indra Zachreini Indra Zachreini Izzattisselim, Sabrina Jenny Bashiruddin Jenny Bashiruddin Juliandi Harahap Juliandi Harahap Kote Noordhianta Lelyana Sih Afgriyuspita Mahesya, Alvian Wahyu Mahrus A Rahman, Mahrus A Makhmudyah Indri Cahyani Makhmudyah Indri Cahyani Martono Martono Mayangsari, Ika Dewi Myrna Adianti Narottama, Kadek Rama Natasha Supartono Natasha Supartono Ni Made Adnya Suasti Nico Probosutejo Ninuk Dwi Ariningtyas Nugroho, Puguh Setyo Nuniek Nugraheni Nunuk Mardiana, Nunuk Nuraini, Anita Nuramalia, Lady Sherly Nurdiansyah, Achmad Fajar Putra Nurvita, Rani Nurwasis Nurwasis Nuzul Wahyuning Diyah Paulus Liben, Paulus Perdana, Rizka Fathoni Prabowo, Gwenny Ichsan Pralampito, Fajrinka Priyono, Harim Probosutejo, Nico Pudji Lestari Puspa Wardhani Puspita, Dwi Indah Rahma, Safira Respati Ranakusuma Respati Ranakusuma Retno Handajani Risa Etika, Risa Rizka Fathoni Perdana Rizka Fathoni, Rizka Romdhoni, Achmad Chusnu Rosydiah Rahmawati, Rosydiah S.Pd. M Kes I Ketut Sudiana . Sabrina Izzattisselim Sagung Rai Indrasari Sagung Rai Indrasari Salsabila, Aisyah Nur Saputri, Faradila Budi Selfiyanti Bimantara Septriana, Maya Sholehen, Alif Sofia Tiarini Sri Herawati Sriati Sriati Suhariningsih Sulistiawati Sumarman Sumarman Surarso, Bakti Susyana Tamin Susyana Tamin Tiarini, Sofia Tjandra Manukbua Tjandra Manukbua Ummi Imamatal Muttaqin WINARTO Wungu, Citrawati Dyah Kencono Yoga Rahmadiyanto Yoga Rahmadiyanto Yoga Rahmadiyanto Yussy Afriana Dewi Yussy Afriana Dewi Zamrotu Iva Purwanti Zuhria, Ismi