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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL FARMASIMED (JFM) Pharmacoscript Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Buana Farma Jurnal Abdimas Bina Bangsa Jurnal Abdimas Kartika Wijayakusuma Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Jurnal Sains dan Kesehatan Jurnal Kesehatan Masyarakat Journal of Pharmascience
Faizal Hermanto
Department Of Pharmacology And Toxicology, Faculty Of Pharmacy, Universitas Jenderal Achmad Yani, Cimahi, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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The Rationality of Drug Therapy in Pulmonary Anti-Tuberculosis Patients at Puskesmas Cimahi Tengah Purnamawati Suherman, Linda; Abdul Rozzaaq, Muhammad; Ramdani, Robby; Amelia, Riza; Hermanto, Faizal; Septiani, Vina; Nurul Islamiyah, Alfi
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 3 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i32025.382-390

Abstract

Background: Tuberculosis (TB) is a significant global health challenge in Indonesia. The rational use of anti-TB drugs is essential for treatment success and for preventing drug resistance in patients with TB. Objectives: This study aimed to evaluate the rationality of anti-TB drug use in patients with pulmonary TB at the Cimahi Tengah Public Health Center (Puskemas Cimahi Tengah). Methods: This research employed a descriptive method with a retrospective approach based on observational data from the Tuberculosis Information System (SITB) between January and December 2023. Samples were selected using purposive sampling based on the predefined inclusion and exclusion criteria. Results: The results showed that All patients (100%) received treatment according to the national guidelines and WHO recommendations, including the HRZE regimen (rifampicin, isoniazid, pyrazinamide, and ethambutol). The accuracy of indication, drug selection, dosage, and administration intervals also reached 100%, demonstrating adherence to the clinical standards. Conclusion: Anti-TB drug use at the Cimahi Tengah Public Health Center complies with established treatment standards, ensuring treatment effectiveness and contributing to optimal patient outcomes.
ANALISIS TINGKAT KEPUASAN PASIEN JKN TERHADAP PELAYANAN KEFARMASIAN MENGGUNAKAN METODE SERVQUAL DAN IMPORTANCE PERFORMANCE ANALYSIS (IPA) DI SALAH SATU PUSKESMAS KOTA CIMAHI Robby, Ramdani; Puspa Sari , Dewi; Alfi Nurul, Islamiyah; Faizal, Hermanto; Imeldha R Pramesty , Putri
Pharmacoscript Vol. 9 No. 1 (2026): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v9i1.2348

Abstract

Kebijakan pelayanan berjenjang dalam program Jaminan Kesehatan Nasional (JKN) menyebabkan meningkatnya beban pelayanan di Fasilitas Kesehatan Tingkat Pertama (FKTP) seperti Puskesmas, sehingga berpotensi menurunkan mutu pelayanan, termasuk pelayanan kefarmasian. Kondisi ini dapat berdampak pada kepuasan pasien, yang merupakan indikator penting kualitas pelayanan. Pelayanan ini bertujuan untuk menganalisis tingkat kepuasan pasien JKN terhadap pelayanan kefarmasian di salah satu Puskesmas Kota Cimahi, serta menentukan prioritas perbaikan dan atribut layanan yang perlu dipertahankan menggunakan metode Service Quality (ServQual) dan Importance Performance Analysis (IPA). Penelitian ini menggunakan desain deskriptif cross sectional dengan metode purposive sampling terhadap 378 responden yang memenuhi kriteria inklusi. Data diperoleh melalui kuesioner yang teruji validitas dan reliabilitasnya, kemudian dianalisis menggunakan SPSS Statistic 30. Hasil penelitian menunjukkan bahwa seluruh analisis ServQual-IPA memiliki nilai gap negatif, dengan urutan kesenjangan terbesar pada dimensi Jaminan (-0,21;0,94), Empati (-0,19;0,95), Kehandalan (-0,12;0,96), Bukti Fisik (-0,11;0,97) dan Daya Tanggap (-0,08;0,97). Berdasarkan analisis IPA, waktu tunggu pelayanan obat dan kejelasan informasi penggunaan obat termasuk dalam prioritas utama perbaikan (Kuadran I), sedangkan atribut yang harus dipertahankan meliputi fasilitas prioritas bagi ibu hamil dan lansia, keramahan petugas, ketersediaan obat, serta pelayanan konseling (Kuadran II). Penelitian ini menunjukkan bahwa perbaikan sistem antrian, optimalisasi SDM farmasi, dan peningkatan komunikasi terapeutik perlu menjadi fokus utama Puskesmas untuk meningkatkan mutu pelayanan kefarmasian dan memperkuat kepercayaan peserta JKN terhadap pelayanan kesehatan primer.
REVIEW: KETERSEDIAAN OBAT INDIKATOR DAN DISPARITAS WILAYAH PADA UPTD FARMASI DINAS KESEHATAN DI INDONESIA Rahmahwati, Dora Dewi; Hermanto, Faizal
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1675

Abstract

Drug availability is one of the main indicators of the quality of health services in Indonesia. Effective drug planning and distribution in the Regional Technical Implementation Unit (UPTD) of the Health Office Pharmacy is key to ensuring public access to essential drugs. This review aims to evaluate drug planning and distribution indicators in the UPTD Pharmacy of Health Offices throughout Indonesia based on recent published studies. A narrative review was conducted through a systematic search of academic databases for the period 2024-2025. Inclusion criteria included studies that evaluated drug planning, distribution, and availability in Indonesian health facilities. Data extracted included study location, study design, sample size, drug availability rate, planning accuracy, and stock-out rate. Of the 12 studies analyzed, drug availability rates varied between 78.5% and 95.2%, with an average of 87.5%. Medicine planning accuracy ranged from 75.2% to 98.5%. Stock-out rates showed significant variation between 4.1% and 22.1%, with an average of 13.7%. The study in Medan with the implementation of Distribution Requirement Planning showed the best results with 95.2% availability and 98.5% planning accuracy. Eastern Indonesia, such as Keerom and East Sumba, showed lower performance with availability below 85%. There are significant disparities in drug planning and distribution between regions in Indonesia. The implementation of integrated information systems and data-based planning methods such as Distribution Requirement Planning can improve drug availability and reduce stockouts. Special attention is needed in remote and eastern regions of Indonesia to improve access to essential drugs.
EFEKTIVITAS DAN IMPLEMENTASI REJIMEN BERBASIS DOLUTEGRAVIR PADA PASIEN HIV DI INDONESIA: TINJAUAN TERHADAP OUTCOME KLINIS DAN TANTANGAN PELAYANAN Hermanto, Faizal; Octora Dewi, Sylvia
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1679

Abstract

Dolutegravir-based regimens, including TLD (Tenofovir-Lamivudine-Dolutegravir), have become the first-line therapy recommended by WHO for HIV treatment. Indonesia has adopted this regimen in accordance with the Minister of Health Regulation No. 23/2022. This review analyzes the clinical effectiveness and implementation of dolutegravir-based regimens in HIV patients based on data from various health facilities in Indonesia. The purpose of this review article is to analyze the clinical outcomes of dolutegravir-based regimens, including viral load suppression, quality of life, and patient adherence. This review was conducted through a comprehensive search in the PubMed and Google Scholar databases for the period 2015-2025. The search query included the keywords “TLD regimen”, “dolutegravir”, “HIV”, “viral load suppression”, “Indonesia”, “clinical effectiveness”, “tenofovir”, and “lamivudine”. Articles were selected based on studies conducted in Indonesian healthcare facilities, involving adult HIV patients receiving dolutegravir-based regimens, and reporting clinical outcomes or program implementation. Six articles met the inclusion criteria and were analyzed. Results showed that dolutegravir-based regimens have good clinical outcomes in various health facilities in Indonesia. Studies in Palembang demonstrated high viral load suppression among patients receiving antiretroviral therapy. Multi-center studies showed significant improvement in quality of life after switching from nevirapine-based to dolutegravir-based regimens. Studies at the primary care level underscored the importance of medication adherence and adequate monitoring. The review concluded that dolutegravir-based regimens demonstrated good clinical effectiveness with diverse outcomes in HIV patients in Indonesia. Implementation requires strengthening viral load monitoring, adherence management, and capacity building at the primary care level.
SYSTEMATIC REVIEW RASIONALITAS ANTIHIPERTENSI PADA PREEKLAMSIA DI BEBERAPA RUMAH SAKIT DI INDONESIA MENGGUNAKAN PENDEKATAN PRISMA Nurfauziah, Yastin; Hermanto, Faizal
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1681

Abstract

Globally, preeclampsia is one of the main contributors to maternal mortality. In Indonesia, discrepancies between clinical practice and guideline recommendations for antihypertensive use in preeclampsia cases remain relatively high, potentially increasing risks for both mothers and fetuses. This study is a PRISMA-based systematic review that aims to evaluate the rational use of antihypertensive drugs in preeclampsia patients across various hospitals in Indonesia. A literature search was conducted in PubMed and Google Scholar for the period 2015–2025, identifying 76 articles, of which 11 met the inclusion and exclusion criteria. Most studies assessed three parameters of rationality—appropriate drug, appropriate indication, and appropriate dose—with mean adherence rates of 92.55%, 91.69%, and 86.73%, respectively. Nifedipine was the most commonly used first-line agent, while methyldopa was frequently used as an alternative or in combination; however, several hospitals still reported the use of drugs that are not recommended, such as candesartan. Variations in practice were mainly related to limited availability of first-line drugs and inconsistent implementation of dosing protocols, as reflected by one hospital where dose appropriateness reached only 5.3%. Overall, the use of antihypertensive therapy for preeclampsia in Indonesia is generally in line with existing guidelines; nevertheless, equitable access to essential medicines and ongoing training for healthcare workers are still needed to address therapy discrepancies arising from resource limitations.
Larvacide Activity of Bungur Plants (Lagerstroemia loudonii T. & B.) Fahrauk Faramayuda; Faizal Hermanto; Ari Sri Windyaswari; Soraya Riyanti; Viola Aditya Nurhayati
Journal of Pharmascience Vol. 9 No. 1 (2022): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i1.9982

Abstract

The prevalence of DHF, especially in Indonesia, is still high. Dengue Hemorrhagic Fever (DHF) is a disease transmitted by the Aedes aegypti species mosquito vector. Therefore, reducing the incidence of DHF requires efforts to break the chain of transmission by inhibiting the growth of the Aedes aegypti mosquito vector. One of the plants that can inhibit the growth of A. aegypti mosquito larvae is the bungur plant. This study aimed to determine the larvicidal activity of ethanol extract of leaves, bark, stems, and fruit of bungur (Lagerstroemia loudonii T. & B.) against A. aegypti larvae. Extraction process used maceration method with 96% ethanol solvent. Phytochemical screening results showed that the ethanol extract of bungur leaves and fruit contains alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids as well as steroids and triterpenoids, whereas in the ethanol extract bungur bark and stems contains alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids. LC50 values of ethanol extract of leaves, bark, stems, and bungur fruit were 374.64 ± 11.88 µg/mL, 396.70 ± 3.99 µg/mL, 425.80 ± 8.15 µg/mL, and 312.54 ± 2.24 µg/mL, consecutively. The results showed that the ethanol extract of the leaves, bark, stems, and fruit of bungur could inhibit the growth of A. aegypti larvae. Ethanol extract of bungur fruit has the best larvicidal activity compared to other test extracts.
Evaluation of The Rationality of Hypertension Medication Use in Puskesmas Central Cimahi Faizal Hermanto; Anna Choirunissa; Titta Hartyana Sutarna; Riza Amelia; Akmal Rizwan
Jurnal Penelitian Pendidikan IPA Vol 10 No 9 (2024): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i9.8673

Abstract

A persistent and abnormal increase in blood pressure in the arteries is known as hypertension (HT. This research aims to assess the consumption of antihypertension at the Puskesmas Central Cimahi. Non-analytical descriptive methods were used in this investigation. Retrospective data was collected by accessing patient prescriptions and medical record data. Fifty-six patient samples in this study met the inclusion requirements. Quantitative and qualitative methods are used to evaluate rationality. Quantitative data analysis is processed to determine the number of patients, gender, age, and type of drug classification. Qualitative data analysis is processed to evaluate the appropiate of the indication, drug, patient and dose. Based on the research results, 52 people suffered from stage 1 hypertension, and four patients suffered from stage 2 hypertension. Amlodipine monotherapy was the most frequently prescribed drug, namely 92%. While the combination of amlodipine, captropil, amlodipine, and hydrochlorothiazide amounted to 4%. The rationality of treating hypertensive patients who meet the right indications, the right drug, the right patient and the right dose is 100%. It can be concluded that the evaluation and use of hypertension medication at the Puskesmas Central Cimahi as a whole meets the criteria for rational treatment.
Co-Authors Abda Abda Abdul Rozzaaq, Muhammad Achmad Zainuddin Ade Kania Ningsih, Ade Kania Adiningsih, Martha Afifah Bambang Sutjiatmo, Afifah Bambang Ahsanul Haq, Fahmi Akhirul Kahfi Syam Akmal Rizwan Alfi Nurul, Islamiyah Amanda Arifianti Essen Andreanus A Soemardji Anna Choirunissa Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Arif Rahman Hakim Diah Lia Aulifa Elin Yulinah Euis Julaeha Fahrauk Faramayuda, Fahrauk Fani Wahyuni, Fani Febrinella, Catellya Fikri Alatas Gusdilla, Windy Haq, Fahmy Ahsanul Hartyana Sutarna, Titta Hasna Hestiary Ratih Imeldha R Pramesty , Putri Lilis Siti Aisyah, Lilis Siti Lutfi, Mutiara Hadi M. Yogi Riyantama Isjoni Mochammad Luthfi Pramukti, Mochammad Luthfi Muchtaridi Muchtaridi Nur Melsandy Nurfauziah, Yastin Nurul Islamiyah, Alfi Octora Dewi, Sylvia Pratama, Gumilar Puspa Sari , Dewi Puspa Sari Dewi Putra , Erwin Ekadharma Rachmawan, Lucky Rachmawan, R. Lucky Rachmawati, Ita Rahmahwati, Dora Dewi Ramdani, Robby Rani Sugandi, Rani Refiani , Aqila Ririn Puspadewi, Ririn Riskia Putri Peratiwi, Riskia Putri Riza Amelia Riza Amelia Riza Amelia Robby, Ramdani Rochmah, Nur Syifa Sembiring, Rinawati Shalsabina, Vina Simatupang, Elivas Siti Nur Aeni, Siti Nur Soraya Riyanti Soraya Riyanti, Soraya Sri Wahyuningsih Suci Nar Vikasari, Suci Nar Suherman, Linda Purnamawati SURYANI Susy Tjahjani Tati Herlina Tri Reksa Saputra, Tri Reksa Unang Supratman Vina Septiani, Vina Viola Aditya Nurhayati Yenny Febriani Yun, Yenny Febriani Yuliana Agustin Zamzami Adnan, Risky