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Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in a Tertiary Hospital, Surabaya, Indonesia Utami, Mahrumi Dewi Tri; Wahyunitisari, Manik Retno; Mardiana, Nunuk; Setiabudi, Rebekah Juniati
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Highlights: • Most urinary tract infections are caused by Gram-negative bacteria with E. coli being the most common bacteria. • Antibiotics with the highest susceptibility for Gram-negative bacteria were ertapenem, meropenem, amikacin, and imipenem. • Antibiotics with the highest susceptibility for Gram-positive bacteria mainly were susceptible to chloramphenicol,streptomycin, vancomycin, rifampin, tigecycline, teicoplanin, and ampicillin. Abstract: Urinary tract infection (UTI) is one of the most common bacterial infections. Inappropriate antibiotic use for UTI treatment may lead to antibiotic resistance. This study aimed to provide an updated bacterial and antibiogram profile from urine specimens of patients diagnosed with UTI. This study was a retrospective study using urine culture and antibiotic susceptibility test results obtained from Clinical Microbiology Laboratory in a tertiary general hospital in Surabaya, Indonesia for a two-month period patients. Most aged more than and/or equal to 59 years, in both sexes. Gram-negative bacteria, particularly , was being the most between June to July 2019. There were 215 patients with significant urine culture results of 54.4% from Escherichia coli female bacteria were carbapenem antibiotics and amikacin, while teicoplanin and vancomycin were some antibiotics susceptible to gramcommon bacteria that caused UTI, followed by K. pneumoniae. Some antibiotics with the highest susceptibility to gram-negative positive bacteria. This study result indicated that there was an urge to conduct local antibiogram profile investigation due to the low susceptibilities shown in recent empirical therapy recommendations, such as trimethoprim sulfamethoxazole, fluoroquinolone, nitrofurantoin, and fosfomycin.
Edukasi Resistensi Antimikroba pada Siswa SMA: Upaya Membangun Kesadaran Penggunaan Antibiotik yang Bijak: Upaya Membangun Kesadaran Penggunaan Antibiotik yang Bijak Koendhori, Eko Budi; Dwi Endraswari, Pepy; Kusumaningrum, Deby; Mahmudatul Muna, Nafdzu; Juniastuti, Juniastuti; Wiqoyah, Nurul; Retno Wahyunitisari, Manik; J. Setiabudi, Rebekah; Wiwin Retnowati; Setiawan, Firman; Alimsardjono, Lindawati
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 10 No 3 (2025): Desember
Publisher : Politeknik Negeri Jember

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Latar Belakang: Resistensi antimikroba merupakan salah satu ancaman kesehatan global yang dapat meningkatkan angka kesakitan, kematian, dan biaya pelayanan kesehatan. Edukasi tentang penggunaan antibiotik yang bijak perlu diberikan sejak usia sekolah agar siswa dapat menjadi agen perubahan di masyarakat.Tujuan: Meningkatkan pengetahuan siswa SMA mengenai antibiotik dan resistensi antimikroba melalui edukasi interaktif.Metode: Kegiatan dilaksanakan pada 97 siswa SMA Al-Uswah Surabaya dengan metode seminar, diskusi, dan lomba media edukasi (video/poster). Evaluasi dilakukan melalui kuesioner pre-test dan post-test dengan 10 pertanyaan terkait antibiotik dan resistensi antimikroba. Analisis dilakukan dengan menghitung persentase jawaban benar dan peningkatan pengetahuan.Hasil: Rata-rata skor post-test meningkat dibandingkan pre-test. Peningkatan tertinggi pada pertanyaan mekanisme resistensi antibiotik (34,5%), terendah pada pemahaman dasar antibiotik (3,9%). Normalized gain (g=0,44) menunjukkan kategori peningkatan sedang.Kesimpulan: Edukasi interaktif efektif meningkatkan pemahaman siswa tentang resistensi antimikroba. Kegiatan serupa perlu dilanjutkan secara berkelanjutan dan diperluas ke sekolah lain.
PROFIL KLINIS PASIEN DENGAN KOINFEKSI HIV DAN TB DI RSUD DR. SOETOMO PERIODE JANUARI 2021-DESEMBER 2022 Rafif Razan Abdillah; Rebekah Juniati Setiabudi; Musofa Rusli; Vitanata Arfijanto
Journal of Innovation Research and Knowledge Vol. 6 No. 2 (2026): Juli 2026
Publisher : Bajang Institute

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Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the most common opportunistic infections and a leading cause of mortality among people living with Human Immunodeficiency Virus (HIV). TB infection accelerates the progression of HIV to Acquired Immunodeficiency Syndrome (AIDS), making early identification and appropriate management essential. This study aimed to describe the clinical profile of patients with HIV-TB coinfection treated at Dr. Soetomo Regional General Hospital, Surabaya, a national referral hospital, during January 2021–December 2022. Methods: This descriptive study employed a retrospective design using secondary medical record data. Samples were selected through consecutive sampling based on predetermined inclusion and exclusion criteria. Data were analyzed descriptively to characterize the demographic and clinical profiles of patients with HIV-TB coinfection. Results: A total of 34 patients met the study criteria. Most patients were aged 26–45 years (47.1%), male (71%), employed in the private sector (38.2%), and had completed senior high school education (58.3%). The majority developed TB within one year after being diagnosed with HIV (55.9%). The most frequently prescribed antiretroviral (ARV) regimen was Tenofovir (TDF) + Lamivudine (3TC) + Efavirenz (EFV) (58.8%). Conclusion: HIV-TB coinfection at Dr. Soetomo Regional General Hospital predominantly occurred within the first year following HIV diagnosis. The TDF+3TC+EFV regimen was the most commonly administered ARV treatment. These findings provide useful baseline information for improving early detection, clinical monitoring, and management strategies for patients with HIV-TB coinfection.