Article Per Year (5 Year)
p-Index From 2021 - 2026
4.669
P-Index
This Author published in this journals
All Journal Pharmacon Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Indonesian Community Journal Abdi Geomedisains Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika Jurnal Farmasi Klinik dan Sains Camellia Usadha Journal of Pharmacy
Setyo Nurwaini
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 43 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Pharmacon

 1 
Uji Aktivitas Antijamur Gel Serbuk Lidah Buaya (Aloe vera L.) Berbasis Carbopol 934 Terhadap Candida albicans dan Trichophyton mentagrophytes Hani Afifah; Setyo Nurwaini
Pharmacon: Jurnal Farmasi Indonesia Vol 15, No 2 (2018)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v15i2.7658

Abstract

Fungal infections that occur in the skin and nails were caused by fungi such as Candida albicans and Trichophyton mentagrophytes. Aloe vera contains saponins and acemannan that were effective as an antifungal. This study aims to determine the effect of carbopol concentration variation on aloe vera gel to antifungal activity of Candida albicans and Trichophyton mentagrophytes.Aloe vera powder was obtained from freeze drying aloe vera juice which had been frozen. Aloe vera powder was formulated in gel form using carbopol base with concentration 0.5; 1.0; 1.5; and 2.0 %w/w. The aloe vera gel was tested for its physical properties and then tested the antifungal activity using the diffusion method of wells.The result of evaluation of physical properties showed the high concentration of carbopol then pH, viscosity, adhesiveness increased, and spreading capacity decreased. The results of antifungal activity test showed that aloe vera powder had activity on Candida albicans and Trichophyton mentagrophytes with inhibition zone of 15 ± 3 mm and 13 ± 0,5 mm. Aloe vera gel test results with variation of carbopol concentration 0.5; 1.0; 1.5; and 2.0 %w/w did not affect the antifungal activity of Candida albicans and Trichophyton mentagrophytes.
Formulation and Characterization of Gels of Telang Flower Extract (Clitoria Ternatea L) with Variations of Carbopol Concentration and Antioxidant Activity Test Using DPPH Methods Nurwaini, Setyo; Fatimah, Mutiara Nurul
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23469

Abstract

Telang flower (Clitoria ternatea L) has antioxidant activity. Formulation in gel form provides convenience in the use of telang flower extract. This study aims to determine the effect of carbopol as a gelling agent on the physical properties of the gel and to determine the antioxidant activity of telang flower extract gel. Telang flower extract was obtained by maceration method. The gel was formulated with 3 variations of carbopol concentration, namely 0.5%, 1% and 2%. Characterization of Clitoria ternatea L. gel includes: organoleptic, homogeneity, pH, viscosity, spreadability and stickiness. Antioxidant activity test of telang flower (Clitoria ternatea L) using DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The gel formulation of telang flower extract (Clitoria ternatea L.) from 3 formulas met the requirements. Gel with 2% carbopol concentration was the gel with the best characteristics: pH 5.82; viscosity 2,666 cP; spreadability 4.33 cm; stickiness 2.2 s. The Antioxidant activity test of telang flower extract gel showed strong category with an IC50 value of 97.72 ppm. Carbopol has an influence on the physical properties of telang flower extract (Clitoria ternatea L) gel and strong antioxidant activity of bay flower extract gel.
Formulation And Evaluation Of Telang Flower (Clitoria Ternatea L.) Extract Gel Preparation With Tragacanth As Gelling Agent And Antioxidant Activity Test Nurwaini, Setyo; Amanda, Alifah Tasya
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23470

Abstract

Telang flower has antioxidant activity as a scavenger of free radicals. Formulation in gel form can facilitate its use as a cosmetic preparation. This study aims to determine the characteristics of telang flower extract gel at different concentrations of tragacanth as a gelling agent and its antioxidant activity.Gel formula of telang flower extract with different concentration levels of tragacanth, namely 3%, 4%, and 5%. Gel evaluation includes organoleptic test, homogeneity, pH, spreadability, stickiness, and viscosity. The best formula will be tested for antioxidant activity.Based on the gel characteristics of telang flower extract, F3 has good physical properties, namely pH value of 7.28 ± 0.06, viscosity of 2133.3 ± 23.09 cP, spreadability of 6.05 ± 0.13 cm, and stickiness of 1.17 ± 0.07 seconds. The telang flower extract exhibited an IC50 value of 71.125 ppm, classifying it as strong antixodant. The IC50 value of telang flower extract gel was 92.867 ppm
Optimization of Ethanol Extract Preparation Gel Formula from the Combination of Lime Peel and Neem Leaves : Optimum Physical Properties and Antibacterial Activity Rahmana, Andrea Yovva; Nurwaini, Setyo
Pharmacon: Jurnal Farmasi Indonesia Vol 21, Special Issue 1, 2024
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i0.23586

Abstract

Lime peel (Citrus aurantifolia) and neem leaf (Azadirachta indica) have antibacterial properties, especially against Staphylococcus aureus. These two ingredients can be used to treat various skin problems caused by Staphylococcus aureus. This study aimed to determine the optimal ratio of 96% ethanol extract of lime peel and neem leaves to produce a gel formula with optimum physical properties and antibacterial activity. Physical properties tested were pH test, adhesion test, spreadability test, and viscosity test. Antibacterial activity was measured by inhibition zone diameter when tested by the well method. There were 8 gel formula with the various ratio of components of lime peel and neem leaves extracts, FI (8:2), FII (6.5:3.5), FIII (5:5), FIV (3.5:6.5), FV (2:8). The optimization method used was Simplex Lattice Design using the Design Expert 11 application (Trial). The optimum formula obtained from the Design Expert was verified and analyzed using the SPSS one-sample t-test with a 95% confidence level. The optimum formula of lime peel and neem leaves obtained were 8.00%:2.00% with a desirability value of 0.471. The one sample t-test showed that the results were not significantly different between the predicted and verified values.
Co-Authors Abdellah, Yousra Nait El Haj Abid, Muhammad Maslakul Adilah Purbowati Alkautsar, Hamimatusalma Almira Permata Amanda Wahyu Kurniawan Amanda, Alifah Tasya Ambar Yunita Ambar Yunita Nugraheni Anggraini, Rahma Prasdinar Anggun Tri Wijayanti Anindya, Talitha Ahnaf Anita Sukmawati Anjati, Yasinta Widia Arifah Sri Wahyuni Asti Arum Sari Audi Tahta Aurellia Aurum, Mursalina Nanda Ayu Intan Savitri Azistyna, Delvi Yulia Azizah, Erfinna Nur Azzahra, Annisa Alya Baiti, Nurul Balqis, Moetia Rahman Brainandiva Ade Fitria Cahya Rahma Utami Cholisoh, Zakky Dedi Hanwar Devi Usdiana Rosyidah Diniawati, Widya Diva Ratna Shabrina Emi Erawati Endang Setyaningsih Erindyah Retno Wikantyasning Eryani, Kurnia Fachriani, Galuh Falakhuddin, Muhammad Farida, Rahayu Fatimah, Mutiara Nurul Firdaus, Farhand Ahmad Hani Afifah Harindasari, Amorita Azzah Heppy Purbasari Hidayah Karuniawati Hidayah, Mentari Serlya Ika Trisharyanti Dian Kusumowati Isnaniyah, Dhevi Zahra Latifatul Khoirunnisa Khoirunnisa Krisna Wisnu Wardhana Kurnia Eryani Kurniawati, Yuwandira Larasati, Arindra Lestari, Nining Luluk Ria Rakhma Maryati Maryati Maulana, Fahmi Alief Mawarni, Virga Mentari Serlya Hidayah Mika Tri Kumala Swandari, Mika Tri Kumala Mubarok, Afrizal Muhammad Da'i Muhammad Falakhuddin Muhammad Ikhsan Al Af Ghani Muhammad Raihan Naufal Nasihah, Rosyidah Hafidzatun Naufal, Muhammad Raihan Niken Dyaharesti Nur Mahmudah Palupi, Devita Niken Permata, Almira Pinasthika, Shinta Purbowati, Adilah Rahma Prasdinar Anggraini Rahmana, Andrea Yovva Rajali, Ahmad Ramadhani, Amalia Ramarohasina, Mika Notahiana Ramdani, Tasya Eka Rasma Panji Setiawan Ratsimandresy, Neciah Fahombiazana Refsya Azanti Putri Rima Munawaroh Rita Wijayanti Rosi Hayyu Anjani Rosyidah Hafidzatun Nasihah Salima, Tansa Sania Nayasari Khoirunnisa Savitri, Ayu Intan Septiani, Adiva Metri Setiawan, Panji Rasma Shabrina, Diva Ratna Sulistyani Sulistyani Tansa Salima Tanti Azizah Sujono Tri Agustina, Tri Triyatno, Sabrina Azizah Wahyu Utami Wardhana, Krisna Wisnu Wibowo, Farrel Maulana Widya Diniawati Wijayanti, Anggun Tri Wikantyasning, Erindyah R. Yuka Aulia Rahma Yuniasti, Lainisah Purna Zahidah, Fairus Zahratunisa, Namira