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All Journal Current Biochemistry Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan MATRIK : Jurnal Manajemen, Teknik Informatika, dan Rekayasa Komputer Jurnal Pengabdian Magister Pendidikan IPA JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Kolaboratif Sains Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Jurnal Medical Laboratory Jurnal Ilmiah Pengabdian dan Inovasi Jurnal Multidisiplin Sahombu PCJN Pharmaceutical and Clinical Journal of Nusantara BIOCITY: Journal of Pharmacy Bioscience and Clinical Community Pengabdian Kepada Masyarakat Bidang Teknologi dan Sistem Informasi Jurnal Wicara Desa Indonesian Journal of Health Research Innovation
Nurul Indriani
Universitas Bumigora, Mataram, Indonesia
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Journal : Jurnal Multidisiplin Sahombu

 1 
Formulation and Evaluation Testing of Cream Nail Polish from Impatiens balsamina L. Seed Powder Sahra, Baiq Yatmi El; Indriani, Nurul; Sofya, Sri Winarni
Jurnal Multidisiplin Sahombu Vol. 5 No. 5 (2025): Jurnal Multidisiplin Sahombu, July - August (2025)
Publisher : Sean Institute

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Cosmetics based on natural ingredients are increasingly favoured due to their perceived safety and environmental friendliness. One traditional plant with potential for development is water cress (Impatiens balsamina L.), which has long been utilised as a traditional medicine. This research aims to design a formulation and evaluate the preparation of cream nail polish with the additional component of water cress powder. This plant is known to contain flavonoids such as kaempferol and quercetin, which are beneficial for maintaining nail health. The study employed an experimental method with four formulations of nail polish, namely F0 (without powder), F1 (0.3%), F2 (0.5%), and F3 (0.75%). The preparation process involved the use of additional materials such as PVP, titanium dioxide, castor oil, methylparaben, and alcohol. Evaluation included organoleptic tests, homogeneity, pH, adhesion, spreadability, and hedonic testing involving 30 adolescent to adult panellists. The results indicated that all formulations exhibited good physical stability, pH values in accordance with standards, and high levels of preference, particularly for formulation F3 in terms of texture and final appearance. The addition of water cress seed powder provides additional benefits for nail moisture and protection. Thus, water cress seed powder can be considered as an alternative ingredient in the production of safer and more environmentally friendly cosmetic products. This research is expected to open new opportunities in the development of herbal-based cosmetics
Effectiveness Test of Ketapang Leaf Extract (Terminalia Catappa L.) as a Hepatoprotective Agent in Mice (Mus musculus) Induced by Acetaminophen Anjani, Desak Sri Ayu; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Jurnal Multidisiplin Sahombu Vol. 5 No. 5 (2025): Jurnal Multidisiplin Sahombu, July - August (2025)
Publisher : Sean Institute

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Drug-induced liver injury (DILI) is a leading cause of acute liver failure, with acetaminophen being the most frequent etiological agent. Overdose induces formation of the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI), resulting in glutathione depletion, oxidative stress, and hepatocellular necrosis. This study aimed to evaluate the hepatoprotective effect of ethanolic extract of Terminalia catappa L. leaves in male mice (Mus musculus) with acetaminophen-induced acute liver injury. A post-test only control group design was employed using 20 mice divided into five groups: negative control (Na-CMC), positive control (N-acetylcysteine), and three treatment groups receiving T. catappa extract at doses of 200, 400, and 600 mg/kg BW. Acetaminophen was administered intraperitoneally at 500 mg/kg BW. Serum SGPT and SGOT levels were quantified spectrophotometrically, and phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids. Extract administration significantly (p < 0.05) reduced SGPT and SGOT levels compared to the negative control, with a clear dose-dependent trend; the 600 mg/kg BW group achieved biochemical parameters approaching those of the N-acetylcysteine group. The hepatoprotective effect is likely mediated by flavonoid-driven antioxidant and anti-inflammatory mechanisms. These findings indicate that T. catappa extract is a promising, safe, and cost-effective plant-based hepatoprotective agent, meriting further investigation toward clinical application as an adjunct therapy for drug-induced hepatotoxicity
Co-Authors Adriyan Suhada Aini, Niza Husnul Aini, Zahratul Ajeng Dian Pertiwi, Ajeng Dian Aji Kresnapati, Nyoman Bagus Anam, M Khairul Anisah, Nur Anjani, Desak Sri Ayu Apriani , Nurul Aulia Aprilia, Dwi Ayu Awang, Kevin Aditya Agusto Ayudia Cipta Khairani Azizah, Nur Shafa Azkia, Tina Imro’atun Baiq Yulia Hasni Pratiwi Bq Sari Hidayatullah Dinda Febriani Eka Nurul Qomaliyah Estiana Fardani, Roushandy Asri Farida Ariani Fitri Apriliany, Fitri Hafiz, Lalu Muhamad Fajri Hendri Yogi Pratama I Made Suartika Ibrahim, Muhammad Rivani Idham Halid Inayati, Rizqa Islamiyati, Ricka Ispaniah Jannaturroyani Jundillah, Muhammad Labib Kresnapati, I Nyoman Bagus Aji Lalu Zulkifli M. Irpan Siswandi Mia Ariasti Mileniaputri, Ni Putu Rainita Muchsin, Lalu Busyairi Mudawil Qulub Muhamad Azwar Muhamad Azwar, Muhamad Muhamad Irham, Muhamad Muhammad Eka Putra Ramandha Muhsin, Lalu Busyairi Ni Nyoman Ariwidiani Novianty, Wanda Nur Anisah Nurfajrin Aliyatri Paturrahmi, Wilda Marta Pauzan Pauzan, Pauzan Ramadhani, Muhammad Wisda Pradja Ratulangi, Wulan Ratia Rizky Tri Septiawan Rizqa Inayati Rohma, Atika Rosnalia Widyan Sahra, Baiq Yatmi El Satria Wirananda, I Nengah Sekar Ningrat, Lalu Nune Sofya, Sri Winarni Syahria Ulya, Tuhfatul Utami, Evi Fatmi Utami, Nadia Fitri Warsi Warsi Warsi Warsi Widani Darma Isasih Yodisya, Raihan Yodita, Zahrawana Putri