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Hubungan kadar CA 125 dengan karakteristik klinis Diffuse Large B cell Lymphoma Agung Dinasti Permana; Igor Hutabarat; Thaufiq Boesoirie; Bethy S. Hernowo; Rovina Ruslami
Oto Rhino Laryngologica Indonesiana Vol. 49 No. 1 (2019): Volume 49, No. 1 January-June 2019
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v49i1.287

Abstract

Latar belakang: Kadar serum CA 125 telah diketahui mengalami peningkatan pada kasus limfoma non Hodgkin. Kegunaannya dalam menentukan prognosis, tingkat keparahan penyakit, dan follow up pasca terapi limfoma non Hodgkin telah banyak diteliti dan masih didapatkan hasil yang bervariasi. Saat ini belum diketahui mengenai kadar serum CA 125 pada kasus diffuse large B cell lymphoma (DLBCL) yang bermanifestasi di regio kepala dan leher. Tujuan: Mengetahui hubungan kadar serum CA 125 dengan karakteristik klinis pada kasus DLBCL regio kepala dan leher. Metode: Penelitian ini merupakan penelitian potong lintang yang melibatkan 31 subjek penelitian dengan diagnosis DLBCL regio kepala dan leher. Dilakukan pencatatan karakteristik klinis dan penentuan kadar serum CA 125 dengan pemeriksaan Immunoasai dan kemudian dilakukan analisis statistik untuk menentukan hubungan antar variabel. Hasil: Didapatkan peningkatan kadar serum CA 125 pada stadium lanjut dengan p<0,001. Analisis statistik terhadap kadar serum CA 125 dan Kadar Lactic Dehydrogenase (LDH) menunjukkan hubungan yang signifikan (p=0,018) demikian juga hubungannya dengan skorEastern Cooperative Oncology Group (ECOG) dengan nilai p=0,001. Pada penelitian ini tidak terdapat hubungan yang bermakna antara kadar serum CA 125 dengan skor Prognostic International Index (IPI). Kesimpulan: Kadar serum CA 125 berhubungan bermakna dengan stadium klinis, kadar LDH dan Skor ECOG pada DLBCL yang bermanifestasi di regio kepala dan leher. Dengan demikian CA 125 dapat digunakan sebagai marker untuk memprediksi prognosis dan mendekati stadium lanjut kasus limfoma non Hodgkin. Background: Serum CA 125 level has been known to increase in Non-Hodgkin Lymphoma cases.Many studies had elaborately researched the prognosis, disease severity and the follow up of Non Hodgkin Lymphoma cases using CA 125, yet the results had been varied. Up to now, serum CA 125 levels in cases of diffuse large B cell lymphoma (DLBCL) which manifest in the head and neck region, is still unclear. Purpose: To find out the correlation of serum CA 125 levels with clinical manifestations of DLBCL cases in the head and neck region. Method: A cross-sectional study involving 31 subjects diagnosed with DLBCL in the head and neck region. The clinical manifestations were recorded and serum CA 125 levels were obtained by Immunoassay examination. Statistical analysis was performed to determine the correlation between variables. Results: An increase in serum CA 125 levels at an advanced stage with p <0.001. The statistical result of CA 125 serum levels and LDH levels showed a significant correlation (p=0.018), as well as its significant correlation with the Eastern Cooperative Oncology Group (ECOG) score, with p=0.001. In this study there was no significant correlation between CA 125 serum levels and Prognostic International Index (IPI) scores. Conclusion: Serum CA 125 levels were significantly correlated with clinical stage, LDH level and ECOG score of DLBCL which manifested in the head and neck region. Therefore, CA 125 might be used as a marker to predict prognosis and to detect advanced disease in Non-Hodgkin Lymphoma cases.
Counseling on Vaname Shrimp Cultivation Using the Biofloc Method to Communities in Dowora Village, Tidore Kepulauan City Sardi Titaheluw, Syahnul; Tangke, Umar; Talib, Ahmaad; Laitupa, Ibnu; Bafagih, Aisyah; Andriani, Rovina; Tan, Fathnun; Lating, Ali
Altifani Journal: International Journal of Community Engagement Vol 3, No 1 (2022)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/altifani.v3i1.5342

Abstract

The purpose of carrying out this community service is to provide information and understanding to the community in the Dowora Village, East Tidore District about vannamei shrimp farming using the biofloc method. The community service was carried out in August 2022, at the Office of the Office of Food Security, City of Tidore Islands. The counseling method is carried out in the form of lectures, discussions and questions and answers. Materials from this counseling include management of vannamei shrimp cultivation; feed management; water use and water quality parameters; vannamei shrimp farming with the biofloc system, and introduction to the types of ponds that can be used for vannamei shrimp farming activities with the biofloc system. During the extension activities, the community of prospective vannamei shrimp cultivators was very active in asking questions and discussing the material provided. The conclusion that can be drawn from this PKM activity is that the community is able to understand the material presented about vannamei shrimp farming using the biofloc method, the material presented is acceptable and then pond repairs will be carried out in preparation for cultivation.
Utilizing rGH + Spirulina in Fish Feed to Enhance The Growth and Pigmentation of Betta Fish (Betta, spp.) Abdullah, Nursanti; S Wibowo, Eko; Andriani, Rovina
Journal of Global Sustainable Agriculture Vol 4, No 1 (2023)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/jgsa.v4i1.7340

Abstract

This study aims to evaluate the effect of the addition of growth hormone (rGH) and spirulina flour on the performance of absolute weight growth, survival, feed efficiency, and feed conversion ratio (FCR) of cupang fish (Betta spp.). This study used a completely randomized design (CRD) with four treatments with three replications, i.e., A) Dose of growth hormone 1.5 mg+3 g spirulina flour; B) Dose of growth hormone 2 mg+3g spirulina flour; C) Dose of growth hormone 2.5+3 g spirulina flour; D) Control (no treatment). The results showed that the addition of growth hormone (rGH) and spirulina to commercial feed affected absolute weight growth of 2.27 ± 0.90 g. The survival rate was 75.00±1.11 %, the feed efficiency value was 28.98±1.17 %, and the feed conversion ratio was 1.11±0.022. The highest color intensity was found in treatment C with a score of 6.
Substitution of Artificial Feed With Seaweed Flour (Gracilaria sp.) Against the Growth of Red Tilapia Fish (Oreochromis sp.) Andriani, Rovina; Muhdar, Fatma
Agrikan Jurnal Agribisnis Perikanan Vol. 14 No. 2 (2021): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1483.432 KB) | DOI: 10.52046/agrikan.v14i2.831

Abstract

In fish farming, feed is the highest operational cost, accounting for more than 60% of the total production cost. Therefore, to reduce production costs in aquaculture, fish feed can be made yourself. The purpose of this study was to determine the nutritional content of feed and to determine the effect of artificial feeding with the addition of seaweed flour (Gracilaria sp.) on the growth of Red Tilapia (Oreochromis sp.). This research was conducted in June-September 2021, the research variables consisted of proximate analysis test, specific growth rate (SGR) and absolute growth. Based on the results of the proximate analysis test on feed, it showed that treatment A with the addition of Gracilaria, sp of 10 g gave the best results by looking at the protein content in the feed on average by 60%, while the effect of feeding with the addition of Gracilaria seaweed, sp on the specific growth rate (SGR) is found in treatment C, which is an average of 0.06%, the best absolute growth average is found in treatment C, which is 33.04 gr.
Chemical Characteristics, Sensory Analysis, and Antioxidant Activity Of Artificial Nori Made From Ptilophora pinnatifida With The Addition Of Moringa oleifera Leaves Wulansari, Angela; Dewi, Eka Kusuma; Andriani, Rovina; Rasulu, Hamidin
Agrikan Jurnal Agribisnis Perikanan Vol. 15 No. 1 (2022): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1273.59 KB) | DOI: 10.52046/agrikan.v15i1.1007

Abstract

Ptilophora pinnatifida is a red algae that can be found in wild around Indonesia’s ocean. It is a potential raw material for artificial nori. The addition of Moringa oleifera leaves is needed to give green color similar to commercial nori. The aim of this study was produced artificial nori from Ptilophora pinnatifida and Moringa oleifera. This study was an experimental study with variation of Moringa oleifera concentration as the factor. There was three different concentrations of Moringa oleifera (4%, 6%, 8%). Artificial nori was tested for proximate analysis, antioxidant IC50 activity analysis, and Hedonic rating test. The result showed artificial nori had higher water, ash, carbohidrate, and crude fiber content than commercial nori. The protein and fat content of artificial nori were lower than commercial nori. Hedonic test result showed the color, texture, taste, and smell of artificial nori were slighly liked by the panelists. Artificial nori had low antioxidant activity compare to the standard Vitamin C, but artificial nori with 8% addition of Moringa oleifera had higher antioxidant activity than commercial nori. The best artificial nori which had the closest characteristics with commercial nori was artificial nori made from Ptilophora pinnatifida with 8% addition of Moringa oleifera.
Substitution of Shrimp Head Flour and Maggot Flour (Hermetia illucens) on Digestibility of Giant Shrimp (Macrobrachium rosenbergii) Andriani, Rovina; Juharni, Juharni; Muchdar, Fatma; M Samadan, Gamal
Agrikan Jurnal Agribisnis Perikanan Vol. 15 No. 2 (2022): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/agrikan.v15i2.1264

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The research was carried out from April to December 2022 at the Integrated Laboratory at Khairun University. The research design consisted of 4 treatments that were tried, namely: Treatment A: Prawns were given 25% maggot flour + 25% prawn head flour, Treatment B: Prawns were given 20% maggot flour + 30% prawn head flour, Treatment C: Prawns were given 30% maggot flour + 20% shrimp head meal and Treatment D: Giant prawns were fed commercial feed (control). The research variables consisted of feed proximate test, feces test to determine feed digestibility of giant prawns, specific growth rate (LPS), absolute weight growth and survival rate. Based on the results of the feed proximate test showed that treatment D gave the best results by looking at the average feed protein content of 32.51%, the digestibility value was directly proportional to the feed protein value content in treatment D of 23.06%. The specific growth rate (LPS) during maintenance showed that treatment D gave the best treatment with an average growth yield of 0.684%, the best absolute growth was in treatment D with an average value of 0.120 gr. Based on the results of this study it can be concluded that the results of the proximate test of the feed showed that treatment D gave the best results as seen from the average feed protein content of 32.51%, while the digestibility value was directly proportional to the feed protein content in treatment D with an average of 23, 06%.
Analysis of Coral Fish Community Structure in Maitara Island (Sari Mauli Village and Teluk Ake), Tidore Islands City Titaheluw, Syahnul S.; W. Laitupa, Ibnu; Bafagih, Aisyah; Andriani, Rovina
Agrikan Jurnal Agribisnis Perikanan Vol. 16 No. 2 (2023): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52046/agrikan.v16i2.1802

Abstract

This research aims to see the structure of reef fish community in Maitara Island (Ake Bay and Sari Mauli Village). This research was conducted in August 2023 using Visual Method Census. This study found that the number of fish censused at the research site was 497 fish with 50 species dominated by major fish as many as 32 species, target fish as many as 15 species and indicators as many as 3 species. Fluctuations in abundance, diversity and uniformity indices can be used as indicators of coral reef damage. The abundance of major fish in the study site was 0.58-0.60, diversity ranged from 0.29-0.32 and uniformity of major fish ranged from 0.32-0.43. Indicator group abundance ranged from 0.4-0.7, diversity ranged from 0-0.18 and uniformity ranged from 0-0.18. Indicator fish abundance ranged from 0.31-0.39, target fish diversity was 0.37 and uniformity ranged from 0.36-0.54..
Condition of Coral Fish on Maitara Island Ake Bay Village, Kota Tidore Kepulauan Titaheluw, Syahnul Sardi; Naim, Armain; Bafagih, Aisyah; Andriani, Rovina
Agrikan Jurnal Agribisnis Perikanan Vol. 13 No. 2 (2020): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The study was carried out in June - July 2020. Data collection for reef fish using the Visual Method Census method included three (3) roles of fish, namely the role of major fish, indicators and targets. Data analysis in the form of Abundance, Diversity and Dominance. The results showed that the three roles of fish with a total of 86 species from 9 families. Major fish as many as 51 species consisting of families Pomacentridae (9 species), Caesoinidae (1 species), scaridae (2 species) and Labridae (7 species). The role of indicator fish is 15 species with 1 family (Chaetodontidae), and the role of target fish is 20 species consisting of 4 families (Serranidae, Siganudae, Latjunidae and Acanhuridae). The ecological index (Abundant, Diversity and Dominance) of reef fish at the study site is very low, which indicates high pressure on coral reefs and causes loss of ecological function and resilience. Utilization of coral reefs that do not pay attention to sustainability, such as taking coral reefs, haphazardly anchoring ships and bombing carried out decades ago directly impacted reef fish at the research site, where the abundance of fish at the observation station was at a value of 0.03 ind/ m2 and the diversity index does not exceed 0.5 ind/m2.
Utilization of Different Probiotics on Growth and Survival Rate of Blacktail Zebra fish (Dascyllus melanurus) Muchdar, Fatma; Juharni, Juharni; Andriani, Rovina
Agrikan: Jurnal Agribisnis Perikanan Vol 13, No 2 (2020)
Publisher : Sangia Research Media and Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29239/j.agrikan.13.2.222-231

Abstract

Blacktail Zebra fish (Dascyllus melanurus) is more caught the sea by fishermen. There are several limitations which are lower growth and feet effisincy trought the natural  habitat. Hence, an optimal feed combination is consideret  to be provided during fish rearing to increase their growth.  One of ideas was to use probiotic, which is bacteria that are able to decompose organic materials to change toxic compounds is valauable matter  to the environment. For instance, ammonia and nitrite can be converted into free ammonium. The additional in an artificial feed is exfected to gain aquaculture activities. The study was conducted for 56 days from August to October 2019 in Wetlab Kastela  FPK of Khairun University. Experiment  and four treatments were applied using Filling Randomized Design (RAL). The result shows that different additional probiotic effected the growth and survival rate of Blacktail zebra fish. The highest was found in probio7 15 ml/kg feed,  which gave 0,88g of total growth’; and the lowest was 0,27g which was found in the treatment A ((control)/ Water quality was checked  weekly and in normal condition for the growth of the growth of blacktail zebra fish.
Chemical Characteristics, Sensory Analysis, and Antioxidant Activity Of Artificial Nori Made From Ptilophora pinnatifida With The Addition Of Moringa oleifera Leaves Wulansari, Angela; Dewi, Eka Kusuma; Andriani, Rovina; Rasulu, Hamidin
Agrikan: Jurnal Agribisnis Perikanan Vol 15, No 1 (2022): SI: The Turning Point
Publisher : Sangia Research Media and Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29239/j.agrikan.15.1.76-83

Abstract

Ptilophora pinnatifida is a red algae that can be found in wild around Indonesia’s ocean. It is a potential raw material for artificial nori. The addition of Moringa oleifera leaves is needed to give green color similar to commercial nori. The aim of this study was produced artificial nori from Ptilophora pinnatifida and Moringa oleifera. This study was an experimental study with variation of Moringa oleifera concentration as the factor. There was three different concentrations of Moringa oleifera (4%, 6%, 8%). Artificial nori was tested for proximate analysis, antioxidant IC50 activity analysis, and Hedonic rating test. The result showed artificial nori had higher water, ash, carbohidrate, and crude fiber content than commercial nori. The protein and fat content of artificial nori were lower than commercial nori. Hedonic test result showed the color, texture, taste, and smell of artificial nori were slighly liked by the panelists. Artificial nori had low antioxidant activity compare to the standard Vitamin C, but artificial nori with 8% addition of Moringa oleifera had higher antioxidant activity than commercial nori. The best artificial nori which had the closest characteristics with commercial nori was artificial nori made from Ptilophora pinnatifida with 8% addition of Moringa oleifera.
Co-Authors - Sudigdoadi, - Abdullah, Nursanti Abjan, Kadar Achadiyani Achmad, Muhammad Djanib Adi Imam Cahyadi Agnes Agustin, Agnes Agung Dinasti Permana Ahmad Rizal Ahmad Yamin Ahmad, Khamsiah Ani Melani Maskoen Anita Deborah Anwar Anneke Rosma Aras Syazili Ardini Raksanagara ardini raksanagara, ardini Atmaja, Harold Eka Attamimi, Fathimah Azzahra Atu Purnama Dewi Atu Purnama Dewi Bachti Alisjahbana Bafagih, Aisyah Bethy S. Hernowo Billy Talakua Bony Wiem Lestari Budi Setiabudiawan Chiho Yamazaki Cindy Elfira Boom Cindy Elfira Boom Deni K Sunjaya Deni K. Sunjaya Dewi Herawati Dewi M. Herawati Dewi Puspasari Dewi Puspasari Dewi, Atu Purnama Edhyana Sahiratmadja Edy Soewono Eka Kusuma Dewi, Eka Kusuma Emmy Hermiyanti Pranggono Endang Sutedja Farid Husin Farid Husin Febriani, Ulfah Dwi Findra, Muhammad Nur Hamidin Rasulu Harold Eka Atmaja Harold Eka Atmaja Herawati H Herawati, Dewi M. Hikmat Permana Hiroshi Koyama Igor Hutabarat Ikbal Marus, Ikbal Ishak, Safira Juharni Juharni, Juharni Julaecha Julaecha Juni Wijayanti Puspita Kameo, Satomi Kenanga Marwan Koesoemadinata, Raspati C. Koyama, Hiroshi Laitupa, Ibnu Laitupa, Ibnu W Lastri Winarni Lating, Noval Ali Leha, Alicia W Lika Apriani Luntungan, Gloria Vivian M. Irfan M. Irfan, M. Irfan Malan, Sudirto Margono, M. Tirta Marwan, Kenanga Maya Valentina Putrie Maya Valentina Putrie, Maya Valentina Ma’rus, Ikbal Meirina, Triana Nurul Meita Dhamayanti Muchdar, Fatma Muhammad Irfan Muhdar, Fatma Naim, Armain Najamuddin Najamuddin, Najamuddin Nanan Sekarwarna Nanny Natalia Mulyani Soetedjo Novi Jayanti Nurul Safitri Nury Fitria Dewi Pitra, Faisal Ponpon Idrajinata Raesa Yolanda, Raesa Rahmawati, Rika Nurlaily Ratna Anggraeni Renny Rosalita, Renny Rika Nurlaily Rahmawati Rosma, Anneke Rudi Wisaksana S Wibowo, Eko Samadan, Gamal M Sapto Wahyu Indratno Satomi Kameo See Siew Ju Sinta Sari Ratunanda Sofia Imaculata Sophia Sophia Sumaryati Sudigdoadi Sumaryati Sudigdoadi, Sumaryati Supyan Supyan Suryani Gunadharma Suryani Suryani Susan Margaret McAllister Syahnul Sardi Titaheluw Talib, Ahmaad Tamrin, Muhammad Rafly Zulfikar Tan, Fathnun Tatang Bisri Teti Madiadipoera Thaufiq Boesoirie Thaufiq Boesoirie Tina Judistianti Tita Husnitawati Madjid Titaheluw, Syahnul Titaheluw, Syahnul S. Tri Hanggono Achmad Triana Nurul Meirina Triana Nurul Meirina Ulfah Dwi Febriani Umar Tangke, Umar Vera Renta Siahaan Vycke Yunivita Vycke Yunivita Kusumah Dewi W. Laitupa, Ibnu Wahyu Alfishahrin. T, Wahyu WAODE MUNAENI wulansari, angela Yamazaki, Chiho Yuliana Yuliana Yusuf, Masri