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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL FARMASIMED (JFM) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Buana Farma Jurnal Abdimas Bina Bangsa Jurnal Abdimas Kartika Wijayakusuma Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Jurnal Sains dan Kesehatan Jurnal Kesehatan Masyarakat
Faizal Hermanto
Department Of Pharmacology And Toxicology, Faculty Of Pharmacy, Universitas Jenderal Achmad Yani, Cimahi, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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POTENSI RESVERATROL DALAM MENGURANGI KEPARAHAN MALARIA SEREBRAL PADA MENCIT YANG TERINFEKSI Plasmodium berghei ANKA Faizal Hermanto; Puspa Sari Dewi; Fahmy Ahsanul Haq; Nur Melsandy
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.842

Abstract

Malaria serebral (MS) adalah komplikasi neurologis yang parah dari infeksi Plasmodium falciparum menyebabkan ensefalopati dan bertanggung jawab atas sebagian besar kematian terkait malaria secara global. Tujuan dari penelitian ini adalah mengevaluasi potensi resveratrol dalam mengurangi keparahan malaria serebral pada mencit yang terinfeksi Plasmodium berghei ANKA. Mencit dikelompokkan menjadi beberapa kelompok yaitu kelompok normal (tidak terinfeksi), sedangkan mencit yang terinfeksi P. berghei dan menunjukkan gejala neurologis malaria serebral kemudian dikelompokan menjadi kelompok kontrol; klorokuin 20 mg/kg; resveratrol dosis 25, 50, dan 100 mg/kg. Parameter pengamatan meliputi parasitemia, gejala neurologis, indeks otak, dan evaluasi integritas sawar darah otak. Hasil menunjukkan setelah pemberian resveratrol berbagai dosis terjadi hambatan pertumbuhan parasit, penurunan gejala neurologis, penurunan indeks otak, dan mengurangi kerusakan sawar darah otak akibat infeksi P. berghei dibandingkan dengan kelompok kontrol. Kesimpulan dari penelitian ini adalah resveratrol dapat mengurangi keparahan malaria serebral pada mencit yang terinfeksi P. berghei ANKA. Kata kunci : malaria serebral, Plasmodium berghei, Resveratrol.
PENILAIAN RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN USIA 1-5 TAHUN DENGAN INFEKSI SALURAN PERNAPASAN AKUT (ISPA) DI PUSKESMAS CIMAHI TENGAH Sri Wahyuningsih; Faizal Hermanto; Andreanus A Soemardji; Riza Amelia; Yuliana Agustin
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1022

Abstract

Acute Respiratory Infection (ARI) is a disease that commonly occurs in children aged 1–5 years. Irrational use of antibiotics can cause bacterial resistance and unwanted side effects. This study aims to assess the rationality of antibiotic use in ISPA patients aged 1–5 years at the Central Cimahi Health Center in January–December 2022. The Central Cimahi Health Center conducted this descriptive study. This involves collecting retrospective prescription data from individuals aged 1–5 years throughout the period from January 2022 to December 2022. Data collection uses a saturated sampling method, where the total population is 526 prescriptions and prescriptions that do not meet the inclusion criteria and duplicates are 469 prescriptions, resulting in a total sample size of This research analyzed 56 recipes, both quantitatively and qualitatively. The evaluation of rationality includes the criteria for the right indication, the right drug, the right patient, and the right dose. The results show that the highest ARI characteristics are at the age of one year, namely 27% and the highest gender occurs in boys at 55%. The rationality of antibiotic use based on the criteria of right indication, right drug, right patient, and right dose shows a percentage of 100%. The Central Cimahi Community Health Center evaluates the rationality of antibiotic use in ISPA patients aged 1-5 years as rational
PENGARUH EDUKASI NUTRISI KEPADA IBU OBESITAS DENGAN ANAK STUNTING TERHADAP PENURUNAN BEBAN GANDA MALNUTRISI DI KECAMATAN SERANG BARU-KABUPATEN BEKASI Arifianti Essen, Amanda; Bambang Sutjiatmo, Afifah; Hermanto, Faizal
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 9 No 1 (2024): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v9i1.6815

Abstract

The double burden of malnutrition (obese mothers with stunted children) has become an important focus in the field of public health both in Indonesia and the world. Serang Baru District, Bekasi Regency, is one of the areas in Indonesia that has a significant prevalence of stunting and obesity. This study aims to determine the effectiveness of nutritional education interventions for obese mothers of stunted children on changes in the status of the double burden of malnutrition in the household. The research began with collecting sociodemographic, anthropometric and food intake data for the past 2x24 hours. Respondents who met the inclusion criteria were then given a face-to-face nutrition education intervention every week for 3 months. In the third month, all respondents had their data collected again in the form of anthropometric data and food intake data. The results of the study showed that after the nutritional education intervention was carried out there was a change in the child's HAZ score from -2.87 ± 0.56 to -2.61 ± 0.62, while the mother's BMI was originally 32.52 ± 2.48 to 31.72 ± 2.16 which was significantly different when compared to before the intervention (P<0.05). It can be concluded that nutrition education interventions can reduce the double burden of malnutrition in Serang Baru District, Bekasi Regency.
Efek Iritasi Sabun Mandi Batang Mengandung Susu Produk Usaha Kecil Menengah di Kota Cimahi Vikasari, Suci Nar; Hermanto, Faizal; Simatupang, Elivas; Sutjiatmo, Afifah Bambang; Sutarna, Titta Hartyana; Puspadewi, Ririn; Rachmawan, Lucky; Haq, Fahmy Ahsanul
Jurnal Kefarmasian Indonesia VOLUME 10, NOMOR 2, AGUSTUS 2020
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v10i2.2592

Abstract

One of the ways to increase profit in small and medium business (UKM) in Cimahi is by diversifying its products, through manufacturing of bar soap derived from cow's milk from UKM. The requirement of bath soap is proper acidity (pH) level, otherwise it will make the skin dry, itchy or even increase irritation. Therefore, this in vivo non-clinical irritation evaluation is conducted to evaluate the effects of bar soap produced by UKM in Cimahi according to the guidelines in rat test animals. The animals is divided into five groups and exposed to soap for four hours. Five soap samples is obtained from UKM in Cipageran area, Cimahi. Observations is made at the hours of 1, 4, 24, 48, and 72 hours after exposure and is continued for 14 days. The measured parameters is erythema and edema, and the primary irritation index. The results showed that bar soap containing cow milk produced by UKM in Cimahi did not cause erythema and edema. Primary irritation index of all bath soap samples was 0.0 . It can be concluded that soap bars containing cow's milk produced by Cimahi City UKM including into the category of very mild irritation (negligigle).
REVIEW: INSTRUMEN KUESIONER PADA PASIEN DIABETES MELITUS Putra , Erwin Ekadharma; Hermanto, Faizal; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1113

Abstract

Diabetes mellitus (DM) is a chronic disease with increasing prevalence worldwide, posing major challenges in patient management and monitoring. Questionnaire instruments are an important tool in DM patient evaluation because they allow systematic and measurable data collection regarding various aspects of the disease, including quality of life, self-management, and perceptions of care. This review article provides a comprehensive overview of various questionnaire instruments used for DM patient evaluation, interpretation of questionnaire results, and grouping based on categories. The review results indicate that the selection of an appropriate instrument must take into account the specific context of the patient population and the evaluation goals. Additionally, we group the evaluation instruments into several categories, including the patient's level of knowledge, compliance with treatment, severity of symptoms, fear of needles, mental condition, and improvement in the patient's quality of life. The conclusion of this article emphasizes the importance of questionnaires in DM management, as well as the need for further research to develop more comprehensive and responsive instruments. Questionnaire instruments, when selected and used appropriately, can improve clinical decision-making and the quality of care provided to DM patients.
KAJIAN INTERAKSI OBAT PASIEN DIABETES DI BEBERAPA RUMAH SAKIT DI INDONESIA Aeni, Siti Nur; Sukandar, Elin Yulinah; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1123

Abstract

Lebih dari 451 juta orang di seluruh dunia pada tahun 2017 diperkirakan menderita diabetes, suatu kelainan metabolik yang umum, dan diperkirakan akan meningkat menjadi 693 juta orang pada tahun 2045, atau 49,7% dari populasi orang dewasa (IDF Diabetes Atlas). Diabetes merupakan penyakit kronis yang seringkali memerlukan penggunaan kombinasi obat-obatan, sehingga meningkatkan risiko terjadinya interaksi obat. Tujuan dari penelitian ini adalah untuk menganalisis kemungkinan terjadinya interaksi obat potensial pada pasien diabetes melitus yang pernah berkunjung ke beberapa rumah sakit di Indonesia antara tahun 2014 dan 2024. Penelusuran pustaka dilakukan pada basis data Google Scholar, Pubmed dan jurnal-jurnal lainnya. Kriteria inklusi untuk publikasi artikel yang dipublikasikan selama dekade terakhir, artikel yang dipilih harus mengamati kasus-kasus interaksi obat pada pasien diabetes di rumah sakit. Penelusuran pustaka menghasilkan 10 jurnal yang relevan dan memenuhi kriteria. Hasil penelitian menyajikan potensi interaksi obat diabetes dengan berbagai obat lain berdasarkan mekanisme kerja, efek yang ditimbulkan, klasifikasi dan tingkat keparahan serta solusi yang ditampilkan. Obat diabetes yang paling banyak digunakan adalah Glimepirid dari golongan sulfonil urea. Studi interaksi obat sebagian besar bekerja secara farmakodinamik dengan tingkat keparahan sedang. Pentingnya pemantauan dan pengelolaan interaksi obat untuk meningkatkan efektivitas pengobatan dan keamanan pasien diabetes
REVIEW ARTIKEL: PENINGKATAN KELARUTAN SENYAWA OBAT ANTIMALARIA MENGGUNAKAN METODE MODIFIKASI KO-KRISTAL Hasna; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1134

Abstract

Malaria is an infectious disease caused by the Plasmodium parasite that infects humans through the bite of female Anopheles mosquitoes. Most antimalarial drugs have limitations in terms of solubility. Drug solubility is a very important parameter that determines the effectiveness of the drug, with good drug solubility, the drug can achieve optimal bioavailability and pharmacological effects, based on this, efforts are needed to overcome these problems in order to provide effective and efficient therapy to patients using existing antimalarial drugs that have been modified in their physicochemical properties so that their solubility increases. The purpose of this study was to review various studies that used the co-crystal modification method to increase the solubility of antimalarial drug compounds. This study was designed using the Narrative Review method, article searches were carried out using two databases, namely Google Scholar and PubMed, with the keywords "Co-crystal" OR "Antimalaria". In this study, 7 articles were found that met the inclusion and exclusion criteria. The selected articles are articles that discuss antimalarial drugs (artesunate, artemisinin, pyrimethamine) developed by the co-crystal method which experienced a multi-fold increase in solubility compared to its pure preparation. The co-crystal method can be a solubility enhancing solution for antimalarial drugs that have low solubility in water, increasing the solubility of antimalarial drugs causes the bioavailability of the drug to increase, so that the drug can provide good therapeutic effects.
REVIEW : ANALISIS PENGGUNAAN ANTIBIOTIK PROFILAKSIS PADA PASIEN PASCA BEDAH SESAR DI BEBERAPA RUMAH SAKIT DI INDONESIA Shalsabina, Vina; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1136

Abstract

Caesarean section shows an increase from year to year. The number of cesarean births every year also has an impact on the increase in post-surgical complications. The purpose of this article is to examine the effectiveness of the use of prophylactic antibiotics in patients after caesarean section. A systematic review of articles and publications published in the year 2014 to 2024 used 9 articles and used the search keyword, which is prophylactic antibiotics after caesarean section. The description of the use of prophylactic antibiotics that was seen includes the type, time of administration, method of administration, duration of treatment and dose of antibiotics, compared to the main guidelines of basic treatment of pharmacology and therapy according to Goodman & Gilman. It can be concluded that the most widely used antibiotics are the third generation cephalosporins, namely ceftriaxone and cefotaxime. These antibiotics are broad-spectrum, and target gram positive and gram negative bacteria, and are commonly used as prophylactic antibiotics in caesarean section patients.
REVIEW: POTENSI KETIDAKTEPATAN PENGGUNAAN OBAT PADA PASIEN GERIATRI DI BEBERAPA RUMAH SAKIT DI INDONESIA Pratama, Gumilar; Wahyuningsih, Sri; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1144

Abstract

Inappropriate medication use in geriatric patients, particularly related to Potentially Inappropriate Medications (PIMs), is a major concern in elderly healthcare management. This study aims to explore the prevalence and types of PIMs found in several hospitals in Indonesia. A narrative review method was employed, with journal data searched using the query: “Potentially Inappropriate Medications” OR “Potentially Inappropriate Prescribing”, “identification of PIMs”, “evaluation of PIMs”, “Beers Criteria” OR “Beers Criteria”, “STOPP Criteria”, “PRISCUS PIMs” in Google Scholar, Garuda, and PubMed databases. Articles selected met the inclusion criteria, including national and international journals published within the last 10 years and available in full text. The results showed that the prevalence of PIMs in a hospital in Semarang was 487 medication items, with sodium diclofenac being the most frequently found medication (12.96%). At RSUD Arjawinangun, the occurrence of PIMs reached 56.82%, with furosemide being the most dominant medication (22.73%). A study in Jakarta showed that prescription review by pharmacists successfully reduced the occurrence of PIMs to 18.89%. Inappropriate medication use in geriatric patients remains high, and it is essential to improve patient education and enhance collaboration between pharmacists and doctors to reduce PIMs risks. The use of Beers, STOPP, and PRISCUS criteria can help assess and prevent PIMs in geriatric patients.
REVIEW: GAMBARAN TINGKAT KESALAHAN PENGOBATAN PADA BEBERAPA RUMAH SAKIT DI INDONESIA Adiningsih, Martha; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1148

Abstract

A medication error is any preventable event that can cause or result in inappropriate medication use or harm to the patient. Medication errors can occur in several phases or stages, namely prescribing errors, errors in translating prescriptions, errors in preparing and dispensing drugs, and errors in administering drugs. The aim of this article is to review and identify various levels of medication errors in several hospitals in Indonesia which are obtained from the percentage of medication errors. Based on a literature review conducted on 10 journals, article searches were carried out using two databases, namely Google Schollar and PubMed, the results obtained were that the most common medication errors occurring in several hospitals in Indonesia were the prescribing phase with a total distribution of levels of 7, then dispensing with a count of 2 and copying with a count of 1. Although medication errors remain a major challenge, with appropriate improvement efforts, patient safety in hospitals can be significantly improved)
Co-Authors Achmad Zainuddin Ade Kania Ningsih, Ade Kania Adiningsih, Martha Afifah Bambang Sutjiatmo, Afifah Bambang Ahsanul Haq, Fahmi Akhirul Kahfi Syam Andreanus A Soemardji Ari Sri Windyaswari, Ari Sri Arif Rahman Hakim Arifianti Essen, Amanda Choirunissa, Anna Diah Lia Aulifa Elin Yulinah Sukandar Euis Julaeha Fahrauk Faramayuda, Fahrauk Fani Wahyuni, Fani Febrinella, Catellya Fikri Alatas Gusdilla, Windy Haq, Fahmy Ahsanul Hartyana Sutarna, Titta Hasna Hestiary Ratih Lilis Siti Aisyah, Lilis Siti Linda Purnamawati Suherman Lutfi, Mutiara Hadi Mochammad Luthfi Pramukti, Mochammad Luthfi Muchtaridi Muchtaridi Nur Melsandy Pratama, Gumilar Puspa Sari Dewi Putra , Erwin Ekadharma Rachmawan, Lucky Rachmawan, R. Lucky Rachmawati, Ita Rani Sugandi, Rani Refiani , Aqila Ririn Puspadewi, Ririn Riskia Putri Peratiwi, Riskia Putri Riza Amelia Riza Amelia Rizwan, Akmal Rochmah, Nur Syifa Sembiring, Rinawati Shalsabina, Vina Simatupang, Elivas Siti Nur Aeni, Siti Nur Soraya Riyanti, Soraya Sri Wahyuningsih Sri Wahyuningsih Suci Nar Vikasari, Suci Nar SURYANI Susy Tjahjani Tati Herlina Tri Reksa Saputra, Tri Reksa Unang Supratman Yenny Febriani Yun, Yenny Febriani Yuliana Agustin Zamzami Adnan, Risky