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Lipinwati ., Lipinwati
FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI
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Journal : Journal of Medical Studies

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Uji Beda Leukosit dan NLR (Neutrophil Lymphocyte-Ratio) terhadap Luaran Pasien Sepsis Rawat ICU (Intensive Care Unit) RSUD Raden Mattaher Jambi 2019 - Oktober 2022 Aidil Rahmat Ilham; Lipinwati, Lipinwati; Ahmad Syauqy; Samsirun Halim; Sotianingsih, Sotianingsih; Ekaputri, Tia Wida
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.31935

Abstract

ABSTRACT Background: Sepsis is a clinical syndrome caused by an overreaction of the body's immune response stimulated by microbes or bacteria inside and outside the body. There is visible organ dysfunction. Of an increase of 2 or more scoresSequential Organ Failure Assessment (SOFA). Early diagnosis and treatment by assessing inflammatory factors such as leukocytes and NLR (Neutrophil-to-lymphocyte ratio). This study aims to determine the difference between leukocyte levels and NLR values based on the outcome of septic patients. Method: This study used an analytic observational cohort method with a retrospective and prospective approach involving 54 research subjects, using consecutive sampling. Sampling was done by calculating leukocyte levels and NLR values at 0, 24, 72, and 144 hours in septic patients. Results: The patients who died for more than 24 hours were 36 patients. The highest average results were measured at 24 hours, with leukocytes 17.48 ± 8.49 and NLR 24.96 ± 22.17. The mean leukocyte and NLR levels were higher in the death group. The analysis found no significant difference between the leukocyte and NLR with the outcomes in septic patients (p >0.05). Conclusion: There was no significant difference between leukocytes and NLR with the outcome of septic patients. Keywords: Biomarkers, Leukocytes, Mortality, NLR, Sepsis   ABSTRAK Latar Belakang: Sepsis adalah suatu sindrom klinik oleh karena reaksi yang berlebihan dari respon imun tubuh yang distimulasi mikroba atau bakteri dari dalam dan luar tubuh. Terdapat disfungsi organ yang terlihat. dari peningkatan 2 atau lebih skor Sequential Organ Failure Assessment (SOFA). Diagnosis dan penanganan lebih awal dengan menilai faktor inflamasi seperti leukosit dan NLR (Neutrophil-to-lymphocyte rasio). Penelitian ini bertujuan untuk mengetahui perbedaan antara kadar leukosit dan nilai NLR berdasarkan luaran pasien sepsis. Metode: Penelitian ini menggunakan metode analitik observasional kohort, dengan pendekatan retrospektif dan prospektif yang melibatkan 54 subjek penelitian, menggunakan teknik consecutive sampling. Pengambilan sampel dilakukan dengan cara menghitung kadar leukosit dan nilai NLR pada jam ke-0, 24, 72, dan 144 pada pasien sepsis. Hasil: Dari 54 sampel, hasil luaran pasien meninggal lebih banyak pada jam 24 sebanyak 36 pasien. Rerata hasil tertinggi pada pada pengukuran jam 24 dengan Leukosit 17,48±8,49 dan NLR 24,96±22,17. Rerata kadar leukosit dan nilai NLR lebih tinggi pada kelompok luaran meninggal. Hasil analisis tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR dengan luaran pasien sepsis (p >0,05). Kesimpulan: Tidak terdapat perbedaan yang signifikan antara Leukosit dan NLR terhadap luaran pasien sepsis. Kata Kunci: Biomarker, Leukosit, Mortalitas, NLR, Sepsis
Perbandingan Jumlah Koloni Bakteri pada Pasien Fraktur Terbuka Pre-operasi dan Post-operasi Miftahul Jannah; Maria Estela Karolina; Nindya Aryanty; Lipinwati; Mirna Marhami Iskandar
Journal of Medical Studies Vol. 4 No. 1 (2024): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v4i1.32090

Abstract

ABSTRACT Background: Open fracture is a structural break in the continuity of bone tissue which can relate to the environment of the body that is susceptible to infection. The World Health Organization (WHO) explains that surgical wound infections are infections that occur within 30 days postoperatively. This study aims to compare the number of bacterial colonies in pre and postoperative open fracture patients. Method: This research is a prospective observational analytic with quantitative methods. Sampling was taken by taking pre and postoperative wound swabs of open fracture patients and counting the number of bacterial colonies. Results: The study sample consisted of 23 samples, consisting of men (100%), the largest age range between 20-60 years (73.9%), the most common trauma mechanism was traffic accidents (52.2%) and the most location was the lower extremities (56,4%). The incidence of infection found 20 patients (87%) had preoperative infections and all patients (100%) had no infections 3 days postoperatively. The results of the Wilcoxon test showed a significant difference between the number of bacterial colonies in pre and postoperative open fracture patients (p<0.05). Conclusion: There were differences in the number of bacterial colonies in preoperative and postoperative open fracture patients. Keywords: Bacterial colony count, Open fractures, Surgery ABSTRAK Latar belakang: Fraktur terbuka merupakan terputusnya kontinuitas jaringan tulang secara struktural yang dapat berhubungan dengan lingkungan luar tubuh sehingga rentan terjadi infeksi. World Health Organization (WHO) menjelaskan bahwa infeksi luka operasi adalah infeksi yang terjadi dalam 30 hari paska operasi. Tujuan penelitian ini adalah untuk membandingkan jumlah koloni bakteri pada pasien fraktur terbuka pre dan post operasi. Metode: Penelitian ini merupakan penelitian analitik observasional pendekatan prospektif dengan metode kuantitatif. Pengambilan sampel dengan mengambil swab luka pasien fraktur terbuka pre dan post operasi dan dilakukan penghitungan jumlah koloni bakterinya. Hasil: Sampel penelitian ini berjumlah 23 sampel, terdiri atas laki-laki (100%), rentang usia terbanyak adalah 20-60 tahun (73,9%), mekanisme trauma tersering adalah kecelakaan lalu lintas (52,2%), dan lokasi terbanyak adalah ekstremitas bawah (56,4%). Kejadian infeksi dari total sampel penelitian didapatkan 20 pasien (87%) mengalami infeksi pre operasi dan seluruh pasien (100%) tidak mengalami infeksi 3 hari post operasi. Hasil uji Wilcoxon menunjukkan adanya perbedaaan yang signifikan antara jumlah koloni bakteri pasien fraktur terbuka pre dan post operasi (p<0,05). Kesimpulan: Terdapat perbedaan jumlah koloni bakteri pada pasien fraktur terbuka pre operasi dan post operasi. Kata kunci: Jumlah koloni bakteri, Fraktur terbuka, Operasi
Relationship Between the Use of Boots and the Incidence of Tinea Pedis in Motor Vehicle Wash Employees in Jambi City Hasibuan, Fitra Husni Mubarak; Hanina; Aurora, Wahyu Indah Dewi; Lipinwati; Maharani, Citra
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40683

Abstract

Background: Tinea pedis is a fungal infection of the skin of feet characterized by peeling skin, itching and watery skin. Risk factors for this disease are working in wet places and wearing closed shoes for a long time such as motor vehicle wash service workers. The purpose of this study was to determine the relationship between the use of boots and the incidence of tinea pedis in motor vehicle wash employees in Jambi City. Objective: This study aims to determine the relationship between the use of boots with the incidence of tinea pedis in motorbike wash employees in Jambi City Methods: This quantitative analytical research type with a crosssectional method The research sample was motor vehicle wash employees in Jambi City. The sampling technique used the cluster sampling method, researchers selected groups in each sub-district in Jambi City according to the research criteria as many as 96 samples. Data were obtained using questionnaires, physical examinations and KOH examinations. The data that had been obtained were then processed by computerization using the SPSS application. Results: In this study, it was found that there was a significant relationship between length of work and the incidence of tinea pedis, length of use of boots with the incidence of tinea pedis and foot hygiene with the incidence of tinea pedis. Representatively p-value less than 0.005 (p=0.016) (p=0.000) (p=0.000). Conclusion: The longer working in a humid place, the longer using boots, and the worse foot hygiene a person has increases the risk of getting tinea pedis
The The Correlation of Neutrophil-to-Lymphocyte Ratio with LupusQoL in Systemic Lupus Erythematosus Patients Mahrunnisa Rienti Sepestian; Lipinwati; Dewi, Hasna; Hanina; Nyimas Natasha Ayu Shafira
Journal of Medical Studies Vol. 5 No. 2 (2025): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v5i2.40840

Abstract

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations depending on disease activity. Clinical manifestations, disease activity, and side effects of treatment can affect quality of life. The LupusQoL questionnaire assesses the disease's impact on eight quality of life domains. The Neutrophil-to-Lymphocyte Ratio (NLR) is an inflammatory biomarker that correlates with SLE disease activity. Objective: This research aims to determine the correlation between NLR and various domains of the LupusQoL questionnaire in SLE patients. Methods: This observational analytic study used purposive sampling, involving 32 SLE patients treated at Raden Mattaher Hospital, Jambi, in 2024. NLR was obtained from blood counts performed within the last 4 weeks, and HRQOL was measured using the LupusQoL questionnaire. Data were analyzed using Pearson correlation. Result: The mean NLR was 6.50 (1.3–29.43). LupusQoL showed the lowest score in fatigue (58.85). Pearson analysis revealed a moderate inverse correlation between NLR and the planning domain of LupusQoL (p= 0,022). NLR shows no statistically significant correlation with physical health, pain, intimacy, burden to others, emotional health, body image, or fatigue in SLE patients, as p-values >0.05. Conclusion: Higher NLR is correlated with lower planning domain HRQoL in SLE patients and vice versa.
Co-Authors Ahmad Syauqy Ahmad Syauqy Aidil Rahmat Ilham Amatullah, Afifah Armaidi Darmawan Aromatika L ATTIYA ISTARINI Attiya Istarini Attiya Istarini Baiti, MIftakhul Citra Maharani Denok Tri Hardiningsih dewi, hasna Efendy, Makruf Ekaputri, Tia Wida Elfrida, Solha Erny Kusdiyah Esa Indah Ayu, Esa Indah Fadillah, Tanty Fairuz Quzwain Fairuz, Fairuz Fitriyanti Fitriyanti Fitriyanti Hafizah Hafizah Hanina Hanina, Hanina Hasibuan, Fitra Husni Mubarak Hasna Dewi Hestiningtyas, Maya Humaryanto, Humaryanto Iskandar, Mirna Marhami Ivo Amrina Rasyada JMJ, Jurnal Juanda, Syahreza Hadi Juniati, Rianita Kusdiyah, Erni Lestari, Nur Afni Lisa, Mei Mahrunnisa Rienti Sepestian Mara Imam Taufik Siregar Maria Estela Karolina Maya Arini Hestiningtyas MIFTAHUL JANNAH Miftahurrahma Miranda, Melly Mirna Iskandar Natasia Ulfa, Regina Nindya Aryanty Nur Afni Lestari NURIYAH Nuriyah Nuriyah Nuriyah, Nuriyah Nyimas Natasha Ayu Shafira Patrick William Gading Permana, Oki Putri Sari Wulandari Quzwain, Fairuz Chatib Resty Hardianty Lestari Rhonaz Putra Agung Rita Halim Samsirun H Samsirun Halim Simanjuntak, Charles Apul Siregar, Mara Imam Taufiq Siska, meliana Sotianingsih Sotianingsih Sotianingsih, Sotianingsih Suzan, Raihanah Syofira, Novianti Tengku Arief Buana Perkasa Wahyu Indah Dewi Aurora Zikri, Rahmat