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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Tropical and Infectious Disease J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Jurnal Respirasi (JR) Jurnal Ilmiah Kesehatan Jurnal Layanan Masyarakat (Journal of Public Service) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology International Journal of Social Service and Research Jurnal Ilmiah Kesehatan (JIKA) Journal of Innovation Research and Knowledge Multidisciplinary Indonesian Center Journal Jurnal Widya Medika Folia Medica Indonesiana
Rebekah Setiabudi, Rebekah
Clinical Microbiology Specialist Program, Faculty Of Medicine, Universitas Airlangga − Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Religion Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in a Tertiary Hospital, Surabaya, Indonesia Utami, Mahrumi Dewi Tri; Wahyunitisari, Manik Retno; Mardiana, Nunuk; Setiabudi, Rebekah Juniati
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: • Most urinary tract infections are caused by Gram-negative bacteria with E. coli being the most common bacteria. • Antibiotics with the highest susceptibility for Gram-negative bacteria were ertapenem, meropenem, amikacin, and imipenem. • Antibiotics with the highest susceptibility for Gram-positive bacteria mainly were susceptible to chloramphenicol,streptomycin, vancomycin, rifampin, tigecycline, teicoplanin, and ampicillin. Abstract: Urinary tract infection (UTI) is one of the most common bacterial infections. Inappropriate antibiotic use for UTI treatment may lead to antibiotic resistance. This study aimed to provide an updated bacterial and antibiogram profile from urine specimens of patients diagnosed with UTI. This study was a retrospective study using urine culture and antibiotic susceptibility test results obtained from Clinical Microbiology Laboratory in a tertiary general hospital in Surabaya, Indonesia for a two-month period patients. Most aged more than and/or equal to 59 years, in both sexes. Gram-negative bacteria, particularly , was being the most between June to July 2019. There were 215 patients with significant urine culture results of 54.4% from Escherichia coli female bacteria were carbapenem antibiotics and amikacin, while teicoplanin and vancomycin were some antibiotics susceptible to gramcommon bacteria that caused UTI, followed by K. pneumoniae. Some antibiotics with the highest susceptibility to gram-negative positive bacteria. This study result indicated that there was an urge to conduct local antibiogram profile investigation due to the low susceptibilities shown in recent empirical therapy recommendations, such as trimethoprim sulfamethoxazole, fluoroquinolone, nitrofurantoin, and fosfomycin.
Triglycerides Level and Body Mass Index in Type 2 Diabetes Mellitus Patients with Tuberculosis in an Indonesian Tertiary Hospital Theresia Trishavena Yuanita Pramesty; Wahyunitisari, Manik Retno; Setiabudi, Rebekah J.; Yudhawati, Resti; Priyambodo, Djoko Agung
Current Internal Medicine Research and Practice Surabaya Journal Vol. 7 No. 1 (2026): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

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Introduction: Type 2 Diabetes Mellitus (T2DM) is a chronic disease that can cause metabolic disturbances, includingdyslipidemia, characterized by elevated triglyceride levels. Patients with T2DM are also at higher risk of developingtuberculosis (TB) due to compromised immune function. Body Mass Index (BMI), which reflects nutritional status, mayinfluence triglyceride levels. In several studies, increasing BMI was accompanied by an increase in triglycerides. This studyaims to analyze the relationship between triglyceride levels and BMI in T2DM patients with TB in Dr. Soetomo GeneralAcademic Hospital, Surabaya, Indonesia, from 2021 to 2022. Methods: This study utilized secondary data from patients diagnosed with T2DM and TB between 2021 and 2022,respectively. Inclusion criteria were patients with complete medical records, including age, gender, cholesterol andtriglyceride levels, height, and weight, with 83 patients meeting these criteria. Statistical analysis was performed with oneway ANOVA for continuous variables, the Kruskal-Wallis test for non-homogeneous data, chi-square for categoricalvariables, and Pearson correlation for variable relationships. A p-value < 0.05 was considered statistically significant. Results: Triglyceride levels increased across all BMI categories, with values of 143.48 (57.83) for underweight, 173.74(75.74) for normal weight, and 183.80 (98.61) for overweight. Additionally, the correlation between BMI and triglycerideswas not significant (p=0.83), suggesting no meaningful association between these two variables in this study. Conclusion: The absence of differences in triglyceride levels in each BMI group is possible due to the use of triglyceridesfor the formation of granuloma triglyceride synthesis in T2DM with TB.
CLINICAL PROFILE OF DRUG-RESISTANT TUBERCULOSIS (DR-TB) PATIENTS DURING THE COVID-19 PANDEMIC AT RSUD DR. SOETOMO (JANUARY 2021 - DECEMBER 2021) (TITLE) Valentina Alfianti Herdy Tamyn; Rebekah J. Setiabudi; Soedarsono; Ibrahim Syamsuri; Shofiuddin Al Mufid
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 3 No. 1 (2026): Vol. 3 No. 1 Edisi Januari 2026
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v3i1.1608

Abstract

The emergence of the COVID-19 pandemic in 2019 has had an impact on all aspects of life, particularly global health. Indonesia is one of the affected countries. The Indonesian government has responded to the conditions of this pandemic, one of which is by imposing access restrictions to prevent the pandemic from spreading. This policy indirectly affects the community's activities, including the utilization of existing healthcare services. Meanwhile, available data show that one of the major issues that the Indonesian state is still dealing with is its status as the third country with the greatest number of TB (Tuberculosis) cases in the world, with some of the TB cases being classified as Drug-Resistant Tuberculosis (DR-TB).
Edukasi Resistensi Antimikroba pada Siswa SMA: Upaya Membangun Kesadaran Penggunaan Antibiotik yang Bijak: Upaya Membangun Kesadaran Penggunaan Antibiotik yang Bijak Koendhori, Eko Budi; Dwi Endraswari, Pepy; Kusumaningrum, Deby; Mahmudatul Muna, Nafdzu; Juniastuti, Juniastuti; Wiqoyah, Nurul; Retno Wahyunitisari, Manik; J. Setiabudi, Rebekah; Wiwin Retnowati; Setiawan, Firman; Alimsardjono, Lindawati
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 10 No 3 (2025): Desember
Publisher : Politeknik Negeri Jember

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Latar Belakang: Resistensi antimikroba merupakan salah satu ancaman kesehatan global yang dapat meningkatkan angka kesakitan, kematian, dan biaya pelayanan kesehatan. Edukasi tentang penggunaan antibiotik yang bijak perlu diberikan sejak usia sekolah agar siswa dapat menjadi agen perubahan di masyarakat.Tujuan: Meningkatkan pengetahuan siswa SMA mengenai antibiotik dan resistensi antimikroba melalui edukasi interaktif.Metode: Kegiatan dilaksanakan pada 97 siswa SMA Al-Uswah Surabaya dengan metode seminar, diskusi, dan lomba media edukasi (video/poster). Evaluasi dilakukan melalui kuesioner pre-test dan post-test dengan 10 pertanyaan terkait antibiotik dan resistensi antimikroba. Analisis dilakukan dengan menghitung persentase jawaban benar dan peningkatan pengetahuan.Hasil: Rata-rata skor post-test meningkat dibandingkan pre-test. Peningkatan tertinggi pada pertanyaan mekanisme resistensi antibiotik (34,5%), terendah pada pemahaman dasar antibiotik (3,9%). Normalized gain (g=0,44) menunjukkan kategori peningkatan sedang.Kesimpulan: Edukasi interaktif efektif meningkatkan pemahaman siswa tentang resistensi antimikroba. Kegiatan serupa perlu dilanjutkan secara berkelanjutan dan diperluas ke sekolah lain.
Profile of Infection in Systemic Lupus Erythematosus Patients Undergoing Inpatient Care at the Department of Internal Medicine of an Indonesian Tertiary Hospital Nafila, Ifroh Nurdian; Awalia; Setiabudi, Rebekah J
Current Internal Medicine Research and Practice Surabaya Journal Vol. 7 No. 1 (2026): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

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Abstract

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by excessive immune system reactivation. This disruption weakens the body's defense mechanisms against infections. Over half of SLE patients experience infections that contribute to 25-50% of all deaths in these patients and are the leading cause of morbidity and mortality in SLE. This study aims to profile the incidence, type, etiology, and outcome of SLE patients with infections. Methods: A descriptive observational study used a cross-sectional approach to examine SLE patients with infectious manifestations. Samples were selected by total sampling from 234 medical records of SLE patients, with 115 patients who met the inclusion criteria (hospitalized at Internal Medicine, Dr. Soetomo Hospital, Surabaya, Indonesia). Exclusion criteria included patients without infectious manifestations. Data were collected using data collection sheets and analyzed univariately to show each variable's frequency distribution and percentage. Results: Of the 115 patients, 96 were female (83.5%), and 33% were aged 11-20. The most common infections were pneumonia (31.3%), upper respiratory tract infections (18.3%), and sepsis (12.2%). The pathogens included bacteria (52.2%), viruses (44.3%), fungi (2.6%), and parasites (0.9%). Outcomes included recovery (14.8%), improvement (51.3%), forced discharge (3.5%), and death (30.4%), with pneumonia (50%), sepsis (23.1%), and upper respiratory tract infections (15.5%) being the leading causes of death. Conclusion: The highest infection rates in SLE patients occur in young women (11-20 years) with pneumonia, upper respiratory infections, and sepsis, which significantly contribute to mortality. The infections are predominantly bacterial and viral infections
PROFIL KLINIS PASIEN DENGAN KOINFEKSI HIV DAN TB DI RSUD DR. SOETOMO PERIODE JANUARI 2021-DESEMBER 2022 Rafif Razan Abdillah; Rebekah Juniati Setiabudi; Musofa Rusli; Vitanata Arfijanto
Journal of Innovation Research and Knowledge Vol. 6 No. 2 (2026): Juli 2026
Publisher : Bajang Institute

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Abstract

Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the most common opportunistic infections and a leading cause of mortality among people living with Human Immunodeficiency Virus (HIV). TB infection accelerates the progression of HIV to Acquired Immunodeficiency Syndrome (AIDS), making early identification and appropriate management essential. This study aimed to describe the clinical profile of patients with HIV-TB coinfection treated at Dr. Soetomo Regional General Hospital, Surabaya, a national referral hospital, during January 2021–December 2022. Methods: This descriptive study employed a retrospective design using secondary medical record data. Samples were selected through consecutive sampling based on predetermined inclusion and exclusion criteria. Data were analyzed descriptively to characterize the demographic and clinical profiles of patients with HIV-TB coinfection. Results: A total of 34 patients met the study criteria. Most patients were aged 26–45 years (47.1%), male (71%), employed in the private sector (38.2%), and had completed senior high school education (58.3%). The majority developed TB within one year after being diagnosed with HIV (55.9%). The most frequently prescribed antiretroviral (ARV) regimen was Tenofovir (TDF) + Lamivudine (3TC) + Efavirenz (EFV) (58.8%). Conclusion: HIV-TB coinfection at Dr. Soetomo Regional General Hospital predominantly occurred within the first year following HIV diagnosis. The TDF+3TC+EFV regimen was the most commonly administered ARV treatment. These findings provide useful baseline information for improving early detection, clinical monitoring, and management strategies for patients with HIV-TB coinfection.
Co-Authors Achmad Ardianto Adhima, Fauziah Afif Hidayati Agung Dwi Wahyu Widodo Alimsardjono, Lindawati Anindita Rehana Arina Setyaningtyas Awalia Ayu Rahmanita Putri Soetrisno Ayurveda Zaynabila Heriqbaldi Azzahra, Safira Deby Kusumaningrum Dewi Setyowati Diah Mira Indramaya Didik Didik Handijatmo, Didik Dwiyanti Puspitasari, Dwiyanti Eko Budi Koendhori, Eko Budi Evy Ervianti Farah Meriana Fajrin Hammam Izza Rofiqi Hasan, Helmia Ibrahim Syamsuri Indiastuti, Danti Nur Juniastuti Juniastuti Khairunnida Rahma Laksmi Wulandari M. Kharis Khamdan M. Yulianto Listiawan Mahmudatul Muna, Nafdzu Mahrumi Dewi Tri Utami Manik R Wahyunitisari ManikRetno Wahyunitisari Mariska Nuriana Marsha Zahrani Maya Wardiana Musofa Rusli Nafila, Ifroh Nurdian Neurinda Permata Kusumastuti Ni Made Mertaniasih Nunuk Mardiana, Nunuk Nurul Wiqoyah, Nurul Pepy Dwi Endraswari, Pepy Dwi Prasanti, Siva Allysha Priyambodo, Djoko Agung Purwanto, Satiti Palupi Putri S Wulandari Rafif Razan Abdillah Rafly Bayu Surya Wardhana Rahma, Khairunnida Rahmadewi Rahmadewi Rehana, Anindita Resti Yudhawati Retno Asih Setyoningrum Retno Wahyunitisari, Manik Risky Vitria Prasetyo Rochmanti, Maftuchah Rochmanti Rossyanti, Lynda S. Soedarsono Sawitri Sawitri Setiawan, Firman Shofiuddin Al Mufid Silvia Sutandhio Sri Ratna Dwiningshih Suhintam Pusarawati Sulistiawati Sulistiawati Sulistiawati Sulistiawati Theresia Trishavena Yuanita Pramesty Titiek Sulistyowati Utami Meilanie Putri Utami, Mahrumi Dewi Tri Valentina Alfianti Herdy Tamyn Vitanata Arfijanto Wahyunitisari, Manik Retno Wardhany, Atiqah Nurul Warella, Juen Carla Wiwin Retnowati Yuri Widia, Yuri